STRINGSTRING
KAT5 KAT5 BRCA2 BRCA2 TP53 TP53 TFAP4 TFAP4 A0A4W2EYN7 A0A4W2EYN7 HIPK2 HIPK2 RPS27L RPS27L FOXM1 FOXM1 CDKN1A CDKN1A MAD2L2 MAD2L2 CHEK2 CHEK2 ING4 ING4 A0A4W2C0C3 A0A4W2C0C3 A0A4W2BZA0 A0A4W2BZA0
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa)
BRCA2BRCA2 DNA repair associated. (3420 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (499 aa)
TFAP4Transcription factor AP-4. (335 aa)
A0A4W2EYN7SEA domain-containing protein. (663 aa)
HIPK2Homeodomain interacting protein kinase 2. (1205 aa)
RPS27L40S ribosomal protein S27. (102 aa)
FOXM1Fork-head domain-containing protein. (760 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (161 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (211 aa)
CHEK2Checkpoint kinase 2. (534 aa)
ING4Inhibitor of growth protein. (248 aa)
A0A4W2C0C340S ribosomal protein S27. (95 aa)
A0A4W2BZA0Fork-head domain-containing protein. (697 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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