STRINGSTRING
AQR AQR SF3B6 SF3B6 RALY RALY PRPF6 PRPF6 A0A4W2EGB2 A0A4W2EGB2 A0A4W2EFI8 A0A4W2EFI8 A0A4W2EF32 A0A4W2EF32 PPIL1 PPIL1 CDC5L CDC5L A0A4W2ECI1 A0A4W2ECI1 SF3B3 SF3B3 A0A4W2E935 A0A4W2E935 ESS2 ESS2 PNN PNN SNRPD1 SNRPD1 A0A4W2BMG6 A0A4W2BMG6 BUD31 BUD31 A0A4W2BPQ2 A0A4W2BPQ2 LSM3 LSM3 A0A4W2BRU2 A0A4W2BRU2 SART1 SART1 LSM2 LSM2 TFIP11 TFIP11 WDR25 WDR25 A0A4W2C7G8 A0A4W2C7G8 SNRPD1-2 SNRPD1-2 EFTUD2 EFTUD2 MTREX MTREX DHX8 DHX8 FRG1 FRG1 PPIL3 PPIL3 SYNCRIP SYNCRIP SNRPD1-3 SNRPD1-3 PABPC1 PABPC1 PPIL2 PPIL2 PPWD1 PPWD1 ZCCHC8 ZCCHC8 SNRPB SNRPB DHX38 DHX38 HNRNPU HNRNPU SNRPG SNRPG A0A4W2CYM3 A0A4W2CYM3 HNRNPA1 HNRNPA1 DDX23 DDX23 CACTIN CACTIN SF3A2 SF3A2 EIF4A2 EIF4A2 PPIE PPIE A0A4W2DFX9 A0A4W2DFX9 A0A4W2DIR9 A0A4W2DIR9 SRRM2 SRRM2 PRPF19 PRPF19 A0A4W2DML3 A0A4W2DML3 DDX41 DDX41 A0A4W2DT27 A0A4W2DT27 ISY1 ISY1 EIF4A3 EIF4A3 CWC15 CWC15 RBM22 RBM22 DDX5 DDX5 CDC40 CDC40 SNRPB2 SNRPB2 U2AF1 U2AF1 CWC27 CWC27 PLRG1 PLRG1 GPATCH1 GPATCH1 PRPF4B PRPF4B A0A4W2IAG7 A0A4W2IAG7 SF3B2 SF3B2 SNRPD3 SNRPD3 XAB2 XAB2 SNRNP40 SNRNP40 CRNKL1 CRNKL1 SF3A3 SF3A3 SRSF1 SRSF1 A0A4W2H082 A0A4W2H082 SNRPN SNRPN SNRPD2 SNRPD2 BCAS2 BCAS2 C19orf54 C19orf54 A0A4W2FX29 A0A4W2FX29 SNRPA1 SNRPA1 PRPF8 PRPF8 SF3B1 SF3B1 SF3A1 SF3A1 A0A4W2F479 A0A4W2F479 SLU7 SLU7 WDR83 WDR83 A0A4W2F0M1 A0A4W2F0M1 MAGOH MAGOH MAGOHB MAGOHB A0A4W2EWI5 A0A4W2EWI5 SYF2 SYF2 HNRNPH1 HNRNPH1 HNRNPR HNRNPR SRRM1 SRRM1 RBM44 RBM44 HNRNPA3 HNRNPA3 CWC22 CWC22 HNRNPK HNRNPK LSM7 LSM7 SNW1 SNW1 DHX35 DHX35 SNRNP200 SNRNP200 A0A4W2EMR3 A0A4W2EMR3
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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AQRRNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1484 aa)
SF3B6Splicing factor 3b subunit 6. (125 aa)
RALYRALY heterogeneous nuclear ribonucleoprotein. (331 aa)
PRPF6Pre-mRNA processing factor 6. (1044 aa)
A0A4W2EGB2Uncharacterized protein. (364 aa)
A0A4W2EFI8RRM domain-containing protein. (396 aa)
A0A4W2EF32Uncharacterized protein. (300 aa)
PPIL1Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa)
CDC5LCell division cycle 5 like. (802 aa)
A0A4W2ECI1Uncharacterized protein. (138 aa)
SF3B3Splicing factor 3b subunit 3. (1217 aa)
A0A4W2E935Sm domain-containing protein. (81 aa)
ESS2Ess-2 splicing factor homolog. (478 aa)
PNNPinin, desmosome associated protein. (721 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (119 aa)
A0A4W2BMG6RRM domain-containing protein. (387 aa)
BUD31BUD31 homolog. (144 aa)
A0A4W2BPQ2RRM domain-containing protein. (188 aa)
LSM3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
A0A4W2BRU2Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (68 aa)
SART1Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (802 aa)
LSM2U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
TFIP11Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (837 aa)
WDR25WD repeat domain 25. (567 aa)
A0A4W2C7G8Uncharacterized protein. (112 aa)
SNRPD1-2Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (119 aa)
EFTUD2Elongation factor Tu GTP binding domain containing 2. (1004 aa)
MTREXMtr4 exosome RNA helicase. (1040 aa)
DHX8DEAH-box helicase 8. (1220 aa)
FRG1Uncharacterized protein. (250 aa)
PPIL3Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (161 aa)
SYNCRIPSynaptotagmin binding cytoplasmic RNA interacting protein. (562 aa)
SNRPD1-3Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (120 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (636 aa)
PPIL2Peptidylprolyl isomerase like 2. (522 aa)
PPWD1Peptidylprolyl isomerase domain and WD repeat containing 1. (644 aa)
ZCCHC8Zinc finger CCHC-type containing 8. (707 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein. (231 aa)
DHX38DEAH-box helicase 38. (1227 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (806 aa)
SNRPGSmall nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
A0A4W2CYM3Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (77 aa)
HNRNPA1Heterogeneous nuclear ribonucleoprotein A1. (373 aa)
DDX23DEAD-box helicase 23. (909 aa)
CACTINCactin, spliceosome C complex subunit. (756 aa)
SF3A2Splicing factor 3a subunit 2. (477 aa)
EIF4A2Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family. (407 aa)
PPIEPeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (301 aa)
A0A4W2DFX9RRM domain-containing protein. (115 aa)
A0A4W2DIR9LRRcap domain-containing protein. (360 aa)
SRRM2Serine/arginine repetitive matrix 2. (2741 aa)
PRPF19Pre-mRNA processing factor 19. (504 aa)
A0A4W2DML3Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (64 aa)
DDX41DEAD-box helicase 41. (673 aa)
A0A4W2DT27RRM domain-containing protein. (92 aa)
ISY1Uncharacterized protein. (284 aa)
EIF4A3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (411 aa)
CWC15CWC15 spliceosome associated protein homolog. (238 aa)
RBM22RNA binding motif protein 22. (420 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa)
CDC40Cell division cycle 40. (611 aa)
SNRPB2Uncharacterized protein. (225 aa)
U2AF1Uncharacterized protein. (237 aa)
CWC27CWC27 spliceosome associated cyclophilin. (473 aa)
PLRG1Pleiotropic regulator 1. (513 aa)
GPATCH1G-patch domain containing 1. (931 aa)
PRPF4BPre-mRNA processing factor 4B. (1069 aa)
A0A4W2IAG7Sm domain-containing protein. (65 aa)
SF3B2Splicing factor 3b subunit 2. (895 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
XAB2XPA binding protein 2. (855 aa)
SNRNP40Small nuclear ribonucleoprotein U5 subunit 40. (358 aa)
CRNKL1Crooked neck pre-mRNA splicing factor 1. (693 aa)
SF3A3Splicing factor 3a subunit 3. (501 aa)
SRSF1Uncharacterized protein. (248 aa)
A0A4W2H082Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (68 aa)
SNRPNSmall nuclear ribonucleoprotein-associated protein. (240 aa)
SNRPD2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (118 aa)
BCAS2BCAS2 pre-mRNA processing factor. (225 aa)
C19orf54Chromosome 19 open reading frame 54. (348 aa)
A0A4W2FX29Helicase C-terminal domain-containing protein. (177 aa)
SNRPA1LRRcap domain-containing protein. (255 aa)
PRPF8Pre-mRNA processing factor 8. (2335 aa)
SF3B1Splicing factor 3b subunit 1. (1304 aa)
SF3A1Splicing factor 3a subunit 1. (793 aa)
A0A4W2F479Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa)
SLU7SLU7 homolog, splicing factor. (586 aa)
WDR83WD repeat domain 83. (315 aa)
A0A4W2F0M1Uncharacterized protein. (320 aa)
MAGOHMago homolog, exon junction complex subunit. (146 aa)
MAGOHBMago homolog B, exon junction complex subunit. (148 aa)
A0A4W2EWI5Uncharacterized protein. (369 aa)
SYF2SYF2 pre-mRNA splicing factor. (245 aa)
HNRNPH1Heterogeneous nuclear ribonucleoprotein H1. (482 aa)
HNRNPRHeterogeneous nuclear ribonucleoprotein R. (633 aa)
SRRM1Serine and arginine repetitive matrix 1. (915 aa)
RBM44RNA binding motif protein 44. (1051 aa)
HNRNPA3Heterogeneous nuclear ribonucleoprotein A3. (380 aa)
CWC22CWC22 spliceosome associated protein homolog. (900 aa)
HNRNPKUncharacterized protein. (464 aa)
LSM7LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (103 aa)
SNW1SNW domain containing 1. (536 aa)
DHX35DEAH-box helicase 35. (703 aa)
SNRNP200Small nuclear ribonucleoprotein U5 subunit 200. (2136 aa)
A0A4W2EMR3RRM domain-containing protein. (115 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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