STRINGSTRING
A0A4W2BK72 A0A4W2BK72 A0A4W2BMI7 A0A4W2BMI7 LOC113888605 LOC113888605 CD83 CD83 TMEM98 TMEM98 IRF4 IRF4 CTNNB1 CTNNB1 AZI2 AZI2 PTPN2 PTPN2 CD3E CD3E NRARP NRARP FUT7 FUT7 PPP3CB PPP3CB PRTN3 PRTN3 BCL2 BCL2 A0A4W2BXD2 A0A4W2BXD2 RUNX2 RUNX2 CD3D CD3D BAK1 BAK1 TBX21 TBX21 MALT1 MALT1 TUSC2 TUSC2 IL21 IL21 EP300 EP300 A0A4W2C1R2 A0A4W2C1R2 LY6D LY6D RAB44 RAB44 CRACR2A CRACR2A YY1 YY1 PATZ1 PATZ1 JAG2 JAG2 GPS2 GPS2 THOC5 THOC5 PIK3R1 PIK3R1 CD79B CD79B CDH17 CDH17 CBFB CBFB CLEC4E CLEC4E CD8A CD8A TCIRG1 TCIRG1 TRAF3IP2 TRAF3IP2 FADD FADD STAT5B STAT5B RIPK2 RIPK2 PTGER4 PTGER4 CCR7 CCR7 IL7R IL7R POU2F2 POU2F2 FZD7 FZD7 CHD7 CHD7 KAT7 KAT7 TGFB1 TGFB1 ENTPD7 ENTPD7 SRF SRF BCL3 BCL3 IL7 IL7 BLNK BLNK LTBR LTBR TPD52 TPD52 A0A4W2CP79 A0A4W2CP79 CD4 CD4 ONECUT1 ONECUT1 A0A4W2CR26 A0A4W2CR26 A0A4W2CRB3 A0A4W2CRB3 DCSTAMP DCSTAMP A0A4W2CRW3 A0A4W2CRW3 RORA RORA DOCK2 DOCK2 ITPKB ITPKB MTOR MTOR ABL1 ABL1 GAS6 GAS6 RSAD2 RSAD2 GLI3 GLI3 ZNF683 ZNF683 DLL4 DLL4 GPR18 GPR18 A0A4W2CWS2 A0A4W2CWS2 A0A4W2CWU5 A0A4W2CWU5 A0A4W2CWV7 A0A4W2CWV7 WNT10B WNT10B A0A4W2CX00 A0A4W2CX00 A0A4W2CX03 A0A4W2CX03 LOC113896968 LOC113896968 LMBR1L LMBR1L GATA3 GATA3 LEP LEP AXL AXL TYRO3 TYRO3 DLL1 DLL1 TNFSF8 TNFSF8 LOC113896981 LOC113896981 A0A4W2D155 A0A4W2D155 LOC113897798 LOC113897798 SOX13 SOX13 THEMIS THEMIS DCLRE1C DCLRE1C MERTK MERTK FZD5 FZD5 A0A4W2D326 A0A4W2D326 EZH2 EZH2 A0A4W2D4F2 A0A4W2D4F2 PAX1 PAX1 ADA ADA PSMB11 PSMB11 BCL6 BCL6 ATF2 ATF2 ZFP36L1 ZFP36L1 STAT6 STAT6 A0A4W2D9C0 A0A4W2D9C0 PRR7 PRR7 GPR89A GPR89A ZBTB7B ZBTB7B LOC113885454 LOC113885454 HLX HLX KIT KIT MFNG MFNG IL18R1 IL18R1 LEPR LEPR A0A4W2DGC7 A0A4W2DGC7 TRPM2 TRPM2 IL6R IL6R EGR1 EGR1 A0A4W2DJH4 A0A4W2DJH4 A0A4W2DJH9 A0A4W2DJH9 SOX4 SOX4 ZBTB7A ZBTB7A PKNOX1 PKNOX1 LYL1 LYL1 FNIP1 FNIP1 SYK SYK A0A4W2DP99 A0A4W2DP99 EOMES EOMES FLT3 FLT3 TSC1 TSC1 FOXN1 FOXN1 ATM ATM IKZF3 IKZF3 MED1 MED1 GBA GBA ERBB2 ERBB2 GPR68 GPR68 VEGFA VEGFA ADGRG3 ADGRG3 IL31RA IL31RA NKX2-3 NKX2-3 LEF1 LEF1 IL12B IL12B CEBPG CEBPG LFNG LFNG CD28 CD28 BCL11B BCL11B A0A4W2E7C9 A0A4W2E7C9 RAG1 RAG1 TGFBR2 TGFBR2 CCR9 CCR9 STAT3 STAT3 STAT5A STAT5A MS4A1 MS4A1 LYN LYN RC3H1 RC3H1 PTPRC PTPRC BMP4 BMP4 IRF8 IRF8 MR1 MR1 FASN FASN ATG5 ATG5 RELB RELB SPI1 SPI1 ZBTB46 ZBTB46 LOC113897812 LOC113897812 ZAP70 ZAP70 A0A4W2EMJ2 A0A4W2EMJ2 A0A4W2EMK8 A0A4W2EMK8 A0A4W2EML2 A0A4W2EML2 A0A4W2EML3 A0A4W2EML3 A0A4W2EMM2 A0A4W2EMM2 LOC113896984 LOC113896984 A0A4W2EMP1 A0A4W2EMP1 MAFB MAFB IFNK IFNK CCR6 CCR6 BLK BLK BRAF BRAF TSHR TSHR PDE1B PDE1B PSEN1 PSEN1 CSF2 CSF2 CSF1 CSF1 RIPK3 RIPK3 IL4 IL4 A0A4W2ET73 A0A4W2ET73 SHH SHH NOTCH2 NOTCH2 PTK2B PTK2B IL12A IL12A ITGB6 ITGB6 IL6 IL6 ITGB8 ITGB8 SEMA4A SEMA4A SLAMF6 SLAMF6 MYH9 MYH9 FBXO7 FBXO7 LY9 LY9 ITK ITK AIRE AIRE CAMK4 CAMK4 JMJD6 JMJD6 PLCG2 PLCG2 IL15 IL15 DCAF1 DCAF1 TREM2 TREM2 TCF7 TCF7 LINC01862 LINC01862 VAV1 VAV1 RHOA RHOA CDK6 CDK6 TMEM176B TMEM176B CLEC4D CLEC4D BATF2 BATF2 CTSV CTSV CARD11 CARD11 CD79A CD79A IRF1 IRF1 SLAMF1 SLAMF1 POU2AF1 POU2AF1 PREX1 PREX1 CD74 CD74 CCL19 CCL19 CD19 CD19 MSH2 MSH2 TOX TOX ITFG2 ITFG2 TNFSF13B TNFSF13B LOC113897811 LOC113897811 LOC113897789 LOC113897789 A0A4W2GUX8 A0A4W2GUX8 LOC113897795 LOC113897795 BATF BATF BATF3 BATF3 LGALS1 LGALS1 ARMC5 ARMC5 SP3 SP3 ZBTB1 ZBTB1 FOXP3 FOXP3 LOC113888606 LOC113888606 CLEC4G CLEC4G LOC113891018 LOC113891018 NTRK1 NTRK1 IKZF1 IKZF1 LCK LCK RABL3 RABL3 PLCL2 PLCL2 LRRC8A LRRC8A NFIL3 NFIL3 PTPN22 PTPN22 RAG2 RAG2 TP53 TP53 WNT1 WNT1 RC3H2 RC3H2 JUN JUN IRF2BP2 IRF2BP2 LOC113896989 LOC113896989 ZFP36L2 ZFP36L2 HECTD1 HECTD1 GPR183 GPR183 STK11 STK11 LOC113888607 LOC113888607
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A4W2BK72Uncharacterized protein. (172 aa)
A0A4W2BMI7Uncharacterized protein. (195 aa)
LOC113888605Uncharacterized protein. (195 aa)
CD83CD83 molecule. (216 aa)
TMEM98Transmembrane protein 98. (318 aa)
IRF4Interferon regulatory factor 4. (451 aa)
CTNNB1Catenin beta 1. (774 aa)
AZI25-azacytidine induced 2. (393 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (416 aa)
CD3ECD3e molecule. (197 aa)
NRARPNOTCH regulated ankyrin repeat protein. (114 aa)
FUT7Fucosyltransferase 7. (342 aa)
PPP3CBSerine/threonine-protein phosphatase. (524 aa)
PRTN3Proteinase 3; Belongs to the peptidase S1 family. (256 aa)
BCL2BCL2 apoptosis regulator. (229 aa)
A0A4W2BXD2Uncharacterized protein. (517 aa)
RUNX2RUNX family transcription factor 2. (527 aa)
CD3DCD3d molecule. (167 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
TBX21T-box transcription factor 21. (532 aa)
MALT1MALT1 paracaspase. (850 aa)
TUSC2Tumor suppressor 2, mitochondrial calcium regulator. (110 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (153 aa)
EP300E1A binding protein p300. (2411 aa)
A0A4W2C1R2Uncharacterized protein. (498 aa)
LY6DLymphocyte antigen 6 family member D. (125 aa)
RAB44RAB44, member RAS oncogene family. (984 aa)
CRACR2ACalcium release activated channel regulator 2A. (723 aa)
YY1YY1 transcription factor. (415 aa)
PATZ1POZ/BTB and AT hook containing zinc finger 1. (687 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1239 aa)
GPS2G protein pathway suppressor 2. (327 aa)
THOC5THO complex 5. (732 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
CD79BCD79b molecule. (230 aa)
CDH17Cadherin 17. (832 aa)
CBFBCore-binding factor subunit beta. (187 aa)
CLEC4EC-type lectin domain family 4 member E. (211 aa)
CD8ACD8a molecule. (242 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
TRAF3IP2TRAF3 interacting protein 2. (596 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (209 aa)
STAT5BSignal transducer and activator of transcription. (787 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (539 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (492 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (415 aa)
IL7RInterleukin 7 receptor. (459 aa)
POU2F2POU domain protein. (589 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2990 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa)
TGFB1Transforming growth factor beta 1. (443 aa)
ENTPD7Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (604 aa)
SRFSerum response factor. (509 aa)
BCL3BCL3 transcription coactivator. (454 aa)
IL7Interleukin 7. (185 aa)
BLNKB cell linker. (480 aa)
LTBRLymphotoxin beta receptor. (428 aa)
TPD52Uncharacterized protein. (385 aa)
A0A4W2CP79Annexin. (335 aa)
CD4CD4 molecule. (455 aa)
ONECUT1One cut domain family member. (712 aa)
A0A4W2CR26TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa)
A0A4W2CRB3BRCT domain-containing protein. (169 aa)
DCSTAMPDendrocyte expressed seven transmembrane protein. (510 aa)
A0A4W2CRW3Annexin. (346 aa)
RORARAR related orphan receptor A. (527 aa)
DOCK2Dedicator of cytokinesis 2; Belongs to the DOCK family. (1830 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (970 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
ABL1Tyrosine-protein kinase. (1151 aa)
GAS6Growth arrest specific 6. (671 aa)
RSAD2Radical S-adenosyl methionine domain containing 2. (363 aa)
GLI3GLI family zinc finger 3. (1587 aa)
ZNF683Uncharacterized protein. (481 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
GPR18G protein-coupled receptor 18; Belongs to the G-protein coupled receptor 1 family. (332 aa)
A0A4W2CWS2Uncharacterized protein. (154 aa)
A0A4W2CWU5Uncharacterized protein. (190 aa)
A0A4W2CWV7Uncharacterized protein. (189 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (433 aa)
A0A4W2CX00Uncharacterized protein. (189 aa)
A0A4W2CX03Uncharacterized protein. (254 aa)
LOC113896968Uncharacterized protein. (195 aa)
LMBR1LLimb development membrane protein 1 like; Belongs to the LIMR family. (489 aa)
GATA3GATA binding protein 3. (467 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
AXLAXL receptor tyrosine kinase. (878 aa)
TYRO3TYRO3 protein tyrosine kinase. (889 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (722 aa)
TNFSF8TNF superfamily member 8; Belongs to the tumor necrosis factor family. (234 aa)
LOC113896981Uncharacterized protein. (193 aa)
A0A4W2D155Uncharacterized protein. (153 aa)
LOC113897798Uncharacterized protein. (195 aa)
SOX13SRY-box transcription factor 13. (623 aa)
THEMISThymocyte selection associated. (642 aa)
DCLRE1CDNA cross-link repair 1C. (710 aa)
MERTKMER proto-oncogene, tyrosine kinase. (999 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
A0A4W2D326Uncharacterized protein. (165 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (779 aa)
A0A4W2D4F2AIG1-type G domain-containing protein. (297 aa)
PAX1Paired box 1. (593 aa)
ADAAdenosine deaminase. (391 aa)
PSMB11Proteasome subunit beta. (289 aa)
BCL6BCL6 transcription repressor. (706 aa)
ATF2Activating transcription factor 2. (447 aa)
ZFP36L1ZFP36 ring finger protein like 1. (323 aa)
STAT6Signal transducer and activator of transcription. (847 aa)
A0A4W2D9C0AIG1-type G domain-containing protein. (321 aa)
PRR7Proline rich 7, synaptic. (269 aa)
GPR89AUncharacterized protein. (544 aa)
ZBTB7BZinc finger and BTB domain containing 7B. (538 aa)
LOC113885454Myb-like domain-containing protein. (2239 aa)
HLXH2.0 like homeobox. (486 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
MFNGBeta-1,3-N-acetylglucosaminyltransferase. (320 aa)
IL18R1Interleukin 18 receptor 1. (538 aa)
LEPRLeptin receptor. (1165 aa)
A0A4W2DGC7Uncharacterized protein. (186 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1499 aa)
IL6RInterleukin 6 receptor. (464 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (542 aa)
A0A4W2DJH4Uncharacterized protein. (189 aa)
A0A4W2DJH9Uncharacterized protein. (195 aa)
SOX4SRY-box transcription factor 4. (501 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (567 aa)
PKNOX1PBX/knotted 1 homeobox 1. (436 aa)
LYL1LYL1 basic helix-loop-helix family member. (305 aa)
FNIP1Folliculin interacting protein 1. (1163 aa)
SYKTyrosine-protein kinase. (628 aa)
A0A4W2DP99AIG1-type G domain-containing protein. (333 aa)
EOMESEomesodermin. (701 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa)
TSC1TSC complex subunit 1. (1165 aa)
FOXN1Forkhead box N1. (644 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3054 aa)
IKZF3IKAROS family zinc finger 3. (509 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1575 aa)
GBAGlucosylceramidase. (536 aa)
ERBB2Erb-b2 receptor tyrosine kinase 2. (1710 aa)
GPR68G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (383 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (394 aa)
ADGRG3Adhesion G protein-coupled receptor G3; Belongs to the G-protein coupled receptor 2 family. (547 aa)
IL31RAInterleukin 31 receptor A. (717 aa)
NKX2-3NK2 homeobox 3. (367 aa)
LEF1Lymphoid enhancer binding factor 1. (430 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (327 aa)
CEBPGCCAAT enhancer binding protein gamma. (149 aa)
LFNGBeta-1,3-N-acetylglucosaminyltransferase. (380 aa)
CD28CD28 molecule. (265 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (903 aa)
A0A4W2E7C9TNF receptor-associated factor. (411 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa)
CCR9C-C motif chemokine receptor 9; Belongs to the G-protein coupled receptor 1 family. (367 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
MS4A1Membrane spanning 4-domains A1. (303 aa)
LYNTyrosine-protein kinase. (491 aa)
RC3H1Ring finger and CCCH-type domains 1. (1132 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1243 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
IRF8Interferon regulatory factor 8. (426 aa)
MR1Major histocompatibility complex, class I-related; Belongs to the MHC class I family. (340 aa)
FASNFatty acid synthase. (2515 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (214 aa)
RELBRELB proto-oncogene, NF-kB subunit. (647 aa)
SPI1Spi-1 proto-oncogene. (384 aa)
ZBTB46Zinc finger and BTB domain containing 46. (614 aa)
LOC113897812Uncharacterized protein. (186 aa)
ZAP70Tyrosine-protein kinase. (617 aa)
A0A4W2EMJ2Uncharacterized protein. (195 aa)
A0A4W2EMK8Uncharacterized protein. (195 aa)
A0A4W2EML2Uncharacterized protein. (186 aa)
A0A4W2EML3Uncharacterized protein. (189 aa)
A0A4W2EMM2Uncharacterized protein. (187 aa)
LOC113896984Uncharacterized protein. (190 aa)
A0A4W2EMP1Uncharacterized protein. (195 aa)
MAFBMAF bZIP transcription factor B. (348 aa)
IFNKInterferon kappa. (215 aa)
CCR6C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (375 aa)
BLKTyrosine-protein kinase. (524 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (805 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (763 aa)
PDE1BPhosphodiesterase. (584 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (478 aa)
CSF2Colony stimulating factor 2. (143 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (575 aa)
RIPK3Receptor interacting serine/threonine kinase 3. (504 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (135 aa)
A0A4W2ET73AIG1-type G domain-containing protein. (310 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (464 aa)
NOTCH2Notch receptor 2. (2471 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1008 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (240 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
IL6Interleukin 6. (208 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (772 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (851 aa)
SLAMF6SLAM family member 6. (352 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1986 aa)
FBXO7F-box protein 7. (522 aa)
LY9Lymphocyte antigen 9. (670 aa)
ITKTyrosine-protein kinase. (620 aa)
AIREAutoimmune regulator. (565 aa)
CAMK4Protein kinase domain-containing protein. (750 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (414 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1266 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (135 aa)
DCAF1DDB1 and CUL4 associated factor 1. (1507 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (244 aa)
TCF7Transcription factor 7. (473 aa)
LINC01862Long intergenic non-protein coding RNA 1862. (291 aa)
VAV1Vav guanine nucleotide exchange factor 1. (872 aa)
RHOARas homolog family member A. (193 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
TMEM176BTransmembrane protein 176B. (265 aa)
CLEC4DC-type lectin domain family 4 member D. (213 aa)
BATF2Basic leucine zipper ATF-like transcription factor 2. (275 aa)
CTSVCathepsin V; Belongs to the peptidase C1 family. (334 aa)
CARD11Caspase recruitment domain family member 11. (1154 aa)
CD79ACD79a molecule. (223 aa)
IRF1Interferon regulatory factor. (322 aa)
SLAMF1Ig-like domain-containing protein. (338 aa)
POU2AF1POU class 2 homeobox associating factor 1. (284 aa)
PREX1Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1653 aa)
CD74CD74 molecule. (268 aa)
CCL19C-C motif chemokine. (115 aa)
CD19CD19 molecule. (568 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa)
TOXThymocyte selection associated high mobility group box. (527 aa)
ITFG2Integrin alpha FG-GAP repeat containing 2. (444 aa)
TNFSF13BTNF superfamily member 13b; Belongs to the tumor necrosis factor family. (280 aa)
LOC113897811Uncharacterized protein. (186 aa)
LOC113897789Uncharacterized protein. (195 aa)
A0A4W2GUX8Uncharacterized protein. (186 aa)
LOC113897795Uncharacterized protein. (189 aa)
BATFBasic leucine zipper ATF-like transcription factor. (125 aa)
BATF3Basic leucine zipper ATF-like transcription factor 3. (122 aa)
LGALS1Galectin. (135 aa)
ARMC5Armadillo repeat containing 5. (940 aa)
SP3Sp3 transcription factor. (781 aa)
ZBTB1Zinc finger and BTB domain containing 1. (713 aa)
FOXP3Forkhead box P3. (454 aa)
LOC113888606Uncharacterized protein. (195 aa)
CLEC4GC-type lectin domain family 4 member G. (290 aa)
LOC113891018AIG1-type G domain-containing protein. (294 aa)
NTRK1Tyrosine-protein kinase receptor. (821 aa)
IKZF1IKAROS family zinc finger 1. (519 aa)
LCKTyrosine-protein kinase. (509 aa)
RABL3RAB, member of RAS oncogene family like 3. (236 aa)
PLCL2Phosphoinositide phospholipase C. (1118 aa)
LRRC8ALeucine rich repeat containing 8 VRAC subunit A. (810 aa)
NFIL3Nuclear factor, interleukin 3 regulated. (468 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (808 aa)
RAG2Recombination activating 2. (527 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (499 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
RC3H2Ring finger and CCCH-type domains 2. (1132 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (335 aa)
IRF2BP2Interferon regulatory factor 2 binding protein 2. (588 aa)
LOC113896989Uncharacterized protein. (186 aa)
ZFP36L2ZFP36 ring finger protein like 2. (485 aa)
HECTD1HECT domain E3 ubiquitin protein ligase 1. (2610 aa)
GPR183G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (360 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (438 aa)
LOC113888607Uncharacterized protein. (189 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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