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SLC9A1 SLC9A1 ATP12A ATP12A CACNA1F CACNA1F SLC5A2 SLC5A2 SLC39A6 SLC39A6 SLC3A2 SLC3A2 SLC7A11 SLC7A11 A0A4W2BYF2 A0A4W2BYF2 SLC7A2 SLC7A2 KCNJ4 KCNJ4 SLC7A1 SLC7A1 CACNA1C CACNA1C SCNN1A SCNN1A SLC7A5 SLC7A5 KCNJ11 KCNJ11 SLC12A4 SLC12A4 SLC15A4 SLC15A4 A0A4W2CBM0 A0A4W2CBM0 LOC113876033 LOC113876033 GFAP GFAP TRPV1 TRPV1 FOLR2 FOLR2 A0A4W2CGJ1 A0A4W2CGJ1 LOC113876049 LOC113876049 A0A4W2CGS9 A0A4W2CGS9 SLC9A3 SLC9A3 KCNJ14 KCNJ14 A0A4W2CJW7 A0A4W2CJW7 KCNJ16 KCNJ16 SLC27A5 SLC27A5 SLC39A12 SLC39A12 SLC8A1 SLC8A1 SLC1A2 SLC1A2 TRPV4 TRPV4 ATP4B ATP4B SLC24A4 SLC24A4 SLC2A10 SLC2A10 TRPV3 TRPV3 SLC1A1 SLC1A1 ATP1B1 ATP1B1 FAM155A FAM155A A0A4W2D0V9 A0A4W2D0V9 KCNJ2 KCNJ2 SLC22A2 SLC22A2 SLC7A8 SLC7A8 LRRC8C LRRC8C HCN4 HCN4 TRPV5 TRPV5 STEAP2 STEAP2 KCNH2 KCNH2 PAWR PAWR HCN2 HCN2 SLC5A6 SLC5A6 TRPM2 TRPM2 SLC27A1 SLC27A1 SLC9A9 SLC9A9 KCNE2 KCNE2 KCNJ10 KCNJ10 SLC19A1 SLC19A1 SCN11A SCN11A KCNJ15 KCNJ15 CACNA1D CACNA1D SLC6A20 SLC6A20 LRP2 LRP2 CACNA1G CACNA1G SCNN1B SCNN1B CACNA1S CACNA1S SLC1A4 SLC1A4 SLC5A1 SLC5A1 SLC39A4 SLC39A4 TRPV2 TRPV2 FOLR1 FOLR1 KCNK9 KCNK9 CACNA1E CACNA1E SLC8A2 SLC8A2 SLC6A6 SLC6A6 SLC12A1 SLC12A1 ATP4A ATP4A LOC113876050 LOC113876050 A0A4W2EBN8 A0A4W2EBN8 A0A4W2EBZ3 A0A4W2EBZ3 SLC9A4 SLC9A4 A0A4W2EED2 A0A4W2EED2 SLC1A5 SLC1A5 SLC2A5 SLC2A5 SLC15A1 SLC15A1 SLC12A3 SLC12A3 A0A4W2EKS4 A0A4W2EKS4 SLC9A2 SLC9A2 SLC9C1 SLC9C1 SLC24A2 SLC24A2 SLC12A6 SLC12A6 SLC12A8 SLC12A8 PSEN1 PSEN1 SLC12A2 SLC12A2 SLC39A14 SLC39A14 SCN9A SCN9A SCN1A SCN1A SLC2A1 SLC2A1 KCNJ3 KCNJ3 KCNJ9 KCNJ9 ADGRV1 ADGRV1 SLC39A5 SLC39A5 SLC39A10 SLC39A10 ATP1B3 ATP1B3 SLC9A7 SLC9A7 TRPV6 TRPV6 LRRC8E LRRC8E HFE HFE SLC12A5 SLC12A5 SLC46A1 SLC46A1 ATP1A4 ATP1A4 ATP1A3 ATP1A3 ATP1A2 ATP1A2 A0A4W2GAB5 A0A4W2GAB5 LOC113876037 LOC113876037 SCNN1G SCNN1G ATP1A1 ATP1A1 CLN8 CLN8 SLC39A8 SLC39A8 SLC6A1 SLC6A1 KCNJ13 KCNJ13 KCNQ1 KCNQ1 SLC12A7 SLC12A7 TRPM4 TRPM4 KCNJ1 KCNJ1 KCNJ5 KCNJ5 SLC1A3 SLC1A3 SLC15A3 SLC15A3 KCNJ8 KCNJ8 KCNJ6 KCNJ6 SCN8A SCN8A LRRC8A LRRC8A LOC113876027 LOC113876027 SLC9A5 SLC9A5 A0A4W2I1Z3 A0A4W2I1Z3 ATP1B2 ATP1B2 SLC36A1 SLC36A1 GRM1 GRM1 SLC7A3 SLC7A3 ARL6IP5 ARL6IP5 SLC8A3 SLC8A3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (818 aa)
ATP12ASodium/potassium-transporting ATPase subunit alpha. (1017 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1929 aa)
SLC5A2Solute carrier family 5 member 2; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (673 aa)
SLC39A6Solute carrier family 39 member 6. (747 aa)
SLC3A2Solute carrier family 3 member 2. (572 aa)
SLC7A11Solute carrier family 7 member 11. (503 aa)
A0A4W2BYF2Uncharacterized protein. (968 aa)
SLC7A2Solute carrier family 7 member 2. (659 aa)
KCNJ4Potassium voltage-gated channel subfamily J member 4. (444 aa)
SLC7A1Solute carrier family 7 member 1. (629 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2194 aa)
SCNN1ASodium channel epithelial 1 alpha subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (682 aa)
SLC7A5Solute carrier family 7 member 5. (507 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (388 aa)
SLC12A4Solute carrier family 12 member 4. (1086 aa)
SLC15A4Solute carrier family 15 member 4. (566 aa)
A0A4W2CBM0Uncharacterized protein. (363 aa)
LOC113876033AA_permease_C domain-containing protein. (708 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (468 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (837 aa)
FOLR2Folate receptor beta. (253 aa)
A0A4W2CGJ1Uncharacterized protein. (378 aa)
LOC113876049Uncharacterized protein. (531 aa)
A0A4W2CGS9AA_permease_C domain-containing protein. (606 aa)
SLC9A3Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (835 aa)
KCNJ14Potassium voltage-gated channel subfamily J member 14. (434 aa)
A0A4W2CJW7AA_permease_C domain-containing protein. (645 aa)
KCNJ16Potassium voltage-gated channel subfamily J member 16. (420 aa)
SLC27A5Solute carrier family 27 member 5. (690 aa)
SLC39A12Solute carrier family 39 member 12. (754 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
SLC1A2Amino acid transporter. (595 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (803 aa)
ATP4BSodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
SLC24A4Solute carrier family 24 member 4; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (622 aa)
SLC2A10Solute carrier family 2 member 10; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (536 aa)
TRPV3Transient receptor potential cation channel subfamily V member 3; Belongs to the transient receptor (TC 1.A.4) family. (798 aa)
SLC1A1Amino acid transporter. (524 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
FAM155AFamily with sequence similarity 155 member A. (455 aa)
A0A4W2D0V9AA_permease_C domain-containing protein. (623 aa)
KCNJ2Potassium voltage-gated channel subfamily J member 2. (427 aa)
SLC22A2Solute carrier family 22 member 2. (549 aa)
SLC7A8Solute carrier family 7 member 8. (528 aa)
LRRC8CLeucine rich repeat containing 8 VRAC subunit C. (839 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1201 aa)
TRPV5Transient receptor potential cation channel subfamily V member 5; Belongs to the transient receptor (TC 1.A.4) family. (731 aa)
STEAP2STEAP2 metalloreductase. (490 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2. (1161 aa)
PAWRPro-apoptotic WT1 regulator. (344 aa)
HCN2Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (902 aa)
SLC5A6Solute carrier family 5 member 6; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (736 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1499 aa)
SLC27A1Solute carrier family 27 member 1. (676 aa)
SLC9A9Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (640 aa)
KCNE2Potassium voltage-gated channel subfamily E regulatory subunit 2. (123 aa)
KCNJ10Potassium voltage-gated channel subfamily J member 10. (379 aa)
SLC19A1Solute carrier family 19 member 1. (572 aa)
SCN11ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1782 aa)
KCNJ15Potassium voltage-gated channel subfamily J member 15. (375 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2183 aa)
SLC6A20Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (592 aa)
LRP2LDL receptor related protein 2. (4647 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2380 aa)
SCNN1BSodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (736 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1872 aa)
SLC1A4Solute carrier family 1 member 4. (546 aa)
SLC5A1Solute carrier family 5 member 1; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (664 aa)
SLC39A4Solute carrier family 39 member 4. (653 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (799 aa)
FOLR1Folate receptor alpha. (287 aa)
KCNK9Potassium two pore domain channel subfamily K member 9; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (503 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2447 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (922 aa)
SLC6A6Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (874 aa)
SLC12A1Solute carrier family 12 member 1. (1099 aa)
ATP4ASodium/potassium-transporting ATPase subunit alpha. (1034 aa)
LOC113876050AA_permease_C domain-containing protein. (626 aa)
A0A4W2EBN8AA_permease_C domain-containing protein. (621 aa)
A0A4W2EBZ3Uncharacterized protein. (246 aa)
SLC9A4Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (797 aa)
A0A4W2EED2Uncharacterized protein. (385 aa)
SLC1A5Amino acid transporter. (539 aa)
SLC2A5Solute carrier family 2 member 5; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (508 aa)
SLC15A1Solute carrier family 15 member 1. (707 aa)
SLC12A3Solute carrier family 12 member 3. (1030 aa)
A0A4W2EKS4Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (316 aa)
SLC9A2Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (809 aa)
SLC9C1Solute carrier family 9 member C1. (1145 aa)
SLC24A2Solute carrier family 24 member 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (664 aa)
SLC12A6Solute carrier family 12 member 6. (1150 aa)
SLC12A8Solute carrier family 12 member 8. (686 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (478 aa)
SLC12A2Solute carrier family 12 member 2. (1204 aa)
SLC39A14Solute carrier family 39 member 14. (531 aa)
SCN9ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1987 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2009 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (530 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (434 aa)
ADGRV1Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family. (6300 aa)
SLC39A5Solute carrier family 39 member 5. (542 aa)
SLC39A10Solute carrier family 39 member 10. (832 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa)
SLC9A7Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (731 aa)
TRPV6Transient receptor potential cation channel subfamily V member 6; Belongs to the transient receptor (TC 1.A.4) family. (761 aa)
LRRC8ELeucine rich repeat containing 8 VRAC subunit E. (796 aa)
HFEHomeostatic iron regulator; Belongs to the MHC class I family. (400 aa)
SLC12A5Solute carrier family 12 member 5. (1144 aa)
SLC46A1Solute carrier family 46 member 1. (459 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1030 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1048 aa)
A0A4W2GAB5Uncharacterized protein. (618 aa)
LOC113876037AA_permease_C domain-containing protein. (604 aa)
SCNN1GSodium channel epithelial 1 gamma subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (652 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1021 aa)
CLN8CLN8 transmembrane ER and ERGIC protein. (339 aa)
SLC39A8Solute carrier family 39 member 8. (461 aa)
SLC6A1Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (606 aa)
KCNJ13Potassium voltage-gated channel subfamily J member 13. (360 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (670 aa)
SLC12A7Solute carrier family 12 member 7. (1091 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1207 aa)
KCNJ1Potassium voltage-gated channel subfamily J member 1. (385 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (419 aa)
SLC1A3Amino acid transporter. (542 aa)
SLC15A3Solute carrier family 15 member 3. (581 aa)
KCNJ8Potassium voltage-gated channel subfamily J member 8. (424 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (423 aa)
SCN8ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1980 aa)
LRRC8ALeucine rich repeat containing 8 VRAC subunit A. (810 aa)
LOC113876027AA_permease_C domain-containing protein. (612 aa)
SLC9A5Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (900 aa)
A0A4W2I1Z3AA_permease_C domain-containing protein. (645 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
SLC36A1Solute carrier family 36 member 1. (476 aa)
GRM1Glutamate metabotropic receptor 1. (1192 aa)
SLC7A3Solute carrier family 7 member 3. (619 aa)
ARL6IP5PRA1 family protein. (188 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (928 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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