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A0A4W2C0Y8 | Reverse transcriptase domain-containing protein. (762 aa) | ||||
NME1 | Nucleoside diphosphate kinase. (152 aa) | ||||
NEIL3 | Nei like DNA glycosylase 3. (620 aa) | ||||
DNASE1L3 | Deoxyribonuclease; Belongs to the DNase I family. (309 aa) | ||||
NEIL1 | Nei like DNA glycosylase 1. (390 aa) | ||||
CECR2 | CECR2 histone acetyl-lysine reader. (1375 aa) | ||||
PGBD5 | PiggyBac transposable element derived 5. (525 aa) | ||||
MSH5 | DNA_MISMATCH_REPAIR_2 domain-containing protein. (832 aa) | ||||
A0A4W2C4K5 | RECA_2 domain-containing protein. (525 aa) | ||||
DNTT | DNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. (509 aa) | ||||
ALKBH2 | AlkB homolog 2, alpha-ketoglutarate dependent dioxygenase. (278 aa) | ||||
RECQL5 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (987 aa) | ||||
A0A4W2C7A9 | Reverse transcriptase domain-containing protein. (704 aa) | ||||
A0A4W2C8Q6 | Reverse transcriptase domain-containing protein. (338 aa) | ||||
POLG2 | DNA polymerase gamma 2, accessory subunit. (485 aa) | ||||
FSBP | Uncharacterized protein. (966 aa) | ||||
DICER1 | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. (1998 aa) | ||||
ENDOV | Endonuclease V. (399 aa) | ||||
CHD2 | Uncharacterized protein. (1827 aa) | ||||
A0A4W2CBX4 | Uncharacterized protein. (152 aa) | ||||
FANCM | FA complementation group M. (2084 aa) | ||||
POLN | DNA polymerase nu. (791 aa) | ||||
IGHMBP2 | Immunoglobulin mu DNA binding protein 2. (981 aa) | ||||
SUB1 | SUB1 regulator of transcription. (178 aa) | ||||
TERT | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1125 aa) | ||||
POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2289 aa) | ||||
XRCC1 | X-ray repair cross complementing 1. (692 aa) | ||||
ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit. (351 aa) | ||||
A0A4W2CHD7 | Reverse transcriptase domain-containing protein. (689 aa) | ||||
CHD7 | Chromodomain helicase DNA binding protein 7. (2990 aa) | ||||
LIG1 | DNA ligase. (1303 aa) | ||||
RPS3 | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (281 aa) | ||||
A0A4W2CII0 | Uncharacterized protein. (678 aa) | ||||
TOP2B | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1619 aa) | ||||
MCM4 | DNA helicase; Belongs to the MCM family. (836 aa) | ||||
TERF1 | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (436 aa) | ||||
POLD1 | DNA polymerase. (1106 aa) | ||||
TOP3B | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (861 aa) | ||||
XRCC5 | X-ray repair cross complementing 5. (813 aa) | ||||
SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (937 aa) | ||||
ALKBH3 | AlkB homolog 3, alpha-ketoglutaratedependent dioxygenase. (286 aa) | ||||
ACACB | Acetyl-CoA carboxylase beta. (2455 aa) | ||||
POLG | DNA polymerase gamma, catalytic subunit. (1217 aa) | ||||
A0A4W2CRB3 | BRCT domain-containing protein. (169 aa) | ||||
BPTF | Bromodomain PHD finger transcription factor. (3194 aa) | ||||
DSCC1 | DNA replication and sister chromatid cohesion 1. (389 aa) | ||||
INO80 | INO80 complex ATPase subunit. (1584 aa) | ||||
RBBP4 | RB binding protein 4, chromatin remodeling factor. (425 aa) | ||||
REV1 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1253 aa) | ||||
SMC5 | SMC_N domain-containing protein. (1197 aa) | ||||
PIF1 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (649 aa) | ||||
SPO11 | SPO11 initiator of meiotic double stranded breaks. (395 aa) | ||||
SHPRH | SNF2 histone linker PHD RING helicase. (1689 aa) | ||||
A0A4W2CYF2 | PWWP domain-containing protein. (159 aa) | ||||
CHD1 | Chromodomain helicase DNA binding protein 1. (1710 aa) | ||||
DDX1 | DEAD-box helicase 1. (740 aa) | ||||
RAD51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa) | ||||
ERCC6 | ERCC excision repair 6, chromatin remodeling factor. (1544 aa) | ||||
DCLRE1C | DNA cross-link repair 1C. (710 aa) | ||||
A0A4W2D2X3 | Zinc-hook domain-containing protein. (1440 aa) | ||||
DCLRE1B | DNA cross-link repair 1B. (542 aa) | ||||
MGME1 | Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA- primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair; Belongs to the MGME1 family. (342 aa) | ||||
ERCC6L2 | Uncharacterized protein. (1558 aa) | ||||
SMUG1 | Single-strand-selective monofunctional uracil-DNA glycosylase 1. (295 aa) | ||||
DNASE1L2 | Deoxyribonuclease; Belongs to the DNase I family. (278 aa) | ||||
RFC3 | Replication factor C subunit 3. (356 aa) | ||||
DNASE1 | Deoxyribonuclease; Belongs to the DNase I family. (282 aa) | ||||
OGG1 | 8-oxoguanine DNA glycosylase. (345 aa) | ||||
CHTF18 | Chromosome transmission fidelity factor 18. (978 aa) | ||||
NAV2 | Neuron navigator 2. (2451 aa) | ||||
WRNIP1 | WRN helicase interacting protein 1. (638 aa) | ||||
MCM2 | DNA helicase; Belongs to the MCM family. (902 aa) | ||||
BRIP1 | BRCA1 interacting protein C-terminal helicase 1. (1172 aa) | ||||
MBD4 | Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein. (559 aa) | ||||
RAD51C | RAD51 paralog C. (442 aa) | ||||
MLH1 | MutL homolog 1. (758 aa) | ||||
KIAA1257 | KIAA1257. (412 aa) | ||||
A0A4W2BUF7 | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (531 aa) | ||||
C17orf64 | Chromosome 17 open reading frame 64. (234 aa) | ||||
MUS81 | MUS81 structure-specific endonuclease subunit. (552 aa) | ||||
WRN | WRN RecQ like helicase. (1409 aa) | ||||
C11orf80 | Chromosome 11 open reading frame 80. (566 aa) | ||||
MCM3 | DNA helicase; Belongs to the MCM family. (808 aa) | ||||
APEX1 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (318 aa) | ||||
DNA2 | DNA replication helicase/nuclease 2. (1061 aa) | ||||
ERCC2 | ERCC excision repair 2, TFIIH core complex helicase subunit. (800 aa) | ||||
MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa) | ||||
GTF2F2 | General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa) | ||||
MCM5 | DNA helicase; Belongs to the MCM family. (892 aa) | ||||
DNMT3B | DNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (862 aa) | ||||
SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1639 aa) | ||||
TM4SF19 | Uncharacterized protein. (209 aa) | ||||
RAD51B | RAD51 paralog B. (350 aa) | ||||
HAUS3 | HAUS augmin like complex subunit 3. (601 aa) | ||||
HFM1 | Helicase for meiosis 1. (1437 aa) | ||||
FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) | ||||
HELB | DNA helicase B. (1136 aa) | ||||
RAD54L2 | RAD54 like 2. (1468 aa) | ||||
MCM8 | MCM domain-containing protein; Belongs to the MCM family. (832 aa) | ||||
CDK7 | Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa) | ||||
SUPV3L1 | Suv3 like RNA helicase. (787 aa) | ||||
ISG20 | Interferon stimulated exonuclease gene 20. (171 aa) | ||||
CEP41 | Centrosomal protein 41. (373 aa) | ||||
DNMT1 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1708 aa) | ||||
EXO1 | Exonuclease 1. (835 aa) | ||||
TERF2 | Telomeric repeat binding factor 2. (543 aa) | ||||
CHD3 | Chromodomain helicase DNA binding protein 3. (2059 aa) | ||||
A0A4W2E4N5 | Uncharacterized protein. (213 aa) | ||||
A0A4W2E4U3 | Reverse transcriptase domain-containing protein. (729 aa) | ||||
MSH6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1361 aa) | ||||
SRCAP | Uncharacterized protein. (3291 aa) | ||||
A0A4W2E8J1 | Uncharacterized protein. (700 aa) | ||||
MCM9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1139 aa) | ||||
DQX1 | DEAQ-box RNA dependent ATPase 1. (719 aa) | ||||
MPHOSPH9 | M-phase phosphoprotein 9. (1182 aa) | ||||
DFFB | DNA fragmentation factor subunit beta. (341 aa) | ||||
EP400 | E1A binding protein p400. (3096 aa) | ||||
A0A4W2EBN3 | Reverse transcriptase domain-containing protein. (340 aa) | ||||
ASCC3 | Activating signal cointegrator 1 complex subunit 3. (2201 aa) | ||||
GEN1 | GEN1 Holliday junction 5' flap endonuclease. (906 aa) | ||||
A0A4W2EEB8 | Reverse transcriptase domain-containing protein. (350 aa) | ||||
TOP1MT | DNA topoisomerase I mitochondrial. (560 aa) | ||||
FAN1 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1228 aa) | ||||
A0A4W2EGX9 | Uncharacterized protein. (502 aa) | ||||
CHD4 | Uncharacterized protein. (1920 aa) | ||||
HMGA2 | Uncharacterized protein. (109 aa) | ||||
PMS2 | MutL_C domain-containing protein. (461 aa) | ||||
CHD9 | Chromodomain helicase DNA binding protein 9. (2900 aa) | ||||
FTO | FTO alpha-ketoglutarate dependent dioxygenase. (521 aa) | ||||
RAD9B | Cell cycle checkpoint control protein; Belongs to the rad9 family. (417 aa) | ||||
RAD17 | RAD17 checkpoint clamp loader component. (708 aa) | ||||
REV3L | REV3 like, DNA directed polymerase zeta catalytic subunit. (3133 aa) | ||||
CHD5 | Chromodomain helicase DNA binding protein 5. (1953 aa) | ||||
ERCC5 | ERCC excision repair 5, endonuclease. (1201 aa) | ||||
TEP1 | Telomerase associated protein 1. (2656 aa) | ||||
POLQ | DNA polymerase theta. (2585 aa) | ||||
CHD8 | Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2583 aa) | ||||
A0A4W2EPQ5 | Reverse transcriptase domain-containing protein. (253 aa) | ||||
ALKBH1 | AlkB homolog 1, histone H2A dioxygenase. (389 aa) | ||||
MLH3 | MutL homolog 3. (1514 aa) | ||||
TTF2 | Transcription termination factor 2. (1215 aa) | ||||
XRCC2 | X-ray repair cross complementing 2. (319 aa) | ||||
CHD1L | Chromodomain helicase DNA binding protein 1 like. (897 aa) | ||||
HELQ | Helicase, POLQ like. (1092 aa) | ||||
A0A4W2EWF7 | Reverse transcriptase domain-containing protein. (683 aa) | ||||
RFC1 | Replication factor C subunit 1. (1146 aa) | ||||
HLTF | Helicase like transcription factor. (1009 aa) | ||||
ANKLE1 | Ankyrin repeat and LEM domain containing 1. (667 aa) | ||||
MCM6 | DNA helicase; Belongs to the MCM family. (821 aa) | ||||
A0A4W2F279 | Uncharacterized protein. (242 aa) | ||||
TDG | Thymine DNA glycosylase. (454 aa) | ||||
PMS1 | PMS1 homolog 1, mismatch repair system component. (915 aa) | ||||
DNASE2B | Deoxyribonuclease 2 beta. (357 aa) | ||||
A0A4W2F465 | Uncharacterized protein. (157 aa) | ||||
APLF | Aprataxin and PNKP like factor. (509 aa) | ||||
TDP2 | Tyrosyl-DNA phosphodiesterase 2. (364 aa) | ||||
UPF1 | UPF1 RNA helicase and ATPase. (1127 aa) | ||||
TOP1 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (769 aa) | ||||
ERCC4 | ERCC excision repair 4, endonuclease catalytic subunit. (916 aa) | ||||
CHD6 | Chromodomain helicase DNA binding protein 6. (2721 aa) | ||||
TOP3A | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1002 aa) | ||||
ENDOG | Endonuclease. (299 aa) | ||||
PTGES3 | CS domain-containing protein. (160 aa) | ||||
METTL4 | Methyltransferase like 4; Belongs to the MT-A70-like family. (470 aa) | ||||
PLD3 | Phospholipase D family member 3. (490 aa) | ||||
SMC3 | Structural maintenance of chromosomes protein. (1217 aa) | ||||
RTEL1 | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1266 aa) | ||||
SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1572 aa) | ||||
POLM | DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (488 aa) | ||||
RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa) | ||||
DHX9 | DExH-box helicase 9. (1287 aa) | ||||
DMC1 | DNA meiotic recombinase 1; Belongs to the RecA family. (340 aa) | ||||
FBH1 | F-box DNA helicase 1. (1045 aa) | ||||
TATDN1 | TatD DNase domain containing 1. (331 aa) | ||||
POLL | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (575 aa) | ||||
MSH3 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1118 aa) | ||||
XRCC6 | X-ray repair cross complementing 6. (657 aa) | ||||
A0A4W2E1T5 | Uncharacterized protein. (76 aa) | ||||
SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (1051 aa) | ||||
A0A4W2DZE6 | Reverse transcriptase domain-containing protein. (346 aa) | ||||
REXO2 | RNA exonuclease 2. (237 aa) | ||||
BLM | BLM RecQ like helicase. (1430 aa) | ||||
TOP2A | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1532 aa) | ||||
DDX11 | DEAD/H-box helicase 11. (1012 aa) | ||||
MUTYH | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (526 aa) | ||||
RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) | ||||
EXO5 | Exonuclease 5. (370 aa) | ||||
APEX2 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (513 aa) | ||||
RSF1 | Remodeling and spacing factor 1. (1451 aa) | ||||
DCLRE1A | DNA cross-link repair 1A. (1045 aa) | ||||
RAD51D | RAD51 paralog D. (418 aa) | ||||
LIG3 | DNA ligase. (943 aa) | ||||
A0A4W2DSD6 | Uncharacterized protein. (513 aa) | ||||
POLH | DNA polymerase eta. (711 aa) | ||||
RFC2 | Replication factor C subunit 2. (352 aa) | ||||
POLI | DNA polymerase iota. (760 aa) | ||||
A0A4W2DQT9 | TFIIF_beta domain-containing protein. (115 aa) | ||||
NTHL1 | Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (313 aa) | ||||
RBBP8 | RB binding protein 8, endonuclease. (859 aa) | ||||
EXOG | Exo/endonuclease G. (368 aa) | ||||
ERCC3 | ERCC excision repair 3, TFIIH core complex helicase subunit. (780 aa) | ||||
MSH4 | MutS homolog 4. (934 aa) | ||||
SLX1A | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. (366 aa) | ||||
DNASE2 | Deoxyribonuclease 2, lysosomal. (365 aa) | ||||
ATAD5 | ATPase family AAA domain containing 5. (1893 aa) | ||||
G3BP1 | G3BP stress granule assembly factor 1. (465 aa) | ||||
DDX3X | DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (645 aa) | ||||
MEIOB | Meiosis specific with OB-fold. (472 aa) | ||||
ALKBH4 | AlkB homolog 4, lysine demethylase. (303 aa) | ||||
MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) | ||||
TDP1 | Tyrosyl-DNA phosphodiesterase 1. (690 aa) | ||||
RECQL | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (780 aa) | ||||
RAD54L | RAD54 like. (749 aa) | ||||
A0A4W2DG76 | Reverse transcriptase domain-containing protein. (247 aa) | ||||
DNMT3A | DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (957 aa) | ||||
DHX36 | DEAH-box helicase 36. (1010 aa) | ||||
ZRANB3 | Zinc finger RANBP2-type containing 3. (1096 aa) | ||||
SMARCAD1 | Uncharacterized protein. (1029 aa) | ||||
N6AMT1 | N-6 adenine-specific DNA methyltransferase 1. (260 aa) | ||||
A0A4W2DEF9 | General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (257 aa) | ||||
A0A4W2DC90 | Reverse transcriptase domain-containing protein. (732 aa) | ||||
APTX | Aprataxin. (347 aa) | ||||
POLK | DNA polymerase kappa. (911 aa) | ||||
PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (326 aa) | ||||
A0A4W2D7Q2 | Reverse transcriptase domain-containing protein. (383 aa) | ||||
RFC4 | Replication factor C subunit 4. (364 aa) | ||||
MRE11 | MRE11 homolog, double strand break repair nuclease; Belongs to the MRE11/RAD32 family. (943 aa) | ||||
PRIMPOL | Primase and DNA directed polymerase. (555 aa) |