STRINGSTRING
SPATA5L1 SPATA5L1 POLD1 POLD1 A0A4W2DPH7 A0A4W2DPH7 POLI POLI RFC2 RFC2 RCBTB1 RCBTB1 RPA1 RPA1 RCHY1 RCHY1 POLD2 POLD2 POLE3 POLE3 KXD1 KXD1 RFC1 RFC1 RPA3 RPA3 A0A4W2EP37 A0A4W2EP37 UBE2L6 UBE2L6 REV3L REV3L TRIM47 TRIM47 POLE4 POLE4 ISG15 ISG15 VCP VCP POLD3 POLD3 MAD2L2 MAD2L2 UFD1 UFD1 RCBTB2 RCBTB2 A0A4W2E0Q1 A0A4W2E0Q1 A0A4W2C218 A0A4W2C218 UBA7 UBA7 POLD4 POLD4 RFC3 RFC3 SPATA5 SPATA5 USP31 USP31 ATAD5 ATAD5 MEIOB MEIOB POLE2 POLE2 POLE POLE RPS27A RPS27A A0A4W2C7C3 A0A4W2C7C3 USP43 USP43 POLK POLK POLH POLH SPRTN SPRTN TRIM25 TRIM25 A0A4W2DY12 A0A4W2DY12 RFC5 RFC5 PCNA PCNA RFC4 RFC4 A0A4W2D3W4 A0A4W2D3W4 PCLAF PCLAF REV1 REV1 UBC UBC RPA2 RPA2 USP10 USP10 TRIM65 TRIM65
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SPATA5L1Spermatogenesis associated 5 like 1. (767 aa)
POLD1DNA polymerase. (1106 aa)
A0A4W2DPH7Ubiquitin-like domain-containing protein. (120 aa)
POLIDNA polymerase iota. (760 aa)
RFC2Replication factor C subunit 2. (352 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
RCHY1Ring finger and CHY zinc finger domain containing 1. (261 aa)
POLD2DNA polymerase delta 2, accessory subunit. (580 aa)
POLE3DNA polymerase epsilon 3, accessory subunit. (147 aa)
KXD1KxDL domain-containing protein. (212 aa)
RFC1Replication factor C subunit 1. (1146 aa)
RPA3Replication protein A3. (121 aa)
A0A4W2EP37PAF domain-containing protein. (92 aa)
UBE2L6Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
REV3LREV3 like, DNA directed polymerase zeta catalytic subunit. (3133 aa)
TRIM47Tripartite motif containing 47. (649 aa)
POLE4DNA polymerase epsilon 4, accessory subunit. (120 aa)
ISG15ISG15 ubiquitin like modifier. (154 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (816 aa)
POLD3Uncharacterized protein. (425 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (211 aa)
UFD1Ubiquitin recognition factor in ER associated degradation 1. (307 aa)
RCBTB2RCC1 and BTB domain containing protein 2. (554 aa)
A0A4W2E0Q1Ubiquitin-like domain-containing protein. (77 aa)
A0A4W2C218Uncharacterized protein. (627 aa)
UBA7Ubiquitin like modifier activating enzyme 7. (1001 aa)
POLD4Uncharacterized protein. (315 aa)
RFC3Replication factor C subunit 3. (356 aa)
SPATA5Spermatogenesis associated 5. (868 aa)
USP31Ubiquitin specific peptidase 31; Belongs to the peptidase C19 family. (1347 aa)
ATAD5ATPase family AAA domain containing 5. (1893 aa)
MEIOBMeiosis specific with OB-fold. (472 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2289 aa)
RPS27AUbiquitin-like domain-containing protein. (194 aa)
A0A4W2C7C3KxDL domain-containing protein. (179 aa)
USP43Ubiquitin specific peptidase 43; Belongs to the peptidase C19 family. (1138 aa)
POLKDNA polymerase kappa. (911 aa)
POLHDNA polymerase eta. (711 aa)
SPRTNSprT-like N-terminal domain. (487 aa)
TRIM25Tripartite motif containing 25. (631 aa)
A0A4W2DY12RPA_C domain-containing protein. (270 aa)
RFC5Replication factor C subunit 5. (527 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (326 aa)
RFC4Replication factor C subunit 4. (364 aa)
A0A4W2D3W4Ubiquitin-like domain-containing protein. (160 aa)
PCLAFPAF domain-containing protein. (114 aa)
REV1DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1253 aa)
UBCUbiquitin C. (1146 aa)
RPA2RPA_C domain-containing protein. (270 aa)
USP10Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (800 aa)
TRIM65Tripartite motif containing 65. (548 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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