STRINGSTRING
CHRM5 CHRM5 UTRN UTRN CNTN2 CNTN2 SYNJ2BP SYNJ2BP GRIK2 GRIK2 P2RX1 P2RX1 KCNH1 KCNH1 ATAD1 ATAD1 RGS9 RGS9 SNTA1 SNTA1 GRIN2D GRIN2D CACNG4 CACNG4 EPHA4 EPHA4 ADCY1 ADCY1 ATP2B2 ATP2B2 SYNDIG1 SYNDIG1 FLRT3 FLRT3 KPNA2 KPNA2 SLC6A6 SLC6A6 LHFPL4 LHFPL4 LIN7B LIN7B DLG4 DLG4 SHISA6 SHISA6 NLGN2 NLGN2 SCRIB SCRIB GRIN2C GRIN2C LIN7C LIN7C GABRB3 GABRB3 CBLN1 CBLN1 GABRA5 GABRA5 SHISA9 SHISA9 PTPRO PTPRO KCNMA1 KCNMA1 PCDH17 PCDH17 SHISA8 SHISA8 PRRT1 PRRT1 GSG1L GSG1L SORCS3 SORCS3 DNM2 DNM2 KCND3 KCND3 CACNG2 CACNG2 GRM5 GRM5 GRIN2A GRIN2A KCNB1 KCNB1 GRIN3A GRIN3A GLRA3 GLRA3 SIGMAR1 SIGMAR1 CHRM4 CHRM4 LIN7A LIN7A HTR3D HTR3D NSG1 NSG1 DLG1 DLG1 PLPPR4 PLPPR4 LRFN1 LRFN1 LRRC4 LRRC4 CLSTN1 CLSTN1 RGS7BP RGS7BP KCND2 KCND2 CHRNA4 CHRNA4 CLSTN3 CLSTN3 CRKL CRKL RAPSN RAPSN SHANK1 SHANK1 ADAM22 ADAM22 GABRD GABRD CHRNB4 CHRNB4 A0A4W2CJN8 A0A4W2CJN8 A0A4W2CJJ3 A0A4W2CJJ3 GABRR2 GABRR2 LRFN2 LRFN2 SHISA7 SHISA7 CACNG5 CACNG5 GRIA2 GRIA2 TRPV1 TRPV1 GABRP GABRP LRFN5 LRFN5 CHRNE CHRNE NPTX2 NPTX2 RPH3A RPH3A CHRNB1 CHRNB1 A0A4W2C6F2 A0A4W2C6F2 ZACN ZACN GABBR1 GABBR1 NRGN NRGN A0A4W2C3X9 A0A4W2C3X9 LOC113879687 LOC113879687 CHRNA5 CHRNA5 CACNA1C CACNA1C A0A4W2C159 A0A4W2C159 DRD2 DRD2 DCC DCC GRIK4 GRIK4 GRIN3B GRIN3B DBNL DBNL CSPG5 CSPG5 DAG1 DAG1 FXYD6 FXYD6 CDH2 CDH2 CHRNA6 CHRNA6 CTNNB1 CTNNB1 HIP1 HIP1 NLGN4X NLGN4X KCTD16 KCTD16 CHRNB2 CHRNB2 GLRA1 GLRA1 F2R F2R NLGN1 NLGN1 GABRB1 GABRB1 CHRNA2 CHRNA2 GPHN GPHN LOC113899002 LOC113899002 A0A4W2ESI2 A0A4W2ESI2 PDLIM4 PDLIM4 NPTN NPTN FAIM2 FAIM2 SLITRK3 SLITRK3 ABHD17A ABHD17A GRIK3 GRIK3 LRRTM2 LRRTM2 CLSTN2 CLSTN2 GRID2 GRID2 GRM3 GRM3 GABRA6 GABRA6 GABRB2 GABRB2 ADGRL2 ADGRL2 GABRR3 GABRR3 KCTD12 KCTD12 LRFN3 LRFN3 DAGLA DAGLA GRIN2B GRIN2B HSPA8 HSPA8 GABRA4 GABRA4 GABRG1 GABRG1 CHRNA9 CHRNA9 TMUB1 TMUB1 LRRC4B LRRC4B ABHD17C ABHD17C LRRC4C LRRC4C LRFN4 LRFN4 CACNG8 CACNG8 CACNG3 CACNG3 HTR3A HTR3A NETO1 NETO1 GABRA1 GABRA1 DBN1 DBN1 GABRG3 GABRG3 ERBB4 ERBB4 TRAPPC4 TRAPPC4 MPP2 MPP2 GRIK1 GRIK1 CHRNA1 CHRNA1 EPHB2 EPHB2 LOC113888622 LOC113888622 SRGAP2 SRGAP2 LRRTM1 LRRTM1 GABRA2 GABRA2 GLRB GLRB CHRND CHRND ATP6AP2 ATP6AP2 CHRM3 CHRM3 HTR3B HTR3B CACNG7 CACNG7 GRIA1 GRIA1 GRM1 GRM1 CNTN1 CNTN1 CHRNB3 CHRNB3 GABRG2 GABRG2 CHRM2 CHRM2 GRID1 GRID1 NRP2 NRP2 SLITRK1 SLITRK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CHRM5Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (532 aa)
UTRNUtrophin. (3432 aa)
CNTN2Contactin 2. (1040 aa)
SYNJ2BPSynaptojanin 2 binding protein. (145 aa)
GRIK2Glutamate ionotropic receptor kainate type subunit 2. (908 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
KCNH1Uncharacterized protein. (987 aa)
ATAD1ATPase family AAA domain containing 1; Belongs to the AAA ATPase family. (361 aa)
RGS9Regulator of G protein signaling 9. (639 aa)
SNTA1Syntrophin alpha 1. (505 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D. (1333 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (321 aa)
EPHA4EPH receptor A4. (949 aa)
ADCY1Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1197 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
SYNDIG1Synapse differentiation inducing 1. (264 aa)
FLRT3Fibronectin leucine rich transmembrane protein 3. (649 aa)
KPNA2Importin subunit alpha; Functions in nuclear protein import. (529 aa)
SLC6A6Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (874 aa)
LHFPL4LHFPL tetraspan subfamily member 4. (247 aa)
LIN7BProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (207 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (754 aa)
SHISA6Shisa family member 6. (552 aa)
NLGN2Neuroligin 2. (835 aa)
SCRIBScribble planar cell polarity protein. (1603 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C. (872 aa)
LIN7CProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (197 aa)
GABRB3Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (498 aa)
CBLN1Cerebellin 1 precursor. (193 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (462 aa)
SHISA9Shisa family member 9. (425 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1216 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1276 aa)
PCDH17Protocadherin 17. (1189 aa)
SHISA8Shisa family member 8. (401 aa)
PRRT1Proline rich transmembrane protein 1. (305 aa)
GSG1LGSG1 like. (376 aa)
SORCS3Sortilin related VPS10 domain containing receptor 3. (1222 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (880 aa)
KCND3Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (655 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (300 aa)
GRM5Glutamate metabotropic receptor 5. (1185 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1114 aa)
GLRA3Glycine receptor alpha 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (463 aa)
SIGMAR1Sigma non-opioid intracellular receptor 1. (267 aa)
CHRM4Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (541 aa)
LIN7AProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (233 aa)
HTR3D5-hydroxytryptamine receptor 3D; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (451 aa)
NSG1Neuronal vesicle trafficking associated 1. (218 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa)
PLPPR4Phospholipid phosphatase related 4. (763 aa)
LRFN1Leucine rich repeat and fibronectin type III domain containing 1. (835 aa)
LRRC4Leucine rich repeat containing 4. (652 aa)
CLSTN1Calsyntenin 1. (980 aa)
RGS7BPRegulator of G protein signaling 7 binding protein. (280 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (630 aa)
CHRNA4Cholinergic receptor nicotinic alpha 4 subunit. (612 aa)
CLSTN3Calsyntenin 3. (1049 aa)
CRKLCRK like proto-oncogene, adaptor protein. (302 aa)
RAPSNReceptor associated protein of the synapse. (427 aa)
SHANK1SH3 and multiple ankyrin repeat domains 1. (2179 aa)
ADAM22ADAM metallopeptidase domain 22. (974 aa)
GABRDGamma-aminobutyric acid type A receptor delta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (507 aa)
CHRNB4Cholinergic receptor nicotinic beta 4 subunit. (510 aa)
A0A4W2CJN8Uncharacterized protein. (450 aa)
A0A4W2CJJ3Uncharacterized protein. (457 aa)
GABRR2Gamma-aminobutyric acid type A receptor rho2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (484 aa)
LRFN2Leucine rich repeat and fibronectin type III domain containing 2. (786 aa)
SHISA7Shisa family member 7. (612 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (424 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (837 aa)
GABRPGamma-aminobutyric acid type A receptor pi subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (440 aa)
LRFN5Leucine rich repeat and fibronectin type III domain containing 5. (717 aa)
CHRNECholinergic receptor nicotinic epsilon subunit. (493 aa)
NPTX2Neuronal pentraxin 2. (431 aa)
RPH3ARabphilin 3A. (704 aa)
CHRNB1Cholinergic receptor nicotinic beta 1 subunit. (505 aa)
A0A4W2C6F2Sushi domain-containing protein. (231 aa)
ZACNZinc activated ion channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (410 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (843 aa)
NRGNNeurogranin. (78 aa)
A0A4W2C3X9ANF_receptor domain-containing protein. (179 aa)
LOC113879687Uncharacterized protein. (514 aa)
CHRNA5Cholinergic receptor nicotinic alpha 5 subunit. (475 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2194 aa)
A0A4W2C159Chon_Sulph_att domain-containing protein. (419 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
DCCDCC netrin 1 receptor. (1490 aa)
GRIK4Glutamate ionotropic receptor kainate type subunit 4. (957 aa)
GRIN3BGlutamate ionotropic receptor NMDA type subunit 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1028 aa)
DBNLDrebrin like. (503 aa)
CSPG5Chondroitin sulfate proteoglycan 5. (538 aa)
DAG1Dystroglycan 1. (1096 aa)
FXYD6FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (95 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (1318 aa)
CHRNA6Cholinergic receptor nicotinic alpha 6 subunit. (494 aa)
CTNNB1Catenin beta 1. (774 aa)
HIP1Huntingtin interacting protein 1. (1037 aa)
NLGN4XCOesterase domain-containing protein. (856 aa)
KCTD16Potassium channel tetramerization domain containing 16. (428 aa)
CHRNB2Cholinergic receptor nicotinic beta 2 subunit. (503 aa)
GLRA1Glycine receptor alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (457 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (427 aa)
NLGN1Neuroligin 1. (823 aa)
GABRB1Gamma-aminobutyric acid type A receptor beta1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)
CHRNA2Cholinergic receptor nicotinic alpha 2 subunit. (506 aa)
GPHNGephyrin. (839 aa)
LOC113899002Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (463 aa)
A0A4W2ESI2Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (466 aa)
PDLIM4PDZ and LIM domain 4. (311 aa)
NPTNNeuroplastin. (471 aa)
FAIM2Fas apoptotic inhibitory molecule 2. (449 aa)
SLITRK3SLIT and NTRK like family member 3. (980 aa)
ABHD17AAbhydrolase domain containing 17A. (310 aa)
GRIK3Glutamate ionotropic receptor kainate type subunit 3. (919 aa)
LRRTM2Leucine rich repeat transmembrane neuronal 2. (516 aa)
CLSTN2Calsyntenin 2. (955 aa)
GRID2Glutamate ionotropic receptor delta type subunit 2. (1007 aa)
GRM3Glutamate metabotropic receptor 3. (879 aa)
GABRA6Gamma-aminobutyric acid type A receptor alpha6 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (453 aa)
GABRB2Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (512 aa)
ADGRL2Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family. (1483 aa)
GABRR3Gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene); Belongs to the ligand-gated ion channel (TC 1.A.9) family. (468 aa)
KCTD12Potassium channel tetramerization domain containing 12. (326 aa)
LRFN3Leucine rich repeat and fibronectin type III domain containing 3. (628 aa)
DAGLADiacylglycerol lipase alpha. (1041 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1497 aa)
HSPA8Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family. (650 aa)
GABRA4Gamma-aminobutyric acid type A receptor alpha4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (555 aa)
GABRG1Gamma-aminobutyric acid type A receptor gamma1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (465 aa)
CHRNA9Cholinergic receptor nicotinic alpha 9 subunit. (479 aa)
TMUB1Transmembrane and ubiquitin like domain containing 1. (246 aa)
LRRC4BLeucine rich repeat containing 4B. (715 aa)
ABHD17CAbhydrolase domain containing 17C. (365 aa)
LRRC4CLeucine rich repeat containing 4C. (640 aa)
LRFN4Leucine rich repeat and fibronectin type III domain containing 4. (748 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (426 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
HTR3A5-hydroxytryptamine receptor 3A; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (490 aa)
NETO1Neuropilin and tolloid like 1. (533 aa)
GABRA1Gamma-aminobutyric acid type A receptor alpha1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (471 aa)
DBN1Drebrin 1. (726 aa)
GABRG3Gamma-aminobutyric acid type A receptor gamma3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (467 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
TRAPPC4Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (219 aa)
MPP2Membrane palmitoylated protein 2; Belongs to the MAGUK family. (569 aa)
GRIK1Glutamate ionotropic receptor kainate type subunit 1. (949 aa)
CHRNA1Cholinergic receptor nicotinic alpha 1 subunit. (475 aa)
EPHB2EPH receptor B2. (986 aa)
LOC113888622Abhydrolase domain containing 6. (337 aa)
SRGAP2Uncharacterized protein. (1084 aa)
LRRTM1Leucine rich repeat transmembrane neuronal 1. (521 aa)
GABRA2Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (511 aa)
GLRBGlycine receptor beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (497 aa)
CHRNDCholinergic receptor nicotinic delta subunit. (567 aa)
ATP6AP2Uncharacterized protein. (377 aa)
CHRM3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (602 aa)
HTR3B5-hydroxytryptamine receptor 3B; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (436 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (906 aa)
GRM1Glutamate metabotropic receptor 1. (1192 aa)
CNTN1Contactin 1. (1018 aa)
CHRNB3Cholinergic receptor nicotinic beta 3 subunit. (458 aa)
GABRG2Gamma-aminobutyric acid type A receptor gamma2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (475 aa)
CHRM2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (465 aa)
GRID1Glutamate ionotropic receptor delta type subunit 1. (1009 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (931 aa)
SLITRK1SLIT and NTRK like family member 1. (696 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
Server load: low (28%) [HD]