STRINGSTRING
TWF1 TWF1 SPRY2 SPRY2 GABRG2 GABRG2 EPS8L1 EPS8L1 GRIA1 GRIA1 ADAM17 ADAM17 CIB1 CIB1 PAK1 PAK1 CIB3 CIB3 ATP6AP2 ATP6AP2 CFL1 CFL1 AIF1L AIF1L GABRA2 GABRA2 KCNC3 KCNC3 PPP1R9B PPP1R9B SCIMP SCIMP MPP2 MPP2 GABRG3 GABRG3 GABRA1 GABRA1 FAP FAP SH3YL1 SH3YL1 VASP VASP ITGB1 ITGB1 EEF1A1 EEF1A1 EPS8L3 EPS8L3 SRC SRC GABRG1 GABRG1 RHOA RHOA GABRA4 GABRA4 DAGLA DAGLA FGR FGR ITGAV ITGAV PLCG2 PLCG2 WWC1 WWC1 GABRA6 GABRA6 EPB41L5 EPB41L5 EPHA2 EPHA2 EPS8 EPS8 C2CD5 C2CD5 THEM4 THEM4 DPP4 DPP4 OBSCN OBSCN APC2 APC2 PIP5K1A PIP5K1A PLEKHO1 PLEKHO1 A0A4W2ETW4 A0A4W2ETW4 AKAP5 AKAP5 KCNC4 KCNC4 A0A4W2ERB4 A0A4W2ERB4 A0A4W2ER55 A0A4W2ER55 PLEK PLEK ANTXR1 ANTXR1 PLA2G4F PLA2G4F AMPH AMPH A0A4W2EJW5 A0A4W2EJW5 LAMP5 LAMP5 ARHGAP44 ARHGAP44 JCAD JCAD DOCK8 DOCK8 PDPN PDPN SHISA6 SHISA6 A0A4W2E2V5 A0A4W2E2V5 PSD3 PSD3 GABRA5 GABRA5 GPER1 GPER1 ABCA7 ABCA7 ARHGEF2 ARHGEF2 SHISA9 SHISA9 AIF1 AIF1 KCNC1 KCNC1 SHISA8 SHISA8 A0A4W2DPK5 A0A4W2DPK5 KCNA2 KCNA2 EPS8L2 EPS8L2 MYO1D MYO1D APPL2 APPL2 ITGA5 ITGA5 INPP5K INPP5K PSD2 PSD2 CDC42 CDC42 USH2A USH2A SPRY4 SPRY4 KCNC2 KCNC2 A0A4W2DB82 A0A4W2DB82 SGCE SGCE KCNB1 KCNB1 SYNE2 SYNE2 DDX58 DDX58 PTPRK PTPRK EZR EZR LOC113877294 LOC113877294 KANK1 KANK1 CD44 CD44 MYO1G MYO1G RIPOR2 RIPOR2 SLC1A2 SLC1A2 SPTBN1 SPTBN1 RPS3 RPS3 AKT2 AKT2 SHISA7 SHISA7 SNTG1 SNTG1 A0A4W2CEF6 A0A4W2CEF6 HIP1R HIP1R MYO6 MYO6 TRPV1 TRPV1 EGFR EGFR APC APC IFIT5 IFIT5 PDXP PDXP MYO1C MYO1C PSD PSD PLEKHA1 PLEKHA1 PACSIN2 PACSIN2 SPATA13 SPATA13 NME1 NME1 A0A4W2C0I1 A0A4W2C0I1 DLC1 DLC1 MTSS2 MTSS2 A0A4W2BUZ8 A0A4W2BUZ8 RASGRP2 RASGRP2 A0A4W2BTS2 A0A4W2BTS2 SLC39A6 SLC39A6 STX4 STX4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TWF1Twinfilin actin binding protein 1. (368 aa)
SPRY2Sprouty RTK signaling antagonist 2. (315 aa)
GABRG2Gamma-aminobutyric acid type A receptor gamma2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (475 aa)
EPS8L1EPS8 like 1. (784 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (906 aa)
ADAM17ADAM metallopeptidase domain 17. (825 aa)
CIB1Calcium and integrin binding 1. (191 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
CIB3Calcium and integrin binding family member 3. (187 aa)
ATP6AP2Uncharacterized protein. (377 aa)
CFL1Cofilin 1; Belongs to the actin-binding proteins ADF family. (166 aa)
AIF1LAllograft inflammatory factor 1 like. (252 aa)
GABRA2Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (511 aa)
KCNC3Potassium voltage-gated channel subfamily C member 3; Belongs to the potassium channel family. (734 aa)
PPP1R9BProtein phosphatase 1 regulatory subunit 9B. (817 aa)
SCIMPSLP adaptor and CSK interacting membrane protein. (153 aa)
MPP2Membrane palmitoylated protein 2; Belongs to the MAGUK family. (569 aa)
GABRG3Gamma-aminobutyric acid type A receptor gamma3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (467 aa)
GABRA1Gamma-aminobutyric acid type A receptor alpha1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (471 aa)
FAPFibroblast activation protein alpha; Belongs to the peptidase S9B family. (760 aa)
SH3YL1SH3 and SYLF domain containing 1. (374 aa)
VASPVasodilator stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (383 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
EEF1A1Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
EPS8L3EPS8 like 3. (592 aa)
SRCTyrosine-protein kinase. (559 aa)
GABRG1Gamma-aminobutyric acid type A receptor gamma1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (465 aa)
RHOARas homolog family member A. (193 aa)
GABRA4Gamma-aminobutyric acid type A receptor alpha4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (555 aa)
DAGLADiacylglycerol lipase alpha. (1041 aa)
FGRTyrosine-protein kinase. (527 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1266 aa)
WWC1WW and C2 domain containing 1. (1110 aa)
GABRA6Gamma-aminobutyric acid type A receptor alpha6 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (453 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (726 aa)
EPHA2EPH receptor A2. (1007 aa)
EPS8Epidermal growth factor receptor pathway substrate 8. (836 aa)
C2CD5C2 calcium dependent domain containing 5. (1137 aa)
THEM4Thioesterase superfamily member 4. (254 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (747 aa)
OBSCNObscurin, cytoskeletal calmodulin and titin-interacting RhoGEF. (7387 aa)
APC2APC regulator of WNT signaling pathway 2. (2264 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (562 aa)
PLEKHO1Pleckstrin homology domain containing O1. (409 aa)
A0A4W2ETW4Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (474 aa)
AKAP5A-kinase anchoring protein 5. (428 aa)
KCNC4Potassium voltage-gated channel subfamily C member 4; Belongs to the potassium channel family. (659 aa)
A0A4W2ERB4Uncharacterized protein. (242 aa)
A0A4W2ER55Tr-type G domain-containing protein. (120 aa)
PLEKPleckstrin. (348 aa)
ANTXR1ANTXR cell adhesion molecule 1. (564 aa)
PLA2G4FPhospholipase A2. (845 aa)
AMPHAmphiphysin. (853 aa)
A0A4W2EJW5GTP_EFTU_D3 domain-containing protein. (241 aa)
LAMP5Lysosomal associated membrane protein family member 5. (321 aa)
ARHGAP44Rho GTPase activating protein 44. (804 aa)
JCADJunctional cadherin 5 associated. (1305 aa)
DOCK8Dedicator of cytokinesis 8; Belongs to the DOCK family. (2110 aa)
PDPNUncharacterized protein. (169 aa)
SHISA6Shisa family member 6. (552 aa)
A0A4W2E2V5Uncharacterized protein. (424 aa)
PSD3Pleckstrin and Sec7 domain containing 3. (1253 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
ABCA7ATP binding cassette subfamily A member 7. (2152 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (1223 aa)
SHISA9Shisa family member 9. (425 aa)
AIF1Allograft inflammatory factor 1. (147 aa)
KCNC1Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family. (585 aa)
SHISA8Shisa family member 8. (401 aa)
A0A4W2DPK5Tr-type G domain-containing protein. (458 aa)
KCNA2Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family. (499 aa)
EPS8L2EPS8 like 2. (713 aa)
MYO1DMyosin ID; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1006 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (659 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1164 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (449 aa)
PSD2Pleckstrin and Sec7 domain containing 2. (781 aa)
CDC42Cell division cycle 42. (191 aa)
USH2AUsherin. (5204 aa)
SPRY4Sprouty RTK signaling antagonist 4. (321 aa)
KCNC2Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (629 aa)
A0A4W2DB82Tr-type G domain-containing protein. (120 aa)
SGCESarcoglycan epsilon. (496 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
SYNE2Spectrin repeat containing nuclear envelope protein 2. (6919 aa)
DDX58DExD/H-box helicase 58. (941 aa)
PTPRKProtein tyrosine phosphatase receptor type K. (1471 aa)
EZREzrin. (638 aa)
LOC113877294Myotubularin phosphatase domain-containing protein. (543 aa)
KANK1KN motif and ankyrin repeat domains 1. (1384 aa)
CD44CD44 molecule (Indian blood group). (850 aa)
MYO1GMyosin IG; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (995 aa)
RIPOR2PL48 domain-containing protein. (1065 aa)
SLC1A2Amino acid transporter. (595 aa)
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2350 aa)
RPS3Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (281 aa)
AKT2AKT serine/threonine kinase 2. (603 aa)
SHISA7Shisa family member 7. (612 aa)
SNTG1Syntrophin gamma 1. (547 aa)
A0A4W2CEF6Integrin beta; Belongs to the integrin beta chain family. (784 aa)
HIP1RHuntingtin interacting protein 1 related. (1066 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1289 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (837 aa)
EGFRReceptor protein-tyrosine kinase. (1209 aa)
APCAPC regulator of WNT signaling pathway. (2912 aa)
IFIT5Interferon induced protein with tetratricopeptide repeats 5. (482 aa)
PDXPPyridoxal phosphatase; Belongs to the HAD-like hydrolase superfamily. (296 aa)
MYO1CMyosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1098 aa)
PSDPleckstrin and Sec7 domain containing. (1026 aa)
PLEKHA1Pleckstrin homology domain containing A1. (404 aa)
PACSIN2Protein kinase C and casein kinase substrate in neurons 2. (445 aa)
SPATA13Uncharacterized protein. (1260 aa)
NME1Nucleoside diphosphate kinase. (152 aa)
A0A4W2C0I1Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (467 aa)
DLC1DLC1 Rho GTPase activating protein. (1169 aa)
MTSS2MTSS I-BAR domain containing 2. (852 aa)
A0A4W2BUZ8Uncharacterized protein. (402 aa)
RASGRP2RAS guanyl releasing protein 2. (608 aa)
A0A4W2BTS2Tr-type G domain-containing protein. (432 aa)
SLC39A6Solute carrier family 39 member 6. (747 aa)
STX4Syntaxin 4; Belongs to the syntaxin family. (447 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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