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CNN1 CNN1 CNN2 CNN2 PFN4 PFN4 PFN1 PFN1 PFN3 PFN3 MYO5A MYO5A CAPZA1 CAPZA1 CFL1 CFL1 MYH11 MYH11 PFN2 PFN2 CAPZA3 CAPZA3 VASP VASP LOC113876999 LOC113876999 FSCN1 FSCN1 FSCN2 FSCN2 MYO1A MYO1A MYH14 MYH14 PLS1 PLS1 MYO10 MYO10 MYO7B MYO7B MYH15 MYH15 MYO1B MYO1B MYH9 MYH9 XIRP2 XIRP2 A0A4W2EVV4 A0A4W2EVV4 SHROOM3 SHROOM3 ACTN1 ACTN1 MYH6 MYH6 SYNE2 SYNE2 CNN3 CNN3 MYH7B MYH7B UTRN UTRN MYO16 MYO16 ARPC3 ARPC3 MYO5C MYO5C ARPC2 ARPC2 A0A4W2EFN2 A0A4W2EFN2 PLEC PLEC CAPZA2 CAPZA2 A0A4W2EBV7 A0A4W2EBV7 CFL2 CFL2 ACTN4 ACTN4 A0A4W2E1I0 A0A4W2E1I0 ARPC1B ARPC1B FLNB FLNB PHACTR1 PHACTR1 XIRP1 XIRP1 SPTBN2 SPTBN2 MYO5B MYO5B MYO1C MYO1C MYH2 MYH2 MYH13 MYH13 MYH10 MYH10 MYO18B MYO18B MYO1H MYO1H ARPC4 ARPC4 MYH3 MYH3 CLMN CLMN LCP1 LCP1 MYH8 MYH8 TMSB4X TMSB4X ACTN3 ACTN3 TMSB10 TMSB10 MYO6 MYO6 MYO7A MYO7A SPTBN4 SPTBN4 SPTBN1 SPTBN1 ACTR2 ACTR2 DST DST ACTN2 ACTN2 MYO19 MYO19 MYO1D MYO1D MYO18A MYO18A A0A4W2DHA5 A0A4W2DHA5 CAPZB CAPZB SHROOM1 SHROOM1 MACF1 MACF1 A0A4W2DD42 A0A4W2DD42 MYO9B MYO9B SPTB SPTB MYO3B MYO3B MYO9A MYO9A MYO3A MYO3A DSTN DSTN MYO1G MYO1G MYO1E MYO1E FSCN3 FSCN3 SYNE1 SYNE1 FLNC FLNC PHACTR2 PHACTR2 PHACTR4 PHACTR4 A0A4W2CZR5 A0A4W2CZR5 MYO1F MYO1F
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CNN1Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (297 aa)
CNN2Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (334 aa)
PFN4Profilin; Belongs to the profilin family. (129 aa)
PFN1Profilin; Belongs to the profilin family. (140 aa)
PFN3Profilin; Belongs to the profilin family. (137 aa)
MYO5AMyosin VA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1877 aa)
CAPZA1F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (286 aa)
CFL1Cofilin 1; Belongs to the actin-binding proteins ADF family. (166 aa)
MYH11Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1979 aa)
PFN2Profilin; Belongs to the profilin family. (142 aa)
CAPZA3F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (299 aa)
VASPVasodilator stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (383 aa)
LOC113876999Myosin heavy chain 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1938 aa)
FSCN1Fascin. (493 aa)
FSCN2Fascin. (492 aa)
MYO1AMyosin IA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1043 aa)
MYH14Myosin heavy chain 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2040 aa)
PLS1Plastin 1. (630 aa)
MYO10Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2052 aa)
MYO7BMyosin VIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2140 aa)
MYH15Myosin heavy chain 15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1964 aa)
MYO1BMyosin IB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1136 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1986 aa)
XIRP2Xin actin binding repeat containing 2. (3532 aa)
A0A4W2EVV4Profilin; Belongs to the profilin family. (87 aa)
SHROOM3Shroom family member 3. (1988 aa)
ACTN1Actinin alpha 1. (962 aa)
MYH6Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1967 aa)
SYNE2Spectrin repeat containing nuclear envelope protein 2. (6919 aa)
CNN3Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (329 aa)
MYH7BMyosin heavy chain 7B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1941 aa)
UTRNUtrophin. (3432 aa)
MYO16Myosin XVI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1713 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (190 aa)
MYO5CMyosin VC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1742 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (300 aa)
A0A4W2EFN2Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1409 aa)
PLECPlectin. (4671 aa)
CAPZA2F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (286 aa)
A0A4W2EBV7Phosphatase and actin regulator. (560 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
ACTN4Actinin alpha 4. (933 aa)
A0A4W2E1I0Phosphatase and actin regulator. (201 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (372 aa)
FLNBFilamin B. (2771 aa)
PHACTR1Phosphatase and actin regulator. (659 aa)
XIRP1Xin actin binding repeat containing 1. (1820 aa)
SPTBN2Spectrin beta chain; Belongs to the spectrin family. (2531 aa)
MYO5BUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1846 aa)
MYO1CMyosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1098 aa)
MYH2Myosin heavy chain 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1965 aa)
MYH13Myosin heavy chain 13; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1938 aa)
MYH10Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2007 aa)
MYO18BMyosin XVIIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2523 aa)
MYO1HMyosin IH; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1038 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (168 aa)
MYH3Myosin heavy chain 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1940 aa)
CLMNCalmin. (1058 aa)
LCP1Lymphocyte cytosolic protein 1. (643 aa)
MYH8Myosin heavy chain 8; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
TMSB4XThymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (44 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (901 aa)
TMSB10Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (45 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1289 aa)
MYO7AMyosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2116 aa)
SPTBN4Spectrin beta, non-erythrocytic 4. (2615 aa)
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2350 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (406 aa)
DSTDystonin. (5537 aa)
ACTN2Actinin alpha 2. (894 aa)
MYO19Myosin XIX; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (947 aa)
MYO1DMyosin ID; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1006 aa)
MYO18AMyosin XVIIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2055 aa)
A0A4W2DHA5Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (159 aa)
CAPZBF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (306 aa)
SHROOM1Shroom family member 1. (843 aa)
MACF1Microtubule actin crosslinking factor 1. (7557 aa)
A0A4W2DD42Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (283 aa)
MYO9BMyosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2150 aa)
SPTBSpectrin beta chain; Belongs to the spectrin family. (2331 aa)
MYO3BMyosin IIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1340 aa)
MYO9AMyosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2611 aa)
MYO3AMyosin IIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1623 aa)
DSTNDestrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family. (165 aa)
MYO1GMyosin IG; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (995 aa)
MYO1EMyosin IE; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1108 aa)
FSCN3Fascin. (497 aa)
SYNE1Spectrin repeat containing nuclear envelope protein 1. (8798 aa)
FLNCFilamin C. (2736 aa)
PHACTR2Phosphatase and actin regulator. (638 aa)
PHACTR4Phosphatase and actin regulator. (712 aa)
A0A4W2CZR5Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (406 aa)
MYO1FMyosin IF; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1098 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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