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LRRC4B LRRC4B GRIN2A GRIN2A GRM5 GRM5 GRIN3B GRIN3B DCC DCC CACNA1C CACNA1C LRFN5 LRFN5 CACNG5 CACNG5 LRFN2 LRFN2 ADAM22 ADAM22 CLSTN3 CLSTN3 RGS7BP RGS7BP LRRC4 LRRC4 LRFN1 LRFN1 PLPPR4 PLPPR4 DLG1 DLG1 LIN7A LIN7A SIGMAR1 SIGMAR1 SYNJ2BP SYNJ2BP CACNG2 CACNG2 SORCS3 SORCS3 GSG1L GSG1L PRRT1 PRRT1 PTPRO PTPRO SHISA9 SHISA9 LIN7C LIN7C GRIN2C GRIN2C DLG4 DLG4 LIN7B LIN7B SYNDIG1 SYNDIG1 ATP2B2 ATP2B2 ADCY1 ADCY1 CACNG4 CACNG4 GRIN2D GRIN2D RGS9 RGS9 KCNH1 KCNH1 NPTN NPTN SLITRK3 SLITRK3 ABHD17A ABHD17A CLSTN2 CLSTN2 GRID2 GRID2 DAGLA DAGLA GRIN2B GRIN2B ABHD17C ABHD17C LRRC4C LRRC4C LRFN4 LRFN4 CACNG8 CACNG8 CACNG3 CACNG3 NETO1 NETO1 ERBB4 ERBB4 MPP2 MPP2 CACNG7 CACNG7 GRIA1 GRIA1 GRM1 GRM1 GRID1 GRID1 SLITRK1 SLITRK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LRRC4BLeucine rich repeat containing 4B. (715 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
GRM5Glutamate metabotropic receptor 5. (1185 aa)
GRIN3BGlutamate ionotropic receptor NMDA type subunit 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1028 aa)
DCCDCC netrin 1 receptor. (1490 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2194 aa)
LRFN5Leucine rich repeat and fibronectin type III domain containing 5. (717 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (424 aa)
LRFN2Leucine rich repeat and fibronectin type III domain containing 2. (786 aa)
ADAM22ADAM metallopeptidase domain 22. (974 aa)
CLSTN3Calsyntenin 3. (1049 aa)
RGS7BPRegulator of G protein signaling 7 binding protein. (280 aa)
LRRC4Leucine rich repeat containing 4. (652 aa)
LRFN1Leucine rich repeat and fibronectin type III domain containing 1. (835 aa)
PLPPR4Phospholipid phosphatase related 4. (763 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa)
LIN7AProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (233 aa)
SIGMAR1Sigma non-opioid intracellular receptor 1. (267 aa)
SYNJ2BPSynaptojanin 2 binding protein. (145 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (300 aa)
SORCS3Sortilin related VPS10 domain containing receptor 3. (1222 aa)
GSG1LGSG1 like. (376 aa)
PRRT1Proline rich transmembrane protein 1. (305 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1216 aa)
SHISA9Shisa family member 9. (425 aa)
LIN7CProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (197 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C. (872 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (754 aa)
LIN7BProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (207 aa)
SYNDIG1Synapse differentiation inducing 1. (264 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
ADCY1Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1197 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (321 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D. (1333 aa)
RGS9Regulator of G protein signaling 9. (639 aa)
KCNH1Uncharacterized protein. (987 aa)
NPTNNeuroplastin. (471 aa)
SLITRK3SLIT and NTRK like family member 3. (980 aa)
ABHD17AAbhydrolase domain containing 17A. (310 aa)
CLSTN2Calsyntenin 2. (955 aa)
GRID2Glutamate ionotropic receptor delta type subunit 2. (1007 aa)
DAGLADiacylglycerol lipase alpha. (1041 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1497 aa)
ABHD17CAbhydrolase domain containing 17C. (365 aa)
LRRC4CLeucine rich repeat containing 4C. (640 aa)
LRFN4Leucine rich repeat and fibronectin type III domain containing 4. (748 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (426 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
NETO1Neuropilin and tolloid like 1. (533 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
MPP2Membrane palmitoylated protein 2; Belongs to the MAGUK family. (569 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (906 aa)
GRM1Glutamate metabotropic receptor 1. (1192 aa)
GRID1Glutamate ionotropic receptor delta type subunit 1. (1009 aa)
SLITRK1SLIT and NTRK like family member 1. (696 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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