STRINGSTRING
TTK TTK WAC WAC CDC6 CDC6 ATF5 ATF5 CDKN2D CDKN2D HPGD HPGD HINFP HINFP CHMP2A CHMP2A ZFP36L2 ZFP36L2 MOS MOS E2F8 E2F8 CDK1 CDK1 TP53 TP53 RB1 RB1 A0A4W2HUR1 A0A4W2HUR1 TRIM39 TRIM39 CDKN2C CDKN2C CDKN1B CDKN1B BAZ1B BAZ1B NACC2 NACC2 DACT1 DACT1 E2F1 E2F1 BABAM2 BABAM2 CDK5RAP1 CDK5RAP1 KANK2 KANK2 PHKG1 PHKG1 PTPN11 PTPN11 HHEX HHEX TAOK2 TAOK2 CDKN2B CDKN2B CDKN1C CDKN1C NEK2 NEK2 TRIM35 TRIM35 HEXIM2 HEXIM2 TAOK3 TAOK3 NUPR1 NUPR1 LOC113899187 LOC113899187 NR2F2 NR2F2 ZW10 ZW10 CTDSPL CTDSPL MSH2 MSH2 NAE1 NAE1 DNA2 DNA2 OVOL1 OVOL1 RAD21 RAD21 NR4A1 NR4A1 MEN1 MEN1 CHFR CHFR TIMELESS TIMELESS BMP2 BMP2 APBB2 APBB2 CDK6 CDK6 RBL1 RBL1 TNKS TNKS INIP INIP PLK3 PLK3 TFAP4 TFAP4 INTS3 INTS3 GML GML NABP2 NABP2 KAT2B KAT2B A0A4W2F400 A0A4W2F400 RINT1 RINT1 FBXO7 FBXO7 TOPBP1 TOPBP1 A0A4W2EYN7 A0A4W2EYN7 A0A4W2EYF1 A0A4W2EYF1 BABAM1 BABAM1 GPNMB GPNMB CLSPN CLSPN SYF2 SYF2 A0A4W2EVL2 A0A4W2EVL2 A0A4W2EUZ6 A0A4W2EUZ6 ABRAXAS1 ABRAXAS1 E2F7 E2F7 UIMC1 UIMC1 GAS1 GAS1 TIPIN TIPIN A0A4W2ET95 A0A4W2ET95 A0A4W2ES96 A0A4W2ES96 A0A4W2ERQ5 A0A4W2ERQ5 GMNC GMNC RPS6KA2 RPS6KA2 FZD3 FZD3 AVEN AVEN BUB1B BUB1B TENT5B TENT5B MDM1 MDM1 RPS27L RPS27L MIIP MIIP RAD17 RAD17 RAD9B RAD9B CTDSP2 CTDSP2 BRD7 BRD7 HUS1 HUS1 CDT1 CDT1 BMP4 BMP4 TNF TNF CDKN1A CDKN1A TNFAIP3 TNFAIP3 DAB2IP DAB2IP CDC5L CDC5L HECA HECA BRCA1 BRCA1 CCND1 CCND1 PML PML EEF1AKNMT EEF1AKNMT A0A4W2E9V0 A0A4W2E9V0 MCIDAS MCIDAS KNTC1 KNTC1 HEXIM1 HEXIM1 VPS4A VPS4A KLHL22 KLHL22 USP47 USP47 AURKB AURKB INCA1 INCA1 DLG2 DLG2 TP53I13 TP53I13 CHEK2 CHEK2 BIRC5 BIRC5 SCRIB SCRIB BRINP3 BRINP3 KAT2A KAT2A A0A4W2E2U3 A0A4W2E2U3 EME1 EME1 TIPRL TIPRL SMARCA5 SMARCA5 A0A4W2DZY8 A0A4W2DZY8 NEK11 NEK11 TP53BP1 TP53BP1 TPR TPR BLM BLM MAD1L1 MAD1L1 GPER1 GPER1 ANGEL2 ANGEL2 A0A4W2DXK0 A0A4W2DXK0 DTL DTL GMNN GMNN A0A4W2DWY9 A0A4W2DWY9 RAD9A RAD9A H2AFY H2AFY BUB3 BUB3 NLE1 NLE1 FANCD2 FANCD2 CCL2 CCL2 FOXO4 FOXO4 LRRC1 LRRC1 MAP3K20 MAP3K20 ATM ATM SIRT1 SIRT1 MAD2L1BP MAD2L1BP NUPR2 NUPR2 CHEK1 CHEK1 CDK2AP2 CDK2AP2 TOM1L1 TOM1L1 ZNF655 ZNF655 TEX14 TEX14 TRIM37 TRIM37 TPRA1 TPRA1 PRPF19 PRPF19 ZNF207 ZNF207 TAOK1 TAOK1 BTG3 BTG3 ORC1 ORC1 DONSON DONSON MAD2L1 MAD2L1 IK IK ATR ATR BUB1 BUB1 PTTG1 PTTG1 CDKN2A CDKN2A PKD2 PKD2 A0A4W2DCT4 A0A4W2DCT4 BMP7 BMP7 A0A4W2D9V3 A0A4W2D9V3 CDK5 CDK5 LOC113896623 LOC113896623 CLOCK CLOCK ZFP36L1 ZFP36L1 NKX3-1 NKX3-1 CASP2 CASP2 ATF2 ATF2 HORMAD1 HORMAD1 IZUMO4 IZUMO4 DOT1L DOT1L WAPL WAPL EZH2 EZH2 CDK5RAP2 CDK5RAP2 A0A4W2D3H6 A0A4W2D3H6 CRADD CRADD PTPN3 PTPN3 FZR1 FZR1 PTPRK PTPRK DLG1 DLG1 ERCC6 ERCC6 WEE2 WEE2 BRINP1 BRINP1 PINX1 PINX1 DMRT1 DMRT1 GATA3 GATA3 CDC73 CDC73 EIF2AK4 EIF2AK4 FBXO5 FBXO5 ZFYVE19 ZFYVE19 A0A4W2CV54 A0A4W2CV54 LATS1 LATS1 A0A4W2CUT9 A0A4W2CUT9 EPM2A EPM2A ABL1 ABL1 TMEM67 TMEM67 A0A4W2CT96 A0A4W2CT96 SDE2 SDE2 FBXO43 FBXO43 INHBA INHBA SUSD2 SUSD2 NPR2 NPR2 RGS22 RGS22 CTDSP1 CTDSP1 A0A4W2CLZ8 A0A4W2CLZ8 A0A4W2CLZ1 A0A4W2CLZ1 RRP8 RRP8 BTG2 BTG2 NANOS2 NANOS2 THAP5 THAP5 STK33 STK33 TGFB1 TGFB1 TRIP13 TRIP13 NOP53 NOP53 NSUN2 NSUN2 PRKDC PRKDC MEIOC MEIOC RAD1 RAD1 MTBP MTBP CHMP4C CHMP4C MAPK12 MAPK12 A0A4W2CDR2 A0A4W2CDR2 A0A4W2CDI7 A0A4W2CDI7 A0A4W2CCW8 A0A4W2CCW8 A0A4W2CC63 A0A4W2CC63 SPDL1 SPDL1 RNF167 RNF167 RBL2 RBL2 NBN NBN APC APC HASPIN HASPIN ALOX15B ALOX15B BRINP2 BRINP2 INTS7 INTS7 TICRR TICRR LIF LIF FBXO31 FBXO31 PPP1R10 PPP1R10 PPP1R13B PPP1R13B RHNO1 RHNO1 SLC9A3R1 SLC9A3R1 C10orf90 C10orf90 MFSD11 MFSD11 GPR132 GPR132 MYOCD MYOCD A0A4W2C3D5 A0A4W2C3D5 TAF6 TAF6 TOM1L2 TOM1L2 CASP3 CASP3 JADE1 JADE1 A0A4W2C0C3 A0A4W2C0C3 A0A4W2BZY5 A0A4W2BZY5 MRE11 MRE11 CDK5RAP3 CDK5RAP3 USP28 USP28 RFWD3 RFWD3 NME6 NME6 CCP110 CCP110 RBM14 RBM14 BTG4 BTG4 BCL2 BCL2 NUDT6 NUDT6 DCUN1D3 DCUN1D3 MUS81 MUS81 PSMG2 PSMG2 ATRIP ATRIP CCDC84 CCDC84 ZNF830 ZNF830 CRLF3 CRLF3 PIDD1 PIDD1 PLK1 PLK1 XPC XPC SUV39H1 SUV39H1 CTNNB1 CTNNB1 CCNF CCNF A0A4W2BP37 A0A4W2BP37 A0A4W2BNU5 A0A4W2BNU5 LATS2 LATS2 NUBP1 NUBP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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TTKTTK protein kinase. (924 aa)
WACWW domain containing adaptor with coiled-coil. (646 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (607 aa)
ATF5Activating transcription factor 5. (281 aa)
CDKN2DCyclin dependent kinase inhibitor 2D. (166 aa)
HPGD15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa)
HINFPHistone H4 transcription factor. (516 aa)
CHMP2ACharged multivesicular body protein 2A. (222 aa)
ZFP36L2ZFP36 ring finger protein like 2. (485 aa)
MOSMOS proto-oncogene, serine/threonine kinase; Belongs to the protein kinase superfamily. (340 aa)
E2F8E2F transcription factor 8. (868 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (499 aa)
RB1RB transcriptional corepressor 1. (928 aa)
A0A4W2HUR1HORMA domain-containing protein. (197 aa)
TRIM39Tripartite motif containing 39. (488 aa)
CDKN2CCyclin dependent kinase inhibitor 2C. (168 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
BAZ1BBromodomain adjacent to zinc finger domain 1B. (1482 aa)
NACC2NACC family member 2. (585 aa)
DACT1Dishevelled binding antagonist of beta catenin 1. (837 aa)
E2F1E2F transcription factor 1. (437 aa)
BABAM2BRISC and BRCA1 A complex member 2. (383 aa)
CDK5RAP1CDK5 regulatory subunit associated protein 1. (603 aa)
KANK2KN motif and ankyrin repeat domains 2. (858 aa)
PHKG1Phosphorylase kinase catalytic subunit gamma 1; Belongs to the protein kinase superfamily. (387 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
HHEXHematopoietically expressed homeobox. (271 aa)
TAOK2TAO kinase 2. (1125 aa)
CDKN2BCyclin dependent kinase inhibitor 2B. (138 aa)
CDKN1CUncharacterized protein. (438 aa)
NEK2NIMA related kinase 2. (445 aa)
TRIM35Tripartite motif containing 35. (493 aa)
HEXIM2HEXIM P-TEFb complex subunit 2. (288 aa)
TAOK3TAO kinase 3. (898 aa)
NUPR1Nuclear protein 1, transcriptional regulator. (82 aa)
LOC113899187Uncharacterized protein. (202 aa)
NR2F2Nuclear receptor subfamily 2 group F member 2. (414 aa)
ZW10Zw10 kinetochore protein. (779 aa)
CTDSPLCTD small phosphatase like. (276 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa)
NAE1NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. (541 aa)
DNA2DNA replication helicase/nuclease 2. (1061 aa)
OVOL1Ovo like transcriptional repressor 1. (267 aa)
RAD21RAD21 cohesin complex component. (630 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (598 aa)
MEN1Menin 1. (610 aa)
CHFRCheckpoint with forkhead and ring finger domains. (738 aa)
TIMELESSTimeless circadian regulator. (1213 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
APBB2Amyloid beta precursor protein binding family B member 2. (757 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
RBL1RB transcriptional corepressor like 1. (1068 aa)
TNKSPoly [ADP-ribose] polymerase. (1339 aa)
INIPINTS3 and NABP interacting protein. (104 aa)
PLK3Serine/threonine-protein kinase PLK. (647 aa)
TFAP4Transcription factor AP-4. (335 aa)
INTS3Integrator complex subunit 3. (1040 aa)
GMLUPAR/Ly6 domain-containing protein. (155 aa)
NABP2Nucleic acid binding protein 2. (211 aa)
KAT2BLysine acetyltransferase 2B. (990 aa)
A0A4W2F400Uncharacterized protein. (410 aa)
RINT1RAD50 interactor 1. (792 aa)
FBXO7F-box protein 7. (522 aa)
TOPBP1DNA topoisomerase II binding protein 1. (1521 aa)
A0A4W2EYN7SEA domain-containing protein. (663 aa)
A0A4W2EYF1Reverse transcriptase domain-containing protein. (738 aa)
BABAM1BRISC and BRCA1 A complex member 1. (332 aa)
GPNMBGlycoprotein nmb. (555 aa)
CLSPNClaspin. (1338 aa)
SYF2SYF2 pre-mRNA splicing factor. (245 aa)
A0A4W2EVL2Serine/threonine-protein kinase PLK. (548 aa)
A0A4W2EUZ6RING-type domain-containing protein. (58 aa)
ABRAXAS1Abraxas 1, BRCA1 A complex subunit. (421 aa)
E2F7E2F transcription factor 7. (912 aa)
UIMC1Ubiquitin interaction motif containing 1. (753 aa)
GAS1Growth arrest specific 1. (578 aa)
TIPINTIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (303 aa)
A0A4W2ET95Uncharacterized protein. (589 aa)
A0A4W2ES96Uncharacterized protein. (403 aa)
A0A4W2ERQ5Reverse transcriptase domain-containing protein. (1152 aa)
GMNCGeminin coiled-coil domain containing. (335 aa)
RPS6KA2Ribosomal protein S6 kinase. (759 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
AVENApoptosis and caspase activation inhibitor. (389 aa)
BUB1BUncharacterized protein. (1062 aa)
TENT5BTerminal nucleotidyltransferase 5B. (430 aa)
MDM1Mdm1 nuclear protein. (724 aa)
RPS27L40S ribosomal protein S27. (102 aa)
MIIPMigration and invasion inhibitory protein. (396 aa)
RAD17RAD17 checkpoint clamp loader component. (708 aa)
RAD9BCell cycle checkpoint control protein; Belongs to the rad9 family. (417 aa)
CTDSP2CTD small phosphatase 2. (271 aa)
BRD7Bromodomain containing 7. (853 aa)
HUS1Checkpoint protein; Belongs to the HUS1 family. (280 aa)
CDT1Chromatin licensing and DNA replication factor 1. (600 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (333 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (161 aa)
TNFAIP3TNF alpha induced protein 3. (780 aa)
DAB2IPDAB2 interacting protein. (1267 aa)
CDC5LCell division cycle 5 like. (802 aa)
HECAHdc homolog, cell cycle regulator. (543 aa)
BRCA1BRCA1 DNA repair associated. (1941 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (428 aa)
PMLPromyelocytic leukemia. (871 aa)
EEF1AKNMTEEF1A lysine and N-terminal methyltransferase. (699 aa)
A0A4W2E9V0RING-type domain-containing protein. (325 aa)
MCIDASMulticiliate differentiation and DNA synthesis associated cell cycle protein. (374 aa)
KNTC1Kinetochore associated 1. (2205 aa)
HEXIM1HEXIM P-TEFb complex subunit 1. (242 aa)
VPS4AUncharacterized protein; Belongs to the AAA ATPase family. (437 aa)
KLHL22Kelch like family member 22. (634 aa)
USP47Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1374 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (406 aa)
INCA1Inhibitor of CDK, cyclin A1 interacting protein 1. (233 aa)
DLG2Discs large MAGUK scaffold protein 2. (1009 aa)
TP53I13Tumor protein p53 inducible protein 13. (507 aa)
CHEK2Checkpoint kinase 2. (534 aa)
BIRC5Baculoviral IAP repeat containing 5. (142 aa)
SCRIBScribble planar cell polarity protein. (1603 aa)
BRINP3BMP/retinoic acid inducible neural specific 3. (766 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
A0A4W2E2U3ANK_REP_REGION domain-containing protein. (272 aa)
EME1Essential meiotic structure-specific endonuclease 1. (574 aa)
TIPRLTOR signaling pathway regulator. (364 aa)
SMARCA5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (1051 aa)
A0A4W2DZY8MOEP19 domain-containing protein. (598 aa)
NEK11NIMA related kinase 11. (634 aa)
TP53BP1Tumor protein p53 binding protein 1. (1966 aa)
TPRTranslocated promoter region, nuclear basket protein. (2444 aa)
BLMBLM RecQ like helicase. (1430 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (768 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
ANGEL2Angel homolog 2. (544 aa)
A0A4W2DXK0HORMA domain-containing protein. (258 aa)
DTLDenticleless E3 ubiquitin protein ligase homolog. (730 aa)
GMNNGeminin DNA replication inhibitor. (186 aa)
A0A4W2DWY9UPAR/Ly6 domain-containing protein. (155 aa)
RAD9ACell cycle checkpoint control protein; Belongs to the rad9 family. (422 aa)
H2AFYH2A histone family member Y. (412 aa)
BUB3BUB3 mitotic checkpoint protein. (343 aa)
NLE1Notchless homolog 1. (488 aa)
FANCD2FA complementation group D2. (1446 aa)
CCL2C-C motif chemokine. (99 aa)
FOXO4Forkhead box O4. (511 aa)
LRRC1Leucine rich repeat containing 1. (762 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (800 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3054 aa)
SIRT1Sirtuin 1. (734 aa)
MAD2L1BPMAD2L1 binding protein. (282 aa)
NUPR2Nuclear protein 2, transcriptional regulator. (98 aa)
CHEK1Checkpoint kinase 1. (677 aa)
CDK2AP2Cyclin-dependent kinase 2-associated protein; Belongs to the CDK2AP family. (127 aa)
TOM1L1Target of myb1 like 1 membrane trafficking protein; Belongs to the TOM1 family. (476 aa)
ZNF655Zinc finger protein 655. (543 aa)
TEX14Testis expressed 14, intercellular bridge forming factor. (1538 aa)
TRIM37Tripartite motif containing 37. (961 aa)
TPRA1Transmembrane protein adipocyte associated 1. (406 aa)
PRPF19Pre-mRNA processing factor 19. (504 aa)
ZNF207Zinc finger protein 207. (493 aa)
TAOK1TAO kinase 1. (1001 aa)
BTG3BTG anti-proliferation factor 3. (252 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (859 aa)
DONSONDownstream neighbor of SON. (620 aa)
MAD2L1HORMA domain-containing protein. (215 aa)
IKIK cytokine. (555 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa)
BUB1BUB1 mitotic checkpoint serine/threonine kinase. (1081 aa)
PTTG1Uncharacterized protein. (202 aa)
CDKN2ACyclin dependent kinase inhibitor 2A. (160 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (1071 aa)
A0A4W2DCT4Uncharacterized protein. (194 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
A0A4W2D9V3Reverse transcriptase domain-containing protein. (738 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
LOC113896623Uncharacterized protein. (202 aa)
CLOCKClock circadian regulator. (844 aa)
ZFP36L1ZFP36 ring finger protein like 1. (323 aa)
NKX3-1NK3 homeobox 1. (239 aa)
CASP2Caspase 2; Belongs to the peptidase C14A family. (452 aa)
ATF2Activating transcription factor 2. (447 aa)
HORMAD1HORMA domain containing 1. (392 aa)
IZUMO4IZUMO family member 4. (213 aa)
DOT1LHistone-lysine N-methyltransferase, H3 lysine-79 specific. (1890 aa)
WAPLWAPL cohesin release factor. (1208 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (779 aa)
CDK5RAP2CDK5 regulatory subunit associated protein 2. (1820 aa)
A0A4W2D3H6Fork-head domain-containing protein. (457 aa)
CRADDCASP2 and RIPK1 domain containing adaptor with death domain. (287 aa)
PTPN3Protein tyrosine phosphatase non-receptor type 3. (1056 aa)
FZR1Fizzy and cell division cycle 20 related 1. (523 aa)
PTPRKProtein tyrosine phosphatase receptor type K. (1471 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1544 aa)
WEE2Wee1-like protein kinase. (566 aa)
BRINP1BMP/retinoic acid inducible neural specific 1. (761 aa)
PINX1PIN2 (TERF1) interacting telomerase inhibitor 1. (309 aa)
DMRT1Doublesex and mab-3 related transcription factor 1. (355 aa)
GATA3GATA binding protein 3. (467 aa)
CDC73Cell division cycle 73. (531 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1660 aa)
FBXO5F-box protein 5. (448 aa)
ZFYVE19Zinc finger FYVE-type containing 19. (451 aa)
A0A4W2CV54Reverse transcriptase domain-containing protein. (798 aa)
LATS1Large tumor suppressor kinase 1. (1123 aa)
A0A4W2CUT9Uncharacterized protein. (277 aa)
EPM2AEPM2A glucan phosphatase, laforin. (331 aa)
ABL1Tyrosine-protein kinase. (1151 aa)
TMEM67Transmembrane protein 67. (996 aa)
A0A4W2CT96Reverse transcriptase domain-containing protein. (1169 aa)
SDE2SDE2 telomere maintenance homolog. (453 aa)
FBXO43F-box protein 43. (690 aa)
INHBAInhibin subunit beta A. (425 aa)
SUSD2Sushi domain containing 2. (821 aa)
NPR2Guanylate cyclase. (1041 aa)
RGS22Regulator of G protein signaling 22. (1254 aa)
CTDSP1CTD small phosphatase 1. (283 aa)
A0A4W2CLZ8Fork-head domain-containing protein. (225 aa)
A0A4W2CLZ1Reverse transcriptase domain-containing protein. (704 aa)
RRP8Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (460 aa)
BTG2BTG anti-proliferation factor 2. (150 aa)
NANOS2Nanos C2HC-type zinc finger 2; Belongs to the nanos family. (138 aa)
THAP5THAP domain containing 5. (395 aa)
STK33Serine/threonine kinase 33. (517 aa)
TGFB1Transforming growth factor beta 1. (443 aa)
TRIP13Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (436 aa)
NOP53NOP53 ribosome biogenesis factor. (534 aa)
NSUN2NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (806 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4122 aa)
MEIOCMeiosis specific with coiled-coil domain. (960 aa)
RAD1RAD1 checkpoint DNA exonuclease. (279 aa)
MTBPMDM2 binding protein. (898 aa)
CHMP4CCharged multivesicular body protein 4C. (236 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
A0A4W2CDR2Reverse transcriptase domain-containing protein. (738 aa)
A0A4W2CDI7Uncharacterized protein. (148 aa)
A0A4W2CCW8Reverse transcriptase domain-containing protein. (1148 aa)
A0A4W2CC63Fibronectin type-III domain-containing protein. (399 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (620 aa)
RNF167RING-type domain-containing protein. (349 aa)
RBL2RB transcriptional corepressor like 2. (1140 aa)
NBNNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (809 aa)
APCAPC regulator of WNT signaling pathway. (2912 aa)
HASPINHistone H3 associated protein kinase. (781 aa)
ALOX15BArachidonate 15-lipoxygenase type B. (677 aa)
BRINP2BMP/retinoic acid inducible neural specific 2. (784 aa)
INTS7Integrator complex subunit 7. (962 aa)
TICRRTOPBP1 interacting checkpoint and replication regulator. (1902 aa)
LIFLIF interleukin 6 family cytokine. (202 aa)
FBXO31F-box protein 31. (558 aa)
PPP1R10Protein phosphatase 1 regulatory subunit 10. (924 aa)
PPP1R13BProtein phosphatase 1 regulatory subunit 13B. (1136 aa)
RHNO1RAD9-HUS1-RAD1 interacting nuclear orphan 1. (241 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (368 aa)
C10orf90Chromosome 10 open reading frame 90. (794 aa)
MFSD11Major facilitator superfamily domain containing 11. (449 aa)
GPR132G protein-coupled receptor 132; Belongs to the G-protein coupled receptor 1 family. (372 aa)
MYOCDMyocardin. (981 aa)
A0A4W2C3D5Uncharacterized protein. (223 aa)
TAF6TATA-box binding protein associated factor 6. (740 aa)
TOM1L2Target of myb1 like 2 membrane trafficking protein; Belongs to the TOM1 family. (532 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
JADE1Jade family PHD finger 1. (872 aa)
A0A4W2C0C340S ribosomal protein S27. (95 aa)
A0A4W2BZY5Reverse transcriptase domain-containing protein. (738 aa)
MRE11MRE11 homolog, double strand break repair nuclease; Belongs to the MRE11/RAD32 family. (943 aa)
CDK5RAP3CDK5 regulatory subunit associated protein 3. (505 aa)
USP28Ubiquitin specific peptidase 28; Belongs to the peptidase C19 family. (1143 aa)
RFWD3Ring finger and WD repeat domain 3. (790 aa)
NME6Nucleoside diphosphate kinase. (186 aa)
CCP110Centriolar coiled-coil protein 110. (1006 aa)
RBM14RNA binding motif protein 14. (669 aa)
BTG4BTG anti-proliferation factor 4. (229 aa)
BCL2BCL2 apoptosis regulator. (229 aa)
NUDT6Nudix hydrolase 6; Belongs to the Nudix hydrolase family. (316 aa)
DCUN1D3DCN1-like protein. (304 aa)
MUS81MUS81 structure-specific endonuclease subunit. (552 aa)
PSMG2Proteasome assembly chaperone 2; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. Belongs to the PSMG2 family. (264 aa)
ATRIPATR interacting protein. (789 aa)
CCDC84Coiled-coil domain containing 84. (384 aa)
ZNF830Zinc finger protein 830. (373 aa)
CRLF3Fibronectin type-III domain-containing protein. (441 aa)
PIDD1P53-induced death domain protein 1. (946 aa)
PLK1Serine/threonine-protein kinase PLK. (602 aa)
XPCXPC complex subunit, DNA damage recognition and repair factor. (932 aa)
SUV39H1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (411 aa)
CTNNB1Catenin beta 1. (774 aa)
CCNFCyclin F; Belongs to the cyclin family. (479 aa)
A0A4W2BP37Uncharacterized protein. (74 aa)
A0A4W2BNU5Reverse transcriptase domain-containing protein. (1128 aa)
LATS2Large tumor suppressor kinase 2. (1015 aa)
NUBP1Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (385 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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