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| | PRDM12 | PR domain zinc finger protein 12; Involved in the positive regulation of histone H3-K9 dimethylation; Belongs to the class V-like SAM-binding methyltransferase superfamily. (361 aa) |
| | CTR9 | CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa) |
| | ING2 | Inhibitor of growth protein. (284 aa) |
| | CDK9 | Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (494 aa) |
| | ZNF335 | Zinc finger protein 335. (1342 aa) |
| | OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2. (253 aa) |
| | TET1 | Tet methylcytosine dioxygenase 1. (2137 aa) |
| | MCRS1 | Microspherule protein 1. (462 aa) |
| | SNCA | Alpha-synuclein; Belongs to the synuclein family. (140 aa) |
| | KANSL2 | KAT8 regulatory NSL complex subunit 2. (492 aa) |
| | GCG | Glucagon. (180 aa) |
| | APLNR | Apelin receptor; Belongs to the G-protein coupled receptor 1 family. (368 aa) |
| | EHMT1 | Euchromatic histone lysine methyltransferase 1. (1293 aa) |
| | JDP2 | Jun dimerization protein 2. (174 aa) |
| | IGF2 | Insulin like growth factor 2. (235 aa) |
| | PIH1D1 | PIH1 domain containing 1. (290 aa) |
| | PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (920 aa) |
| | TADA3 | Transcriptional adaptor 3. (432 aa) |
| | NSD3 | Nuclear receptor binding SET domain protein 3. (1439 aa) |
| | MLLT6 | MLLT6, PHD finger containing. (1095 aa) |
| | FOXP3 | Forkhead box P3. (454 aa) |
| | WDR61 | WD_REPEATS_REGION domain-containing protein. (323 aa) |
| | SETD7 | Histone-lysine N-methyltransferase SETD7; Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes. (366 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (499 aa) |
| | TADA2A | Transcriptional adapter. (443 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (456 aa) |
| | DNMT1 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1708 aa) |
| | UCN | Urocortin. (129 aa) |
| | RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa) |
| | JARID2 | Jumonji and AT-rich interaction domain containing 2. (1252 aa) |
| | LMNA | Lamin A/C; Belongs to the intermediate filament family. (664 aa) |
| | RIF1 | Replication timing regulatory factor 1. (2465 aa) |
| | PAXBP1 | PAX3 and PAX7 binding protein 1. (922 aa) |
| | A0A4W2EYN7 | SEA domain-containing protein. (663 aa) |
| | CHTOP | Chromatin target of PRMT1. (277 aa) |
| | UBE2B | Ubiquitin conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family. (180 aa) |
| | A0A4W2EVQ1 | Uncharacterized protein. (127 aa) |
| | A0A4W2EVH0 | Uncharacterized protein. (420 aa) |
| | A0A4W2EV15 | Uncharacterized protein. (301 aa) |
| | NSD1 | Nuclear receptor binding SET domain protein 1. (2698 aa) |
| | TADA2B | Transcriptional adapter. (427 aa) |
| | PRMT6 | Protein arginine methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (375 aa) |
| | SNW1 | SNW domain containing 1. (536 aa) |
| | CTBP1 | C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (441 aa) |
| | KDM4B | Lysine demethylase 4B. (1116 aa) |
| | DR1 | Down-regulator of transcription 1. (176 aa) |
| | PHF19 | PHD finger protein 19. (580 aa) |
| | MTF2 | Metal response element binding transcription factor 2. (593 aa) |
| | PARK7 | Parkinsonism associated deglycase. (190 aa) |
| | SMARCB1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (436 aa) |
| | THAP7 | THAP domain containing 7. (308 aa) |
| | SPI1 | Spi-1 proto-oncogene. (384 aa) |
| | ARRB1 | Arrestin beta 1. (513 aa) |
| | ATG5 | Autophagy protein 5; Involved in autophagic vesicle formation. (214 aa) |
| | BRD7 | Bromodomain containing 7. (853 aa) |
| | UBR5 | Ubiquitin protein ligase E3 component n-recognin 5. (2798 aa) |
| | PAX5 | Paired box 5. (391 aa) |
| | A0A4W2EFV8 | Uncharacterized protein. (691 aa) |
| | SREBF1 | Sterol regulatory element binding transcription factor 1. (1146 aa) |
| | A0A4W2EEW1 | Homeobox domain-containing protein. (234 aa) |
| | SDR16C5 | Short chain dehydrogenase/reductase family 16C member 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (309 aa) |
| | MYB | MYB proto-oncogene, transcription factor. (761 aa) |
| | BRCA1 | BRCA1 DNA repair associated. (1941 aa) |
| | TRIP12 | Thyroid hormone receptor interactor 12. (2040 aa) |
| | ZNF274 | Zinc finger protein 274. (626 aa) |
| | SGF29 | SAGA complex associated factor 29. (293 aa) |
| | PPP4R3B | Protein phosphatase 4 regulatory subunit 3B. (820 aa) |
| | KAT2A | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa) |
| | MBIP | MAP3K12 binding inhibitory protein 1. (343 aa) |
| | SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (1051 aa) |
| | SART3 | Spliceosome associated factor 3, U4/U6 recycling protein. (957 aa) |
| | H2AFY | H2A histone family member Y. (412 aa) |
| | KDM1A | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (877 aa) |
| | NFYC | Nuclear transcription factor Y subunit gamma. (439 aa) |
| | SIRT1 | Sirtuin 1. (734 aa) |
| | CHEK1 | Checkpoint kinase 1. (677 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (553 aa) |
| | PAXIP1 | PAX interacting protein 1. (983 aa) |
| | WDR5 | WD repeat domain 5. (334 aa) |
| | LIF | LIF interleukin 6 family cytokine. (202 aa) |
| | SAP30BP | SAP30 binding protein. (335 aa) |
| | MYOCD | Myocardin. (981 aa) |
| | EHMT2 | Euchromatic histone lysine methyltransferase 2. (1389 aa) |
| | PWWP2B | PWWP domain containing 2B. (539 aa) |
| | OGT | O-linked N-acetylglucosamine (GlcNAc) transferase. (1036 aa) |
| | ZNF451 | Zinc finger protein 451. (1058 aa) |
| | PHF1 | PHD finger protein 1. (603 aa) |
| | OTUB1 | Ubiquitin thioesterase. (291 aa) |
| | KMT2A | Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (3710 aa) |
| | SETD5 | SET domain containing 5. (1478 aa) |
| | SUV39H1 | Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (411 aa) |
| | KAT8 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (458 aa) |
| | CTNNB1 | Catenin beta 1. (774 aa) |
| | A0A4W2BQ69 | Uncharacterized protein. (529 aa) |
| | PPP4C | Serine/threonine-protein phosphatase. (307 aa) |
| | PPP4R2 | Protein phosphatase 4 regulatory subunit 2. (412 aa) |
| | SUPT6H | Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1729 aa) |
| | AUTS2 | Activator of transcription and developmental regulator AUTS2. (1263 aa) |
| | KPNA7 | Importin subunit alpha; Functions in nuclear protein import. (522 aa) |
| | RPS6KA4 | Ribosomal protein S6 kinase. (770 aa) |
| | YEATS2 | YEATS domain containing 2. (1412 aa) |
| | KMT2E | Lysine methyltransferase 2E. (1859 aa) |
| | AKAP8L | A-kinase anchoring protein 8 like; Belongs to the AKAP95 family. (646 aa) |
| | IWS1 | Interacts with SUPT6H, CTD assembly factor 1. (847 aa) |
| | TWIST1 | Twist family bHLH transcription factor 1. (201 aa) |
| | PINK1 | PTEN induced kinase 1. (588 aa) |
| | KDM4A | Uncharacterized protein. (1066 aa) |
| | ZMPSTE24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa) |
| | ZBTB7B | Zinc finger and BTB domain containing 7B. (538 aa) |
| | CTCFL | CCCTC-binding factor like. (662 aa) |
| | MTHFR | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (696 aa) |
| | PIWIL2 | Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family. (969 aa) |
| | BCL6 | BCL6 transcription repressor. (706 aa) |
| | RNF20 | E3 ubiquitin protein ligase; Belongs to the BRE1 family. (975 aa) |
| | NCAPG2 | Non-SMC condensin II complex subunit G2. (1140 aa) |
| | NOC2L | NOC2 like nucleolar associated transcriptional repressor. (754 aa) |
| | A0A4W2D404 | C2H2-type domain-containing protein. (189 aa) |
| | GFI1 | Growth factor independent 1 transcriptional repressor. (436 aa) |
| | RPS6KA5 | Non-specific serine/threonine protein kinase. (945 aa) |
| | SPHK2 | Sphingosine kinase 2. (661 aa) |
| | KANSL3 | KAT8 regulatory NSL complex subunit 3. (989 aa) |
| | ARID5A | AT-rich interaction domain 5A. (592 aa) |
| | KDM5A | Lysine demethylase 5A. (1690 aa) |
| | CCDC197 | Coiled-coil domain containing 197. (290 aa) |
| | KANSL1 | KAT8 regulatory NSL complex subunit 1. (1103 aa) |
| | NIPBL | Nipped-B protein. (2698 aa) |
| | KDM3A | Lysine demethylase 3A. (1340 aa) |
| | CTCF | CCCTC-binding factor. (727 aa) |
| | LOC113903946 | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa) |
| | PARG | Poly(ADP-ribose) glycohydrolase. (946 aa) |
| | RTF1 | RTF1 homolog, Paf1/RNA polymerase II complex component. (714 aa) |
| | LRRK2 | Leucine rich repeat kinase 2. (2527 aa) |
| | GATA3 | GATA binding protein 3. (467 aa) |
| | A0A4W2CWQ4 | WD_REPEATS_REGION domain-containing protein. (191 aa) |
| | A0A4W2CNJ6 | Uncharacterized protein. (191 aa) |
| | INMT | Uncharacterized protein. (293 aa) |
| | RRP8 | Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (460 aa) |
| | DMRTC2 | DMRT like family C2. (369 aa) |
| | TGFB1 | Transforming growth factor beta 1. (443 aa) |
| | C6orf89 | Chromosome 6 open reading frame 89. (355 aa) |
| | KAT7 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa) |
| | PRKD2 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa) |
| | PAF1 | PAF1 homolog, Paf1/RNA polymerase II complex component. (532 aa) |
| | PWWP2A | PWWP domain containing 2A. (754 aa) |
| | ZZZ3 | Uncharacterized protein. (903 aa) |
| | NFYA | Nuclear transcription factor Y subunit alpha. (347 aa) |
| | GLYR1 | Glyoxylate reductase 1 homolog. (553 aa) |
| | PHF20 | PHD finger protein 20. (1010 aa) |
| | SIN3A | SIN3 transcription regulator family member A. (1274 aa) |
| | ISL1 | ISL LIM homeobox 1. (349 aa) |
| | FLCN | UDENN FLCN/SMCR8-type domain-containing protein. (579 aa) |
| | EID1 | Uncharacterized protein. (191 aa) |
