(72 nodes) Regulation of stress fiber assembly network (Bos indicus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	FERMT2	Fermitin family member 2. (706 aa)
	CGNL1	Cingulin like 1. (1293 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
	CARMIL1	Capping protein regulator and myosin 1 linker 1. (1426 aa)
	ARHGEF10	Rho guanine nucleotide exchange factor 10. (1366 aa)
	RHPN1	Rhophilin Rho GTPase binding protein 1. (729 aa)
	DLC1	DLC1 Rho GTPase activating protein. (1169 aa)
	MYOC	Myocilin. (490 aa)
	ARHGEF15	Rho guanine nucleotide exchange factor 15. (847 aa)
	MET	MET proto-oncogene, receptor tyrosine kinase. (1384 aa)
	ITGB1BP1	Integrin subunit beta 1 binding protein 1. (200 aa)
	A0A4W2EBL9	Uncharacterized protein. (1267 aa)
	TESK1	Testis associated actin remodelling kinase 1. (630 aa)
	PPM1E	Protein phosphatase, Mg2+/Mn2+ dependent 1E. (754 aa)
	NRP1	Neuropilin; Belongs to the neuropilin family. (923 aa)
	RHPN2	Rhophilin Rho GTPase binding protein 2. (686 aa)
	SFRP1	Secreted frizzled related protein 1. (307 aa)
	ARHGEF10L	Rho guanine nucleotide exchange factor 10 like. (1120 aa)
	ARHGAP28	Rho GTPase activating protein 28. (755 aa)
	TSC1	TSC complex subunit 1. (1165 aa)
	SERPINF2	Serpin family F member 2; Belongs to the serpin family. (492 aa)
	LIMK1	LIM domain kinase 1. (778 aa)
	A0A4W2DQB1	Coronin; Belongs to the WD repeat coronin family. (262 aa)
	WAS	WASP actin nucleation promoting factor. (559 aa)
	INPP5K	Inositol polyphosphate-5-phosphatase K. (449 aa)
	PAK2	Non-specific serine/threonine protein kinase. (600 aa)
	ARHGEF18	Uncharacterized protein. (1345 aa)
	LIMCH1	LIM and calponin homology domains 1. (1570 aa)
	CDC42	Cell division cycle 42. (191 aa)
	PPM1F	Protein phosphatase, Mg2+/Mn2+ dependent 1F. (672 aa)
	SORBS3	Sorbin and SH3 domain containing 3. (783 aa)
	ASAP3	ArfGAP with SH3 domain, ankyrin repeat and PH domain 3. (883 aa)
	TACSTD2	Tumor associated calcium signal transducer 2. (319 aa)
	SYNPO	Synaptopodin. (1131 aa)
	TMEFF2	Transmembrane protein with EGF like and two follistatin like domains 2. (429 aa)
	WASF2	WASP family member 2. (493 aa)
	BAG4	BCL2 associated athanogene 4. (457 aa)
	RHOA	Ras homolog family member A. (193 aa)
	EPHA1	EPH receptor A1. (1076 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (452 aa)
	LPAR1	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
	GPR65	G protein-coupled receptor 65; Belongs to the G-protein coupled receptor 1 family. (334 aa)
	BRAF	B-Raf proto-oncogene, serine/threonine kinase. (805 aa)
	ARAP1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1. (1740 aa)
	CCN2	Cellular communication network factor 2. (464 aa)
	PIK3R2	Uncharacterized protein. (724 aa)
	TTC8	Tetratricopeptide repeat domain 8. (501 aa)
	F11R	F11 receptor. (298 aa)
	FHOD1	Formin homology 2 domain containing 1. (1228 aa)
	STMN1	Uncharacterized protein. (295 aa)
	CORO2B	Coronin; Belongs to the WD repeat coronin family. (503 aa)
	PFN2	Profilin; Belongs to the profilin family. (142 aa)
	NF2	Neurofibromin 2. (596 aa)
	PAK1	Non-specific serine/threonine protein kinase. (544 aa)
	CORO2A	Coronin; Belongs to the WD repeat coronin family. (581 aa)
	S100A10	S100 calcium binding protein A10; Belongs to the S-100 family. (97 aa)
	ARHGEF5	Rho guanine nucleotide exchange factor 5. (1655 aa)
	A0A4W2BMR3	Rho-GAP domain-containing protein. (263 aa)
	ALMS1	ALMS1 centrosome and basal body associated protein. (4304 aa)
	EVL	Enah/Vasp-like. (455 aa)
	TGFBR1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
	CCDC88A	Coiled-coil domain containing 88A. (1842 aa)
	WNT11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	PTGER4	Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (492 aa)
	MKKS	McKusick-Kaufman syndrome. (570 aa)
	RHOC	Ras homolog family member C. (193 aa)
	BBS4	Bardet-Biedl syndrome 4. (519 aa)
	PHLDB2	Pleckstrin homology like domain family B member 2. (1343 aa)
	RAPGEF3	Rap guanine nucleotide exchange factor 3. (923 aa)
	ROCK2	Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1469 aa)
	ABL1	Tyrosine-protein kinase. (1151 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)

Your Current Organism:

Bos indicus

NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A4W2BMR3	CDC42	A0A4W2BMR3	A0A4W2DEW8	Rho-GAP domain-containing protein.	Cell division cycle 42.	0.596
A0A4W2BMR3	RHOA	A0A4W2BMR3	A0A4W2FLL1	Rho-GAP domain-containing protein.	Ras homolog family member A.	0.581
A0A4W2BMR3	RHOC	A0A4W2BMR3	A0A4W2D3R3	Rho-GAP domain-containing protein.	Ras homolog family member C.	0.497
A0A4W2EBL9	BAG4	A0A4W2EBL9	A0A4W2FF81	Uncharacterized protein.	BCL2 associated athanogene 4.	0.424
A0A4W2EBL9	PHLDB2	A0A4W2EBL9	A0A4W2D084	Uncharacterized protein.	Pleckstrin homology like domain family B member 2.	0.499
ABL1	CDC42	A0A4W2CTP7	A0A4W2DEW8	Tyrosine-protein kinase.	Cell division cycle 42.	0.503
ABL1	EPHA1	A0A4W2CTP7	A0A4W2ES08	Tyrosine-protein kinase.	EPH receptor A1.	0.917
ABL1	EVL	A0A4W2CTP7	A0A4W2CPE0	Tyrosine-protein kinase.	Enah/Vasp-like.	0.676
ALMS1	BBS4	A0A4W2CQL7	A0A4W2D313	ALMS1 centrosome and basal body associated protein.	Bardet-Biedl syndrome 4.	0.416
ARAP1	ARHGEF18	A0A4W2EK28	A0A4W2DHU4	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1.	Uncharacterized protein.	0.440
ARAP1	CDC42	A0A4W2EK28	A0A4W2DEW8	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1.	Cell division cycle 42.	0.455
ARAP1	PPM1E	A0A4W2EK28	A0A4W2E9D0	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1.	Protein phosphatase, Mg2+/Mn2+ dependent 1E.	0.587
ARHGAP28	RHOA	A0A4W2DVS7	A0A4W2FLL1	Rho GTPase activating protein 28.	Ras homolog family member A.	0.403
ARHGAP28	RHOC	A0A4W2DVS7	A0A4W2D3R3	Rho GTPase activating protein 28.	Ras homolog family member C.	0.403
ARHGEF10	CDC42	A0A4W2C3J4	A0A4W2DEW8	Rho guanine nucleotide exchange factor 10.	Cell division cycle 42.	0.435
ARHGEF10	RHOA	A0A4W2C3J4	A0A4W2FLL1	Rho guanine nucleotide exchange factor 10.	Ras homolog family member A.	0.403
ARHGEF15	CDC42	A0A4W2EGT1	A0A4W2DEW8	Rho guanine nucleotide exchange factor 15.	Cell division cycle 42.	0.403
ARHGEF18	ARAP1	A0A4W2DHU4	A0A4W2EK28	Uncharacterized protein.	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1.	0.440
ARHGEF18	CDC42	A0A4W2DHU4	A0A4W2DEW8	Uncharacterized protein.	Cell division cycle 42.	0.437
ARHGEF18	CGNL1	A0A4W2DHU4	A0A4W2CRB0	Uncharacterized protein.	Cingulin like 1.	0.476

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