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LAMTOR3 LAMTOR3 PDGFC PDGFC TNF TNF IPO5 IPO5 COL4A1 COL4A1 RRAGD RRAGD LOC113897311 LOC113897311 CPEB3 CPEB3 PDGFD PDGFD CPEB4 CPEB4 RPTOR RPTOR LAMTOR2 LAMTOR2 A0A4W2BKU6 A0A4W2BKU6 SESN3 SESN3 SOCS1 SOCS1 AMIGO3 AMIGO3 RRAGB RRAGB CASTOR1 CASTOR1 A0A4W2C839 A0A4W2C839 LARS LARS RRAGC RRAGC COL5A2 COL5A2 COL3A1 COL3A1 MMP2 MMP2 SLC38A9 SLC38A9 UBR2 UBR2 MTOR MTOR SESN2 SESN2 COL16A1 COL16A1 CAPN2 CAPN2 ZEB1 ZEB1 AMIGO1 AMIGO1 LAMTOR5 LAMTOR5 A0A4W2D7Y4 A0A4W2D7Y4 SH3BP4 SH3BP4 A0A4W2D9S8 A0A4W2D9S8 UBR1 UBR1 GLRA1 GLRA1 KLHL22 KLHL22 A0A4W2DPV9 A0A4W2DPV9 LAMTOR4 LAMTOR4 DNMT3A DNMT3A A0A4W2DGF3 A0A4W2DGF3 A0A4W2DI91 A0A4W2DI91 DNMT1 DNMT1 SESN1 SESN1 COL1A1 COL1A1 CASTOR2 CASTOR2 PDGFRA PDGFRA NEURL1 NEURL1 COL1A2 COL1A2 COL6A1 COL6A1 NTRK2 NTRK2 CEBPB CEBPB LAMTOR1 LAMTOR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LAMTOR3Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa)
PDGFCPlatelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (397 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (333 aa)
IPO5Importin 5. (1097 aa)
COL4A1Collagen type IV alpha 1 chain. (1669 aa)
RRAGDRas related GTP binding D. (413 aa)
LOC113897311Uncharacterized protein. (313 aa)
CPEB3Cytoplasmic polyadenylation element binding protein 3. (714 aa)
PDGFDPlatelet derived growth factor D; Belongs to the PDGF/VEGF growth factor family. (558 aa)
CPEB4Cytoplasmic polyadenylation element binding protein 4. (729 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1335 aa)
LAMTOR2Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (125 aa)
A0A4W2BKU6Uncharacterized protein. (91 aa)
SESN3Sestrin 3. (492 aa)
SOCS1Suppressor of cytokine signaling 1. (224 aa)
AMIGO3Adhesion molecule with Ig like domain 3. (519 aa)
RRAGBRas related GTP binding B. (374 aa)
CASTOR1Cytosolic arginine sensor for mTORC1 subunit 1. (329 aa)
A0A4W2C839BZIP domain-containing protein. (376 aa)
LARSLeucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1176 aa)
RRAGCRas related GTP binding C. (399 aa)
COL5A2Collagen type V alpha 2 chain. (1499 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
MMP2Matrix metallopeptidase 2. (661 aa)
SLC38A9Solute carrier family 38 member 9. (561 aa)
UBR2E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1756 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
SESN2Sestrin 2. (482 aa)
COL16A1Collagen type XVI alpha 1 chain. (1625 aa)
CAPN2Calpain 2; Belongs to the peptidase C2 family. (700 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1177 aa)
AMIGO1Adhesion molecule with Ig like domain 1. (493 aa)
LAMTOR5Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (91 aa)
A0A4W2D7Y4Uncharacterized protein. (344 aa)
SH3BP4SH3 domain binding protein 4. (963 aa)
A0A4W2D9S8Uncharacterized protein. (346 aa)
UBR1E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1753 aa)
GLRA1Glycine receptor alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (457 aa)
KLHL22Kelch like family member 22. (634 aa)
A0A4W2DPV9Uncharacterized protein. (91 aa)
LAMTOR4Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (104 aa)
DNMT3ADNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (957 aa)
A0A4W2DGF3Uncharacterized protein. (318 aa)
A0A4W2DI91Uncharacterized protein. (399 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1708 aa)
SESN1Sestrin 1. (551 aa)
COL1A1Collagen type I alpha 1 chain. (1584 aa)
CASTOR2Uncharacterized protein. (329 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1098 aa)
NEURL1Neuralized E3 ubiquitin protein ligase 1. (574 aa)
COL1A2Collagen type I alpha 2 chain. (1364 aa)
COL6A1Uncharacterized protein. (1027 aa)
NTRK2Tyrosine-protein kinase receptor. (837 aa)
CEBPBCCAAT/enhancer-binding protein. (348 aa)
LAMTOR1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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