STRINGSTRING
FLT1 FLT1 NRP2 NRP2 BMPR1A BMPR1A TGFA TGFA PROK2 PROK2 RASA1 RASA1 HAND2 HAND2 GLUL GLUL HPGD HPGD TMEM100 TMEM100 LOXL2 LOXL2 VEZF1 VEZF1 NPRL3 NPRL3 VASH1 VASH1 EDN1 EDN1 POFUT1 POFUT1 EGR3 EGR3 NOG NOG SOS1 SOS1 SGCD SGCD EPHB3 EPHB3 EPGN EPGN E2F8 E2F8 B4GALT1 B4GALT1 JUN JUN HDAC7 HDAC7 CIB1 CIB1 FZD4 FZD4 HEY1 HEY1 MYDGF MYDGF FGF10 FGF10 GJA1 GJA1 HIF1A HIF1A EDN2 EDN2 GAB1 GAB1 PRDM1 PRDM1 EPHB2 EPHB2 CLIC4 CLIC4 FBXW7 FBXW7 TEAD2 TEAD2 EPHB1 EPHB1 HAS2 HAS2 SMAD7 SMAD7 RASIP1 RASIP1 PGF PGF SMO SMO ARID2 ARID2 GJA5 GJA5 FAP FAP APLNR APLNR NR2F2 NR2F2 GNA13 GNA13 TSPAN12 TSPAN12 ITGB1 ITGB1 MFGE8 MFGE8 PRKCA PRKCA NTRK2 NTRK2 ANGPT2 ANGPT2 CCM2 CCM2 GREM1 GREM1 ELK3 ELK3 SPRED1 SPRED1 SLIT2 SLIT2 NR4A1 NR4A1 C1GALT1 C1GALT1 EMC10 EMC10 PARVA PARVA STK4 STK4 FGF8 FGF8 RSPO3 RSPO3 TBX20 TBX20 AKT1 AKT1 PRKX PRKX JAG1 JAG1 APOLD1 APOLD1 EFNA1 EFNA1 SHC1 SHC1 ANGPTL4 ANGPTL4 WASF2 WASF2 PDGFRA PDGFRA STRA6 STRA6 ETV2 ETV2 ITGAV ITGAV TIE1 TIE1 EDNRA EDNRA FGF9 FGF9 JMJD6 JMJD6 GLMN GLMN KLF5 KLF5 CALCRL CALCRL NRCAM NRCAM COL3A1 COL3A1 LDLR LDLR HS6ST1 HS6ST1 FBXW9 FBXW9 SEMA3E SEMA3E COL18A1 COL18A1 EMCN EMCN ANGPTL3 ANGPTL3 MYH9 MYH9 NAXE NAXE SEMA4A SEMA4A EPHA2 EPHA2 ITGB8 ITGB8 TGFBI TGFBI A0A4W2EY84 A0A4W2EY84 PIK3R3 PIK3R3 TIPARP TIPARP GBX2 GBX2 ACKR3 ACKR3 PTK2B PTK2B HPSE HPSE NOTCH2 NOTCH2 E2F7 E2F7 SHH SHH LOX LOX WARS2 WARS2 RBM15 RBM15 VSTM4 VSTM4 S1PR1 S1PR1 MMRN2 MMRN2 A0A4W2ENI5 A0A4W2ENI5 CCN1 CCN1 ATP5F1B ATP5F1B SPI1 SPI1 OTULIN OTULIN THBS1 THBS1 CCN2 CCN2 COL4A1 COL4A1 ANGPT4 ANGPT4 BMP4 BMP4 CYP1B1 CYP1B1 SCG2 SCG2 BMPR2 BMPR2 APOB APOB VEGFC VEGFC CXCL17 CXCL17 ITGB1BP1 ITGB1BP1 ADGRF5 ADGRF5 FGF2 FGF2 SOX17 SOX17 ADGRA2 ADGRA2 ENG ENG A0A4W2EB18 A0A4W2EB18 PRRX1 PRRX1 HOXA3 HOXA3 A0A4W2E9P1 A0A4W2E9P1 TGFBR2 TGFBR2 COL15A1 COL15A1 AAMP AAMP EYA1 EYA1 FN1 FN1 NF1 NF1 TNNI3 TNNI3 COL22A1 COL22A1 NRP1 NRP1 ADIPOR2 ADIPOR2 GPR15 GPR15 ENPEP ENPEP LEF1 LEF1 MEIS1 MEIS1 CLEC14A CLEC14A VEGFA VEGFA HOXB3 HOXB3 APELA APELA GPLD1 GPLD1 PROX1 PROX1 IL18 IL18 NOTCH1 NOTCH1 SFRP2 SFRP2 TBX2 TBX2 HOXB13 HOXB13 LRP2 LRP2 CXCR3 CXCR3 MED1 MED1 SAT1 SAT1 A0A4W2DSW5 A0A4W2DSW5 SIRT1 SIRT1 FOXN1 FOXN1 LRP5 LRP5 SERPINF2 SERPINF2 GPX1 GPX1 MCAM MCAM SETD2 SETD2 PAXIP1 PAXIP1 PIK3CA PIK3CA UBP1 UBP1 ANGPTL6 ANGPTL6 TBX4 TBX4 SYK SYK JUNB JUNB PROK1 PROK1 NFATC4 NFATC4 PKNOX1 PKNOX1 HAND1 HAND1 HES1 HES1 ITGA5 ITGA5 AMOTL2 AMOTL2 HEG1 HEG1 NDNF NDNF TAL1 TAL1 TBXT TBXT ADRA2B ADRA2B SEC24B SEC24B ROBO1 ROBO1 LEPR LEPR PDGFRB PDGFRB FGF1 FGF1 PKD2 PKD2 KRIT1 KRIT1 COMP COMP TCF21 TCF21 MEOX2 MEOX2 ZC3H12A ZC3H12A SIX1 SIX1 KDR KDR ZFP36L1 ZFP36L1 FLT4 FLT4 PDCD10 PDCD10 HOXA7 HOXA7 PXDN PXDN CCN3 CCN3 FZD5 FZD5 APOE APOE GDF2 GDF2 PDCL3 PDCL3 DLL1 DLL1 ACVRL1 ACVRL1 PTPRB PTPRB FKBP10 FKBP10 TEK TEK LEP LEP GJC1 GJC1 DLL4 DLL4 SOX18 SOX18 CITED2 CITED2 PANK2 PANK2 FGF18 FGF18 RORA RORA MYO1E MYO1E ZFPM2 ZFPM2 EFNB2 EFNB2 HOXA13 HOXA13 IHH IHH A0A4W2CPH3 A0A4W2CPH3 RECK RECK A0A4W2CP07 A0A4W2CP07 SHB SHB TGFBR1 TGFBR1 ANGPT1 ANGPT1 PTK2 PTK2 BMPER BMPER EPAS1 EPAS1 SRF SRF CUL7 CUL7 CAV1 CAV1 TGFB1 TGFB1 CCDC134 CCDC134 CHD7 CHD7 NR2E1 NR2E1 RAMP2 RAMP2 EIF2AK3 EIF2AK3 PLXDC2 PLXDC2 WNT11 WNT11 SGPL1 SGPL1 PLCD3 PLCD3 HEY2 HEY2 MMP2 MMP2 ESM1 ESM1 FOXF1 FOXF1 ANPEP ANPEP ADGRG1 ADGRG1 WNT7A WNT7A ZMIZ1 ZMIZ1 A0A4W2C839 A0A4W2C839 MYO18B MYO18B MYOCD MYOCD PLXDC1 PLXDC1 ADAM8 ADAM8 FOXH1 FOXH1 YAP1 YAP1 CDH13 CDH13 BAK1 BAK1 TFAP2B TFAP2B AMOTL1 AMOTL1 A0A4W2BXB8 A0A4W2BXB8 NRARP NRARP CDH2 CDH2 A0A4W2BU79 A0A4W2BU79 THY1 THY1 PLXND1 PLXND1 LAMA1 LAMA1 ADTRP ADTRP CTNNB1 CTNNB1 ROBO4 ROBO4 PRCP PRCP EPHB4 EPHB4 JAM3 JAM3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1467 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (931 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
TGFATransforming growth factor alpha. (228 aa)
PROK2Prokineticin 2. (128 aa)
RASA1RAS p21 protein activator 1. (1044 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
GLULGlutamine synthetase. (373 aa)
HPGD15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa)
TMEM100Transmembrane protein 100. (134 aa)
LOXL2Lysyl oxidase like 2. (774 aa)
VEZF1Vascular endothelial zinc finger 1. (517 aa)
NPRL3NPR3 like, GATOR1 complex subunit. (569 aa)
VASH1Vasohibin 1. (363 aa)
EDN1Endothelin 1. (202 aa)
POFUT1Protein O-fucosyltransferase 1. (391 aa)
EGR3Early growth response 3. (387 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1598 aa)
SGCDSarcoglycan delta. (289 aa)
EPHB3EPH receptor B3. (997 aa)
EPGNEpithelial mitogen. (153 aa)
E2F8E2F transcription factor 8. (868 aa)
B4GALT1Beta-1,4-galactosyltransferase 1. (402 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (335 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1092 aa)
CIB1Calcium and integrin binding 1. (191 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (308 aa)
MYDGFMyeloid derived growth factor. (174 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (383 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (842 aa)
EDN2Endothelin 2. (186 aa)
GAB1GRB2 associated binding protein 1. (751 aa)
PRDM1PR/SET domain 1. (842 aa)
EPHB2EPH receptor B2. (986 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa)
FBXW7F-box and WD repeat domain containing 7. (706 aa)
TEAD2TEA domain transcription factor 2. (451 aa)
EPHB1EPH receptor B1. (984 aa)
HAS2Uncharacterized protein. (558 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
RASIP1Ras interacting protein 1. (963 aa)
PGFPlacental growth factor; Belongs to the PDGF/VEGF growth factor family. (177 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (780 aa)
ARID2AT-rich interaction domain 2. (1834 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (359 aa)
FAPFibroblast activation protein alpha; Belongs to the peptidase S9B family. (760 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (368 aa)
NR2F2Nuclear receptor subfamily 2 group F member 2. (414 aa)
GNA13G protein subunit alpha 13. (377 aa)
TSPAN12Tetraspanin. (305 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
MFGE8Uncharacterized protein. (572 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
NTRK2Tyrosine-protein kinase receptor. (837 aa)
ANGPT2Angiopoietin 2. (496 aa)
CCM2CCM2 scaffold protein. (518 aa)
GREM1Gremlin 1, DAN family BMP antagonist. (240 aa)
ELK3ETS transcription factor ELK3. (402 aa)
SPRED1Sprouty related EVH1 domain containing 1. (443 aa)
SLIT2Slit guidance ligand 2. (1543 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (598 aa)
C1GALT1Core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1. (368 aa)
EMC10ER membrane protein complex subunit 10. (320 aa)
PARVAParvin alpha. (455 aa)
STK4Serine/threonine kinase 4. (487 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
RSPO3R-spondin 3. (273 aa)
TBX20T-box transcription factor 20. (449 aa)
AKT1Non-specific serine/threonine protein kinase. (747 aa)
PRKXUncharacterized protein; Belongs to the protein kinase superfamily. (347 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
APOLD1Apolipoprotein L domain containing 1. (246 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (325 aa)
SHC1SHC adaptor protein 1. (584 aa)
ANGPTL4Angiopoietin like 4. (410 aa)
WASF2WASP family member 2. (493 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1098 aa)
STRA6Stimulated by retinoic acid 6. (668 aa)
ETV2ETS variant 2. (331 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1212 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (414 aa)
GLMNGlomulin, FKBP associated protein. (592 aa)
KLF5Kruppel like factor 5. (454 aa)
CALCRLCalcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa)
NRCAMNeuronal cell adhesion molecule. (1211 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
LDLRLow density lipoprotein receptor. (845 aa)
HS6ST1Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (411 aa)
FBXW9F-box and WD repeat domain containing 9. (458 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (763 aa)
COL18A1Collagen type XVIII alpha 1 chain. (1761 aa)
EMCNUncharacterized protein. (282 aa)
ANGPTL3Angiopoietin like 3. (459 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1986 aa)
NAXENAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (363 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (851 aa)
EPHA2EPH receptor A2. (1007 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (772 aa)
TGFBITransforming growth factor beta induced. (683 aa)
A0A4W2EY84Uncharacterized protein. (341 aa)
PIK3R3Uncharacterized protein. (461 aa)
TIPARPTCDD inducible poly(ADP-ribose) polymerase. (656 aa)
GBX2Gastrulation brain homeobox 2. (349 aa)
ACKR3Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (362 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1008 aa)
HPSEHeparanase. (661 aa)
NOTCH2Notch receptor 2. (2471 aa)
E2F7E2F transcription factor 7. (912 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (464 aa)
LOXLysyl oxidase. (418 aa)
WARS2Tryptophanyl tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (415 aa)
RBM15RNA binding motif protein 15. (962 aa)
VSTM4V-set and transmembrane domain containing 4. (319 aa)
S1PR1Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
MMRN2Multimerin 2. (932 aa)
A0A4W2ENI5RNAse_Pc domain-containing protein; Belongs to the pancreatic ribonuclease family. (148 aa)
CCN1Cellular communication network factor 1. (463 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa)
SPI1Spi-1 proto-oncogene. (384 aa)
OTULINOTU deubiquitinase with linear linkage specificity. (509 aa)
THBS1Thrombospondin 1. (1170 aa)
CCN2Cellular communication network factor 2. (464 aa)
COL4A1Collagen type IV alpha 1 chain. (1669 aa)
ANGPT4Angiopoietin 4. (560 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (539 aa)
SCG2Secretogranin II. (613 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
APOBApolipoprotein B. (4567 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (419 aa)
CXCL17Uncharacterized protein. (118 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
ADGRF5Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1418 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
SOX17SRY-box transcription factor 17. (410 aa)
ADGRA2Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1343 aa)
ENGEndoglin. (649 aa)
A0A4W2EB18Uncharacterized protein. (516 aa)
PRRX1Paired related homeobox 1. (245 aa)
HOXA3Homeobox A3. (442 aa)
A0A4W2E9P1Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family. (372 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa)
COL15A1Collagen type XV alpha 1 chain. (1382 aa)
AAMPAngio associated migratory cell protein. (435 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (700 aa)
FN1Fibronectin 1. (2601 aa)
NF1Neurofibromin 1. (3024 aa)
TNNI3Troponin I3, cardiac type. (212 aa)
COL22A1Collagen type XXII alpha 1 chain. (1623 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
ADIPOR2Adiponectin receptor 2. (386 aa)
GPR15G protein-coupled receptor 15; Belongs to the G-protein coupled receptor 1 family. (358 aa)
ENPEPAminopeptidase. (956 aa)
LEF1Lymphoid enhancer binding factor 1. (430 aa)
MEIS1Meis homeobox 1. (492 aa)
CLEC14AC-type lectin domain containing 14A. (475 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (394 aa)
HOXB3Homeobox B3. (426 aa)
APELAUncharacterized protein. (54 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (843 aa)
PROX1Prospero homeobox 1. (738 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
NOTCH1Notch receptor 1. (2533 aa)
SFRP2Secreted frizzled related protein 2. (294 aa)
TBX2T-box transcription factor 2. (714 aa)
HOXB13Homeobox B13. (285 aa)
LRP2LDL receptor related protein 2. (4647 aa)
CXCR3C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (409 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1575 aa)
SAT1Spermidine/spermine N1-acetyltransferase 1. (171 aa)
A0A4W2DSW5Uncharacterized protein. (191 aa)
SIRT1Sirtuin 1. (734 aa)
FOXN1Forkhead box N1. (644 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1629 aa)
SERPINF2Serpin family F member 2; Belongs to the serpin family. (492 aa)
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (204 aa)
MCAMMelanoma cell adhesion molecule. (645 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2563 aa)
PAXIP1PAX interacting protein 1. (983 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
UBP1Upstream binding protein 1. (536 aa)
ANGPTL6Angiopoietin like 6. (466 aa)
TBX4T-box transcription factor 4. (550 aa)
SYKTyrosine-protein kinase. (628 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
PROK1Prokineticin 1. (105 aa)
NFATC4Nuclear factor of activated T cells 4. (979 aa)
PKNOX1PBX/knotted 1 homeobox 1. (436 aa)
HAND1Heart and neural crest derivatives expressed 1. (394 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1164 aa)
AMOTL2Angiomotin like 2. (823 aa)
HEG1Heart development protein with EGF like domains 1. (1471 aa)
NDNFNeuron derived neurotrophic factor. (573 aa)
TAL1TAL bHLH transcription factor 1, erythroid differentiation factor. (328 aa)
TBXTT-box transcription factor T. (435 aa)
ADRA2BAdrenoceptor alpha 2B. (475 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (1459 aa)
ROBO1Roundabout guidance receptor 1. (1650 aa)
LEPRLeptin receptor. (1165 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1103 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (1071 aa)
KRIT1Uncharacterized protein. (736 aa)
COMPCartilage oligomeric matrix protein. (756 aa)
TCF21Transcription factor 21. (179 aa)
MEOX2Mesenchyme homeobox 2. (303 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (583 aa)
SIX1SIX homeobox 1. (284 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
ZFP36L1ZFP36 ring finger protein like 1. (323 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1365 aa)
PDCD10Programmed cell death 10. (212 aa)
HOXA7Homeobox A7. (238 aa)
PXDNPeroxidasin. (1479 aa)
CCN3Cellular communication network factor 3. (355 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
APOEApolipoprotein E. (349 aa)
GDF2Growth differentiation factor 2. (431 aa)
PDCL3Phosducin like 3. (240 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (722 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
PTPRBProtein tyrosine phosphatase receptor type B. (2211 aa)
FKBP10Peptidylprolyl isomerase. (567 aa)
TEKTEK receptor tyrosine kinase. (1125 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
GJC1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (396 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
SOX18SRY-box transcription factor 18. (389 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa)
PANK2Pantothenate kinase 2. (447 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
RORARAR related orphan receptor A. (527 aa)
MYO1EMyosin IE; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1108 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1151 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (342 aa)
HOXA13Homeobox A13. (388 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (412 aa)
A0A4W2CPH3RING-type domain-containing protein. (5204 aa)
RECKReversion inducing cysteine rich protein with kazal motifs. (970 aa)
A0A4W2CP07RING-type domain-containing protein. (5131 aa)
SHBSH2 domain-containing protein. (507 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
ANGPT1Angiopoietin 1. (498 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1139 aa)
BMPERBMP binding endothelial regulator. (685 aa)
EPAS1Endothelial PAS domain protein 1. (928 aa)
SRFSerum response factor. (509 aa)
CUL7Cullin 7; Belongs to the cullin family. (1701 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (211 aa)
TGFB1Transforming growth factor beta 1. (443 aa)
CCDC134Coiled-coil domain containing 134. (229 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2990 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (385 aa)
RAMP2Receptor activity modifying protein 2. (182 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1115 aa)
PLXDC2Plexin domain containing 2. (537 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (568 aa)
PLCD3Phosphoinositide phospholipase C. (815 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
MMP2Matrix metallopeptidase 2. (661 aa)
ESM1Endothelial cell specific molecule 1. (184 aa)
FOXF1Forkhead box F1. (481 aa)
ANPEPAminopeptidase. (966 aa)
ADGRG1Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (746 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
ZMIZ1Zinc finger MIZ-type containing 1. (1112 aa)
A0A4W2C839BZIP domain-containing protein. (376 aa)
MYO18BMyosin XVIIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2523 aa)
MYOCDMyocardin. (981 aa)
PLXDC1Plexin domain containing 1. (500 aa)
ADAM8ADAM metallopeptidase domain 8. (772 aa)
FOXH1Forkhead box H1. (359 aa)
YAP1Yes associated protein 1. (507 aa)
CDH13Cadherin 13. (713 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
TFAP2BTranscription factor AP-2 beta. (488 aa)
AMOTL1Angiomotin like 1. (1118 aa)
A0A4W2BXB8Uncharacterized protein. (414 aa)
NRARPNOTCH regulated ankyrin repeat protein. (114 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (1318 aa)
A0A4W2BU79PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (502 aa)
THY1Thy-1 cell surface antigen. (161 aa)
PLXND1Plexin D1. (1930 aa)
LAMA1Laminin subunit alpha 1. (3131 aa)
ADTRPAndrogen dependent TFPI regulating protein. (230 aa)
CTNNB1Catenin beta 1. (774 aa)
ROBO4Roundabout guidance receptor 4. (1003 aa)
PRCPProlylcarboxypeptidase. (499 aa)
EPHB4EPH receptor B4. (987 aa)
JAM3Junctional adhesion molecule 3. (353 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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