STRINGSTRING
TNFSF15 TNFSF15 RNF180 RNF180 ZYG11B ZYG11B LOC113891379 LOC113891379 DDA1 DDA1 CSNK1D CSNK1D SNCA SNCA PSMC5 PSMC5 PSMC3 PSMC3 APH1B APH1B NUPR1 NUPR1 ADRA2A ADRA2A A0A4W2DST9 A0A4W2DST9 SIRT1 SIRT1 UBQLN1 UBQLN1 DAPK1 DAPK1 SMURF1 SMURF1 A0A4W2DPJ5 A0A4W2DPJ5 SYK SYK A0A4W2DN34 A0A4W2DN34 NEK5 NEK5 TRIB2 TRIB2 WDR48 WDR48 RCHY1 RCHY1 CLEC3B CLEC3B PRELID1 PRELID1 RNFT2 RNFT2 PRICKLE1 PRICKLE1 BBC3 BBC3 SMAD7 SMAD7 MKRN2 MKRN2 ANGPTL8 ANGPTL8 PSME3 PSME3 RNF139 RNF139 BAX BAX STUB1 STUB1 CIDEB CIDEB FBXW7 FBXW7 SOX7 SOX7 MYC MYC RCN3 RCN3 IL1B IL1B NKD2 NKD2 CNTN2 CNTN2 AXIN1 AXIN1 NLRP6 NLRP6 GRAMD4 GRAMD4 DDX3X DDX3X SIRT6 SIRT6 CLDN3 CLDN3 PRSS22 PRSS22 BBS7 BBS7 GSN GSN KCNE2 KCNE2 TRIB3 TRIB3 SOCS5 SOCS5 RAD23A RAD23A PLGRKT PLGRKT USP13 USP13 DIABLO DIABLO ZYG11A ZYG11A WDR20 WDR20 LCK LCK WNT3A WNT3A FBXO22 FBXO22 CLDN4 CLDN4 MTCH1 MTCH1 RNF217 RNF217 ATP5IF1 ATP5IF1 HDAC2 HDAC2 CDC20 CDC20 PRR7 PRR7 SFRP2 SFRP2 CLUL1 CLUL1 ACVR1C ACVR1C GBA GBA VSIR VSIR SART3 SART3 GPER1 GPER1 GPLD1 GPLD1 TMEM259 TMEM259 FBXW8 FBXW8 COP1 COP1 OSBPL7 OSBPL7 A0A4W2E2B7 A0A4W2E2B7 RNF185 RNF185 TBC1D10A TBC1D10A HPN HPN SIRT2 SIRT2 GSK3A GSK3A A0A4W2E5D6 A0A4W2E5D6 RNF144B RNF144B DMWD DMWD CDC20B CDC20B FN1 FN1 NLRP1 NLRP1 STAT3 STAT3 ANP32B ANP32B EPHA4 EPHA4 FASLG FASLG CARD9 CARD9 PML PML VCP VCP TNFRSF1B TNFRSF1B GRN GRN DAB2IP DAB2IP TRIB1 TRIB1 LYN LYN TNF TNF DNAJB2 DNAJB2 HTRA2 HTRA2 IFNG IFNG USP50 USP50 P2RX1 P2RX1 EGLN3 EGLN3 ROBO1 ROBO1 NCSTN NCSTN SH3RF2 SH3RF2 RNF144A RNF144A FOXL2 FOXL2 REST REST AURKA AURKA S100A9 S100A9 PCOLCE PCOLCE CTSC CTSC TMEM130 TMEM130 MBP MBP HIP1 HIP1 PLK1 PLK1 PIDD1 PIDD1 CCDC22 CCDC22 RNFT1 RNFT1 NODAL NODAL DLC1 DLC1 UBQLN2 UBQLN2 BAG2 BAG2 TNP2 TNP2 BAK1 BAK1 MALT1 MALT1 A0A4W2BZH9 A0A4W2BZH9 SH3D19 SH3D19 A0A4W2C0C3 A0A4W2C0C3 OGT OGT ADAM8 ADAM8 FBLN1 FBLN1 A0A4W2C164 A0A4W2C164 CSNK1E CSNK1E BTRC BTRC PICALM PICALM FAS FAS BAG6 BAG6 A0A4W2C4X7 A0A4W2C4X7 CTSD CTSD GABARAP GABARAP CTSH CTSH BAD BAD CLEC7A CLEC7A DET1 DET1 LGMN LGMN A0A4W2CBX4 A0A4W2CBX4 HERPUD1 HERPUD1 FADD FADD HIP1R HIP1R CCBE1 CCBE1 PMAIP1 PMAIP1 RIPK2 RIPK2 DAB2 DAB2 A0A4W2CEA8 A0A4W2CEA8 PSMC4 PSMC4 SH3RF3 SH3RF3 PSENEN PSENEN A0A4W2CG00 A0A4W2CG00 A0A4W2CG09 A0A4W2CG09 AGER AGER NOP53 NOP53 TRIM67 TRIM67 RPS3 RPS3 A0A4W2CIL9 A0A4W2CIL9 CASP8AP2 CASP8AP2 CAV1 CAV1 PSME4 PSME4 AXIN2 AXIN2 BID BID NLRC4 NLRC4 ASPH ASPH DVL1 DVL1 HSPBP1 HSPBP1 PACSIN3 PACSIN3 AURKAIP1 AURKAIP1 SPON1 SPON1 NOD1 NOD1 ENO1 ENO1 RHBDD1 RHBDD1 USP5 USP5 LPCAT3 LPCAT3 XDH XDH CBFA2T3 CBFA2T3 ADRM1 ADRM1 ATP2A3 ATP2A3 RNF19A RNF19A COL4A3 COL4A3 DDRGK1 DDRGK1 CAPN3 CAPN3 ZER1 ZER1 IST1 IST1 MAP3K5 MAP3K5 PRKN PRKN GSK3B GSK3B LRRK2 LRRK2 ROCK2 ROCK2 TRIM32 TRIM32 F3 F3 SENP1 SENP1 SNX9 SNX9 APOE APOE ACER2 ACER2 FZR1 FZR1 F2R F2R F12 F12 ZC3H12A ZC3H12A PSMC6 PSMC6 PAWR PAWR MAGEF1 MAGEF1 NKX3-1 NKX3-1 CASP2 CASP2 A0A4W2D705 A0A4W2D705 FGFR4 FGFR4 MELTF MELTF PPM1F PPM1F NUB1 NUB1 TMTC3 TMTC3 CASP9 CASP9 PIAS1 PIAS1 UACA UACA BCL2L11 BCL2L11 SGTA SGTA PSME2 PSME2 CLU CLU CRADD CRADD NLRP2 NLRP2 TNP1 TNP1 RPS27L RPS27L BCL10 BCL10 CCN1 CCN1 ANTXR1 ANTXR1 PSMC1 PSMC1 PDCD2 PDCD2 PSEN1 PSEN1 APH1A APH1A BOK BOK ALOX12 ALOX12 PSME1 PSME1 ARL6IP5 ARL6IP5 PYCARD PYCARD CASP8 CASP8 CFLAR CFLAR S100A10 S100A10 CLN6 CLN6 ARIH1 ARIH1 SMAD3 SMAD3 AGTPBP1 AGTPBP1 PTK2B PTK2B TNFSF10 TNFSF10 LOC113901903 LOC113901903 PSMD14 PSMD14 TANK TANK S100A8 S100A8 MUL1 MUL1 A0A4W2EY84 A0A4W2EY84 PCOLCE2 PCOLCE2 RNF14 RNF14 NRDC NRDC MYH9 MYH9 TNIP1 TNIP1 CYFIP2 CYFIP2 FBXW9 FBXW9 APAF1 APAF1 FGL2 FGL2 PSMC2 PSMC2 SH3RF1 SH3RF1 IFT57 IFT57 MAPK9 MAPK9 TFAP4 TFAP4 TREM2 TREM2 PLK3 PLK3 FAM162A FAM162A EFNA1 EFNA1 SNX33 SNX33 LAPTM5 LAPTM5 EFNA3 EFNA3 SRC SRC SOCS4 SOCS4 AKT1 AKT1 AGBL4 AGBL4 ANKIB1 ANKIB1 RNF19B RNF19B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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TNFSF15TNF superfamily member 15. (256 aa)
RNF180Ring finger protein 180. (592 aa)
ZYG11BZyg-11 family member B, cell cycle regulator. (744 aa)
LOC113891379Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
DDA1DDA1 domain-containing protein. (102 aa)
CSNK1DCasein kinase 1 delta; Belongs to the protein kinase superfamily. (447 aa)
SNCAAlpha-synuclein; Belongs to the synuclein family. (140 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (440 aa)
APH1BAph-1 homolog B, gamma-secretase subunit. (257 aa)
NUPR1Nuclear protein 1, transcriptional regulator. (82 aa)
ADRA2AAdrenoceptor alpha 2A. (468 aa)
A0A4W2DST9DDA1 domain-containing protein. (116 aa)
SIRT1Sirtuin 1. (734 aa)
UBQLN1Ubiquilin 1. (600 aa)
DAPK1Death associated protein kinase 1. (1440 aa)
SMURF1E3 ubiquitin-protein ligase. (757 aa)
A0A4W2DPJ5DDA1 domain-containing protein. (100 aa)
SYKTyrosine-protein kinase. (628 aa)
A0A4W2DN34KH type-2 domain-containing protein. (85 aa)
NEK5NIMA related kinase 5. (832 aa)
TRIB2Tribbles pseudokinase 2. (343 aa)
WDR48WD repeat domain 48. (677 aa)
RCHY1Ring finger and CHY zinc finger domain containing 1. (261 aa)
CLEC3BC-type lectin domain family 3 member B. (203 aa)
PRELID1PRELI domain containing 1. (206 aa)
RNFT2Ring finger protein, transmembrane 2. (449 aa)
PRICKLE1Prickle planar cell polarity protein 1. (834 aa)
BBC3Uncharacterized protein. (193 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
MKRN2Makorin ring finger protein 2. (416 aa)
ANGPTL8Angiopoietin like 8. (198 aa)
PSME3Proteasome activator subunit 3. (231 aa)
RNF139Ring finger protein 139. (665 aa)
BAXBCL2 associated X, apoptosis regulator. (192 aa)
STUB1Uncharacterized protein. (592 aa)
CIDEBCell death inducing DFFA like effector b. (219 aa)
FBXW7F-box and WD repeat domain containing 7. (706 aa)
SOX7Uncharacterized protein. (534 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
RCN3Reticulocalbin 3. (328 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (266 aa)
NKD2NKD inhibitor of WNT signaling pathway 2. (483 aa)
CNTN2Contactin 2. (1040 aa)
AXIN1Axin 1. (909 aa)
NLRP6NLR family pyrin domain containing 6. (877 aa)
GRAMD4GRAM domain containing 4. (660 aa)
DDX3XDEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (645 aa)
SIRT6Sirtuin 6. (391 aa)
CLDN3Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (267 aa)
PRSS22Serine protease 22; Belongs to the peptidase S1 family. (343 aa)
BBS7Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. (715 aa)
GSNGelsolin. (846 aa)
KCNE2Potassium voltage-gated channel subfamily E regulatory subunit 2. (123 aa)
TRIB3Tribbles pseudokinase 3. (403 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
RAD23ARAD23 homolog A, nucleotide excision repair protein. (363 aa)
PLGRKTPlasminogen receptor with a C-terminal lysine. (147 aa)
USP13Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (863 aa)
DIABLOUncharacterized protein. (238 aa)
ZYG11AZyg-11 family member A, cell cycle regulator. (760 aa)
WDR20WD repeat domain 20. (607 aa)
LCKTyrosine-protein kinase. (509 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
FBXO22F-box protein 22. (404 aa)
CLDN4Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
MTCH1Mitochondrial carrier 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (389 aa)
RNF217RBR-type E3 ubiquitin transferase. (542 aa)
ATP5IF1ATP synthase inhibitory factor subunit 1. (109 aa)
HDAC2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa)
CDC20Cell division cycle 20. (499 aa)
PRR7Proline rich 7, synaptic. (269 aa)
SFRP2Secreted frizzled related protein 2. (294 aa)
CLUL1Clusterin; Belongs to the clusterin family. (469 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (492 aa)
GBAGlucosylceramidase. (536 aa)
VSIRV-set immunoregulatory receptor. (392 aa)
SART3Spliceosome associated factor 3, U4/U6 recycling protein. (957 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (843 aa)
TMEM259Transmembrane protein 259. (652 aa)
FBXW8F-box and WD repeat domain containing 8. (599 aa)
COP1COP1 E3 ubiquitin ligase. (735 aa)
OSBPL7Oxysterol-binding protein; Belongs to the OSBP family. (881 aa)
A0A4W2E2B7Uncharacterized protein. (192 aa)
RNF185Ring finger protein 185. (192 aa)
TBC1D10ATBC1 domain family member 10A. (506 aa)
HPNHepsin; Belongs to the peptidase S1 family. (454 aa)
SIRT2Sirtuin 2. (457 aa)
GSK3AProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (483 aa)
A0A4W2E5D6Uncharacterized protein. (144 aa)
RNF144BRBR-type E3 ubiquitin transferase. (304 aa)
DMWDDM1 locus, WD repeat containing. (671 aa)
CDC20BCell division cycle 20B. (514 aa)
FN1Fibronectin 1. (2601 aa)
NLRP1NLR family pyrin domain containing 1. (1410 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
ANP32BAcidic nuclear phosphoprotein 32 family member B. (269 aa)
EPHA4EPH receptor A4. (949 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (277 aa)
CARD9Caspase recruitment domain family member 9. (538 aa)
PMLPromyelocytic leukemia. (871 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (816 aa)
TNFRSF1BUncharacterized protein. (588 aa)
GRNGranulin precursor. (663 aa)
DAB2IPDAB2 interacting protein. (1267 aa)
TRIB1Tribbles pseudokinase 1. (372 aa)
LYNTyrosine-protein kinase. (491 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (333 aa)
DNAJB2DnaJ heat shock protein family (Hsp40) member B2. (325 aa)
HTRA2HtrA serine peptidase 2. (458 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
USP50Ubiquitin specific peptidase 50; Belongs to the peptidase C19 family. (373 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
EGLN3Egl-9 family hypoxia inducible factor 3. (239 aa)
ROBO1Roundabout guidance receptor 1. (1650 aa)
NCSTNNicastrin. (773 aa)
SH3RF2SH3 domain containing ring finger 2. (728 aa)
RNF144ARBR-type E3 ubiquitin transferase. (293 aa)
FOXL2Forkhead box L2. (377 aa)
RESTRE1 silencing transcription factor. (1004 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (402 aa)
S100A9S100 calcium binding protein A9; Belongs to the S-100 family. (156 aa)
PCOLCEProcollagen C-endopeptidase enhancer. (476 aa)
CTSCCathepsin C; Belongs to the peptidase C1 family. (463 aa)
TMEM130Transmembrane protein 130. (471 aa)
MBPUncharacterized protein. (497 aa)
HIP1Huntingtin interacting protein 1. (1037 aa)
PLK1Serine/threonine-protein kinase PLK. (602 aa)
PIDD1P53-induced death domain protein 1. (946 aa)
CCDC22Coiled-coil domain containing 22. (594 aa)
RNFT1Ring finger protein, transmembrane 1. (433 aa)
NODALNodal growth differentiation factor. (346 aa)
DLC1DLC1 Rho GTPase activating protein. (1169 aa)
UBQLN2Ubiquilin 2. (624 aa)
BAG2BCL2 associated athanogene 2. (211 aa)
TNP2Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. (132 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
MALT1MALT1 paracaspase. (850 aa)
A0A4W2BZH9Uncharacterized protein. (727 aa)
SH3D19SH3 domain containing 19. (1065 aa)
A0A4W2C0C340S ribosomal protein S27. (95 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1036 aa)
ADAM8ADAM metallopeptidase domain 8. (772 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (711 aa)
A0A4W2C164Uncharacterized protein; Belongs to the heat shock protein 70 family. (715 aa)
CSNK1EProtein kinase domain-containing protein. (490 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (616 aa)
PICALMPhosphatidylinositol binding clathrin assembly protein. (686 aa)
FASFas cell surface death receptor. (323 aa)
BAG6BCL2 associated athanogene 6. (1164 aa)
A0A4W2C4X7Protein kinase domain-containing protein. (710 aa)
CTSDPeptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (485 aa)
GABARAPGABA type A receptor-associated protein. (117 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (335 aa)
BADBCL2 associated agonist of cell death. (168 aa)
CLEC7AC-type lectin domain containing 7A. (247 aa)
DET1Uncharacterized protein. (595 aa)
LGMNLegumain. (433 aa)
A0A4W2CBX4Uncharacterized protein. (152 aa)
HERPUD1Homocysteine inducible ER protein with ubiquitin like domain 1. (389 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (209 aa)
HIP1RHuntingtin interacting protein 1 related. (1066 aa)
CCBE1Collagen and calcium binding EGF domains 1. (408 aa)
PMAIP1Phorbol-12-myristate-13-acetate-induced protein 1. (54 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (539 aa)
DAB2DAB adaptor protein 2. (779 aa)
A0A4W2CEA8Uncharacterized protein. (102 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
SH3RF3SH3 domain containing ring finger 3. (887 aa)
PSENENPresenilin enhancer, gamma-secretase subunit. (101 aa)
A0A4W2CG00Uncharacterized protein. (121 aa)
A0A4W2CG09MAGE domain-containing protein. (153 aa)
AGERAdvanced glycosylation end-product specific receptor. (416 aa)
NOP53NOP53 ribosome biogenesis factor. (534 aa)
TRIM67Tripartite motif containing 67. (780 aa)
RPS3Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (281 aa)
A0A4W2CIL9Uncharacterized protein. (423 aa)
CASP8AP2Caspase 8 associated protein 2. (1973 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (211 aa)
PSME4Proteasome activator subunit 4. (1843 aa)
AXIN2Axin 2. (836 aa)
BIDBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (193 aa)
NLRC4NLR family CARD domain containing 4. (1017 aa)
ASPHAspartate beta-hydroxylase. (767 aa)
DVL1Dishevelled segment polarity protein 1. (708 aa)
HSPBP1HSPA (Hsp70) binding protein 1. (357 aa)
PACSIN3Protein kinase C and casein kinase substrate in neurons 3. (435 aa)
AURKAIP1Aurora kinase A interacting protein 1. (199 aa)
SPON1Spondin 1. (807 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (954 aa)
ENO1Enolase 1. (500 aa)
RHBDD1Rhomboid domain containing 1. (322 aa)
USP5Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (852 aa)
LPCAT3Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (485 aa)
XDHXanthine dehydrogenase. (1332 aa)
CBFA2T3CBFA2/RUNX1 partner transcriptional co-repressor 3. (631 aa)
ADRM1Adhesion regulating molecule 1. (410 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1044 aa)
RNF19ARBR-type E3 ubiquitin transferase. (838 aa)
COL4A3Collagen type IV alpha 3 chain. (1649 aa)
DDRGK1DDRGK domain containing 1. (322 aa)
CAPN3Calpain 3; Belongs to the peptidase C2 family. (822 aa)
ZER1Zyg-11 related cell cycle regulator. (766 aa)
IST1IST1 factor associated with ESCRT-III. (364 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1366 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (460 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (432 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1469 aa)
TRIM32Tripartite motif containing 32. (653 aa)
F3Coagulation factor III, tissue factor. (370 aa)
SENP1SUMO specific peptidase 1. (749 aa)
SNX9Sorting nexin. (624 aa)
APOEApolipoprotein E. (349 aa)
ACER2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (319 aa)
FZR1Fizzy and cell division cycle 20 related 1. (523 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (427 aa)
F12Coagulation factor XII. (604 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (583 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
PAWRPro-apoptotic WT1 regulator. (344 aa)
MAGEF1MAGE family member F1. (307 aa)
NKX3-1NK3 homeobox 1. (239 aa)
CASP2Caspase 2; Belongs to the peptidase C14A family. (452 aa)
A0A4W2D705Clusterin; Belongs to the clusterin family. (448 aa)
FGFR4Fibroblast growth factor receptor. (800 aa)
MELTFMelanotransferrin; Belongs to the transferrin family. (739 aa)
PPM1FProtein phosphatase, Mg2+/Mn2+ dependent 1F. (672 aa)
NUB1Negative regulator of ubiquitin like proteins 1. (615 aa)
TMTC3Transmembrane O-mannosyltransferase targeting cadherins 3. (918 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (452 aa)
PIAS1Protein inhibitor of activated STAT 1. (702 aa)
UACAUveal autoantigen with coiled-coil domains and ankyrin repeats. (1416 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (195 aa)
SGTASmall glutamine rich tetratricopeptide repeat containing alpha. (363 aa)
PSME2Proteasome activator subunit 2. (239 aa)
CLUClusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (439 aa)
CRADDCASP2 and RIPK1 domain containing adaptor with death domain. (287 aa)
NLRP2NLR family pyrin domain containing 2. (974 aa)
TNP1Transition protein 1. (55 aa)
RPS27L40S ribosomal protein S27. (102 aa)
BCL10BCL10 immune signaling adaptor. (230 aa)
CCN1Cellular communication network factor 1. (463 aa)
ANTXR1ANTXR cell adhesion molecule 1. (564 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (462 aa)
PDCD2Programmed cell death 2. (344 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (478 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
BOKBCL2 family apoptosis regulator BOK. (213 aa)
ALOX12Arachidonate 12-lipoxygenase, 12S type. (676 aa)
PSME1Proteasome activator subunit 1. (249 aa)
ARL6IP5PRA1 family protein. (188 aa)
PYCARDPYD and CARD domain containing. (195 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (485 aa)
CFLARCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (511 aa)
S100A10S100 calcium binding protein A10; Belongs to the S-100 family. (97 aa)
CLN6CLN6 transmembrane ER protein. (380 aa)
ARIH1RBR-type E3 ubiquitin transferase. (555 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
AGTPBP1ATP/GTP binding protein 1. (1277 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1008 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (287 aa)
LOC113901903Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (320 aa)
TANKTRAF family member associated NFKB activator. (481 aa)
S100A8S100 calcium binding protein A8; Belongs to the S-100 family. (81 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (350 aa)
A0A4W2EY84Uncharacterized protein. (341 aa)
PCOLCE2Procollagen C-endopeptidase enhancer 2. (401 aa)
RNF14RBR-type E3 ubiquitin transferase. (542 aa)
NRDCNardilysin convertase. (1231 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1986 aa)
TNIP1TNFAIP3 interacting protein 1. (631 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
FBXW9F-box and WD repeat domain containing 9. (458 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1249 aa)
FGL2Fibrinogen like 2. (441 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
SH3RF1SH3 domain containing ring finger 1. (828 aa)
IFT57Intraflagellar transport 57. (429 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
TFAP4Transcription factor AP-4. (335 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (244 aa)
PLK3Serine/threonine-protein kinase PLK. (647 aa)
FAM162AFamily with sequence similarity 162 member A. (156 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (325 aa)
SNX33Sorting nexin. (571 aa)
LAPTM5Lysosomal protein transmembrane 5. (264 aa)
EFNA3Ephrin RBD domain-containing protein; Belongs to the ephrin family. (238 aa)
SRCTyrosine-protein kinase. (559 aa)
SOCS4Suppressor of cytokine signaling 4. (440 aa)
AKT1Non-specific serine/threonine protein kinase. (747 aa)
AGBL4ATP/GTP binding protein like 4. (320 aa)
ANKIB1RBR-type E3 ubiquitin transferase. (1091 aa)
RNF19BRBR-type E3 ubiquitin transferase. (687 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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