STRINGSTRING
LRRC15 LRRC15 AKAP5 AKAP5 GPC1 GPC1 C2CD5 C2CD5 EPHA2 EPHA2 EFCAB7 EFCAB7 VTI1B VTI1B PLS1 PLS1 TREM2 TREM2 PTPN9 PTPN9 VAMP8 VAMP8 AKT1 AKT1 ZDHHC2 ZDHHC2 TXNDC11 TXNDC11 PIK3R2 PIK3R2 RAP1A RAP1A GRASP GRASP PID1 PID1 AGR2 AGR2 ADAM10 ADAM10 EPHA3 EPHA3 ITGB1 ITGB1 PPP2R5A PPP2R5A BBC3 BBC3 HRAS HRAS ABI3 ABI3 WNT3A WNT3A GPC2 GPC2 PRKCI PRKCI STAC3 STAC3 CIB1 CIB1 CD81 CD81 RHOG RHOG VIL1 VIL1 HECTD1 HECTD1 STX7 STX7 SPTBN1 SPTBN1 TGFB1 TGFB1 STX3 STX3 AKT2 AKT2 SHISA7 SHISA7 DAB2 DAB2 GOPC GOPC EGFR EGFR STAC STAC ZDHHC7 ZDHHC7 PIK3R1 PIK3R1 CEMIP CEMIP MESD MESD RANGRF RANGRF A0A4W2C5I5 A0A4W2C5I5 STX8 STX8 PICALM PICALM MYO1C MYO1C MIEF2 MIEF2 STAC2 STAC2 A0A4W2BZP2 A0A4W2BZP2 AR AR SLC7A11 SLC7A11 NHLRC1 NHLRC1 APPL1 APPL1 DAG1 DAG1 LZTFL1 LZTFL1 CSRP3 CSRP3 CLN3 CLN3 A0A4W2BND6 A0A4W2BND6 EZR EZR DLG1 DLG1 CRIPT CRIPT MMP14 MMP14 FRRS1L FRRS1L NUMB NUMB PDZK1 PDZK1 KCNB1 KCNB1 DMTN DMTN CDK5 CDK5 LDLRAP1 LDLRAP1 SQSTM1 SQSTM1 TNFAIP6 TNFAIP6 MRAP MRAP GSN GSN PDPK1 PDPK1 INPP5K INPP5K R3HDM1 R3HDM1 DPP10 DPP10 TCAF1 TCAF1 CLTC CLTC SLC51B SLC51B GPER1 GPER1 ERBB2 ERBB2 ACTB ACTB ATP2C1 ATP2C1 ITGA3 ITGA3 A0A4W2E2B7 A0A4W2E2B7 RHOQ RHOQ DLG2 DLG2 KIF5B KIF5B ATP2B4 ATP2B4 RER1 RER1 VPS4A VPS4A LGALS3 LGALS3 CLIP3 CLIP3 A0A4W2E9C2 A0A4W2E9C2 TMBIM1 TMBIM1 RAMP3 RAMP3 CACNG4 CACNG4 A0A4W2EBL9 A0A4W2EBL9 PKDCC PKDCC ITGB1BP1 ITGB1BP1 WNK3 WNK3 TNF TNF ARHGAP44 ARHGAP44 R3HDM2 R3HDM2 GPC5 GPC5 ARF6 ARF6 FYN FYN CHP1 CHP1 NKD2 NKD2 A0A4W2ESW9 A0A4W2ESW9 GPC6 GPC6 PRKN PRKN CNST CNST EPM2A EPM2A ARHGEF16 ARHGEF16 CRKL CRKL LRP1 LRP1 MFF MFF ACSL3 ACSL3 ZDHHC5 ZDHHC5 LRP4 LRP4 MRAP2 MRAP2 MIEF1 MIEF1 ANXA13 ANXA13
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LRRC15Leucine rich repeat containing 15. (584 aa)
AKAP5A-kinase anchoring protein 5. (428 aa)
GPC1Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (610 aa)
C2CD5C2 calcium dependent domain containing 5. (1137 aa)
EPHA2EPH receptor A2. (1007 aa)
EFCAB7EF-hand calcium binding domain 7. (629 aa)
VTI1BVesicle transport through interaction with t-SNAREs 1B. (232 aa)
PLS1Plastin 1. (630 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (244 aa)
PTPN9Protein tyrosine phosphatase non-receptor type 9. (593 aa)
VAMP8Vesicle associated membrane protein 8. (100 aa)
AKT1Non-specific serine/threonine protein kinase. (747 aa)
ZDHHC2Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (366 aa)
TXNDC11Thioredoxin domain containing 11. (956 aa)
PIK3R2Uncharacterized protein. (724 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
GRASPGeneral receptor for phosphoinositides 1 associated scaffold protein. (394 aa)
PID1Phosphotyrosine interaction domain containing 1. (217 aa)
AGR2Anterior gradient 2, protein disulphide isomerase family member. (175 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
EPHA3EPH receptor A3. (984 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (489 aa)
BBC3Uncharacterized protein. (193 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
ABI3ABI family member 3. (359 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
GPC2Glypican 2; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (578 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (636 aa)
STAC3SH3 and cysteine rich domain 3. (362 aa)
CIB1Calcium and integrin binding 1. (191 aa)
CD81Tetraspanin. (236 aa)
RHOGRas homolog family member G. (191 aa)
VIL1Villin 1. (827 aa)
HECTD1HECT domain E3 ubiquitin protein ligase 1. (2610 aa)
STX7Syntaxin 7; Belongs to the syntaxin family. (261 aa)
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2350 aa)
TGFB1Transforming growth factor beta 1. (443 aa)
STX3Syntaxin 3; Belongs to the syntaxin family. (359 aa)
AKT2AKT serine/threonine kinase 2. (603 aa)
SHISA7Shisa family member 7. (612 aa)
DAB2DAB adaptor protein 2. (779 aa)
GOPCPDZ domain-containing protein. (483 aa)
EGFRReceptor protein-tyrosine kinase. (1209 aa)
STACSH3 and cysteine rich domain. (403 aa)
ZDHHC7Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (308 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
CEMIPCell migration inducing hyaluronidase 1. (1416 aa)
MESDMesoderm development LRP chaperone. (276 aa)
RANGRFRAN guanine nucleotide release factor. (186 aa)
A0A4W2C5I5Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (104 aa)
STX8Syntaxin 8. (369 aa)
PICALMPhosphatidylinositol binding clathrin assembly protein. (686 aa)
MYO1CMyosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1098 aa)
MIEF2Mitochondrial elongation factor 2. (454 aa)
STAC2SH3 and cysteine rich domain 2. (438 aa)
A0A4W2BZP2Uncharacterized protein. (115 aa)
ARAndrogen receptor. (889 aa)
SLC7A11Solute carrier family 7 member 11. (503 aa)
NHLRC1NHL repeat containing E3 ubiquitin protein ligase 1. (394 aa)
APPL1Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (708 aa)
DAG1Dystroglycan 1. (1096 aa)
LZTFL1Leucine zipper transcription factor like 1. (344 aa)
CSRP3Cysteine and glycine rich protein 3. (200 aa)
CLN3Battenin. (460 aa)
A0A4W2BND6IlGF domain-containing protein; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (100 aa)
EZREzrin. (638 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa)
CRIPTCXXC repeat containing interactor of PDZ3 domain. (101 aa)
MMP14Matrix metallopeptidase 14. (582 aa)
FRRS1LFerric chelate reductase 1 like. (344 aa)
NUMBNUMB endocytic adaptor protein. (642 aa)
PDZK1PDZ domain containing 1. (732 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
DMTNDematin actin binding protein. (467 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
LDLRAP1Low density lipoprotein receptor adaptor protein 1. (310 aa)
SQSTM1Sequestosome 1. (529 aa)
TNFAIP6TNF alpha induced protein 6. (298 aa)
MRAPUncharacterized protein. (194 aa)
GSNGelsolin. (846 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (747 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (449 aa)
R3HDM1R3H domain containing 1. (1118 aa)
DPP10Dipeptidyl peptidase like 10; Belongs to the peptidase S9B family. (796 aa)
TCAF1TRPM8 channel associated factor 1. (921 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1682 aa)
SLC51BSolute carrier family 51 beta subunit. (130 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
ERBB2Erb-b2 receptor tyrosine kinase 2. (1710 aa)
ACTBActin beta. (375 aa)
ATP2C1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (974 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1065 aa)
A0A4W2E2B7Uncharacterized protein. (192 aa)
RHOQRas homolog family member Q. (209 aa)
DLG2Discs large MAGUK scaffold protein 2. (1009 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (990 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1207 aa)
RER1Retention in endoplasmic reticulum sorting receptor 1. (291 aa)
VPS4AUncharacterized protein; Belongs to the AAA ATPase family. (437 aa)
LGALS3Galectin. (265 aa)
CLIP3CAP-Gly domain containing linker protein 3. (547 aa)
A0A4W2E9C2Uncharacterized protein. (461 aa)
TMBIM1Transmembrane BAX inhibitor motif containing 1; Belongs to the BI1 family. (308 aa)
RAMP3Receptor activity modifying protein 3. (150 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (321 aa)
A0A4W2EBL9Uncharacterized protein. (1267 aa)
PKDCCProtein kinase domain containing, cytoplasmic. (493 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
WNK3WNK lysine deficient protein kinase 3. (1789 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (333 aa)
ARHGAP44Rho GTPase activating protein 44. (804 aa)
R3HDM2Uncharacterized protein. (1023 aa)
GPC5Glypican 5; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (571 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (148 aa)
FYNTyrosine-protein kinase. (537 aa)
CHP1Calcineurin like EF-hand protein 1. (195 aa)
NKD2NKD inhibitor of WNT signaling pathway 2. (483 aa)
A0A4W2ESW9Uncharacterized protein. (122 aa)
GPC6Glypican 6; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (555 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (460 aa)
CNSTConsortin, connexin sorting protein. (720 aa)
EPM2AEPM2A glucan phosphatase, laforin. (331 aa)
ARHGEF16Rho guanine nucleotide exchange factor 16. (708 aa)
CRKLCRK like proto-oncogene, adaptor protein. (302 aa)
LRP1LDL receptor related protein 1. (4544 aa)
MFFMitochondrial fission factor. (409 aa)
ACSL3Acyl-CoA synthetase long chain family member 3. (720 aa)
ZDHHC5Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (714 aa)
LRP4LDL receptor related protein 4. (1905 aa)
MRAP2Melanocortin 2 receptor accessory protein 2. (204 aa)
MIEF1Mitochondrial elongation factor 1. (463 aa)
ANXA13Annexin. (365 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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