35 items (Bos indicus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	KAT2A	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
	USP27X	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (512 aa)
	SUPT3H	SPT3 homolog, SAGA and STAGA complex component. (438 aa)
	TAF5L	Uncharacterized protein. (591 aa)
	TAF6	TATA-box binding protein associated factor 6. (740 aa)
	SUPT20H	SPT20 homolog, SAGA complex component. (816 aa)
	TAF9	TATA-box binding protein associated factor 9. (264 aa)
	MAP3K7	Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
	A0A4W2CJR6	TFIID_20kDa domain-containing protein. (152 aa)
	TAF12	TFIID_20kDa domain-containing protein. (161 aa)
	SUPT7L	SPT7 like, STAGA complex gamma subunit. (412 aa)
	YEATS2	YEATS domain containing 2. (1412 aa)
	WDR5	WD repeat domain 5. (334 aa)
	MBIP	MAP3K12 binding inhibitory protein 1. (343 aa)
	SGF29	SAGA complex associated factor 29. (293 aa)
	ATXN7L3	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] (354 aa)
	POLE4	DNA polymerase epsilon 4, accessory subunit. (120 aa)
	TAF10	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
	KAT14	Lysine acetyltransferase 14. (781 aa)
	DR1	Down-regulator of transcription 1. (176 aa)
	TADA2B	Transcriptional adapter. (427 aa)
	A0A4W2EWB9	WD_REPEATS_REGION domain-containing protein. (571 aa)
	ZZZ3	Uncharacterized protein. (903 aa)
	KAT2B	Lysine acetyltransferase 2B. (990 aa)
	POLE3	DNA polymerase epsilon 3, accessory subunit. (147 aa)
	USP22	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (480 aa)
	TAF5	TATA-box binding protein associated factor 5. (800 aa)
	TAF2	TATA-box binding protein associated factor 2. (1251 aa)
	TADA3	Transcriptional adaptor 3. (432 aa)
	TAF6L	TATA-box binding protein associated factor 6 like. (665 aa)
	TRRAP	Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3874 aa)
	ENY2	Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (101 aa)
	TADA2A	Transcriptional adapter. (443 aa)
	TAF4	TATA-box binding protein associated factor 4. (1061 aa)
	TADA1	Transcriptional adaptor 1. (335 aa)

Your Current Organism:

Bos indicus

NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A4W2CJR6	A0A4W2EWB9	A0A4W2CJR6	A0A4W2EWB9	TFIID_20kDa domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.864
A0A4W2CJR6	ATXN7L3	A0A4W2CJR6	A0A4W2E953	TFIID_20kDa domain-containing protein.	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	0.868
A0A4W2CJR6	ENY2	A0A4W2CJR6	A0A4W2HWZ8	TFIID_20kDa domain-containing protein.	Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...]	0.875
A0A4W2CJR6	KAT2A	A0A4W2CJR6	A0A4W2E363	TFIID_20kDa domain-containing protein.	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	0.795
A0A4W2CJR6	KAT2B	A0A4W2CJR6	A0A4W2F492	TFIID_20kDa domain-containing protein.	Lysine acetyltransferase 2B.	0.795
A0A4W2CJR6	SGF29	A0A4W2CJR6	A0A4W2E7S8	TFIID_20kDa domain-containing protein.	SAGA complex associated factor 29.	0.918
A0A4W2CJR6	SUPT20H	A0A4W2CJR6	A0A4W2C4W6	TFIID_20kDa domain-containing protein.	SPT20 homolog, SAGA complex component.	0.893
A0A4W2CJR6	SUPT3H	A0A4W2CJR6	A0A4W2BZV3	TFIID_20kDa domain-containing protein.	SPT3 homolog, SAGA and STAGA complex component.	0.916
A0A4W2CJR6	SUPT7L	A0A4W2CJR6	A0A4W2CXP4	TFIID_20kDa domain-containing protein.	SPT7 like, STAGA complex gamma subunit.	0.902
A0A4W2CJR6	TADA1	A0A4W2CJR6	A0A4W2I858	TFIID_20kDa domain-containing protein.	Transcriptional adaptor 1.	0.831
A0A4W2CJR6	TADA2A	A0A4W2CJR6	A0A4W2I3F0	TFIID_20kDa domain-containing protein.	Transcriptional adapter.	0.872
A0A4W2CJR6	TADA2B	A0A4W2CJR6	A0A4W2ERU9	TFIID_20kDa domain-containing protein.	Transcriptional adapter.	0.829
A0A4W2CJR6	TADA3	A0A4W2CJR6	A0A4W2H485	TFIID_20kDa domain-containing protein.	Transcriptional adaptor 3.	0.898
A0A4W2CJR6	TAF10	A0A4W2CJR6	A0A4W2EKG6	TFIID_20kDa domain-containing protein.	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.	0.989
A0A4W2CJR6	TAF2	A0A4W2CJR6	A0A4W2H1X1	TFIID_20kDa domain-containing protein.	TATA-box binding protein associated factor 2.	0.986
A0A4W2CJR6	TAF4	A0A4W2CJR6	A0A4W2I5M9	TFIID_20kDa domain-containing protein.	TATA-box binding protein associated factor 4.	0.991
A0A4W2CJR6	TAF5	A0A4W2CJR6	A0A4W2FW37	TFIID_20kDa domain-containing protein.	TATA-box binding protein associated factor 5.	0.988
A0A4W2CJR6	TAF5L	A0A4W2CJR6	A0A4W2C0P4	TFIID_20kDa domain-containing protein.	Uncharacterized protein.	0.882
A0A4W2CJR6	TAF6	A0A4W2CJR6	A0A4W2C2B0	TFIID_20kDa domain-containing protein.	TATA-box binding protein associated factor 6.	0.989
A0A4W2CJR6	TAF6L	A0A4W2CJR6	A0A4W2HMP3	TFIID_20kDa domain-containing protein.	TATA-box binding protein associated factor 6 like.	0.952

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