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CREB3 CREB3 SARM1 SARM1 GIT1 GIT1 SEZ6 SEZ6 GRIP2 GRIP2 CNIH2 CNIH2 SLC3A2 SLC3A2 FLRT1 FLRT1 LOC113884940 LOC113884940 ATOH7 ATOH7 NR1D1 NR1D1 BAG2 BAG2 AMIGO3 AMIGO3 OPHN1 OPHN1 MAPK8IP3 MAPK8IP3 INPP5A INPP5A NRGN NRGN CPLX2 CPLX2 CPNE7 CPNE7 NOS1 NOS1 BRINP2 BRINP2 GRID2IP GRID2IP MAP1A MAP1A TRPV1 TRPV1 GRIA2 GRIA2 CALB1 CALB1 TANC2 TANC2 CALB2 CALB2 RUNDC1 RUNDC1 NTF4 NTF4 RTN4RL2 RTN4RL2 MAP2 MAP2 ALS2 ALS2 LRP4 LRP4 NTF3 NTF3 BCR BCR RGS8 RGS8 PTPRN PTPRN SRGAP1 SRGAP1 KCND2 KCND2 DNER DNER ABHD13 ABHD13 OPRM1 OPRM1 NECTIN3 NECTIN3 CD200 CD200 TRIM9 TRIM9 CAPN2 CAPN2 A0A4W2D0D8 A0A4W2D0D8 PTRHD1 PTRHD1 ZNF385A ZNF385A CRIPT CRIPT APOD APOD A0A4W2D1D1 A0A4W2D1D1 SLC4A8 SLC4A8 NSG1 NSG1 PALMD PALMD MAPK8 MAPK8 AMIGO1 AMIGO1 GRIN3A GRIN3A SGCE SGCE RUFY3 RUFY3 DNM3 DNM3 CRHBP CRHBP SLC4A10 SLC4A10 KCNC2 KCNC2 KIF1A KIF1A UBR3 UBR3 PPP1R9A PPP1R9A MME MME DHX36 DHX36 GLRA1 GLRA1 DIP2B DIP2B MYO1D MYO1D KCND3 KCND3 RBM3 RBM3 VSTM5 VSTM5 ELOVL5 ELOVL5 LRP2 LRP2 NCDN NCDN PTPRO PTPRO NPAS4 NPAS4 GPER1 GPER1 GPM6A GPM6A NSG2 NSG2 TMEM185B TMEM185B BRINP3 BRINP3 ADCY8 ADCY8 HPN HPN SIRT2 SIRT2 URAD URAD ABR ABR KIRREL3 KIRREL3 NF1 NF1 CTTNBP2 CTTNBP2 SYNDIG1 SYNDIG1 EPHA4 EPHA4 PRKCG PRKCG STUM STUM CNIH3 CNIH3 FARP1 FARP1 A0A4W2EE95 A0A4W2EE95 FRMPD1 FRMPD1 ARHGAP44 ARHGAP44 A0A4W2EG78 A0A4W2EG78 ARHGEF15 ARHGEF15 DOCK10 DOCK10 ADCY3 ADCY3 KPNA1 KPNA1 A0A4W2ERB4 A0A4W2ERB4 PSEN1 PSEN1 PDLIM4 PDLIM4 SIPA1L1 SIPA1L1 SST SST KCNC4 KCNC4 SLC12A2 SLC12A2 GPHN GPHN FXR1 FXR1 ZNF804A ZNF804A OTP OTP RGS14 RGS14 A0A4W2EUV9 A0A4W2EUV9 GIGYF2 GIGYF2 EPS8 EPS8 A0A4W2EZ36 A0A4W2EZ36 TMEM108 TMEM108 CPNE4 CPNE4 SYNPO SYNPO PVALB PVALB CDX1 CDX1 FAM151B FAM151B ABI3BP ABI3BP RGS12 RGS12 RAPGEF2 RAPGEF2 KIF5A KIF5A NEURL1 NEURL1 ARHGAP42 ARHGAP42 LOC113878920 LOC113878920 MAPK10 MAPK10 DRD1 DRD1 KCNB2 KCNB2 SLC38A7 SLC38A7 CADM2 CADM2 TBR1 TBR1 PDE4B PDE4B DBN1 DBN1 TMEM60 TMEM60 TAOK2 TAOK2 SLC6A3 SLC6A3 LZTS1 LZTS1 SEPTIN14 SEPTIN14 A0A4W2HAI6 A0A4W2HAI6 TGFB2 TGFB2 CCIN CCIN SRGAP2 SRGAP2 KCNC3 KCNC3 ATP6AP2 ATP6AP2 ARFGEF2 ARFGEF2 UNC5A UNC5A FXR2 FXR2 CX3CR1 CX3CR1 NSMF NSMF ZPR1 ZPR1 CPNE6 CPNE6 PSEN2 PSEN2 PPP1R1B PPP1R1B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CREB3cAMP responsive element binding protein 3. (365 aa)
SARM1Sterile alpha and TIR motif containing 1. (728 aa)
GIT1GIT ArfGAP 1. (770 aa)
SEZ6Seizure related 6 homolog. (983 aa)
GRIP2Glutamate receptor interacting protein 2. (1045 aa)
CNIH2Cornichon family AMPA receptor auxiliary protein 2. (160 aa)
SLC3A2Solute carrier family 3 member 2. (572 aa)
FLRT1Fibronectin leucine rich transmembrane protein 1. (677 aa)
LOC113884940Uncharacterized protein. (2120 aa)
ATOH7Atonal bHLH transcription factor 7. (152 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (613 aa)
BAG2BCL2 associated athanogene 2. (211 aa)
AMIGO3Adhesion molecule with Ig like domain 3. (519 aa)
OPHN1Oligophrenin 1. (685 aa)
MAPK8IP3Mitogen-activated protein kinase 8 interacting protein 3. (1342 aa)
INPP5AInositol polyphosphate-5-phosphatase A. (412 aa)
NRGNNeurogranin. (78 aa)
CPLX2Complexin 2. (217 aa)
CPNE7Copine 7. (549 aa)
NOS1Nitric oxide synthase 1. (1468 aa)
BRINP2BMP/retinoic acid inducible neural specific 2. (784 aa)
GRID2IPGrid2 interacting protein. (1215 aa)
MAP1AMicrotubule associated protein 1A. (3122 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (837 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
CALB1Calbindin 1. (236 aa)
TANC2Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2. (2063 aa)
CALB2Calbindin 2. (279 aa)
RUNDC1RUN domain containing 1. (613 aa)
NTF4Neurotrophin 4; Belongs to the NGF-beta family. (306 aa)
RTN4RL2Reticulon 4 receptor like 2. (461 aa)
MAP2Microtubule-associated protein. (1836 aa)
ALS2Alsin Rho guanine nucleotide exchange factor ALS2. (1656 aa)
LRP4LDL receptor related protein 4. (1905 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (297 aa)
BCRBCR activator of RhoGEF and GTPase. (1283 aa)
RGS8Regulator of G protein signaling 8. (180 aa)
PTPRNProtein tyrosine phosphatase receptor type N. (979 aa)
SRGAP1SLIT-ROBO Rho GTPase activating protein 1. (1085 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (630 aa)
DNERDelta/notch like EGF repeat containing. (1010 aa)
ABHD13Abhydrolase domain containing 13. (375 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (419 aa)
NECTIN3Nectin cell adhesion molecule 3. (549 aa)
CD200CD200 molecule. (301 aa)
TRIM9Tripartite motif containing 9. (795 aa)
CAPN2Calpain 2; Belongs to the peptidase C2 family. (700 aa)
A0A4W2D0D8XRCC1_N domain-containing protein. (405 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
ZNF385AZinc finger protein 385A. (393 aa)
CRIPTCXXC repeat containing interactor of PDZ3 domain. (101 aa)
APODApolipoprotein D. (217 aa)
A0A4W2D1D1Uncharacterized protein. (174 aa)
SLC4A8Anion exchange protein. (1092 aa)
NSG1Neuronal vesicle trafficking associated 1. (218 aa)
PALMDPalmdelphin. (550 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
AMIGO1Adhesion molecule with Ig like domain 1. (493 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1114 aa)
SGCESarcoglycan epsilon. (496 aa)
RUFY3RUN and FYVE domain containing 3. (640 aa)
DNM3Dynamin 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (869 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (324 aa)
SLC4A10Anion exchange protein. (1147 aa)
KCNC2Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (629 aa)
KIF1AKinesin family member 1A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1795 aa)
UBR3E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1888 aa)
PPP1R9AProtein phosphatase 1 regulatory subunit 9A. (1361 aa)
MMEMembrane metalloendopeptidase. (775 aa)
DHX36DEAH-box helicase 36. (1010 aa)
GLRA1Glycine receptor alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (457 aa)
DIP2BDisco interacting protein 2 homolog B. (1652 aa)
MYO1DMyosin ID; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1006 aa)
KCND3Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (655 aa)
RBM3RNA binding motif protein 3. (160 aa)
VSTM5V-set and transmembrane domain containing 5. (200 aa)
ELOVL5Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (299 aa)
LRP2LDL receptor related protein 2. (4647 aa)
NCDNNeurochondrin. (729 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1216 aa)
NPAS4Neuronal PAS domain protein 4. (798 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
GPM6AGlycoprotein M6A. (317 aa)
NSG2Neuronal vesicle trafficking associated 2. (171 aa)
TMEM185BTransmembrane protein 185B. (350 aa)
BRINP3BMP/retinoic acid inducible neural specific 3. (766 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1253 aa)
HPNHepsin; Belongs to the peptidase S1 family. (454 aa)
SIRT2Sirtuin 2. (457 aa)
URADOHCU_decarbox domain-containing protein. (170 aa)
ABRABR activator of RhoGEF and GTPase. (1349 aa)
KIRREL3Kirre like nephrin family adhesion molecule 3. (778 aa)
NF1Neurofibromin 1. (3024 aa)
CTTNBP2Cortactin binding protein 2. (1664 aa)
SYNDIG1Synapse differentiation inducing 1. (264 aa)
EPHA4EPH receptor A4. (949 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (771 aa)
STUMUncharacterized protein. (436 aa)
CNIH3Cornichon family AMPA receptor auxiliary protein 3. (190 aa)
FARP1FERM, ARH/RhoGEF and pleckstrin domain protein 1. (1046 aa)
A0A4W2EE95Ion_trans domain-containing protein. (432 aa)
FRMPD1FERM and PDZ domain containing 1. (1587 aa)
ARHGAP44Rho GTPase activating protein 44. (804 aa)
A0A4W2EG78Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (171 aa)
ARHGEF15Rho guanine nucleotide exchange factor 15. (847 aa)
DOCK10Dedicator of cytokinesis 10; Belongs to the DOCK family. (2199 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1146 aa)
KPNA1Karyopherin subunit alpha 1. (954 aa)
A0A4W2ERB4Uncharacterized protein. (242 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (478 aa)
PDLIM4PDZ and LIM domain 4. (311 aa)
SIPA1L1Signal induced proliferation associated 1 like 1. (1805 aa)
SSTSomatostatin. (116 aa)
KCNC4Potassium voltage-gated channel subfamily C member 4; Belongs to the potassium channel family. (659 aa)
SLC12A2Solute carrier family 12 member 2. (1204 aa)
GPHNGephyrin. (839 aa)
FXR1FMR1 autosomal homolog 1. (648 aa)
ZNF804AZinc finger protein 804A. (1208 aa)
OTPOrthopedia homeobox. (415 aa)
RGS14Regulator of G protein signaling 14. (565 aa)
A0A4W2EUV9Ephrin RBD domain-containing protein; Belongs to the ephrin family. (449 aa)
GIGYF2GRB10 interacting GYF protein 2. (1291 aa)
EPS8Epidermal growth factor receptor pathway substrate 8. (836 aa)
A0A4W2EZ36Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (330 aa)
TMEM108Transmembrane protein 108. (642 aa)
CPNE4Copine 4. (592 aa)
SYNPOSynaptopodin. (1131 aa)
PVALBParvalbumin; Belongs to the parvalbumin family. (142 aa)
CDX1Caudal type homeobox 1. (265 aa)
FAM151BFamily with sequence similarity 151 member B. (304 aa)
ABI3BPABI family member 3 binding protein. (872 aa)
RGS12Regulator of G protein signaling 12. (1397 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1689 aa)
KIF5AKinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1032 aa)
NEURL1Neuralized E3 ubiquitin protein ligase 1. (574 aa)
ARHGAP42Rho GTPase activating protein 42. (874 aa)
LOC113878920Tudor domain-containing protein. (289 aa)
MAPK10Mitogen-activated protein kinase. (425 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
KCNB2Potassium voltage-gated channel subfamily B member 2; Belongs to the potassium channel family. (911 aa)
SLC38A7Solute carrier family 38 member 7. (463 aa)
CADM2Cell adhesion molecule 2. (437 aa)
TBR1T-box brain transcription factor 1. (682 aa)
PDE4BPhosphodiesterase. (736 aa)
DBN1Drebrin 1. (726 aa)
TMEM60Transmembrane protein 60. (133 aa)
TAOK2TAO kinase 2. (1125 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (617 aa)
LZTS1Leucine zipper tumor suppressor 1. (595 aa)
SEPTIN14Septin 14; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (432 aa)
A0A4W2HAI6Uncharacterized protein. (68 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
CCINCalicin. (588 aa)
SRGAP2Uncharacterized protein. (1084 aa)
KCNC3Potassium voltage-gated channel subfamily C member 3; Belongs to the potassium channel family. (734 aa)
ATP6AP2Uncharacterized protein. (377 aa)
ARFGEF2ADP ribosylation factor guanine nucleotide exchange factor 2. (1779 aa)
UNC5AUnc-5 netrin receptor A. (902 aa)
FXR2FMR1 autosomal homolog 2. (673 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (358 aa)
NSMFNMDA receptor synaptonuclear signaling and neuronal migration factor. (532 aa)
ZPR1ZPR1 zinc finger. (459 aa)
CPNE6Copine 6. (557 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (449 aa)
PPP1R1BProtein phosphatase 1 regulatory inhibitor subunit 1B. (202 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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