STRINGSTRING
CHST11 CHST11 ZEB1 ZEB1 A0A4W2D3H6 A0A4W2D3H6 MMP14 MMP14 DLG1 DLG1 CER1 CER1 OSR1 OSR1 SERPINH1 SERPINH1 WNT10B WNT10B GLI3 GLI3 DHRS3 DHRS3 CITED2 CITED2 FGF18 FGF18 SDC3 SDC3 NEUROG1 NEUROG1 WDR19 WDR19 PPARGC1B PPARGC1B CDX1 CDX1 NDST1 NDST1 CBS CBS ANXA6 ANXA6 A0A4W2F2V6 A0A4W2F2V6 COL3A1 COL3A1 HOXD3 HOXD3 SATB2 SATB2 SFRP4 SFRP4 COL1A1 COL1A1 PDGFRA PDGFRA FGR FGR OSR2 OSR2 SHOX2 SHOX2 FGF8 FGF8 IFT80 IFT80 NAB2 NAB2 OTOR OTOR MSX1 MSX1 ZFAND5 ZFAND5 MMP13 MMP13 NPPC NPPC RFLNA RFLNA ATG9A ATG9A TBX15 TBX15 COMMD3 COMMD3 FGF4 FGF4 SIX2 SIX2 LHX1 LHX1 WDR48 WDR48 DSCAML1 DSCAML1 SMPD3 SMPD3 PEX7 PEX7 RARB RARB BARX2 BARX2 HOXB7 HOXB7 FUZ FUZ HOXB1 HOXB1 HOXB8 HOXB8 HOXB5 HOXB5 RAB33B RAB33B NKX3-2 NKX3-2 HOXC11 HOXC11 HOXA9 HOXA9 HOXA4 HOXA4 MEF2D MEF2D A0A4W2I4T2 A0A4W2I4T2 WNT9B WNT9B NOG NOG CSRNP1 CSRNP1 MEF2C MEF2C SOX9 SOX9 LRP5 LRP5 RFLNB RFLNB PRKRA PRKRA SETD2 SETD2 ALX1 ALX1 TBX4 TBX4 IFITM5 IFITM5 BMPR1B BMPR1B HOXC9 HOXC9 SIX1 SIX1 HOXA3 HOXA3 TGFBR2 TGFBR2 RDH10 RDH10 EYA1 EYA1 TRIP11 TRIP11 SULF1 SULF1 IRX5 IRX5 DLG2 DLG2 ACAN ACAN TMEM119 TMEM119 P2RX7 P2RX7 HOXB6 HOXB6 HOXB3 HOXB3 ANKRD11 ANKRD11 IHH IHH EXT1 EXT1 TRPV4 TRPV4 HOXA11 HOXA11 TGFBR1 TGFBR1 A0A4W2CLZ8 A0A4W2CLZ8 FGFR2 FGFR2 SCUBE2 SCUBE2 AXIN2 AXIN2 MDFI MDFI HOXB9 HOXB9 MEGF8 MEGF8 SGPL1 SGPL1 NIPBL NIPBL ACTN3 ACTN3 CSGALNACT1 CSGALNACT1 MMP2 MMP2 MMP16 MMP16 GSC GSC WNT7A WNT7A FLVCR1 FLVCR1 FGF6 FGF6 MTHFD1L MTHFD1L SCX SCX PHOSPHO1 PHOSPHO1 HOXB4 HOXB4 PLEKHA1 PLEKHA1 HHIP HHIP ARID5B ARID5B THRA THRA MED12 MED12 HOXB2 HOXB2 RUNX2 RUNX2 RARA RARA COL13A1 COL13A1 NODAL NODAL HYAL1 HYAL1 HYAL2 HYAL2 GLG1 GLG1 SMAD2 SMAD2 LTF LTF LTBP3 LTBP3 BMP6 BMP6 TFAP2A TFAP2A CTNNB1 CTNNB1 PKD1 PKD1 IFT140 IFT140 WWOX WWOX EIF4A3 EIF4A3 TMEM107 TMEM107 SFRP1 SFRP1 NLE1 NLE1 COL11A2 COL11A2 RAB23 RAB23 HOXA2 HOXA2 PAX5 PAX5 PAPPA2 PAPPA2 CCN2 CCN2 COL2A1 COL2A1 TCF15 TCF15 FMN1 FMN1 HOXC4 HOXC4 SLC39A3 SLC39A3 PSEN1 PSEN1 ALX3 ALX3 SMAD3 SMAD3 MYF5 MYF5 HOXD10 HOXD10 HOXD9 HOXD9 DLX5 DLX5 TIPARP TIPARP TULP3 TULP3 CYP26B1 CYP26B1 BMP4 BMP4 INSIG1 INSIG1 COMP COMP SLC39A1 SLC39A1 BMP7 BMP7 DLX2 DLX2 ZMPSTE24 ZMPSTE24 LOC113892965 LOC113892965 ALPL ALPL TIFAB TIFAB INSIG2 INSIG2 TWIST1 TWIST1 TBXT TBXT THBS3 THBS3 RYK RYK PRRX1 PRRX1 INPPL1 INPPL1 MATN1 MATN1 IMPAD1 IMPAD1 FREM1 FREM1 SP5 SP5 GRHL2 GRHL2 ATF2 ATF2 HOXD4 HOXD4 HOXA5 HOXA5 HOXA7 HOXA7 WDR60 WDR60 EXT2 EXT2 ALX4 ALX4 SIX4 SIX4 PAX1 PAX1 RARG RARG FBN2 FBN2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CHST11Carbohydrate sulfotransferase. (352 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1177 aa)
A0A4W2D3H6Fork-head domain-containing protein. (457 aa)
MMP14Matrix metallopeptidase 14. (582 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa)
CER1Cerberus 1, DAN family BMP antagonist. (273 aa)
OSR1Odd-skipped related transcription factor 1. (267 aa)
SERPINH1Serpin family H member 1; Belongs to the serpin family. (418 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (433 aa)
GLI3GLI family zinc finger 3. (1587 aa)
DHRS3Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (322 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
SDC3Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (603 aa)
NEUROG1Neurogenin 1. (247 aa)
WDR19WD repeat domain 19. (1342 aa)
PPARGC1BPPARG coactivator 1 beta. (1049 aa)
CDX1Caudal type homeobox 1. (265 aa)
NDST1N-deacetylase and N-sulfotransferase 1. (904 aa)
CBSCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (585 aa)
ANXA6Annexin. (751 aa)
A0A4W2F2V6Uncharacterized protein. (122 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
HOXD3Homeobox D3. (434 aa)
SATB2DNA-binding protein SATB. (733 aa)
SFRP4Secreted frizzled related protein 4. (346 aa)
COL1A1Collagen type I alpha 1 chain. (1584 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1098 aa)
FGRTyrosine-protein kinase. (527 aa)
OSR2Odd-skipped related transciption factor 2. (312 aa)
SHOX2Short stature homeobox 2. (331 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
IFT80Intraflagellar transport 80. (781 aa)
NAB2NGFI-A binding protein 2. (525 aa)
OTOROtoraplin. (128 aa)
MSX1Msh homeobox 1. (366 aa)
ZFAND5Zinc finger AN1-type containing 5. (257 aa)
MMP13Matrix metallopeptidase 13. (471 aa)
NPPCNatriuretic peptide C. (193 aa)
RFLNARefilin A. (216 aa)
ATG9AUncharacterized protein. (1498 aa)
TBX15T-box transcription factor 15. (602 aa)
COMMD3RING-type domain-containing protein. (469 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
SIX2SIX homeobox 2. (296 aa)
LHX1LIM homeobox 1. (406 aa)
WDR48WD repeat domain 48. (677 aa)
DSCAML1DS cell adhesion molecule like 1. (2112 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (656 aa)
PEX7Peroxisomal biogenesis factor 7. (323 aa)
RARBRetinoic acid receptor beta. (456 aa)
BARX2BARX homeobox 2. (278 aa)
HOXB7Homeobox B7. (217 aa)
FUZFuzzy planar cell polarity protein. (419 aa)
HOXB1Homeobox B1. (302 aa)
HOXB8Homeobox B8. (243 aa)
HOXB5Homeobox B5. (269 aa)
RAB33BRAB33B, member RAS oncogene family. (229 aa)
NKX3-2NK3 homeobox 2. (330 aa)
HOXC11Homeobox C11. (304 aa)
HOXA9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (272 aa)
HOXA4Homeobox A4. (319 aa)
MEF2DMyocyte enhancer factor 2D. (514 aa)
A0A4W2I4T2Uncharacterized protein. (74 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
CSRNP1Cysteine and serine rich nuclear protein 1. (605 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
SOX9SRY-box transcription factor 9. (524 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1629 aa)
RFLNBRefilin B. (216 aa)
PRKRAProtein activator of interferon induced protein kinase EIF2AK2. (313 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2563 aa)
ALX1ALX homeobox 1. (326 aa)
TBX4T-box transcription factor 4. (550 aa)
IFITM5Interferon induced transmembrane protein 5. (134 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (526 aa)
HOXC9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (260 aa)
SIX1SIX homeobox 1. (284 aa)
HOXA3Homeobox A3. (442 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (700 aa)
TRIP11Thyroid hormone receptor interactor 11. (1976 aa)
SULF1Sulfatase 1. (1109 aa)
IRX5Iroquois homeobox 5. (515 aa)
DLG2Discs large MAGUK scaffold protein 2. (1009 aa)
ACANAggrecan. (2366 aa)
TMEM119Transmembrane protein 119. (287 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
HOXB6Homeobox B6. (224 aa)
HOXB3Homeobox B3. (426 aa)
ANKRD11Ankyrin repeat domain 11. (2575 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (412 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (803 aa)
HOXA11Homeobox A11. (316 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
A0A4W2CLZ8Fork-head domain-containing protein. (225 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
SCUBE2Signal peptide, CUB domain and EGF like domain containing 2. (1027 aa)
AXIN2Axin 2. (836 aa)
MDFIMyoD family inhibitor. (247 aa)
HOXB9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (250 aa)
MEGF8Multiple EGF like domains 8. (2789 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (568 aa)
NIPBLNipped-B protein. (2698 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (901 aa)
CSGALNACT1Hexosyltransferase. (526 aa)
MMP2Matrix metallopeptidase 2. (661 aa)
MMP16Matrix metallopeptidase 16. (607 aa)
GSCGoosecoid homeobox. (266 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
FLVCR1Feline leukemia virus subgroup C cellular receptor 1. (556 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
MTHFD1LMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (976 aa)
SCXScleraxis bHLH transcription factor. (202 aa)
PHOSPHO1Phosphoethanolamine/phosphocholine phosphatase. (334 aa)
HOXB4Homeobox B4. (251 aa)
PLEKHA1Pleckstrin homology domain containing A1. (404 aa)
HHIPHedgehog interacting protein. (701 aa)
ARID5BAT-rich interaction domain 5B. (1181 aa)
THRAThyroid hormone receptor alpha. (520 aa)
MED12Mediator complex subunit 12. (2024 aa)
HOXB2Homeobox B2. (354 aa)
RUNX2RUNX family transcription factor 2. (527 aa)
RARARetinoic acid receptor alpha. (477 aa)
COL13A1Collagen type XIII alpha 1 chain. (751 aa)
NODALNodal growth differentiation factor. (346 aa)
HYAL1Hyaluronidase. (435 aa)
HYAL2Hyaluronidase. (473 aa)
GLG1Golgi glycoprotein 1. (1206 aa)
SMAD2Mothers against decapentaplegic homolog. (626 aa)
LTFLactotransferrin; Belongs to the transferrin family. (726 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1341 aa)
BMP6Bone morphogenetic protein 6. (525 aa)
TFAP2ATranscription factor AP-2 alpha. (439 aa)
CTNNB1Catenin beta 1. (774 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4303 aa)
IFT140Intraflagellar transport 140. (1457 aa)
WWOXWW domain containing oxidoreductase. (490 aa)
EIF4A3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (411 aa)
TMEM107Transmembrane protein 107. (140 aa)
SFRP1Secreted frizzled related protein 1. (307 aa)
NLE1Notchless homolog 1. (488 aa)
COL11A2Collagen type XI alpha 2 chain. (1736 aa)
RAB23RAB23, member RAS oncogene family. (237 aa)
HOXA2Homeobox A2. (372 aa)
PAX5Paired box 5. (391 aa)
PAPPA2Pappalysin 2. (1791 aa)
CCN2Cellular communication network factor 2. (464 aa)
COL2A1Collagen type II alpha 1 chain. (1487 aa)
TCF15Transcription factor 15. (197 aa)
FMN1Formin 1. (1419 aa)
HOXC4Homeobox C4. (265 aa)
SLC39A3Solute carrier family 39 member 3. (314 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (478 aa)
ALX3ALX homeobox 3. (343 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
HOXD10Homeobox D10. (410 aa)
HOXD9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (333 aa)
DLX5Distal-less homeobox 5. (289 aa)
TIPARPTCDD inducible poly(ADP-ribose) polymerase. (656 aa)
TULP3Tubby-like protein; Belongs to the TUB family. (482 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (299 aa)
COMPCartilage oligomeric matrix protein. (756 aa)
SLC39A1Solute carrier family 39 member 1. (324 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
DLX2Distal-less homeobox 2. (331 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
LOC113892965SCHIP-1 domain-containing protein. (554 aa)
ALPLAlkaline phosphatase. (524 aa)
TIFABTIFA inhibitor. (222 aa)
INSIG2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (266 aa)
TWIST1Twist family bHLH transcription factor 1. (201 aa)
TBXTT-box transcription factor T. (435 aa)
THBS3Thrombospondin 3. (998 aa)
RYKReceptor like tyrosine kinase. (626 aa)
PRRX1Paired related homeobox 1. (245 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1264 aa)
MATN1Matrilin 1. (456 aa)
IMPAD1Inositol monophosphatase domain containing 1. (359 aa)
FREM1FRAS1 related extracellular matrix 1. (2180 aa)
SP5Sp5 transcription factor. (397 aa)
GRHL2Grainyhead like transcription factor 2. (609 aa)
ATF2Activating transcription factor 2. (447 aa)
HOXD4Homeobox D4. (257 aa)
HOXA5Homeobox A5. (381 aa)
HOXA7Homeobox A7. (238 aa)
WDR60WD repeat domain 60. (1135 aa)
EXT2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (751 aa)
ALX4ALX homeobox 4. (397 aa)
SIX4SIX homeobox 4. (786 aa)
PAX1Paired box 1. (593 aa)
RARGRetinoic acid receptor gamma. (519 aa)
FBN2Fibrillin 2. (2912 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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