STRINGSTRING
P2RX6 P2RX6 ENPP1 ENPP1 WNT10B WNT10B RAPGEF3 RAPGEF3 EZR EZR HCN4 HCN4 ZFP36L1 ZFP36L1 DMTN DMTN HCN2 HCN2 ITPR2 ITPR2 PKD2 PKD2 P2RY11 P2RY11 SLC26A3 SLC26A3 INPP5K INPP5K HSP90B1 HSP90B1 PIK3CG PIK3CG VGF VGF AKAP9 AKAP9 P2RY12 P2RY12 A0A4W2DVU2 A0A4W2DVU2 P2RX7 P2RX7 NDUFS4 NDUFS4 WT1 WT1 PDE2A PDE2A AQP9 AQP9 IGFBP5 IGFBP5 OXT OXT P2RX1 P2RX1 P2RX2 P2RX2 GPD1 GPD1 A0A4W2EQN1 A0A4W2EQN1 A0A4W2EX93 A0A4W2EX93 SLC5A5 SLC5A5 ABCC9 ABCC9 HCN1 HCN1 RAPGEF2 RAPGEF2 CIB2 CIB2 RAP1A RAP1A P2RX3 P2RX3 KCNQ1 KCNQ1 TRPM4 TRPM4 SSH1 SSH1 RAP1B RAP1B HCN3 HCN3 AQP1 AQP1 TRIM16 TRIM16 A0A4W2I4T1 A0A4W2I4T1 RFC3 RFC3 AQP8 AQP8 FDX1 FDX1 TRPC3 TRPC3 CASP1 CASP1 PDXP PDXP PER1 PER1 KCNJ11 KCNJ11 AKAP6 AKAP6 SLC26A6 SLC26A6 P2RX4 P2RX4 P2RY6 P2RY6 NT5E NT5E CFTR CFTR DUOX1 DUOX1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
P2RX6P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (375 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (940 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (433 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (923 aa)
EZREzrin. (638 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1201 aa)
ZFP36L1ZFP36 ring finger protein like 1. (323 aa)
DMTNDematin actin binding protein. (467 aa)
HCN2Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (902 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (1071 aa)
P2RY11Purinergic receptor P2Y11; Belongs to the G-protein coupled receptor 1 family. (338 aa)
SLC26A3Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (760 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (449 aa)
HSP90B1Heat shock protein 90 beta family member 1. (808 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1171 aa)
VGFVGF nerve growth factor inducible. (656 aa)
AKAP9A-kinase anchoring protein 9. (3907 aa)
P2RY12Purinergic receptor P2Y12. (342 aa)
A0A4W2DVU2PAS domain-containing protein. (743 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
NDUFS4NADH:ubiquinone oxidoreductase subunit S4. (175 aa)
WT1WT1 transcription factor. (518 aa)
PDE2APhosphodiesterase. (943 aa)
AQP9Aquaporin 9; Belongs to the MIP/aquaporin (TC 1.A.8) family. (295 aa)
IGFBP5Insulin like growth factor binding protein 5. (271 aa)
OXTOxytocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family. (172 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (535 aa)
GPD1Glycerol-3-phosphate dehydrogenase [NAD(+)]. (455 aa)
A0A4W2EQN1Phorbol-ester/DAG-type domain-containing protein. (322 aa)
A0A4W2EX93BHLH domain-containing protein. (119 aa)
SLC5A5Solute carrier family 5 member 5; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (642 aa)
ABCC9ATP binding cassette subfamily C member 9. (1549 aa)
HCN1Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (877 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1689 aa)
CIB2Calcium and integrin binding family member 2. (296 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (670 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1207 aa)
SSH1Slingshot protein phosphatase 1. (988 aa)
RAP1BUncharacterized protein. (184 aa)
HCN3Hyperpolarization activated cyclic nucleotide gated potassium channel 3. (783 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
TRIM16Uncharacterized protein. (562 aa)
A0A4W2I4T1Uncharacterized protein. (139 aa)
RFC3Replication factor C subunit 3. (356 aa)
AQP8Aquaporin 8; Belongs to the MIP/aquaporin (TC 1.A.8) family. (330 aa)
FDX1Ferredoxin 1. (196 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (873 aa)
CASP1Uncharacterized protein; Belongs to the peptidase C14A family. (416 aa)
PDXPPyridoxal phosphatase; Belongs to the HAD-like hydrolase superfamily. (296 aa)
PER1Period circadian regulator 1. (1285 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (388 aa)
AKAP6A-kinase anchoring protein 6. (2319 aa)
SLC26A6Solute carrier family 26 member 6. (763 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (394 aa)
P2RY6Pyrimidinergic receptor P2Y6. (328 aa)
NT5E5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (574 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1481 aa)
DUOX1Dual oxidase 1. (1553 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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