59 items (Bos indicus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

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Your Input:
	SLC9A2	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (809 aa)
	ATP6V0A4	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (834 aa)
	SLC9C1	Solute carrier family 9 member C1. (1145 aa)
	CLN6	CLN6 transmembrane ER protein. (380 aa)
	DMXL1	Dmx like 1. (3083 aa)
	TMEM175	Transmembrane protein 175. (585 aa)
	TMEM165	GDT1 family protein. (324 aa)
	SLC4A4	Anion exchange protein. (1190 aa)
	SLC9A7	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (731 aa)
	ATP6V1B1	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
	SNAPIN	SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
	CA7	Carbonic anhydrase 7; Belongs to the alpha-carbonic anhydrase family. (264 aa)
	CLIC4	Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa)
	CA2	Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family. (260 aa)
	CLN5	Uncharacterized protein. (358 aa)
	RAB38	RAB38, member RAS oncogene family. (211 aa)
	ATP6AP2	Uncharacterized protein. (377 aa)
	LRRK2	Leucine rich repeat kinase 2. (2527 aa)
	SLC4A8	Anion exchange protein. (1092 aa)
	SLC9A8	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (597 aa)
	SLC4A2	Anion exchange protein. (1276 aa)
	GPR89A	Uncharacterized protein. (544 aa)
	CLN3	Battenin. (460 aa)
	RAB7A	RAB7A, member RAS oncogene family. (207 aa)
	SLC4A7	Anion exchange protein. (1241 aa)
	BCL2	BCL2 apoptosis regulator. (229 aa)
	ATP6V0D1	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
	SLC26A6	Solute carrier family 26 member 6. (763 aa)
	SLC4A1	Anion exchange protein. (1059 aa)
	TCIRG1	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
	ATP6V0A2	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (853 aa)
	ATP6V0A1	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (839 aa)
	SLC9A3	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (835 aa)
	CFTR	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1481 aa)
	SLC11A1	Solute carrier family 11 member 1. (601 aa)
	SLC4A5	Anion exchange protein. (1142 aa)
	SLC4A3	Anion exchange protein. (1226 aa)
	RAB20	RAB20, member RAS oncogene family. (231 aa)
	SLC9A1	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (818 aa)
	SLC4A10	Anion exchange protein. (1147 aa)
	PPT1	Uncharacterized protein. (336 aa)
	SLC9A5	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (900 aa)
	RAB39A	RAB39A, member RAS oncogene family. (217 aa)
	ATP6V1B2	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (511 aa)
	TM9SF4	Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (642 aa)
	SLC9A9	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (640 aa)
	SLC26A3	Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (760 aa)
	AQP11	Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (271 aa)
	TMEM199	Transmembrane protein 199. (268 aa)
	TMEM9	Transmembrane protein 9. (181 aa)
	SLC4A9	Anion exchange protein. (957 aa)
	A0A4W2E9C1	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (596 aa)
	GRN	Granulin precursor. (663 aa)
	SLC9A4	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (797 aa)
	UBE3A	Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (875 aa)
	ATP6V0D2	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
	CHP1	Calcineurin like EF-hand protein 1. (195 aa)
	ATP5F1B	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa)
	DMXL2	Dmx like 2. (3036 aa)

Your Current Organism:

Bos indicus

NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AQP11	SLC4A5	A0A4W2DM69	A0A4W2CMI7	Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.	Anion exchange protein.	0.479
ATP5F1B	ATP6V0A1	A0A4W2EL77	A0A4W2CHA9	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.400
ATP5F1B	ATP6V0A2	A0A4W2EL77	A0A4W2CDD0	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.477
ATP5F1B	ATP6V1B1	A0A4W2EL77	A0A4W2FAZ5	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.736
ATP5F1B	ATP6V1B2	A0A4W2EL77	A0A4W2IIU8	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.736
ATP6AP2	ATP6V0A1	A0A4W2HWP1	A0A4W2CHA9	Uncharacterized protein.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.991
ATP6AP2	ATP6V0A2	A0A4W2HWP1	A0A4W2CDD0	Uncharacterized protein.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.654
ATP6AP2	ATP6V0A4	A0A4W2HWP1	A0A4W2EM57	Uncharacterized protein.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.784
ATP6AP2	ATP6V0D1	A0A4W2HWP1	A0A4W2CAX3	Uncharacterized protein.	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	0.997
ATP6AP2	ATP6V0D2	A0A4W2HWP1	A0A4W2EIW7	Uncharacterized protein.	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	0.872
ATP6AP2	ATP6V1B1	A0A4W2HWP1	A0A4W2FAZ5	Uncharacterized protein.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.917
ATP6AP2	ATP6V1B2	A0A4W2HWP1	A0A4W2IIU8	Uncharacterized protein.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.946
ATP6AP2	TCIRG1	A0A4W2HWP1	A0A4W2CCQ8	Uncharacterized protein.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.602
ATP6V0A1	ATP5F1B	A0A4W2CHA9	A0A4W2EL77	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.	0.400
ATP6V0A1	ATP6AP2	A0A4W2CHA9	A0A4W2HWP1	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Uncharacterized protein.	0.991
ATP6V0A1	ATP6V0A2	A0A4W2CHA9	A0A4W2CDD0	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.977
ATP6V0A1	ATP6V0A4	A0A4W2CHA9	A0A4W2EM57	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.966
ATP6V0A1	ATP6V0D1	A0A4W2CHA9	A0A4W2CAX3	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	0.999
ATP6V0A1	ATP6V0D2	A0A4W2CHA9	A0A4W2EIW7	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	0.998
ATP6V0A1	ATP6V1B1	A0A4W2CHA9	A0A4W2FAZ5	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.991

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