STRINGSTRING
CLDN5 CLDN5 PLVAP PLVAP SLIT2 SLIT2 ARHGAP35 ARHGAP35 DDAH1 DDAH1 MYLK3 MYLK3 UCN UCN C2CD4B C2CD4B CTNNBIP1 CTNNBIP1 OCLN OCLN APOE APOE TJP3 TJP3 TJP2 TJP2 TRPV4 TRPV4 BCR BCR ANGPT1 ANGPT1 RAMP2 RAMP2 FGFBP3 FGFBP3 BMP6 BMP6 CDH5 CDH5 TJP1 TJP1 PTPRJ PTPRJ A0A4W2EBL8 A0A4W2EBL8 FERMT2 FERMT2 PDE2A PDE2A PLEC PLEC SH3GL2 SH3GL2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
PLVAPPlasmalemma vesicle associated protein. (442 aa)
SLIT2Slit guidance ligand 2. (1543 aa)
ARHGAP35Rho GTPase activating protein 35. (1500 aa)
DDAH1Dimethylarginine dimethylaminohydrolase 1. (408 aa)
MYLK3Myosin light chain kinase 3. (786 aa)
UCNUrocortin. (129 aa)
C2CD4BUncharacterized protein. (468 aa)
CTNNBIP1Catenin beta interacting protein 1. (81 aa)
OCLNOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (522 aa)
APOEApolipoprotein E. (349 aa)
TJP3Tight junction protein 3; Belongs to the MAGUK family. (931 aa)
TJP2Uncharacterized protein; Belongs to the MAGUK family. (1174 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (803 aa)
BCRBCR activator of RhoGEF and GTPase. (1283 aa)
ANGPT1Angiopoietin 1. (498 aa)
RAMP2Receptor activity modifying protein 2. (182 aa)
FGFBP3Fibroblast growth factor binding protein 3. (257 aa)
BMP6Bone morphogenetic protein 6. (525 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (783 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1855 aa)
PTPRJPeptidylprolyl isomerase. (1344 aa)
A0A4W2EBL8Uncharacterized protein. (333 aa)
FERMT2Fermitin family member 2. (706 aa)
PDE2APhosphodiesterase. (943 aa)
PLECPlectin. (4671 aa)
SH3GL2SH3 domain containing GRB2 like 2, endophilin A1. (352 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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