STRINGSTRING
PRKN PRKN PLG PLG DNAJB5 DNAJB5 GNB5 GNB5 RNF207 RNF207 SDF2L1 SDF2L1 DNAJC1 DNAJC1 CFTR CFTR DNAJB13 DNAJB13 DNAJB7 DNAJB7 TERT TERT A0A4W2CBM9 A0A4W2CBM9 LOC113901342 LOC113901342 CDC25A CDC25A WRAP53 WRAP53 AMFR AMFR GET4 GET4 HSPD1 HSPD1 A0A4W2C633 A0A4W2C633 DNAJA4 DNAJA4 KSR1 KSR1 VWF VWF BAG3 BAG3 SACS SACS SLC25A17 SLC25A17 A0A4W2BZZ1 A0A4W2BZZ1 PFDN6 PFDN6 BAG2 BAG2 DNLZ DNLZ SUGT1 SUGT1 CDKN1B CDKN1B HSPB6 HSPB6 DNAJC3 DNAJC3 STUB1 STUB1 ERP29 ERP29 TIMM10 TIMM10 DNAJA1 DNAJA1 ATP1A1 ATP1A1 ATP1A2 ATP1A2 ATP1A3 ATP1A3 SYVN1 SYVN1 PTGES3 PTGES3 DNAJB8 DNAJB8 BAG4 BAG4 DNAJB4 DNAJB4 A0A4W2F3K6 A0A4W2F3K6 A0A4W2F3J4 A0A4W2F3J4 HSPD1-2 HSPD1-2 BIN1 BIN1 LOC113893980 LOC113893980 A0A4W2EWG4 A0A4W2EWG4 A0A4W2EU57 A0A4W2EU57 SLC12A2 SLC12A2 AHSA1 AHSA1 TIMM44 TIMM44 DNAJB2 DNAJB2 A0A4W2EDB7 A0A4W2EDB7 PTGES3L PTGES3L GRN GRN A0A4W2E888 A0A4W2E888 PDPN PDPN FN1 FN1 DNAJB9 DNAJB9 FICD FICD BAG5 BAG5 FNIP2 FNIP2 CDC37 CDC37 DNAJB1 DNAJB1 DNAJC12 DNAJC12 DNAJA2 DNAJA2 CP CP LRP2 LRP2 SCARB2 SCARB2 TSC1 TSC1 DNAJC9 DNAJC9 FNIP1 FNIP1 GRPEL1 GRPEL1 HES1 HES1 PACRGL PACRGL PACRG PACRG DNAJC13 DNAJC13 GRPEL2 GRPEL2 TSACC TSACC A0A4W2DDG6 A0A4W2DDG6 A0A4W2DCT1 A0A4W2DCT1 A0A4W2DCQ8 A0A4W2DCQ8 ALB ALB BAG1 BAG1 DNAJB6 DNAJB6 A0A4W2D3N8 A0A4W2D3N8 FGB FGB TP53 TP53 CDC37L1 CDC37L1 USP13 USP13 CNPY2 CNPY2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (460 aa)
PLGPlasminogen; Belongs to the peptidase S1 family. (849 aa)
DNAJB5DnaJ heat shock protein family (Hsp40) member B5. (420 aa)
GNB5G protein subunit beta 5. (452 aa)
RNF207Ring finger protein 207. (633 aa)
SDF2L1Stromal cell derived factor 2 like 1. (318 aa)
DNAJC1DnaJ heat shock protein family (Hsp40) member C1. (542 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1481 aa)
DNAJB13DnaJ heat shock protein family (Hsp40) member B13. (316 aa)
DNAJB7DnaJ heat shock protein family (Hsp40) member B7. (304 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1125 aa)
A0A4W2CBM9Ubiquitin-like domain-containing protein. (201 aa)
LOC113901342Aha1_N domain-containing protein. (502 aa)
CDC25ACell division cycle 25A. (525 aa)
WRAP53WD repeat containing antisense to TP53. (540 aa)
AMFRAutocrine motility factor receptor. (758 aa)
GET4Guided entry of tail-anchored proteins factor 4. (422 aa)
HSPD1Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (573 aa)
A0A4W2C633Uncharacterized protein. (4359 aa)
DNAJA4DnaJ heat shock protein family (Hsp40) member A4. (549 aa)
KSR1Kinase suppressor of ras 1. (928 aa)
VWFVon Willebrand factor. (2810 aa)
BAG3BCL2 associated athanogene 3. (585 aa)
SACSSacsin molecular chaperone. (4595 aa)
SLC25A17Solute carrier family 25 member 17; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa)
A0A4W2BZZ1CR-type domain-containing protein. (172 aa)
PFDN6Prefoldin subunit 6. (129 aa)
BAG2BCL2 associated athanogene 2. (211 aa)
DNLZDNL-type zinc finger. (236 aa)
SUGT1SGT1 homolog, MIS12 kinetochore complex assembly cochaperone. (333 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
HSPB6Heat shock protein family B (small) member 6; Belongs to the small heat shock protein (HSP20) family. (235 aa)
DNAJC3DnaJ heat shock protein family (Hsp40) member C3. (504 aa)
STUB1Uncharacterized protein. (592 aa)
ERP29Endoplasmic reticulum resident protein 29; Does not seem to be a disulfide isomerase. (258 aa)
TIMM10Translocase of inner mitochondrial membrane 10. (90 aa)
DNAJA1Uncharacterized protein. (397 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1021 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1048 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
SYVN1Synoviolin 1. (611 aa)
PTGES3CS domain-containing protein. (160 aa)
DNAJB8DnaJ heat shock protein family (Hsp40) member B8. (231 aa)
BAG4BCL2 associated athanogene 4. (457 aa)
DNAJB4DnaJ heat shock protein family (Hsp40) member B4. (337 aa)
A0A4W2F3K6Uncharacterized protein; Belongs to the GroES chaperonin family. (283 aa)
A0A4W2F3J4J domain-containing protein. (112 aa)
HSPD1-2Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (569 aa)
BIN1Bridging integrator 1. (602 aa)
LOC113893980Uncharacterized protein; Belongs to the multicopper oxidase family. (1043 aa)
A0A4W2EWG4J domain-containing protein. (183 aa)
A0A4W2EU57DUF3456 domain-containing protein. (256 aa)
SLC12A2Solute carrier family 12 member 2. (1204 aa)
AHSA1Activator of HSP90 ATPase activity 1. (338 aa)
TIMM44Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (459 aa)
DNAJB2DnaJ heat shock protein family (Hsp40) member B2. (325 aa)
A0A4W2EDB7Uncharacterized protein; Belongs to the GroES chaperonin family. (101 aa)
PTGES3LProstaglandin E synthase 3 like. (159 aa)
GRNGranulin precursor. (663 aa)
A0A4W2E888CS domain-containing protein. (167 aa)
PDPNUncharacterized protein. (169 aa)
FN1Fibronectin 1. (2601 aa)
DNAJB9DnaJ heat shock protein family (Hsp40) member B9. (223 aa)
FICDFIC domain containing. (536 aa)
BAG5BCL2 associated athanogene 5. (447 aa)
FNIP2Folliculin interacting protein 2. (1110 aa)
CDC37Cell division cycle 37. (380 aa)
DNAJB1DnaJ heat shock protein family (Hsp40) member B1. (340 aa)
DNAJC12DnaJ heat shock protein family (Hsp40) member C12. (226 aa)
DNAJA2Uncharacterized protein. (412 aa)
CPCeruloplasmin; Belongs to the multicopper oxidase family. (1089 aa)
LRP2LDL receptor related protein 2. (4647 aa)
SCARB2Scavenger receptor class B member 2; Belongs to the CD36 family. (520 aa)
TSC1TSC complex subunit 1. (1165 aa)
DNAJC9DnaJ heat shock protein family (Hsp40) member C9. (260 aa)
FNIP1Folliculin interacting protein 1. (1163 aa)
GRPEL1GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (217 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
PACRGLParkin coregulated like. (264 aa)
PACRGParkin coregulated. (257 aa)
DNAJC13DnaJ heat shock protein family (Hsp40) member C13. (2262 aa)
GRPEL2GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (224 aa)
TSACCTSSK6 activating cochaperone. (129 aa)
A0A4W2DDG6DnaJ_C domain-containing protein. (237 aa)
A0A4W2DCT1J domain-containing protein. (100 aa)
A0A4W2DCQ8Uncharacterized protein; Belongs to the GrpE family. (217 aa)
ALBAlbumin. (655 aa)
BAG1Uncharacterized protein. (328 aa)
DNAJB6DnaJ heat shock protein family (Hsp40) member B6. (364 aa)
A0A4W2D3N8J domain-containing protein. (182 aa)
FGBFibrinogen beta chain. (490 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (499 aa)
CDC37L1Cell division cycle 37 like 1. (337 aa)
USP13Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (863 aa)
CNPY2Saposin B-type domain-containing protein. (182 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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