14 items (Bos indicus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BMP4	Bone morphogenetic protein 4. (409 aa)
	TP63	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
	HIF1A	Hypoxia inducible factor 1 subunit alpha. (842 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
	NODAL	Nodal growth differentiation factor. (346 aa)
	AR	Androgen receptor. (889 aa)
	CECR2	CECR2 histone acetyl-lysine reader. (1375 aa)
	HOXD13	Homeobox D13. (341 aa)
	BMP7	Bone morphogenetic protein 7. (431 aa)
	GDF7	Growth differentiation factor 7. (411 aa)
	LUZP1	Leucine zipper protein 1. (1070 aa)
	RDH10	Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
	SOSTDC1	Sclerostin domain containing 1. (228 aa)

Your Current Organism:

Bos indicus

NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AR	HIF1A	A0A4W2BYM9	A0A4W2HED4	Androgen receptor.	Hypoxia inducible factor 1 subunit alpha.	0.498
BMP4	BMP7	A0A4W2EH28	A0A4W2DCR7	Bone morphogenetic protein 4.	Bone morphogenetic protein 7.	0.772
BMP4	FGF10	A0A4W2EH28	A0A4W2HK43	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.753
BMP4	NODAL	A0A4W2EH28	A0A4W2BWB9	Bone morphogenetic protein 4.	Nodal growth differentiation factor.	0.422
BMP4	NOG	A0A4W2EH28	A0A4W2IEW3	Bone morphogenetic protein 4.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.948
BMP7	BMP4	A0A4W2DCR7	A0A4W2EH28	Bone morphogenetic protein 7.	Bone morphogenetic protein 4.	0.772
BMP7	FGF10	A0A4W2DCR7	A0A4W2HK43	Bone morphogenetic protein 7.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.470
BMP7	GDF7	A0A4W2DCR7	A0A4W2DFD8	Bone morphogenetic protein 7.	Growth differentiation factor 7.	0.875
BMP7	NOG	A0A4W2DCR7	A0A4W2IEW3	Bone morphogenetic protein 7.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.931
FGF10	BMP4	A0A4W2HK43	A0A4W2EH28	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Bone morphogenetic protein 4.	0.753
FGF10	BMP7	A0A4W2HK43	A0A4W2DCR7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Bone morphogenetic protein 7.	0.470
FGF10	HIF1A	A0A4W2HK43	A0A4W2HED4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Hypoxia inducible factor 1 subunit alpha.	0.413
FGF10	NOG	A0A4W2HK43	A0A4W2IEW3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.574
GDF7	BMP7	A0A4W2DFD8	A0A4W2DCR7	Growth differentiation factor 7.	Bone morphogenetic protein 7.	0.875
GDF7	NOG	A0A4W2DFD8	A0A4W2IEW3	Growth differentiation factor 7.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.816
HIF1A	AR	A0A4W2HED4	A0A4W2BYM9	Hypoxia inducible factor 1 subunit alpha.	Androgen receptor.	0.498
HIF1A	FGF10	A0A4W2HED4	A0A4W2HK43	Hypoxia inducible factor 1 subunit alpha.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.413
NODAL	BMP4	A0A4W2BWB9	A0A4W2EH28	Nodal growth differentiation factor.	Bone morphogenetic protein 4.	0.422
NOG	BMP4	A0A4W2IEW3	A0A4W2EH28	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	Bone morphogenetic protein 4.	0.948
NOG	BMP7	A0A4W2IEW3	A0A4W2DCR7	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	Bone morphogenetic protein 7.	0.931

page 1 of 2

Server load: low (20%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2025

Credits

Access

Info

About