STRINGSTRING
PHLDA3 PHLDA3 SLC9A3R1 SLC9A3R1 DRD2 DRD2 PKHD1 PKHD1 PHLPP1 PHLPP1 HYAL2 HYAL2 DAG1 DAG1 TSC2 TSC2 DDIT3 DDIT3 DLG1 DLG1 CAVIN3 CAVIN3 RAPGEF1 RAPGEF1 INPP5K INPP5K SIRT1 SIRT1 PIK3CB PIK3CB GPER1 GPER1 PPARA PPARA SH2B3 SH2B3 SFRP5 SFRP5 DLG2 DLG2 PTPRJ PTPRJ OTUD3 OTUD3 MUL1 MUL1 EPHA2 EPHA2 BANK1 BANK1 MSTN MSTN FLCN FLCN LEMD2 LEMD2 PPP2CA PPP2CA CIB1 CIB1 PLEKHA1 PLEKHA1 NOP53 NOP53 A0A4W2CIL9 A0A4W2CIL9 XDH XDH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PHLDA3Pleckstrin homology like domain family A member 3. (123 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (368 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
PKHD1PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (4060 aa)
PHLPP1PH domain and leucine rich repeat protein phosphatase 1. (1503 aa)
HYAL2Hyaluronidase. (473 aa)
DAG1Dystroglycan 1. (1096 aa)
TSC2TSC complex subunit 2. (1887 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa)
CAVIN3Caveolae associated protein 3. (260 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1265 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (449 aa)
SIRT1Sirtuin 1. (734 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
PPARAPeroxisome proliferator activated receptor alpha. (470 aa)
SH2B3SH2B adaptor protein 3. (587 aa)
SFRP5Secreted frizzled related protein 5. (315 aa)
DLG2Discs large MAGUK scaffold protein 2. (1009 aa)
PTPRJPeptidylprolyl isomerase. (1344 aa)
OTUD3OTU deubiquitinase 3. (397 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (350 aa)
EPHA2EPH receptor A2. (1007 aa)
BANK1B cell scaffold protein with ankyrin repeats 1. (781 aa)
MSTNMyostatin. (375 aa)
FLCNUDENN FLCN/SMCR8-type domain-containing protein. (579 aa)
LEMD2LEM domain containing 2. (495 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
CIB1Calcium and integrin binding 1. (191 aa)
PLEKHA1Pleckstrin homology domain containing A1. (404 aa)
NOP53NOP53 ribosome biogenesis factor. (534 aa)
A0A4W2CIL9Uncharacterized protein. (423 aa)
XDHXanthine dehydrogenase. (1332 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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