STRINGSTRING
RUNX2 RUNX2 BHLHE40 BHLHE40 PSMD9 PSMD9 USF1 USF1 IKZF4 IKZF4 FHL2 FHL2 ISL1 ISL1 ID3 ID3 KLF5 KLF5 SMAD3 SMAD3 TCF15 TCF15 MAP3K10 MAP3K10 FIGLA FIGLA KDM1A KDM1A SIRT1 SIRT1 HAND1 HAND1 CREBBP CREBBP TWIST1 TWIST1 ASCL1 ASCL1 TCF3 TCF3 BHLHE41 BHLHE41 TCF21 TCF21 NCAPG2 NCAPG2 SCX SCX FOXH1 FOXH1 MYOD1 MYOD1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RUNX2RUNX family transcription factor 2. (527 aa)
BHLHE40Basic helix-loop-helix family member e40. (412 aa)
PSMD9PDZ domain-containing protein. (221 aa)
USF1Upstream transcription factor 1. (310 aa)
IKZF4IKAROS family zinc finger 4. (585 aa)
FHL2Four and a half LIM domains 2. (279 aa)
ISL1ISL LIM homeobox 1. (349 aa)
ID3Inhibitor of DNA binding 3, HLH protein. (119 aa)
KLF5Kruppel like factor 5. (454 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
TCF15Transcription factor 15. (197 aa)
MAP3K10Mitogen-activated protein kinase kinase kinase. (947 aa)
FIGLABHLH domain-containing protein. (207 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (877 aa)
SIRT1Sirtuin 1. (734 aa)
HAND1Heart and neural crest derivatives expressed 1. (394 aa)
CREBBPCREB binding protein. (2435 aa)
TWIST1Twist family bHLH transcription factor 1. (201 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (219 aa)
TCF3Transcription factor 3. (640 aa)
BHLHE41Basic helix-loop-helix family member e41. (485 aa)
TCF21Transcription factor 21. (179 aa)
NCAPG2Non-SMC condensin II complex subunit G2. (1140 aa)
SCXScleraxis bHLH transcription factor. (202 aa)
FOXH1Forkhead box H1. (359 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (318 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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