Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| A0A4W2GYG4 | HRAS | A0A4W2GYG4 | A0A4W2H9P0 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | HRas proto-oncogene, GTPase. | 0.889 |
| A0A4W2GYG4 | PRKCD | A0A4W2GYG4 | A0A4W2DQ88 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.844 |
| ABL1 | CDKN1A | A0A4W2CTP7 | A0A4W2EED6 | Tyrosine-protein kinase. | Cyclin dependent kinase inhibitor 1A. | 0.411 |
| ABL1 | HRAS | A0A4W2CTP7 | A0A4W2H9P0 | Tyrosine-protein kinase. | HRas proto-oncogene, GTPase. | 0.451 |
| ABL1 | TP53 | A0A4W2CTP7 | A0A4W2I2P0 | Tyrosine-protein kinase. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.532 |
| BRCA2 | TP53 | A0A4W2BPN3 | A0A4W2I2P0 | BRCA2 DNA repair associated. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.868 |
| BRCA2 | TP63 | A0A4W2BPN3 | A0A4W2GV23 | BRCA2 DNA repair associated. | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. | 0.436 |
| BRCA2 | WRN | A0A4W2BPN3 | A0A4W2BW89 | BRCA2 DNA repair associated. | WRN RecQ like helicase. | 0.920 |
| CDKN1A | ABL1 | A0A4W2EED6 | A0A4W2CTP7 | Cyclin dependent kinase inhibitor 1A. | Tyrosine-protein kinase. | 0.411 |
| CDKN1A | SIRT1 | A0A4W2EED6 | A0A4W2DSK9 | Cyclin dependent kinase inhibitor 1A. | Sirtuin 1. | 0.504 |
| CDKN1A | TP53 | A0A4W2EED6 | A0A4W2I2P0 | Cyclin dependent kinase inhibitor 1A. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.995 |
| CDKN1A | TP63 | A0A4W2EED6 | A0A4W2GV23 | Cyclin dependent kinase inhibitor 1A. | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. | 0.466 |
| HMGA2 | TP53 | A0A4W2EH15 | A0A4W2I2P0 | Uncharacterized protein. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.419 |
| HRAS | A0A4W2GYG4 | A0A4W2H9P0 | A0A4W2GYG4 | HRas proto-oncogene, GTPase. | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | 0.889 |
| HRAS | ABL1 | A0A4W2H9P0 | A0A4W2CTP7 | HRas proto-oncogene, GTPase. | Tyrosine-protein kinase. | 0.451 |
| HRAS | MAP2K1 | A0A4W2H9P0 | A0A4W2D4M5 | HRas proto-oncogene, GTPase. | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | 0.889 |
| HRAS | PRKCD | A0A4W2H9P0 | A0A4W2DQ88 | HRas proto-oncogene, GTPase. | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. | 0.494 |
| HRAS | TP53 | A0A4W2H9P0 | A0A4W2I2P0 | HRas proto-oncogene, GTPase. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.598 |
| KAT6A | PML | A0A4W2BX17 | A0A4W2EAS9 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. | Promyelocytic leukemia. | 0.532 |
| KAT6A | SIRT1 | A0A4W2BX17 | A0A4W2DSK9 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. | Sirtuin 1. | 0.447 |
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