STRINGSTRING
OTOF OTOF VPS11 VPS11 RAB8B RAB8B STX19 STX19 TRARG1 TRARG1 STX2 STX2 RAB13 RAB13 RAB15 RAB15 SNCA SNCA RAB8A RAB8A STXBP1 STXBP1 SNAP29 SNAP29 STXBP3 STXBP3 SNAPIN SNAPIN RAB3D RAB3D SCFD2 SCFD2 A0A4W2EU02 A0A4W2EU02 PSEN1 PSEN1 PLEK PLEK STXBP2 STXBP2 SNAP23 SNAP23 RAB3C RAB3C VPS18 VPS18 P2RX1 P2RX1 STX11 STX11 YKT6 YKT6 EXOC4 EXOC4 UNC13B UNC13B STX1B STX1B EXOC6 EXOC6 SCRIB SCRIB RAB3B RAB3B UNC13A UNC13A RAB3A RAB3A RAB12 RAB12 LRRC1 LRRC1 STX1A STX1A SYK SYK SNAP47 SNAP47 NLGN1 NLGN1 UNC13C UNC13C DMTN DMTN SV2A SV2A RAB10 RAB10 RABEPK RABEPK SNAP25 SNAP25 PPFIA3 PPFIA3 EXOC6B EXOC6B CFTR CFTR STX3 STX3 EXOC2 EXOC2 UNC13D UNC13D CTBP2 CTBP2 RAB44 RAB44 PRRT2 PRRT2 STX4 STX4 ERC2 ERC2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
OTOFOtoferlin. (1998 aa)
VPS11Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (941 aa)
RAB8BRAB8B, member RAS oncogene family. (207 aa)
STX19Syntaxin 19; Belongs to the syntaxin family. (292 aa)
TRARG1Trafficking regulator of GLUT4 (SLC2A4) 1. (177 aa)
STX2Syntaxin 2; Belongs to the syntaxin family. (317 aa)
RAB13Uncharacterized protein. (203 aa)
RAB15RAB15, member RAS oncogene family. (237 aa)
SNCAAlpha-synuclein; Belongs to the synuclein family. (140 aa)
RAB8ARAB8A, member RAS oncogene family. (207 aa)
STXBP1Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (603 aa)
SNAP29Synaptosome associated protein 29. (258 aa)
STXBP3Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (576 aa)
SNAPINSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
RAB3DRAB3D, member RAS oncogene family. (320 aa)
SCFD2Sec1 family domain containing 2; Belongs to the STXBP/unc-18/SEC1 family. (684 aa)
A0A4W2EU02t-SNARE coiled-coil homology domain-containing protein. (161 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (478 aa)
PLEKPleckstrin. (348 aa)
STXBP2Syntaxin binding protein 2; Belongs to the STXBP/unc-18/SEC1 family. (593 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa)
RAB3CRAB3C, member RAS oncogene family. (227 aa)
VPS18VPS18 core subunit of CORVET and HOPS complexes. (973 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
STX11Syntaxin 11; Belongs to the syntaxin family. (287 aa)
YKT6YKT6 v-SNARE homolog; Belongs to the synaptobrevin family. (198 aa)
EXOC4Exocyst complex component 4. (976 aa)
UNC13BUncharacterized protein. (4262 aa)
STX1BSyntaxin 1B; Belongs to the syntaxin family. (314 aa)
EXOC6Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (818 aa)
SCRIBScribble planar cell polarity protein. (1603 aa)
RAB3BRAB3B, member RAS oncogene family. (219 aa)
UNC13AUnc-13 homolog A. (1720 aa)
RAB3ARAB3A, member RAS oncogene family. (220 aa)
RAB12RAB12, member RAS oncogene family. (326 aa)
LRRC1Leucine rich repeat containing 1. (762 aa)
STX1ASyntaxin 1A. (373 aa)
SYKTyrosine-protein kinase. (628 aa)
SNAP47Synaptosome associated protein 47. (480 aa)
NLGN1Neuroligin 1. (823 aa)
UNC13CUnc-13 homolog C. (2215 aa)
DMTNDematin actin binding protein. (467 aa)
SV2ASynaptic vesicle glycoprotein 2A. (742 aa)
RAB10RAB10, member RAS oncogene family. (200 aa)
RABEPKRab9 effector protein with kelch motifs. (372 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
PPFIA3PTPRF interacting protein alpha 3. (1194 aa)
EXOC6BExocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (815 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1481 aa)
STX3Syntaxin 3; Belongs to the syntaxin family. (359 aa)
EXOC2Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (923 aa)
UNC13DUnc-13 homolog D. (1095 aa)
CTBP2C-terminal binding protein 2. (972 aa)
RAB44RAB44, member RAS oncogene family. (984 aa)
PRRT2Proline rich transmembrane protein 2. (398 aa)
STX4Syntaxin 4; Belongs to the syntaxin family. (447 aa)
ERC2ELKS/RAB6-interacting/CAST family member 2. (1010 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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