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| | BHLHE40 | Basic helix-loop-helix family member e40. (412 aa) |
| | USP7 | Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1103 aa) |
| | PKD1 | Polycystin 1, transient receptor potential channel interacting. (4303 aa) |
| | IRAK2 | Interleukin 1 receptor associated kinase 2. (621 aa) |
| | MED13 | Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2174 aa) |
| | TBX6 | T-box transcription factor 6. (437 aa) |
| | CCDC22 | Coiled-coil domain containing 22. (594 aa) |
| | PLA2G10 | Phospholipase A(2). (159 aa) |
| | BRMS1 | BRMS1 transcriptional repressor and anoikis regulator. (246 aa) |
| | PKHD1 | PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (4060 aa) |
| | TRAIP | TRAF interacting protein. (472 aa) |
| | CDK5RAP3 | CDK5 regulatory subunit associated protein 3. (505 aa) |
| | PIM1 | Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (313 aa) |
| | SUFU | Suppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (485 aa) |
| | FOXH1 | Forkhead box H1. (359 aa) |
| | NFKBIL1 | NFKB inhibitor like 1. (329 aa) |
| | TRIM40 | Uncharacterized protein. (368 aa) |
| | PARP10 | Poly [ADP-ribose] polymerase. (957 aa) |
| | ERBIN | Erbb2 interacting protein. (1460 aa) |
| | NLRC5 | NLR family CARD domain containing 5. (1862 aa) |
| | PELI1 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa) |
| | A0A4W2CEA8 | Uncharacterized protein. (102 aa) |
| | WWP2 | E3 ubiquitin-protein ligase. (887 aa) |
| | UFL1 | UFM1 specific ligase 1. (792 aa) |
| | A0A4W2CFE6 | COMM domain-containing protein. (85 aa) |
| | TRIM21 | Tripartite motif containing 21. (511 aa) |
| | OTULINL | OTU deubiquitinase with linear linkage specificity like. (354 aa) |
| | NLRP12 | NLR family pyrin domain containing 12. (916 aa) |
| | BCL3 | BCL3 transcription coactivator. (454 aa) |
| | SRI | Sorcin. (198 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa) |
| | FOXA2 | Forkhead box A2. (467 aa) |
| | CTNNBIP1 | Catenin beta interacting protein 1. (81 aa) |
| | GAS6 | Growth arrest specific 6. (671 aa) |
| | ITCH | E3 ubiquitin-protein ligase. (862 aa) |
| | IRAK3 | Interleukin 1 receptor associated kinase 3. (615 aa) |
| | RBCK1 | RANBP2-type and C3HC4-type zinc finger containing 1. (510 aa) |
| | ID2 | Inhibitor of DNA binding 2. (134 aa) |
| | CACTIN | Cactin, spliceosome C complex subunit. (756 aa) |
| | TMIGD3 | Transmembrane and immunoglobulin domain containing 3; Belongs to the G-protein coupled receptor 1 family. (347 aa) |
| | EZH2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit. (779 aa) |
| | PTCH1 | Patched 1. (1453 aa) |
| | PIAS4 | Protein inhibitor of activated STAT 4. (573 aa) |
| | TAX1BP1 | Tax1 binding protein 1. (817 aa) |
| | CAT | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family. (593 aa) |
| | FZD6 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (714 aa) |
| | HEYL | Hes related family bHLH transcription factor with YRPW motif like. (329 aa) |
| | ZC3H12A | Zinc finger CCCH-type containing 12A. (583 aa) |
| | HES6 | Hes family bHLH transcription factor 6. (225 aa) |
| | PKD2 | Polycystin 2, transient receptor potential cation channel. (1071 aa) |
| | CYS1 | Cystin 1. (158 aa) |
| | COMMD7 | Uncharacterized protein. (271 aa) |
| | TWIST1 | Twist family bHLH transcription factor 1. (201 aa) |
| | NWD2 | NACHT and WD repeat domain containing 2. (1742 aa) |
| | TBXT | T-box transcription factor T. (435 aa) |
| | ANXA4 | Annexin. (321 aa) |
| | HES1 | Hes family bHLH transcription factor 1. (280 aa) |
| | HAND1 | Heart and neural crest derivatives expressed 1. (394 aa) |
| | SIGIRR | Single Ig and TIR domain containing. (479 aa) |
| | TRIM37 | Tripartite motif containing 37. (961 aa) |
| | WFS1 | Wolframin ER transmembrane glycoprotein. (888 aa) |
| | NLRC3 | NLR family CARD domain containing 3. (1065 aa) |
| | PAXIP1 | PAX interacting protein 1. (983 aa) |
| | SIRT1 | Sirtuin 1. (734 aa) |
| | KDM1A | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (877 aa) |
| | LRRC14 | Leucine rich repeat containing 14. (493 aa) |
| | PROX1 | Prospero homeobox 1. (738 aa) |
| | CYLD | CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (956 aa) |
| | ADGRG3 | Adhesion G protein-coupled receptor G3; Belongs to the G-protein coupled receptor 2 family. (547 aa) |
| | HAVCR2 | Hepatitis A virus cellular receptor 2. (290 aa) |
| | PRMT2 | Protein arginine methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (434 aa) |
| | CEBPG | CCAAT enhancer binding protein gamma. (149 aa) |
| | KEAP1 | Kelch like ECH associated protein 1. (623 aa) |
| | SFRP5 | Secreted frizzled related protein 5. (315 aa) |
| | ARRB2 | Arrestin beta 2. (409 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1013 aa) |
| | CREB3 | cAMP responsive element binding protein 3. (365 aa) |
| | COMMD1 | Copper metabolism domain containing 1. (196 aa) |
| | PEX14 | Peroxisomal biogenesis factor 14. (373 aa) |
| | NFKBIB | NFKB inhibitor beta. (357 aa) |
| | MAD2L2 | Mitotic arrest deficient 2 like 2. (211 aa) |
| | TFDP1 | Transcription factor. (410 aa) |
| | TAF3 | TATA-box binding protein associated factor 3. (932 aa) |
| | DAB2IP | DAB2 interacting protein. (1267 aa) |
| | TNFAIP3 | TNF alpha induced protein 3. (780 aa) |
| | MAP3K10 | Mitogen-activated protein kinase kinase kinase. (947 aa) |
| | TRIB1 | Tribbles pseudokinase 1. (372 aa) |
| | NR0B2 | Nuclear receptor subfamily 0 group B member 2. (260 aa) |
| | CYP1B1 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (539 aa) |
| | PTGIS | Prostaglandin I2 synthase. (543 aa) |
| | CHP1 | Calcineurin like EF-hand protein 1. (195 aa) |
| | OTULIN | OTU deubiquitinase with linear linkage specificity. (509 aa) |
| | ARRB1 | Arrestin beta 1. (513 aa) |
| | NLRP2 | NLR family pyrin domain containing 2. (974 aa) |
| | SPI1 | Spi-1 proto-oncogene. (384 aa) |
| | RWDD3 | RWD domain containing 3. (267 aa) |
| | A0A4W2EUZ6 | RING-type domain-containing protein. (58 aa) |
| | NWD1 | NACHT and WD repeat domain containing 1. (1565 aa) |
| | SIK1 | Uncharacterized protein. (778 aa) |
| | CMKLR1 | Chemerin chemokine-like receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa) |
| | SFRP4 | Secreted frizzled related protein 4. (346 aa) |
| | ID3 | Inhibitor of DNA binding 3, HLH protein. (119 aa) |
| | FOXJ1 | Forkhead box J1. (421 aa) |
| | A0A4W2FDM7 | TIR domain-containing protein. (1029 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (774 aa) |
| | PURA | Purine rich element binding protein A. (322 aa) |
| | MEN1 | Menin 1. (610 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | TCF7L2 | Transcription factor 7 like 2. (652 aa) |
| | NR1H4 | Nuclear receptor subfamily 1 group H member 4. (486 aa) |
| | ESR1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (596 aa) |
| | SETD6 | N-lysine methyltransferase SETD6; Protein-lysine N-methyltransferase. Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily. (450 aa) |
| | LRRC7 | Leucine rich repeat containing 7. (1594 aa) |
| | NUPR1 | Nuclear protein 1, transcriptional regulator. (82 aa) |
| | EGLN1 | Uncharacterized protein. (420 aa) |
| | RNF2 | Ring finger protein 2. (336 aa) |
| | SMAD7 | Mothers against decapentaplegic homolog. (426 aa) |
| | ID1 | Inhibitor of DNA binding 1, HLH protein. (154 aa) |
| | E2F1 | E2F transcription factor 1. (437 aa) |
| | HDAC2 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa) |
| | FOXP3 | Forkhead box P3. (454 aa) |
| | GLIS2 | GLIS family zinc finger 2. (524 aa) |
| | PHB2 | Prohibitin. (299 aa) |
| | RB1 | RB transcriptional corepressor 1. (928 aa) |
| | NFKBIA | NFKB inhibitor alpha. (314 aa) |
| | NDN | Necdin, MAGE family member. (350 aa) |
| | HAND2 | Heart and neural crest derivatives expressed 2. (217 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
