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PIF1 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (649 aa) | ||||
HELB | DNA helicase B. (1136 aa) | ||||
IGHMBP2 | Immunoglobulin mu DNA binding protein 2. (981 aa) | ||||
BRIP1 | BRCA1 interacting protein C-terminal helicase 1. (1172 aa) | ||||
DNA2 | DNA replication helicase/nuclease 2. (1061 aa) | ||||
ERCC2 | ERCC excision repair 2, TFIIH core complex helicase subunit. (800 aa) |