STRINGSTRING
PKD2 PKD2 ITPR2 ITPR2 HCN2 HCN2 DMTN DMTN ZFP36L1 ZFP36L1 HCN1 HCN1 RAPGEF2 RAPGEF2 HCN4 HCN4 EZR EZR RAPGEF3 RAPGEF3 WNT10B WNT10B AQP9 AQP9 CFTR CFTR A0A4W2I4T1 A0A4W2I4T1 AQP1 AQP1 HCN3 HCN3 RAP1B RAP1B KCNQ1 KCNQ1 RAP1A RAP1A SLC26A6 SLC26A6 AKAP6 AKAP6 FDX1 FDX1 AQP8 AQP8 GPD1 GPD1 IGFBP5 IGFBP5 PDE2A PDE2A WT1 WT1 A0A4W2DVU2 A0A4W2DVU2 AKAP9 AKAP9 PIK3CG PIK3CG INPP5K INPP5K SLC26A3 SLC26A3 SLC5A5 SLC5A5 A0A4W2EX93 A0A4W2EX93
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PKD2Polycystin 2, transient receptor potential cation channel. (1071 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
HCN2Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (902 aa)
DMTNDematin actin binding protein. (467 aa)
ZFP36L1ZFP36 ring finger protein like 1. (323 aa)
HCN1Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (877 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1689 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1201 aa)
EZREzrin. (638 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (923 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (433 aa)
AQP9Aquaporin 9; Belongs to the MIP/aquaporin (TC 1.A.8) family. (295 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1481 aa)
A0A4W2I4T1Uncharacterized protein. (139 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
HCN3Hyperpolarization activated cyclic nucleotide gated potassium channel 3. (783 aa)
RAP1BUncharacterized protein. (184 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (670 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
SLC26A6Solute carrier family 26 member 6. (763 aa)
AKAP6A-kinase anchoring protein 6. (2319 aa)
FDX1Ferredoxin 1. (196 aa)
AQP8Aquaporin 8; Belongs to the MIP/aquaporin (TC 1.A.8) family. (330 aa)
GPD1Glycerol-3-phosphate dehydrogenase [NAD(+)]. (455 aa)
IGFBP5Insulin like growth factor binding protein 5. (271 aa)
PDE2APhosphodiesterase. (943 aa)
WT1WT1 transcription factor. (518 aa)
A0A4W2DVU2PAS domain-containing protein. (743 aa)
AKAP9A-kinase anchoring protein 9. (3907 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1171 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (449 aa)
SLC26A3Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (760 aa)
SLC5A5Solute carrier family 5 member 5; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (642 aa)
A0A4W2EX93BHLH domain-containing protein. (119 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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