STRINGSTRING
EIF4A3 EIF4A3 SETD2 SETD2 TWIST1 TWIST1 DLX2 DLX2 SLC39A1 SLC39A1 SIX1 SIX1 GRHL2 GRHL2 SIX4 SIX4 MMP14 MMP14 GLI3 GLI3 TGFBR1 TGFBR1 FGFR2 FGFR2 NIPBL NIPBL MMP16 MMP16 MED12 MED12 RUNX2 RUNX2 NODAL NODAL SMAD2 SMAD2 TFAP2A TFAP2A IFT140 IFT140 WNT9B WNT9B LHX1 LHX1 SIX2 SIX2 CHST11 CHST11 TBX15 TBX15 FGF8 FGF8 PDGFRA PDGFRA NDST1 NDST1 WDR19 WDR19 SMAD3 SMAD3 ALX3 ALX3 SLC39A3 SLC39A3 PAX5 PAX5 HOXA2 HOXA2 BMP4 BMP4 TULP3 TULP3 MTHFD1L MTHFD1L PRRX1 PRRX1 TGFBR2 TGFBR2 RDH10 RDH10 IRX5 IRX5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EIF4A3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (411 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2563 aa)
TWIST1Twist family bHLH transcription factor 1. (201 aa)
DLX2Distal-less homeobox 2. (331 aa)
SLC39A1Solute carrier family 39 member 1. (324 aa)
SIX1SIX homeobox 1. (284 aa)
GRHL2Grainyhead like transcription factor 2. (609 aa)
SIX4SIX homeobox 4. (786 aa)
MMP14Matrix metallopeptidase 14. (582 aa)
GLI3GLI family zinc finger 3. (1587 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
NIPBLNipped-B protein. (2698 aa)
MMP16Matrix metallopeptidase 16. (607 aa)
MED12Mediator complex subunit 12. (2024 aa)
RUNX2RUNX family transcription factor 2. (527 aa)
NODALNodal growth differentiation factor. (346 aa)
SMAD2Mothers against decapentaplegic homolog. (626 aa)
TFAP2ATranscription factor AP-2 alpha. (439 aa)
IFT140Intraflagellar transport 140. (1457 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
LHX1LIM homeobox 1. (406 aa)
SIX2SIX homeobox 2. (296 aa)
CHST11Carbohydrate sulfotransferase. (352 aa)
TBX15T-box transcription factor 15. (602 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1098 aa)
NDST1N-deacetylase and N-sulfotransferase 1. (904 aa)
WDR19WD repeat domain 19. (1342 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
ALX3ALX homeobox 3. (343 aa)
SLC39A3Solute carrier family 39 member 3. (314 aa)
PAX5Paired box 5. (391 aa)
HOXA2Homeobox A2. (372 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
TULP3Tubby-like protein; Belongs to the TUB family. (482 aa)
MTHFD1LMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (976 aa)
PRRX1Paired related homeobox 1. (245 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
IRX5Iroquois homeobox 5. (515 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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