(32 nodes) Main axon network (Bos indicus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SPOCK1	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1. (439 aa)
	DAGLA	Diacylglycerol lipase alpha. (1041 aa)
	HAPLN2	Hyaluronan and proteoglycan link protein 2. (344 aa)
	ERMN	Ermin. (282 aa)
	SCN1A	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2009 aa)
	KCNAB1	Potassium voltage-gated channel subfamily A member regulatory beta subunit 1. (419 aa)
	TUBB4A	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
	C9orf72	C9orf72-SMCR8 complex subunit. (481 aa)
	MYOC	Myocilin. (490 aa)
	KCNAB2	Potassium voltage-gated channel subfamily A regulatory beta subunit 2. (414 aa)
	SLC1A2	Amino acid transporter. (595 aa)
	SPTBN1	Spectrin beta chain; Belongs to the spectrin family. (2350 aa)
	SPTBN4	Spectrin beta, non-erythrocytic 4. (2615 aa)
	KCNQ3	Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family. (865 aa)
	CNTNAP1	Contactin associated protein 1. (1362 aa)
	KCNA4	Potassium voltage-gated channel subfamily A member 4; Belongs to the potassium channel family. (661 aa)
	KCNA1	Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (495 aa)
	DAG1	Dystroglycan 1. (1096 aa)
	MBP	Uncharacterized protein. (497 aa)
	KCNQ2	Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family. (899 aa)
	DLG1	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa)
	TRIM46	Tripartite motif containing 46. (785 aa)
	MYO1D	Myosin ID; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1006 aa)
	KCNA2	Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family. (499 aa)
	KCNC1	Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family. (585 aa)
	CNTN2	Contactin 2. (1040 aa)
	MAG	Myelin associated glycoprotein. (678 aa)
	DLG4	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (754 aa)
	SCN1B	Sodium voltage-gated channel beta subunit 1. (218 aa)
	TNFRSF1B	Uncharacterized protein. (588 aa)
	NAV1	Neuron navigator 1. (2221 aa)
	UCN	Urocortin. (129 aa)

Your Current Organism:

Bos indicus

NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CNTN2	CNTNAP1	A0A4W2EK95	A0A4W2CH63	Contactin 2.	Contactin associated protein 1.	0.833
CNTNAP1	CNTN2	A0A4W2CH63	A0A4W2EK95	Contactin associated protein 1.	Contactin 2.	0.833
DLG1	DLG4	A0A4W2D0Z2	A0A4W2E5B6	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	0.952
DLG4	DLG1	A0A4W2E5B6	A0A4W2D0Z2	Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	0.952
ERMN	HAPLN2	A0A4W2EYR4	A0A4W2EZG9	Ermin.	Hyaluronan and proteoglycan link protein 2.	0.749
ERMN	MAG	A0A4W2EYR4	A0A4W2E303	Ermin.	Myelin associated glycoprotein.	0.516
ERMN	MBP	A0A4W2EYR4	A0A4W2BN03	Ermin.	Uncharacterized protein.	0.601
HAPLN2	ERMN	A0A4W2EZG9	A0A4W2EYR4	Hyaluronan and proteoglycan link protein 2.	Ermin.	0.749
KCNA1	KCNAB1	A0A4W2C508	A0A4W2EWC9	Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family.	Potassium voltage-gated channel subfamily A member regulatory beta subunit 1.	0.788
KCNA1	KCNAB2	A0A4W2C508	A0A4W2CRF9	Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family.	Potassium voltage-gated channel subfamily A regulatory beta subunit 2.	0.852
KCNA1	SCN1A	A0A4W2C508	A0A4W2EWH8	Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.611
KCNA2	KCNAB1	A0A4W2DMX4	A0A4W2EWC9	Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family.	Potassium voltage-gated channel subfamily A member regulatory beta subunit 1.	0.821
KCNA2	KCNAB2	A0A4W2DMX4	A0A4W2CRF9	Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family.	Potassium voltage-gated channel subfamily A regulatory beta subunit 2.	0.797
KCNA2	SCN1A	A0A4W2DMX4	A0A4W2EWH8	Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.443
KCNA4	KCNAB1	A0A4W2CE33	A0A4W2EWC9	Potassium voltage-gated channel subfamily A member 4; Belongs to the potassium channel family.	Potassium voltage-gated channel subfamily A member regulatory beta subunit 1.	0.757
KCNA4	KCNAB2	A0A4W2CE33	A0A4W2CRF9	Potassium voltage-gated channel subfamily A member 4; Belongs to the potassium channel family.	Potassium voltage-gated channel subfamily A regulatory beta subunit 2.	0.792
KCNAB1	KCNA1	A0A4W2EWC9	A0A4W2C508	Potassium voltage-gated channel subfamily A member regulatory beta subunit 1.	Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family.	0.788
KCNAB1	KCNA2	A0A4W2EWC9	A0A4W2DMX4	Potassium voltage-gated channel subfamily A member regulatory beta subunit 1.	Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family.	0.821
KCNAB1	KCNA4	A0A4W2EWC9	A0A4W2CE33	Potassium voltage-gated channel subfamily A member regulatory beta subunit 1.	Potassium voltage-gated channel subfamily A member 4; Belongs to the potassium channel family.	0.757
KCNAB1	KCNC1	A0A4W2EWC9	A0A4W2DUX9	Potassium voltage-gated channel subfamily A member regulatory beta subunit 1.	Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family.	0.697

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