56 items (Bos indicus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GSN	Gelsolin. (846 aa)
	CAPZB	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (306 aa)
	SPTB	Spectrin beta chain; Belongs to the spectrin family. (2331 aa)
	DMTN	Dematin actin binding protein. (467 aa)
	BBS4	Bardet-Biedl syndrome 4. (519 aa)
	TWF1	Twinfilin actin binding protein 1. (368 aa)
	FAM49B	Family with sequence similarity 49 member B. (465 aa)
	KANK1	KN motif and ankyrin repeat domains 1. (1384 aa)
	SPTAN1	Spectrin alpha, non-erythrocytic 1. (2498 aa)
	LOC113879851	Uncharacterized protein. (303 aa)
	A0A4W2CQU2	Uncharacterized protein. (315 aa)
	SVIL	Supervillin. (2301 aa)
	ARFGEF1	ADP ribosylation factor guanine nucleotide exchange factor 1. (1849 aa)
	SPTBN1	Spectrin beta chain; Belongs to the spectrin family. (2350 aa)
	SPTBN4	Spectrin beta, non-erythrocytic 4. (2615 aa)
	CAPG	Capping actin protein, gelsolin like. (412 aa)
	HIP1R	Huntingtin interacting protein 1 related. (1066 aa)
	TMSB10	Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (45 aa)
	MKKS	McKusick-Kaufman syndrome. (570 aa)
	A0A4W2CAT2	MARVEL domain-containing protein. (335 aa)
	TMSB4X	Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (44 aa)
	SSH2	Slingshot protein phosphatase 2. (1429 aa)
	SPTBN2	Spectrin beta chain; Belongs to the spectrin family. (2531 aa)
	VILL	Villin like. (856 aa)
	VIL1	Villin 1. (827 aa)
	TMOD4	Tropomodulin 4. (379 aa)
	PFN4	Profilin; Belongs to the profilin family. (129 aa)
	LMOD2	Leiomodin 2. (585 aa)
	CAPZA3	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (299 aa)
	SSH1	Slingshot protein phosphatase 1. (988 aa)
	TMOD1	Tropomodulin 1. (359 aa)
	PFN2	Profilin; Belongs to the profilin family. (142 aa)
	ADD1	Adducin 1. (769 aa)
	TWF2	Twinfilin actin binding protein 2. (349 aa)
	CAPZA1	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (286 aa)
	ADD3	Adducin 3. (706 aa)
	MYADM	Myeloid associated differentiation marker. (322 aa)
	LOC113879884	Uncharacterized protein. (317 aa)
	RDX	Radixin. (624 aa)
	LMOD1	Leiomodin 1. (578 aa)
	SLIT2	Slit guidance ligand 2. (1543 aa)
	TMOD2	Tropomodulin 2. (351 aa)
	EPS8	Epidermal growth factor receptor pathway substrate 8. (836 aa)
	SCIN	Scinderin. (832 aa)
	KANK3	KN motif and ankyrin repeat domains 3. (876 aa)
	FLII	FLII actin remodeling protein. (1268 aa)
	CAPZA2	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (286 aa)
	AVIL	Advillin. (816 aa)
	TMOD3	Tropomodulin 3. (352 aa)
	SSH3	Slingshot protein phosphatase 3. (649 aa)
	ADD2	Adducin 2. (724 aa)
	SPTA1	Spectrin alpha, erythrocytic 1. (2419 aa)
	FHOD3	Formin homology 2 domain containing 3. (1612 aa)
	PRKCD	Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
	KANK4	KN motif and ankyrin repeat domains 4. (1014 aa)
	LMOD3	Leiomodin 3. (567 aa)

Your Current Organism:

Bos indicus

NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADD1	ADD2	A0A4W2HFD7	A0A4W2E7U5	Adducin 1.	Adducin 2.	0.980
ADD1	ADD3	A0A4W2HFD7	A0A4W2HWH8	Adducin 1.	Adducin 3.	0.961
ADD1	CAPZA2	A0A4W2HFD7	A0A4W2EDI5	Adducin 1.	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.426
ADD1	CAPZB	A0A4W2HFD7	A0A4W2DGI5	Adducin 1.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.629
ADD1	DMTN	A0A4W2HFD7	A0A4W2D8V8	Adducin 1.	Dematin actin binding protein.	0.709
ADD1	TMOD1	A0A4W2HFD7	A0A4W2HBG6	Adducin 1.	Tropomodulin 1.	0.778
ADD1	TMOD2	A0A4W2HFD7	A0A4W2G2L0	Adducin 1.	Tropomodulin 2.	0.520
ADD1	TMOD3	A0A4W2HFD7	A0A4W2EB54	Adducin 1.	Tropomodulin 3.	0.573
ADD1	TMOD4	A0A4W2HFD7	A0A4W2IFP1	Adducin 1.	Tropomodulin 4.	0.699
ADD2	ADD1	A0A4W2E7U5	A0A4W2HFD7	Adducin 2.	Adducin 1.	0.980
ADD2	CAPZB	A0A4W2E7U5	A0A4W2DGI5	Adducin 2.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.602
ADD2	DMTN	A0A4W2E7U5	A0A4W2D8V8	Adducin 2.	Dematin actin binding protein.	0.820
ADD2	RDX	A0A4W2E7U5	A0A4W2GFC5	Adducin 2.	Radixin.	0.424
ADD2	SPTB	A0A4W2E7U5	A0A4W2D9G0	Adducin 2.	Spectrin beta chain; Belongs to the spectrin family.	0.454
ADD2	TMOD1	A0A4W2E7U5	A0A4W2HBG6	Adducin 2.	Tropomodulin 1.	0.710
ADD2	TMOD2	A0A4W2E7U5	A0A4W2G2L0	Adducin 2.	Tropomodulin 2.	0.694
ADD2	TMOD3	A0A4W2E7U5	A0A4W2EB54	Adducin 2.	Tropomodulin 3.	0.693
ADD2	TMOD4	A0A4W2E7U5	A0A4W2IFP1	Adducin 2.	Tropomodulin 4.	0.701
ADD3	ADD1	A0A4W2HWH8	A0A4W2HFD7	Adducin 3.	Adducin 1.	0.961
ADD3	CAPZB	A0A4W2HWH8	A0A4W2DGI5	Adducin 3.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.404

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