STRINGSTRING
GRB2 GRB2 ARFIP1 ARFIP1 MTSS1 MTSS1 PAK1 PAK1 MYADM MYADM PLEKHH2 PLEKHH2 CTTN CTTN CDC42EP5 CDC42EP5 PFN3 PFN3 RHOG RHOG VIL1 VIL1 TMOD4 TMOD4 EDN1 EDN1 WASHC5 WASHC5 FAM49A FAM49A PFN1 PFN1 PFN4 PFN4 MTPN MTPN RASA1 RASA1 PYCARD PYCARD CORO2A CORO2A ARHGAP18 ARHGAP18 LPAR1 LPAR1 PEAK3 PEAK3 S100A10 S100A10 SPTA1 SPTA1 PIK3R1 PIK3R1 RAC3 RAC3 ARPIN ARPIN ARPC4 ARPC4 IQGAP1 IQGAP1 CDC42EP1 CDC42EP1 PDXP PDXP CARMIL1 CARMIL1 BAIAP2L2 BAIAP2L2 SPTBN1 SPTBN1 TGFB1 TGFB1 SPTBN4 SPTBN4 PRKCE PRKCE PLEKHG2 PLEKHG2 CCDC88A CCDC88A ADD1 ADD1 CDK10 CDK10 TWF2 TWF2 NAA80 NAA80 CAPZA1 CAPZA1 ADD3 ADD3 CAPG CAPG WNT11 WNT11 A0A4W2CEF6 A0A4W2CEF6 RICTOR RICTOR PTGER4 PTGER4 DIXDC1 DIXDC1 HIP1R HIP1R MAGEL2 MAGEL2 TMSB10 TMSB10 MKKS MKKS CTNNA2 CTNNA2 BAIAP2L1 BAIAP2L1 ALOX15 ALOX15 A0A4W2CAT2 A0A4W2CAT2 RAC1 RAC1 SSH2 SSH2 ARHGEF10 ARHGEF10 RHPN1 RHPN1 ARPC1A ARPC1A PICK1 PICK1 RHOBTB1 RHOBTB1 CSF3 CSF3 DEF6 DEF6 DLC1 DLC1 DBNL DBNL ARHGAP17 ARHGAP17 SPTBN2 SPTBN2 VILL VILL SIGLEC15 SIGLEC15 CORO1A CORO1A NEDD9 NEDD9 ESAM ESAM CCL24 CCL24 FAM107A FAM107A WASF3 WASF3 A0A4W2BMR3 A0A4W2BMR3 CCL26 CCL26 ARPC1B ARPC1B TMSB4X TMSB4X ARPC5 ARPC5 CDC42EP3 CDC42EP3 CARMIL3 CARMIL3 CAV3 CAV3 BRK1 BRK1 RND2 RND2 STMN1 STMN1 HRAS HRAS LIMK1 LIMK1 SERPINF2 SERPINF2 CORO1B CORO1B STAP1 STAP1 TSC1 TSC1 FHOD3 FHOD3 ACTN2 ACTN2 PHPT1 PHPT1 ARHGAP28 ARHGAP28 CRK CRK SMAD4 SMAD4 PIK3CA PIK3CA A0A4W2DQB1 A0A4W2DQB1 PRKCD PRKCD WAS WAS SYNPO2 SYNPO2 FETUB FETUB KANK4 KANK4 LMOD3 LMOD3 INPP5K INPP5K PAK2 PAK2 RND3 RND3 GSN GSN ARHGEF19 ARHGEF19 ARHGEF18 ARHGEF18 A0A4W2DHL6 A0A4W2DHL6 A0A4W2DHA5 A0A4W2DHA5 TRPM2 TRPM2 CAPZB CAPZB LIMCH1 LIMCH1 CDC42 CDC42 KIAA1211 KIAA1211 HAX1 HAX1 WASL WASL ECT2 ECT2 ARF1 ARF1 SPTB SPTB MYO3B MYO3B DMTN DMTN A0A4W2D8A8 A0A4W2D8A8 A0A4W2D873 A0A4W2D873 BST1 BST1 IQGAP2 IQGAP2 NCKAP1L NCKAP1L PPM1F PPM1F PLEKHH1 PLEKHH1 RHOC RHOC BBS4 BBS4 WDR63 WDR63 DLG1 DLG1 SNX9 SNX9 PHLDB2 PHLDB2 ARHGEF10L ARHGEF10L ROCK1 ROCK1 SFRP1 SFRP1 PROX1 PROX1 CCL21 CCL21 IQGAP3 IQGAP3 CD2AP CD2AP BAIAP2 BAIAP2 FES FES DAAM2 DAAM2 RHOF RHOF IQANK1 IQANK1 AP1AR AP1AR FZD10 FZD10 RHPN2 RHPN2 SH3BP1 SH3BP1 FCHSD2 FCHSD2 NRP1 NRP1 DLG2 DLG2 CDC42EP4 CDC42EP4 ADD2 ADD2 PPM1E PPM1E CFL2 CFL2 GMFG GMFG CARMIL2 CARMIL2 SSH3 SSH3 TESK1 TESK1 TMOD3 TMOD3 AVIL AVIL A0A4W2EBL9 A0A4W2EBL9 ARPC5L ARPC5L CELSR1 CELSR1 ITGB1BP1 ITGB1BP1 CAPZA2 CAPZA2 MET MET FLII FLII GBA2 GBA2 ARHGAP44 ARHGAP44 ARPC2 ARPC2 ARHGEF15 ARHGEF15 ARHGDIA ARHGDIA CCN2 CCN2 ARPC3 ARPC3 ARF6 ARF6 NPHS1 NPHS1 RHOB RHOB ARAP1 ARAP1 FMN1 FMN1 LIMA1 LIMA1 C9orf72 C9orf72 RHOBTB3 RHOBTB3 PLEK PLEK KANK3 KANK3 BRAF BRAF EFNA5 EFNA5 GPR65 GPR65 CAPZA3 CAPZA3 CORO2B CORO2B SSH1 SSH1 TMOD1 TMOD1 PFN2 PFN2 NF2 NF2 RAPGEF3 RAPGEF3 A0A4W2CZR5 A0A4W2CZR5 FER FER C15orf62 C15orf62 TWF1 TWF1 BMP10 BMP10 ROCK2 ROCK2 FAM49B FAM49B HCLS1 HCLS1 TEK TEK PRKN PRKN A0A4W2CX55 A0A4W2CX55 ANKRD23 ANKRD23 RND1 RND1 LATS1 LATS1 ABL1 ABL1 KANK1 KANK1 MTOR MTOR FERMT2 FERMT2 CGNL1 CGNL1 SPTAN1 SPTAN1 LOC113879851 LOC113879851 A0A4W2CQU2 A0A4W2CQU2 MYOC MYOC TGFB3 TGFB3 EPHA1 EPHA1 ARHGEF5 ARHGEF5 WDR1 WDR1 NCKAP1 NCKAP1 NOTCH2 NOTCH2 CCL27 CCL27 PTK2B PTK2B SORBS3 SORBS3 LOC113897295 LOC113897295 A0A4W2EVQ8 A0A4W2EVQ8 A0A4W2EVV4 A0A4W2EVV4 GRHL3 GRHL3 SCIN SCIN ASAP3 ASAP3 ODAM ODAM EPS8 EPS8 TACSTD2 TACSTD2 SYNPO SYNPO RAC2 RAC2 CSF1R CSF1R A0A4W2F1P2 A0A4W2F1P2 CYFIP2 CYFIP2 SEMA3E SEMA3E TMEFF2 TMEFF2 CYFIP1 CYFIP1 MLST8 MLST8 WASF1 WASF1 ELN ELN WASF2 WASF2 COTL1 COTL1 BAG4 BAG4 RHOA RHOA GMFB GMFB ABITRAM ABITRAM PIK3R2 PIK3R2 NCK2 NCK2 FCHSD1 FCHSD1 TMOD2 TMOD2 SLIT2 SLIT2 FSCN1 FSCN1 TTC8 TTC8 F11R F11R LMOD1 LMOD1 CCL11 CCL11 RHOD RHOD RDX RDX LOC113879884 LOC113879884 FHOD1 FHOD1 EPHA3 EPHA3 NTRK3 NTRK3 LMOD2 LMOD2 VASP VASP ARHGAP35 ARHGAP35 TAOK2 TAOK2 NCK1 NCK1 HCK HCK ALMS1 ALMS1 EVL EVL SHANK1 SHANK1 DSTN DSTN SWAP70 SWAP70 NTF3 NTF3 SVIL SVIL TGFBR1 TGFBR1 ARFGEF1 ARFGEF1 TRIM27 TRIM27 MYO3A MYO3A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GRB2Growth factor receptor bound protein 2. (217 aa)
ARFIP1ADP ribosylation factor interacting protein 1. (402 aa)
MTSS1MTSS I-BAR domain containing 1. (798 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
MYADMMyeloid associated differentiation marker. (322 aa)
PLEKHH2Pleckstrin homology, MyTH4 and FERM domain containing H2. (1491 aa)
CTTNCortactin. (538 aa)
CDC42EP5CDC42 effector protein 5. (153 aa)
PFN3Profilin; Belongs to the profilin family. (137 aa)
RHOGRas homolog family member G. (191 aa)
VIL1Villin 1. (827 aa)
TMOD4Tropomodulin 4. (379 aa)
EDN1Endothelin 1. (202 aa)
WASHC5WASH complex subunit 5. (1198 aa)
FAM49AFamily with sequence similarity 49 member A. (323 aa)
PFN1Profilin; Belongs to the profilin family. (140 aa)
PFN4Profilin; Belongs to the profilin family. (129 aa)
MTPNMyotrophin. (118 aa)
RASA1RAS p21 protein activator 1. (1044 aa)
PYCARDPYD and CARD domain containing. (195 aa)
CORO2ACoronin; Belongs to the WD repeat coronin family. (581 aa)
ARHGAP18Rho GTPase activating protein 18. (665 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
PEAK3PEAK family member 3. (466 aa)
S100A10S100 calcium binding protein A10; Belongs to the S-100 family. (97 aa)
SPTA1Spectrin alpha, erythrocytic 1. (2419 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
RAC3Rac family small GTPase 3. (258 aa)
ARPINUncharacterized protein. (226 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (168 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1710 aa)
CDC42EP1CDC42 effector protein 1. (361 aa)
PDXPPyridoxal phosphatase; Belongs to the HAD-like hydrolase superfamily. (296 aa)
CARMIL1Capping protein regulator and myosin 1 linker 1. (1426 aa)
BAIAP2L2BAI1 associated protein 2 like 2. (528 aa)
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2350 aa)
TGFB1Transforming growth factor beta 1. (443 aa)
SPTBN4Spectrin beta, non-erythrocytic 4. (2615 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
PLEKHG2Pleckstrin homology and RhoGEF domain containing G2. (1394 aa)
CCDC88ACoiled-coil domain containing 88A. (1842 aa)
ADD1Adducin 1. (769 aa)
CDK10Cyclin dependent kinase 10; Belongs to the protein kinase superfamily. (361 aa)
TWF2Twinfilin actin binding protein 2. (349 aa)
NAA80N(alpha)-acetyltransferase 80, NatH catalytic subunit. (309 aa)
CAPZA1F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (286 aa)
ADD3Adducin 3. (706 aa)
CAPGCapping actin protein, gelsolin like. (412 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
A0A4W2CEF6Integrin beta; Belongs to the integrin beta chain family. (784 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1789 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (492 aa)
DIXDC1DIX domain containing 1. (683 aa)
HIP1RHuntingtin interacting protein 1 related. (1066 aa)
MAGEL2MAGE family member L2. (1183 aa)
TMSB10Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (45 aa)
MKKSMcKusick-Kaufman syndrome. (570 aa)
CTNNA2Catenin alpha 2. (953 aa)
BAIAP2L1BAI1 associated protein 2 like 1. (536 aa)
ALOX15Arachidonate 15-lipoxygenase. (663 aa)
A0A4W2CAT2MARVEL domain-containing protein. (335 aa)
RAC1Rac family small GTPase 1. (257 aa)
SSH2Slingshot protein phosphatase 2. (1429 aa)
ARHGEF10Rho guanine nucleotide exchange factor 10. (1366 aa)
RHPN1Rhophilin Rho GTPase binding protein 1. (729 aa)
ARPC1AWD_REPEATS_REGION domain-containing protein. (430 aa)
PICK1Protein interacting with PRKCA 1. (464 aa)
RHOBTB1Rho related BTB domain containing 1. (698 aa)
CSF3Colony stimulating factor 3. (215 aa)
DEF6DEF6 guanine nucleotide exchange factor. (701 aa)
DLC1DLC1 Rho GTPase activating protein. (1169 aa)
DBNLDrebrin like. (503 aa)
ARHGAP17Rho GTPase activating protein 17. (871 aa)
SPTBN2Spectrin beta chain; Belongs to the spectrin family. (2531 aa)
VILLVillin like. (856 aa)
SIGLEC15Sialic acid binding Ig like lectin 15. (329 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (830 aa)
ESAMEndothelial cell adhesion molecule. (396 aa)
CCL24C-C motif chemokine ligand 24. (116 aa)
FAM107AFamily with sequence similarity 107 member A. (225 aa)
WASF3WASP family member 3. (501 aa)
A0A4W2BMR3Rho-GAP domain-containing protein. (263 aa)
CCL26C-C motif chemokine. (94 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (372 aa)
TMSB4XThymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (44 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
CDC42EP3CDC42 effector protein 3. (254 aa)
CARMIL3Capping protein regulator and myosin 1 linker 3. (1372 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa)
RND2Rho family GTPase 2. (227 aa)
STMN1Uncharacterized protein. (295 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
LIMK1LIM domain kinase 1. (778 aa)
SERPINF2Serpin family F member 2; Belongs to the serpin family. (492 aa)
CORO1BCoronin; Belongs to the WD repeat coronin family. (488 aa)
STAP1Signal transducing adaptor family member 1. (288 aa)
TSC1TSC complex subunit 1. (1165 aa)
FHOD3Formin homology 2 domain containing 3. (1612 aa)
ACTN2Actinin alpha 2. (894 aa)
PHPT1Phosphohistidine phosphatase 1. (125 aa)
ARHGAP28Rho GTPase activating protein 28. (755 aa)
CRKCRK proto-oncogene, adaptor protein. (376 aa)
SMAD4Mothers against decapentaplegic homolog. (553 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
A0A4W2DQB1Coronin; Belongs to the WD repeat coronin family. (262 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
WASWASP actin nucleation promoting factor. (559 aa)
SYNPO2Synaptopodin 2. (1259 aa)
FETUBUncharacterized protein. (705 aa)
KANK4KN motif and ankyrin repeat domains 4. (1014 aa)
LMOD3Leiomodin 3. (567 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (449 aa)
PAK2Non-specific serine/threonine protein kinase. (600 aa)
RND3Rho family GTPase 3. (244 aa)
GSNGelsolin. (846 aa)
ARHGEF19Rho guanine nucleotide exchange factor 19. (807 aa)
ARHGEF18Uncharacterized protein. (1345 aa)
A0A4W2DHL6Uncharacterized protein. (165 aa)
A0A4W2DHA5Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (159 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1499 aa)
CAPZBF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (306 aa)
LIMCH1LIM and calponin homology domains 1. (1570 aa)
CDC42Cell division cycle 42. (191 aa)
KIAA1211KIAA1211. (1391 aa)
HAX1HCLS1 associated protein X-1. (287 aa)
WASLWASP like actin nucleation promoting factor. (511 aa)
ECT2Epithelial cell transforming 2. (944 aa)
ARF1ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
SPTBSpectrin beta chain; Belongs to the spectrin family. (2331 aa)
MYO3BMyosin IIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1340 aa)
DMTNDematin actin binding protein. (467 aa)
A0A4W2D8A8BTB domain-containing protein. (666 aa)
A0A4W2D873Uncharacterized protein. (99 aa)
BST1Bone marrow stromal cell antigen 1. (371 aa)
IQGAP2IQ motif containing GTPase activating protein 2. (1575 aa)
NCKAP1LNCK associated protein 1 like. (1134 aa)
PPM1FProtein phosphatase, Mg2+/Mn2+ dependent 1F. (672 aa)
PLEKHH1Pleckstrin homology, MyTH4 and FERM domain containing H1. (1359 aa)
RHOCRas homolog family member C. (193 aa)
BBS4Bardet-Biedl syndrome 4. (519 aa)
WDR63WD repeat domain 63. (892 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa)
SNX9Sorting nexin. (624 aa)
PHLDB2Pleckstrin homology like domain family B member 2. (1343 aa)
ARHGEF10LRho guanine nucleotide exchange factor 10 like. (1120 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1356 aa)
SFRP1Secreted frizzled related protein 1. (307 aa)
PROX1Prospero homeobox 1. (738 aa)
CCL21C-C motif chemokine ligand 21. (133 aa)
IQGAP3IQ motif containing GTPase activating protein 3. (1635 aa)
CD2APCD2 associated protein. (766 aa)
BAIAP2BAI1 associated protein 2. (568 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
DAAM2Dishevelled associated activator of morphogenesis 2. (1074 aa)
RHOFRas homolog family member F, filopodia associated. (215 aa)
IQANK1IQ motif and ankyrin repeat containing 1. (591 aa)
AP1ARAdaptor related protein complex 1 associated regulatory protein. (302 aa)
FZD10Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
RHPN2Rhophilin Rho GTPase binding protein 2. (686 aa)
SH3BP1Uncharacterized protein. (693 aa)
FCHSD2FCH and double SH3 domains 2. (764 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
DLG2Discs large MAGUK scaffold protein 2. (1009 aa)
CDC42EP4CDC42 effector protein 4. (351 aa)
ADD2Adducin 2. (724 aa)
PPM1EProtein phosphatase, Mg2+/Mn2+ dependent 1E. (754 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
GMFGGlia maturation factor gamma. (182 aa)
CARMIL2Uncharacterized protein. (1372 aa)
SSH3Slingshot protein phosphatase 3. (649 aa)
TESK1Testis associated actin remodelling kinase 1. (630 aa)
TMOD3Tropomodulin 3. (352 aa)
AVILAdvillin. (816 aa)
A0A4W2EBL9Uncharacterized protein. (1267 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (3045 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
CAPZA2F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (286 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1384 aa)
FLIIFLII actin remodeling protein. (1268 aa)
GBA2Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. (906 aa)
ARHGAP44Rho GTPase activating protein 44. (804 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (300 aa)
ARHGEF15Rho guanine nucleotide exchange factor 15. (847 aa)
ARHGDIARho GDP dissociation inhibitor alpha. (204 aa)
CCN2Cellular communication network factor 2. (464 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (190 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (148 aa)
NPHS1NPHS1 adhesion molecule, nephrin. (1242 aa)
RHOBRas homolog family member B. (181 aa)
ARAP1ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1. (1740 aa)
FMN1Formin 1. (1419 aa)
LIMA1LIM domain and actin binding 1. (761 aa)
C9orf72C9orf72-SMCR8 complex subunit. (481 aa)
RHOBTB3Rho related BTB domain containing 3. (912 aa)
PLEKPleckstrin. (348 aa)
KANK3KN motif and ankyrin repeat domains 3. (876 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (805 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (254 aa)
GPR65G protein-coupled receptor 65; Belongs to the G-protein coupled receptor 1 family. (334 aa)
CAPZA3F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (299 aa)
CORO2BCoronin; Belongs to the WD repeat coronin family. (503 aa)
SSH1Slingshot protein phosphatase 1. (988 aa)
TMOD1Tropomodulin 1. (359 aa)
PFN2Profilin; Belongs to the profilin family. (142 aa)
NF2Neurofibromin 2. (596 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (923 aa)
A0A4W2CZR5Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (406 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (821 aa)
C15orf62Chromosome 15 open reading frame 62. (176 aa)
TWF1Twinfilin actin binding protein 1. (368 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1469 aa)
FAM49BFamily with sequence similarity 49 member B. (465 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (485 aa)
TEKTEK receptor tyrosine kinase. (1125 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (460 aa)
A0A4W2CX55Uncharacterized protein. (245 aa)
ANKRD23ANK_REP_REGION domain-containing protein. (507 aa)
RND1Rho family GTPase 1. (232 aa)
LATS1Large tumor suppressor kinase 1. (1123 aa)
ABL1Tyrosine-protein kinase. (1151 aa)
KANK1KN motif and ankyrin repeat domains 1. (1384 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
FERMT2Fermitin family member 2. (706 aa)
CGNL1Cingulin like 1. (1293 aa)
SPTAN1Spectrin alpha, non-erythrocytic 1. (2498 aa)
LOC113879851Uncharacterized protein. (303 aa)
A0A4W2CQU2Uncharacterized protein. (315 aa)
MYOCMyocilin. (490 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (452 aa)
EPHA1EPH receptor A1. (1076 aa)
ARHGEF5Rho guanine nucleotide exchange factor 5. (1655 aa)
WDR1WD repeat domain 1. (606 aa)
NCKAP1NCK associated protein 1. (1139 aa)
NOTCH2Notch receptor 2. (2471 aa)
CCL27C-C motif chemokine ligand 27. (119 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1008 aa)
SORBS3Sorbin and SH3 domain containing 3. (783 aa)
LOC113897295Uncharacterized protein. (736 aa)
A0A4W2EVQ8Uncharacterized protein; Belongs to the profilin family. (69 aa)
A0A4W2EVV4Profilin; Belongs to the profilin family. (87 aa)
GRHL3Grainyhead like transcription factor 3. (638 aa)
SCINScinderin. (832 aa)
ASAP3ArfGAP with SH3 domain, ankyrin repeat and PH domain 3. (883 aa)
ODAMOdontogenic, ameloblast associated. (277 aa)
EPS8Epidermal growth factor receptor pathway substrate 8. (836 aa)
TACSTD2Tumor associated calcium signal transducer 2. (319 aa)
SYNPOSynaptopodin. (1131 aa)
RAC2Rac family small GTPase 2. (209 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1046 aa)
A0A4W2F1P2ANAPC4_WD40 domain-containing protein. (204 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (763 aa)
TMEFF2Transmembrane protein with EGF like and two follistatin like domains 2. (429 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
MLST8MTOR associated protein, LST8 homolog. (326 aa)
WASF1WASP family member 1. (570 aa)
ELNElastin. (760 aa)
WASF2WASP family member 2. (493 aa)
COTL1Coactosin like F-actin binding protein 1. (142 aa)
BAG4BCL2 associated athanogene 4. (457 aa)
RHOARas homolog family member A. (193 aa)
GMFBGlia maturation factor; Belongs to the actin-binding proteins ADF family. GMF subfamily. (142 aa)
ABITRAMActin binding transcription modulator. (187 aa)
PIK3R2Uncharacterized protein. (724 aa)
NCK2Cytoplasmic protein. (376 aa)
FCHSD1FCH and double SH3 domains 1. (692 aa)
TMOD2Tropomodulin 2. (351 aa)
SLIT2Slit guidance ligand 2. (1543 aa)
FSCN1Fascin. (493 aa)
TTC8Tetratricopeptide repeat domain 8. (501 aa)
F11RF11 receptor. (298 aa)
LMOD1Leiomodin 1. (578 aa)
CCL11C-C motif chemokine. (97 aa)
RHODRas homolog family member D. (210 aa)
RDXRadixin. (624 aa)
LOC113879884Uncharacterized protein. (317 aa)
FHOD1Formin homology 2 domain containing 1. (1228 aa)
EPHA3EPH receptor A3. (984 aa)
NTRK3Tyrosine-protein kinase receptor. (864 aa)
LMOD2Leiomodin 2. (585 aa)
VASPVasodilator stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (383 aa)
ARHGAP35Rho GTPase activating protein 35. (1500 aa)
TAOK2TAO kinase 2. (1125 aa)
NCK1Cytoplasmic protein. (377 aa)
HCKTyrosine-protein kinase. (558 aa)
ALMS1ALMS1 centrosome and basal body associated protein. (4304 aa)
EVLEnah/Vasp-like. (455 aa)
SHANK1SH3 and multiple ankyrin repeat domains 1. (2179 aa)
DSTNDestrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family. (165 aa)
SWAP70Switching B cell complex subunit SWAP70. (585 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (297 aa)
SVILSupervillin. (2301 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
ARFGEF1ADP ribosylation factor guanine nucleotide exchange factor 1. (1849 aa)
TRIM27Tripartite motif containing 27. (513 aa)
MYO3AMyosin IIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1623 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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