STRINGSTRING
DLG1 DLG1 CRADD CRADD EZH2 EZH2 CASP2 CASP2 PKD2 PKD2 ZNF655 ZNF655 CDK2AP2 CDK2AP2 CCL2 CCL2 A0A4W2DWY9 A0A4W2DWY9 DLG2 DLG2 PML PML CCND1 CCND1 CDKN1A CDKN1A BRD7 BRD7 CTDSP2 CTDSP2 RPS27L RPS27L E2F7 E2F7 GPNMB GPNMB A0A4W2EVL2 A0A4W2EVL2 WAC WAC TP53 TP53 RB1 RB1 NACC2 NACC2 DACT1 DACT1 KANK2 KANK2 CTDSPL CTDSPL RBL1 RBL1 PLK3 PLK3 GML GML FBXO7 FBXO7 A0A4W2EYN7 A0A4W2EYN7 PIDD1 PIDD1 CRLF3 CRLF3 DCUN1D3 DCUN1D3 BCL2 BCL2 RFWD3 RFWD3 A0A4W2C0C3 A0A4W2C0C3 JADE1 JADE1 A0A4W2C3D5 A0A4W2C3D5 FBXO31 FBXO31 APC APC RBL2 RBL2 A0A4W2CC63 A0A4W2CC63 A0A4W2CDI7 A0A4W2CDI7 PRKDC PRKDC CTDSP1 CTDSP1 INHBA INHBA SDE2 SDE2 CDC73 CDC73
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa)
CRADDCASP2 and RIPK1 domain containing adaptor with death domain. (287 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (779 aa)
CASP2Caspase 2; Belongs to the peptidase C14A family. (452 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (1071 aa)
ZNF655Zinc finger protein 655. (543 aa)
CDK2AP2Cyclin-dependent kinase 2-associated protein; Belongs to the CDK2AP family. (127 aa)
CCL2C-C motif chemokine. (99 aa)
A0A4W2DWY9UPAR/Ly6 domain-containing protein. (155 aa)
DLG2Discs large MAGUK scaffold protein 2. (1009 aa)
PMLPromyelocytic leukemia. (871 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (428 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (161 aa)
BRD7Bromodomain containing 7. (853 aa)
CTDSP2CTD small phosphatase 2. (271 aa)
RPS27L40S ribosomal protein S27. (102 aa)
E2F7E2F transcription factor 7. (912 aa)
GPNMBGlycoprotein nmb. (555 aa)
A0A4W2EVL2Serine/threonine-protein kinase PLK. (548 aa)
WACWW domain containing adaptor with coiled-coil. (646 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (499 aa)
RB1RB transcriptional corepressor 1. (928 aa)
NACC2NACC family member 2. (585 aa)
DACT1Dishevelled binding antagonist of beta catenin 1. (837 aa)
KANK2KN motif and ankyrin repeat domains 2. (858 aa)
CTDSPLCTD small phosphatase like. (276 aa)
RBL1RB transcriptional corepressor like 1. (1068 aa)
PLK3Serine/threonine-protein kinase PLK. (647 aa)
GMLUPAR/Ly6 domain-containing protein. (155 aa)
FBXO7F-box protein 7. (522 aa)
A0A4W2EYN7SEA domain-containing protein. (663 aa)
PIDD1P53-induced death domain protein 1. (946 aa)
CRLF3Fibronectin type-III domain-containing protein. (441 aa)
DCUN1D3DCN1-like protein. (304 aa)
BCL2BCL2 apoptosis regulator. (229 aa)
RFWD3Ring finger and WD repeat domain 3. (790 aa)
A0A4W2C0C340S ribosomal protein S27. (95 aa)
JADE1Jade family PHD finger 1. (872 aa)
A0A4W2C3D5Uncharacterized protein. (223 aa)
FBXO31F-box protein 31. (558 aa)
APCAPC regulator of WNT signaling pathway. (2912 aa)
RBL2RB transcriptional corepressor like 2. (1140 aa)
A0A4W2CC63Fibronectin type-III domain-containing protein. (399 aa)
A0A4W2CDI7Uncharacterized protein. (148 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4122 aa)
CTDSP1CTD small phosphatase 1. (283 aa)
INHBAInhibin subunit beta A. (425 aa)
SDE2SDE2 telomere maintenance homolog. (453 aa)
CDC73Cell division cycle 73. (531 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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