60 items (Bos indicus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GIPC1	GIPC PDZ domain containing family member 1. (333 aa)
	GIPC2	GIPC PDZ domain containing family member 2. (316 aa)
	PAXIP1	PAX interacting protein 1. (983 aa)
	GPX1	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (204 aa)
	CORO1B	Coronin; Belongs to the WD repeat coronin family. (488 aa)
	A0A4W2DSW5	Uncharacterized protein. (191 aa)
	GPLD1	Glycosylphosphatidylinositol specific phospholipase D1. (843 aa)
	LGALS8	Galectin. (357 aa)
	VEGFA	Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (394 aa)
	CLEC14A	C-type lectin domain containing 14A. (475 aa)
	CDH5	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (783 aa)
	NRP1	Neuropilin; Belongs to the neuropilin family. (923 aa)
	ADGRA2	Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1343 aa)
	FGF2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
	CYP1B1	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (539 aa)
	FSTL1	Follistatin like 1. (495 aa)
	MMRN2	Multimerin 2. (932 aa)
	VSTM4	V-set and transmembrane domain containing 4. (319 aa)
	GIPC3	GIPC PDZ domain containing family member 3. (318 aa)
	A0A4W2EQZ6	Uncharacterized protein. (832 aa)
	DPP4	Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (747 aa)
	PIK3R3	Uncharacterized protein. (461 aa)
	MYH9	Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1986 aa)
	S100Z	Protein S100; Belongs to the S-100 family. (99 aa)
	RHOA	Ras homolog family member A. (193 aa)
	PRKX	Uncharacterized protein; Belongs to the protein kinase superfamily. (347 aa)
	AKT1	Non-specific serine/threonine protein kinase. (747 aa)
	NR4A1	Nuclear receptor subfamily 4 group A member 1. (598 aa)
	SLIT2	Slit guidance ligand 2. (1543 aa)
	SCARB1	Scavenger receptor class B member 1; Belongs to the CD36 family. (586 aa)
	GREM1	Gremlin 1, DAN family BMP antagonist. (240 aa)
	ITGB1	Integrin beta; Belongs to the integrin beta chain family. (801 aa)
	FAP	Fibroblast activation protein alpha; Belongs to the peptidase S9B family. (760 aa)
	S100A2	Protein S100; Belongs to the S-100 family. (112 aa)
	RAB13	Uncharacterized protein. (203 aa)
	EDN2	Endothelin 2. (186 aa)
	EGR3	Early growth response 3. (387 aa)
	LOXL2	Lysyl oxidase like 2. (774 aa)
	STARD13	StAR related lipid transfer domain containing 13. (1123 aa)
	EPHB4	EPH receptor B4. (987 aa)
	CLN3	Battenin. (460 aa)
	LGALS12	Galectin. (275 aa)
	ADTRP	Androgen dependent TFPI regulating protein. (230 aa)
	PLXND1	Plexin D1. (1930 aa)
	CDH13	Cadherin 13. (713 aa)
	A0A4W2C190	Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (281 aa)
	PXN	Uncharacterized protein. (1066 aa)
	CCBE1	Collagen and calcium binding EGF domains 1. (408 aa)
	LPXN	Leupaxin. (399 aa)
	SRF	Serum response factor. (509 aa)
	TGFBR1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
	EFNB2	Ephrin B2; Belongs to the ephrin family. (342 aa)
	PLEKHG5	Pleckstrin homology and RhoGEF domain containing G5. (1143 aa)
	ABL1	Tyrosine-protein kinase. (1151 aa)
	SOX18	SRY-box transcription factor 18. (389 aa)
	NOS3	Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
	CCN3	Cellular communication network factor 3. (355 aa)
	CXCL13	C-X-C motif chemokine. (109 aa)
	KDR	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
	ROBO1	Roundabout guidance receptor 1. (1650 aa)

Your Current Organism:

Bos indicus

NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A4W2EQZ6	GIPC1	A0A4W2EQZ6	A0A4W2F289	Uncharacterized protein.	GIPC PDZ domain containing family member 1.	0.420
A0A4W2EQZ6	GIPC2	A0A4W2EQZ6	A0A4W2DNJ0	Uncharacterized protein.	GIPC PDZ domain containing family member 2.	0.420
A0A4W2EQZ6	PLXND1	A0A4W2EQZ6	A0A4W2BSC6	Uncharacterized protein.	Plexin D1.	0.471
ABL1	EPHB4	A0A4W2CTP7	A0A4W2BNK2	Tyrosine-protein kinase.	EPH receptor B4.	0.919
ABL1	ROBO1	A0A4W2CTP7	A0A4W2DG90	Tyrosine-protein kinase.	Roundabout guidance receptor 1.	0.913
ABL1	SLIT2	A0A4W2CTP7	A0A4W2G318	Tyrosine-protein kinase.	Slit guidance ligand 2.	0.550
AKT1	FGF2	A0A4W2FNQ0	A0A4W2EC73	Non-specific serine/threonine protein kinase.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.437
AKT1	NOS3	A0A4W2FNQ0	A0A4W2D4M9	Non-specific serine/threonine protein kinase.	Nitric oxide synthase; Produces nitric oxide (NO).	0.873
AKT1	NR4A1	A0A4W2FNQ0	A0A4W2G293	Non-specific serine/threonine protein kinase.	Nuclear receptor subfamily 4 group A member 1.	0.813
AKT1	PIK3R3	A0A4W2FNQ0	A0A4W2EXQ2	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.854
AKT1	RHOA	A0A4W2FNQ0	A0A4W2FLL1	Non-specific serine/threonine protein kinase.	Ras homolog family member A.	0.490
CCBE1	SOX18	A0A4W2CDK4	A0A4W2CV28	Collagen and calcium binding EGF domains 1.	SRY-box transcription factor 18.	0.491
CDH13	CDH5	A0A4W2BYQ0	A0A4W2E0P6	Cadherin 13.	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	0.418
CDH5	CDH13	A0A4W2E0P6	A0A4W2BYQ0	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	Cadherin 13.	0.418
CDH5	EFNB2	A0A4W2E0P6	A0A4W2CRE8	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	Ephrin B2; Belongs to the ephrin family.	0.461
CDH5	FGF2	A0A4W2E0P6	A0A4W2EC73	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.537
CDH5	ITGB1	A0A4W2E0P6	A0A4W2GGZ1	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	Integrin beta; Belongs to the integrin beta chain family.	0.519
CDH5	KDR	A0A4W2E0P6	A0A4W2D952	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.959
CDH5	MMRN2	A0A4W2E0P6	A0A4W2EPY9	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	Multimerin 2.	0.400
CDH5	NOS3	A0A4W2E0P6	A0A4W2D4M9	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	Nitric oxide synthase; Produces nitric oxide (NO).	0.466

page 1 of 8

Server load: low (14%) [HD]

Permalink

Network

Fusion

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Neighborhood

© STRING Consortium 2025

Credits

Access

Info

About