STRINGSTRING
FURIN FURIN AP1S1 AP1S1 LOC113884940 LOC113884940 A0A4W2BXG6 A0A4W2BXG6 MYO6 MYO6 A0A4W2CEA2 A0A4W2CEA2 STON1 STON1 AP2S1 AP2S1 AP1S3 AP1S3 VLDLR VLDLR ITSN2 ITSN2 REPS1 REPS1 SLC18A3 SLC18A3 SH3BP4 SH3BP4 EPS15 EPS15 A0A4W2DEY8 A0A4W2DEY8 FCHO1 FCHO1 DNM1L DNM1L DNM2 DNM2 AP2A2 AP2A2 LRP2 LRP2 AP2B1 AP2B1 SPHK1 SPHK1 CDCP2 CDCP2 RAB35 RAB35 APP APP A0A4W2E161 A0A4W2E161 ADCY8 ADCY8 A0A4W2E3N8 A0A4W2E3N8 ATAT1 ATAT1 A0A4W2E5Z3 A0A4W2E5Z3 AP2A1 AP2A1 ARRB1 ARRB1 A0A4W2ERJ0 A0A4W2ERJ0 AP2M1 AP2M1 ACKR3 ACKR3 LOC113904454 LOC113904454 ITSN1 ITSN1 EPS15L1 EPS15L1 SGIP1 SGIP1 FCHO2 FCHO2 PCSK4 PCSK4 A0A4W2FQ17 A0A4W2FQ17
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (797 aa)
AP1S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
LOC113884940Uncharacterized protein. (2120 aa)
A0A4W2BXG6MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (341 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1289 aa)
A0A4W2CEA2Alpha-carbonic anhydrase domain-containing protein; Belongs to the alpha-carbonic anhydrase family. (125 aa)
STON1Uncharacterized protein; Belongs to the Stoned B family. (732 aa)
AP2S1Adaptor related protein complex 2 subunit sigma 1. (231 aa)
AP1S3Adaptor related protein complex 1 subunit sigma 3. (251 aa)
VLDLRVery low density lipoprotein receptor. (1190 aa)
ITSN2Intersectin 2. (1677 aa)
REPS1RALBP1 associated Eps domain containing 1. (795 aa)
SLC18A3Solute carrier family 18 member A3. (524 aa)
SH3BP4SH3 domain binding protein 4. (963 aa)
EPS15Epidermal growth factor receptor pathway substrate 15; Belongs to the calreticulin family. (994 aa)
A0A4W2DEY8Clat_adaptor_s domain-containing protein. (87 aa)
FCHO1FCH domain only 1. (887 aa)
DNM1LDynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (749 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (880 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (935 aa)
LRP2LDL receptor related protein 2. (4647 aa)
AP2B1Uncharacterized protein. (995 aa)
SPHK1Sphingosine kinase 1. (489 aa)
CDCP2CUB domain containing protein 2. (540 aa)
RAB35RAB35, member RAS oncogene family. (263 aa)
APPAmyloid beta precursor protein. (770 aa)
A0A4W2E161Alpha-carbonic anhydrase domain-containing protein; Belongs to the alpha-carbonic anhydrase family. (195 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1253 aa)
A0A4W2E3N8B2-adapt-app_C domain-containing protein. (266 aa)
ATAT1Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] (409 aa)
A0A4W2E5Z3Uncharacterized protein. (338 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (978 aa)
ARRB1Arrestin beta 1. (513 aa)
A0A4W2ERJ0EH domain-containing protein. (105 aa)
AP2M1MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (435 aa)
ACKR3Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (362 aa)
LOC113904454Alpha-carbonic anhydrase domain-containing protein; Belongs to the alpha-carbonic anhydrase family. (261 aa)
ITSN1Intersectin 1. (1721 aa)
EPS15L1Epidermal growth factor receptor pathway substrate 15 like 1. (939 aa)
SGIP1SH3 domain GRB2 like endophilin interacting protein 1. (825 aa)
FCHO2FCH domain only 2. (811 aa)
PCSK4Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (752 aa)
A0A4W2FQ17Uncharacterized protein. (249 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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