STRINGSTRING
A0A4W2EG68 A0A4W2EG68 SREBF1 SREBF1 TNF TNF APOB APOB A0A4W2ECP6 A0A4W2ECP6 BRCA1 BRCA1 A0A4W2EBW4 A0A4W2EBW4 C1QTNF3 C1QTNF3 FMO2 FMO2 VCP VCP ATPSCKMT ATPSCKMT STAT3 STAT3 SNAI1 SNAI1 DKK3 DKK3 NCOR2 NCOR2 NR1H2 NR1H2 ATP2B4 ATP2B4 A0A4W2E5D6 A0A4W2E5D6 SEC14L2 SEC14L2 GNB3 GNB3 MALRD1 MALRD1 C1QTNF1 C1QTNF1 PPP4R3B PPP4R3B KAT2A KAT2A PPTC7 PPTC7 PDK2 PDK2 P2RX7 P2RX7 DDIT4 DDIT4 APP APP PPARA PPARA SIRT4 SIRT4 GPLD1 GPLD1 GPER1 GPER1 PROX1 PROX1 NCOR1 NCOR1 KCNMA1 KCNMA1 ELOVL5 ELOVL5 GIP GIP NOS2 NOS2 SIRT1 SIRT1 SCAP SCAP CLYBL CLYBL PANK2 PANK2 IRS2 IRS2 DYRK2 DYRK2 PARP1 PARP1 PRKN PRKN LEP LEP APOE APOE SPHK2 SPHK2 GFI1 GFI1 NCOA2 NCOA2 NOS3 NOS3 FBP1 FBP1 PLIN5 PLIN5 SLC7A7 SLC7A7 FGFR4 FGFR4 MIDN MIDN FMO3 FMO3 INSIG1 INSIG1 REST REST PDK1 PDK1 FGF1 FGF1 WDTC1 WDTC1 ZMPSTE24 ZMPSTE24 TTC39B TTC39B DUSP12 DUSP12 LEPR LEPR INSIG2 INSIG2 A0A4W2DH90 A0A4W2DH90 TWIST1 TWIST1 A0A4W2DHM0 A0A4W2DHM0 EGR1 EGR1 DNM1L DNM1L SIRT6 SIRT6 ZBTB7A ZBTB7A APPL2 APPL2 BCKDK BCKDK A0A4W2DM58 A0A4W2DM58 CLCN2 CLCN2 USP7 USP7 A0A4W2BLA5 A0A4W2BLA5 SEC14L5 SEC14L5 A0A4W2BND6 A0A4W2BND6 GIT1 GIT1 MLXIPL MLXIPL CLN3 CLN3 JMJD8 JMJD8 A0A4W2BQI8 A0A4W2BQI8 MID1IP1 MID1IP1 FOXO1 FOXO1 SIRT5 SIRT5 A0A4W2BS45 A0A4W2BS45 BMP6 BMP6 DDB1 DDB1 PTPN2 PTPN2 SLC2A6 SLC2A6 COX11 COX11 PDZD3 PDZD3 A0A4W2BWV5 A0A4W2BWV5 NR1D1 NR1D1 SLC7A11 SLC7A11 APOA5 APOA5 MST1 MST1 TYSND1 TYSND1 IGFBP4 IGFBP4 BMP5 BMP5 EP300 EP300 ARV1 ARV1 OGT OGT A0A4W2C1F6 A0A4W2C1F6 PLA2G3 PLA2G3 SEC14L4 SEC14L4 GNMT GNMT GUCA1B GUCA1B A0A4W2C5I5 A0A4W2C5I5 A0A4W2C692 A0A4W2C692 FOXK1 FOXK1 LPGAT1 LPGAT1 NOS1 NOS1 LCMT1 LCMT1 BAD BAD A0A4W2C9G4 A0A4W2C9G4 LONP2 LONP2 NLN NLN ACTN3 ACTN3 SLC4A1 SLC4A1 APOC3 APOC3 APOA4 APOA4 A0A4W2CD20 A0A4W2CD20 PMAIP1 PMAIP1 BEND3 BEND3 P2RY6 P2RY6 AVPR1B AVPR1B RANBP2 RANBP2 PRKCE PRKCE AKT2 AKT2 CAV1 CAV1 LHCGR LHCGR INMT INMT A0A4W2CRW3 A0A4W2CRW3 SERPINA12 SERPINA12 CBFA2T3 CBFA2T3 PTH PTH LPCAT3 LPCAT3 FABP5 FABP5 WDR5 WDR5 ACACB ACACB A0A4W2CP79 A0A4W2CP79 GEMIN6 GEMIN6 ENO1 ENO1 RORA RORA FAM3C FAM3C SOX9 SOX9 INSR INSR SLC35B4 SLC35B4 ADIPOQ ADIPOQ FGF19 FGF19 RD3 RD3 CRY1 CRY1 FMO1 FMO1 NFKB1 NFKB1 TIGAR TIGAR IGF1 IGF1 CYP7A1 CYP7A1 TP53 TP53 ADIPOR1 ADIPOR1 IGFBP3 IGFBP3 A0A4W2HWU9 A0A4W2HWU9 FOXK2 FOXK2 PRKAG2 PRKAG2 ATCAY ATCAY PDK4 PDK4 ATP5IF1 ATP5IF1 HIF1A HIF1A PGP PGP STARD4 STARD4 PIBF1 PIBF1 GUCA1A GUCA1A MLYCD MLYCD LOC113893369 LOC113893369 DKKL1 DKKL1 ABCG4 ABCG4 ZNF692 ZNF692 PTGS2 PTGS2 SNAI2 SNAI2 NUPR1 NUPR1 HTR2A HTR2A GCG GCG AK4-2 AK4-2 PRMT3 PRMT3 EPM2AIP1 EPM2AIP1 APOC2 APOC2 CD74 CD74 SNCA SNCA NR1H3 NR1H3 NR1H4 NR1H4 GCK GCK PID1 PID1 BMP2 BMP2 C1QTNF12 C1QTNF12 ZBTB20 ZBTB20 PPARD PPARD AKT1 AKT1 FLCN FLCN SLC45A3 SLC45A3 CYP27B1 CYP27B1 PRL PRL TREM2 TREM2 DNAJC30 DNAJC30 NKX1-1 NKX1-1 KAT2B KAT2B A0A4W2F478 A0A4W2F478 LDLR LDLR CYP27C1 CYP27C1 SIK1 SIK1 ACMSD ACMSD A0A4W2F1T9 A0A4W2F1T9 ETFBKMT ETFBKMT C1QTNF6 C1QTNF6 NR3C1 NR3C1 TTC39A TTC39A PPARGC1A PPARGC1A A0A4W2EWY4 A0A4W2EWY4 GUCA2B GUCA2B SLC4A4 SLC4A4 A0A4W2EW96 A0A4W2EW96 ABCB11 ABCB11 MFSD2A MFSD2A ERFE ERFE A0A4W2EVH5 A0A4W2EVH5 A0A4W2EUX9 A0A4W2EUX9 EPHX2 EPHX2 PTK2B PTK2B FMO5 FMO5 PRXL2C PRXL2C PSEN1 PSEN1 A0A4W2EQN1 A0A4W2EQN1 PLEK PLEK GPD1 GPD1 EIF6 EIF6 SLC27A4 SLC27A4 H6PD H6PD PARK7 PARK7 A0A4W2EJS8 A0A4W2EJS8 IL1B IL1B ABCD2 ABCD2 TRIB3 TRIB3 FMO4 FMO4 SIRT7 SIRT7 ACADVL ACADVL IFNG IFNG NCS1 NCS1 SEC14L3 SEC14L3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A4W2EG68Uncharacterized protein. (347 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1146 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (333 aa)
APOBApolipoprotein B. (4567 aa)
A0A4W2ECP6Uncharacterized protein. (141 aa)
BRCA1BRCA1 DNA repair associated. (1941 aa)
A0A4W2EBW4CCDC144C domain-containing protein. (326 aa)
C1QTNF3C1q domain-containing protein. (319 aa)
FMO2Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (816 aa)
ATPSCKMTATP synthase c subunit lysine N-methyltransferase. (221 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
DKK3Dickkopf WNT signaling pathway inhibitor 3. (458 aa)
NCOR2Nuclear receptor corepressor 2. (2101 aa)
NR1H2Nuclear receptor subfamily 1 group H member 2. (455 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1207 aa)
A0A4W2E5D6Uncharacterized protein. (144 aa)
SEC14L2Uncharacterized protein. (403 aa)
GNB3G protein subunit beta 3. (356 aa)
MALRD1MAM and LDL receptor class A domain containing 1. (2180 aa)
C1QTNF1C1q and TNF related 1. (279 aa)
PPP4R3BProtein phosphatase 4 regulatory subunit 3B. (820 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
PPTC7Protein phosphatase; Belongs to the PP2C family. (308 aa)
PDK2Protein-serine/threonine kinase. (407 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
DDIT4DNA damage inducible transcript 4. (285 aa)
APPAmyloid beta precursor protein. (770 aa)
PPARAPeroxisome proliferator activated receptor alpha. (470 aa)
SIRT4NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (466 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (843 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
PROX1Prospero homeobox 1. (738 aa)
NCOR1Nuclear receptor corepressor 1. (2435 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1276 aa)
ELOVL5Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (299 aa)
GIPGastric inhibitory polypeptide. (143 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1156 aa)
SIRT1Sirtuin 1. (734 aa)
SCAPSREBF chaperone. (1279 aa)
CLYBLCitrate lyase beta like. (341 aa)
PANK2Pantothenate kinase 2. (447 aa)
IRS2Insulin receptor substrate 2. (1325 aa)
DYRK2Dual specificity tyrosine phosphorylation regulated kinase 2. (599 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1016 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (460 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
APOEApolipoprotein E. (349 aa)
SPHK2Sphingosine kinase 2. (661 aa)
GFI1Growth factor independent 1 transcriptional repressor. (436 aa)
NCOA2Nuclear receptor coactivator. (1465 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
FBP1Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa)
PLIN5Perilipin; Belongs to the perilipin family. (456 aa)
SLC7A7Solute carrier family 7 member 7. (543 aa)
FGFR4Fibroblast growth factor receptor. (800 aa)
MIDNMidnolin. (496 aa)
FMO3Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (299 aa)
RESTRE1 silencing transcription factor. (1004 aa)
PDK1Protein-serine/threonine kinase. (438 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
WDTC1WD and tetratricopeptide repeats 1. (736 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
TTC39BTetratricopeptide repeat domain 39B. (681 aa)
DUSP12Dual specificity phosphatase 12. (345 aa)
LEPRLeptin receptor. (1165 aa)
INSIG2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (266 aa)
A0A4W2DH90Uncharacterized protein. (209 aa)
TWIST1Twist family bHLH transcription factor 1. (201 aa)
A0A4W2DHM0Uncharacterized protein. (56 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (542 aa)
DNM1LDynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (749 aa)
SIRT6Sirtuin 6. (391 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (567 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (659 aa)
BCKDKProtein-serine/threonine kinase. (335 aa)
A0A4W2DM58P-type domain-containing protein. (197 aa)
CLCN2Chloride channel protein. (911 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1103 aa)
A0A4W2BLA5CCDC144C domain-containing protein. (336 aa)
SEC14L5SEC14 like lipid binding 5. (722 aa)
A0A4W2BND6IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (100 aa)
GIT1GIT ArfGAP 1. (770 aa)
MLXIPLMLX interacting protein like. (856 aa)
CLN3Battenin. (460 aa)
JMJD8Jumonji domain containing 8. (269 aa)
A0A4W2BQI8Uncharacterized protein. (426 aa)
MID1IP1MID1 interacting protein 1. (182 aa)
FOXO1Forkhead box O1. (604 aa)
SIRT5NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinyl [...] (310 aa)
A0A4W2BS45Uncharacterized protein. (111 aa)
BMP6Bone morphogenetic protein 6. (525 aa)
DDB1Damage specific DNA binding protein 1. (1506 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (416 aa)
SLC2A6Solute carrier family 2 member 6; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (507 aa)
COX11Cytochrome c oxidase copper chaperone COX11. (281 aa)
PDZD3PDZ domain containing 3. (505 aa)
A0A4W2BWV5ANK_REP_REGION domain-containing protein. (353 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (613 aa)
SLC7A11Solute carrier family 7 member 11. (503 aa)
APOA5Apolipoprotein A5. (368 aa)
MST1Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (725 aa)
TYSND1Trypsin domain containing 1. (568 aa)
IGFBP4Insulin like growth factor binding protein 4. (290 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
EP300E1A binding protein p300. (2411 aa)
ARV1ARV1 homolog, fatty acid homeostasis modulator. (282 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1036 aa)
A0A4W2C1F6Uncharacterized protein. (278 aa)
PLA2G3Phospholipase A2 group III. (508 aa)
SEC14L4SEC14 like lipid binding 4. (406 aa)
GNMTGlycine N-methyltransferase. (312 aa)
GUCA1BGuanylate cyclase activator 1B. (204 aa)
A0A4W2C5I5Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (104 aa)
A0A4W2C692Uncharacterized protein. (396 aa)
FOXK1Forkhead box K1. (706 aa)
LPGAT1Lysophosphatidylglycerol acyltransferase 1. (370 aa)
NOS1Nitric oxide synthase 1. (1468 aa)
LCMT1Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (332 aa)
BADBCL2 associated agonist of cell death. (168 aa)
A0A4W2C9G4Uncharacterized protein. (232 aa)
LONP2Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (852 aa)
NLNNeurolysin. (681 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (901 aa)
SLC4A1Anion exchange protein. (1059 aa)
APOC3Apolipoprotein C3. (99 aa)
APOA4Apolipoprotein A4. (380 aa)
A0A4W2CD20ANK_REP_REGION domain-containing protein. (274 aa)
PMAIP1Phorbol-12-myristate-13-acetate-induced protein 1. (54 aa)
BEND3BEN domain containing 3. (1005 aa)
P2RY6Pyrimidinergic receptor P2Y6. (328 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (422 aa)
RANBP2RAN binding protein 2. (3143 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
AKT2AKT serine/threonine kinase 2. (603 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (211 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (701 aa)
INMTUncharacterized protein. (293 aa)
A0A4W2CRW3Annexin. (346 aa)
SERPINA12Serpin family A member 12; Belongs to the serpin family. (430 aa)
CBFA2T3CBFA2/RUNX1 partner transcriptional co-repressor 3. (631 aa)
PTHParathyroid hormone. (147 aa)
LPCAT3Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (485 aa)
FABP5Fatty acid binding protein 5; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa)
WDR5WD repeat domain 5. (334 aa)
ACACBAcetyl-CoA carboxylase beta. (2455 aa)
A0A4W2CP79Annexin. (335 aa)
GEMIN6Uncharacterized protein. (588 aa)
ENO1Enolase 1. (500 aa)
RORARAR related orphan receptor A. (527 aa)
FAM3CFamily with sequence similarity 3 member C. (227 aa)
SOX9SRY-box transcription factor 9. (524 aa)
INSRTyrosine-protein kinase receptor. (1382 aa)
SLC35B4Solute carrier family 35 member B4. (331 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (328 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (218 aa)
RD3Retinal degeneration 3, GUCY2D regulator. (195 aa)
CRY1Cryptochrome circadian regulator 1. (587 aa)
FMO1Flavin-containing monooxygenase. (612 aa)
NFKB1Nuclear factor kappa B subunit 1. (974 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (270 aa)
IGF1Insulin like growth factor 1. (188 aa)
CYP7A1Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (500 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (499 aa)
ADIPOR1Adiponectin receptor 1. (375 aa)
IGFBP3Insulin like growth factor binding protein 3. (291 aa)
A0A4W2HWU9Protein-serine/threonine kinase. (101 aa)
FOXK2Forkhead box K2. (658 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (565 aa)
ATCAYATCAY kinesin light chain interacting caytaxin. (397 aa)
PDK4Protein-serine/threonine kinase. (407 aa)
ATP5IF1ATP synthase inhibitory factor subunit 1. (109 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (842 aa)
PGPPhosphoglycolate phosphatase. (398 aa)
STARD4StAR related lipid transfer domain containing 4. (260 aa)
PIBF1Progesterone immunomodulatory binding factor 1. (757 aa)
GUCA1AUncharacterized protein. (205 aa)
MLYCDMalonyl-CoA decarboxylase. (499 aa)
LOC113893369CCDC144C domain-containing protein. (309 aa)
DKKL1Dickkopf like acrosomal protein 1. (277 aa)
ABCG4ATP binding cassette subfamily G member 4. (646 aa)
ZNF692Zinc finger protein 692. (598 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
NUPR1Nuclear protein 1, transcriptional regulator. (82 aa)
HTR2A5-hydroxytryptamine receptor 2A. (470 aa)
GCGGlucagon. (180 aa)
AK4-2Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. (223 aa)
PRMT3Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (527 aa)
EPM2AIP1EPM2A interacting protein 1. (608 aa)
APOC2Uncharacterized protein. (241 aa)
CD74CD74 molecule. (268 aa)
SNCAAlpha-synuclein; Belongs to the synuclein family. (140 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (447 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (486 aa)
GCKPhosphotransferase. (466 aa)
PID1Phosphotyrosine interaction domain containing 1. (217 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
C1QTNF12C1q and TNF related 12. (299 aa)
ZBTB20Zinc finger and BTB domain containing 20. (751 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
AKT1Non-specific serine/threonine protein kinase. (747 aa)
FLCNUDENN FLCN/SMCR8-type domain-containing protein. (579 aa)
SLC45A3Solute carrier family 45 member 3. (550 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa)
PRLUncharacterized protein. (230 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (244 aa)
DNAJC30DnaJ heat shock protein family (Hsp40) member C30. (226 aa)
NKX1-1NK1 homeobox 1. (398 aa)
KAT2BLysine acetyltransferase 2B. (990 aa)
A0A4W2F478Uncharacterized protein. (106 aa)
LDLRLow density lipoprotein receptor. (845 aa)
CYP27C1Cytochrome P450 family 27 subfamily C member 1; Belongs to the cytochrome P450 family. (537 aa)
SIK1Uncharacterized protein. (778 aa)
ACMSD2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (378 aa)
A0A4W2F1T9Dimethylaniline monooxygenase [N-oxide-forming]. (515 aa)
ETFBKMTElectron transfer flavoprotein subunit beta lysine methyltransferase. (266 aa)
C1QTNF6C1q and TNF related 6. (269 aa)
NR3C1Nuclear receptor subfamily 3 group C member 1. (782 aa)
TTC39ATetratricopeptide repeat domain 39A. (722 aa)
PPARGC1APPARG coactivator 1 alpha. (796 aa)
A0A4W2EWY4Uncharacterized protein. (214 aa)
GUCA2BGuanylate cyclase activator 2B. (113 aa)
SLC4A4Anion exchange protein. (1190 aa)
A0A4W2EW96Uncharacterized protein. (187 aa)
ABCB11ATP binding cassette subfamily B member 11. (1323 aa)
MFSD2AMajor facilitator superfamily domain containing 2A. (537 aa)
ERFEErythroferrone. (340 aa)
A0A4W2EVH5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1130 aa)
A0A4W2EUX9Uncharacterized protein. (178 aa)
EPHX2Epoxide hydrolase 2. (584 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1008 aa)
FMO5Flavin-containing monooxygenase. (644 aa)
PRXL2CPeroxiredoxin like 2C. (228 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (478 aa)
A0A4W2EQN1Phorbol-ester/DAG-type domain-containing protein. (322 aa)
PLEKPleckstrin. (348 aa)
GPD1Glycerol-3-phosphate dehydrogenase [NAD(+)]. (455 aa)
EIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa)
SLC27A4Solute carrier family 27 member 4. (643 aa)
H6PDHexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. (804 aa)
PARK7Parkinsonism associated deglycase. (190 aa)
A0A4W2EJS8ANK_REP_REGION domain-containing protein. (1397 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (266 aa)
ABCD2ATP binding cassette subfamily D member 2. (741 aa)
TRIB3Tribbles pseudokinase 3. (403 aa)
FMO4Dimethylaniline monooxygenase [N-oxide-forming]. (550 aa)
SIRT7Sirtuin 7. (420 aa)
ACADVLAcyl-CoA dehydrogenase very long chain. (677 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
NCS1Neuronal calcium sensor 1. (370 aa)
SEC14L3SEC14 like lipid binding 3. (400 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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