node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A0A4W2BZA0 | TP53 | A0A4W2BZA0 | A0A4W2I2P0 | Fork-head domain-containing protein. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.536 |
A0A4W2EYN7 | TP53 | A0A4W2EYN7 | A0A4W2I2P0 | SEA domain-containing protein. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.622 |
BRCA2 | CHEK2 | A0A4W2BPN3 | A0A4W2E5N2 | BRCA2 DNA repair associated. | Checkpoint kinase 2. | 0.757 |
BRCA2 | KAT5 | A0A4W2BPN3 | A0A4W2BTJ3 | BRCA2 DNA repair associated. | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. | 0.424 |
BRCA2 | TP53 | A0A4W2BPN3 | A0A4W2I2P0 | BRCA2 DNA repair associated. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.868 |
CDKN1A | TFAP4 | A0A4W2EED6 | A0A4W2FCI5 | Cyclin dependent kinase inhibitor 1A. | Transcription factor AP-4. | 0.895 |
CDKN1A | TP53 | A0A4W2EED6 | A0A4W2I2P0 | Cyclin dependent kinase inhibitor 1A. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.995 |
CHEK2 | BRCA2 | A0A4W2E5N2 | A0A4W2BPN3 | Checkpoint kinase 2. | BRCA2 DNA repair associated. | 0.757 |
CHEK2 | KAT5 | A0A4W2E5N2 | A0A4W2BTJ3 | Checkpoint kinase 2. | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. | 0.453 |
CHEK2 | TP53 | A0A4W2E5N2 | A0A4W2I2P0 | Checkpoint kinase 2. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.979 |
FOXM1 | TP53 | A0A4W2EGH5 | A0A4W2I2P0 | Fork-head domain-containing protein. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.536 |
HIPK2 | TP53 | A0A4W2EPL0 | A0A4W2I2P0 | Homeodomain interacting protein kinase 2. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.986 |
ING4 | KAT5 | A0A4W2CP70 | A0A4W2BTJ3 | Inhibitor of growth protein. | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. | 0.596 |
ING4 | TP53 | A0A4W2CP70 | A0A4W2I2P0 | Inhibitor of growth protein. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.691 |
KAT5 | BRCA2 | A0A4W2BTJ3 | A0A4W2BPN3 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. | BRCA2 DNA repair associated. | 0.424 |
KAT5 | CHEK2 | A0A4W2BTJ3 | A0A4W2E5N2 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. | Checkpoint kinase 2. | 0.453 |
KAT5 | ING4 | A0A4W2BTJ3 | A0A4W2CP70 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. | Inhibitor of growth protein. | 0.596 |
KAT5 | TP53 | A0A4W2BTJ3 | A0A4W2I2P0 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.863 |
TFAP4 | CDKN1A | A0A4W2FCI5 | A0A4W2EED6 | Transcription factor AP-4. | Cyclin dependent kinase inhibitor 1A. | 0.895 |
TP53 | A0A4W2BZA0 | A0A4W2I2P0 | A0A4W2BZA0 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Fork-head domain-containing protein. | 0.536 |