39 items (Bos indicus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A4W2DPH7	Ubiquitin-like domain-containing protein. (120 aa)
	ATAD5	ATPase family AAA domain containing 5. (1893 aa)
	RAD18	RAD18 E3 ubiquitin protein ligase. (501 aa)
	USP1	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (783 aa)
	MEIOB	Meiosis specific with OB-fold. (472 aa)
	POLE2	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (326 aa)
	RFC4	Replication factor C subunit 4. (364 aa)
	A0A4W2D3W4	Ubiquitin-like domain-containing protein. (160 aa)
	UBC	Ubiquitin C. (1146 aa)
	RPA2	RPA_C domain-containing protein. (270 aa)
	CUL4A	Cullin 4A; Belongs to the cullin family. (731 aa)
	POLD1	DNA polymerase. (1106 aa)
	POLE	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2289 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (194 aa)
	A0A4W2C7C3	KxDL domain-containing protein. (179 aa)
	POLD4	Uncharacterized protein. (315 aa)
	DDB1	Damage specific DNA binding protein 1. (1506 aa)
	RFC3	Replication factor C subunit 3. (356 aa)
	RBX1	RING-type domain-containing protein. (128 aa)
	RCBTB1	RCC1 and BTB domain containing protein 1. (531 aa)
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
	WDR48	WD repeat domain 48. (677 aa)
	POLD2	DNA polymerase delta 2, accessory subunit. (580 aa)
	A0A4W2FLF9	RING-type domain-containing protein. (108 aa)
	POLE3	DNA polymerase epsilon 3, accessory subunit. (147 aa)
	CUL4B	Cullin 4B; Belongs to the cullin family. (734 aa)
	KXD1	KxDL domain-containing protein. (212 aa)
	RFC1	Replication factor C subunit 1. (1146 aa)
	UBE2B	Ubiquitin conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family. (180 aa)
	RPA3	Replication protein A3. (121 aa)
	POLE4	DNA polymerase epsilon 4, accessory subunit. (120 aa)
	POLD3	Uncharacterized protein. (425 aa)
	RCBTB2	RCC1 and BTB domain containing protein 2. (554 aa)
	A0A4W2E0Q1	Ubiquitin-like domain-containing protein. (77 aa)
	RFC5	Replication factor C subunit 5. (527 aa)
	A0A4W2DY12	RPA_C domain-containing protein. (270 aa)
	DTL	Denticleless E3 ubiquitin protein ligase homolog. (730 aa)
	RFC2	Replication factor C subunit 2. (352 aa)

Your Current Organism:

Bos indicus

NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A4W2C7C3	A0A4W2D3W4	A0A4W2C7C3	A0A4W2D3W4	KxDL domain-containing protein.	Ubiquitin-like domain-containing protein.	0.488
A0A4W2C7C3	A0A4W2DPH7	A0A4W2C7C3	A0A4W2DPH7	KxDL domain-containing protein.	Ubiquitin-like domain-containing protein.	0.488
A0A4W2C7C3	A0A4W2E0Q1	A0A4W2C7C3	A0A4W2E0Q1	KxDL domain-containing protein.	Ubiquitin-like domain-containing protein.	0.508
A0A4W2C7C3	RPS27A	A0A4W2C7C3	A0A4W2CFE2	KxDL domain-containing protein.	Ubiquitin-like domain-containing protein.	0.488
A0A4W2C7C3	UBC	A0A4W2C7C3	A0A4W2CUP5	KxDL domain-containing protein.	Ubiquitin C.	0.469
A0A4W2D3W4	A0A4W2C7C3	A0A4W2D3W4	A0A4W2C7C3	Ubiquitin-like domain-containing protein.	KxDL domain-containing protein.	0.488
A0A4W2D3W4	A0A4W2E0Q1	A0A4W2D3W4	A0A4W2E0Q1	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.991
A0A4W2D3W4	A0A4W2FLF9	A0A4W2D3W4	A0A4W2FLF9	Ubiquitin-like domain-containing protein.	RING-type domain-containing protein.	0.707
A0A4W2D3W4	ATAD5	A0A4W2D3W4	A0A4W2DM48	Ubiquitin-like domain-containing protein.	ATPase family AAA domain containing 5.	0.403
A0A4W2D3W4	CUL4A	A0A4W2D3W4	A0A4W2CQB2	Ubiquitin-like domain-containing protein.	Cullin 4A; Belongs to the cullin family.	0.492
A0A4W2D3W4	CUL4B	A0A4W2D3W4	A0A4W2F1B6	Ubiquitin-like domain-containing protein.	Cullin 4B; Belongs to the cullin family.	0.492
A0A4W2D3W4	DDB1	A0A4W2D3W4	A0A4W2BSE7	Ubiquitin-like domain-containing protein.	Damage specific DNA binding protein 1.	0.590
A0A4W2D3W4	DTL	A0A4W2D3W4	A0A4W2DXI3	Ubiquitin-like domain-containing protein.	Denticleless E3 ubiquitin protein ligase homolog.	0.509
A0A4W2D3W4	KXD1	A0A4W2D3W4	A0A4W2EY42	Ubiquitin-like domain-containing protein.	KxDL domain-containing protein.	0.488
A0A4W2D3W4	PCNA	A0A4W2D3W4	A0A4W2D824	Ubiquitin-like domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.857
A0A4W2D3W4	POLD1	A0A4W2D3W4	A0A4W2CKC9	Ubiquitin-like domain-containing protein.	DNA polymerase.	0.505
A0A4W2D3W4	POLD3	A0A4W2D3W4	A0A4W2EAR0	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.418
A0A4W2D3W4	POLE2	A0A4W2D3W4	A0A4W2DDJ7	Ubiquitin-like domain-containing protein.	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.	0.506
A0A4W2D3W4	POLE3	A0A4W2D3W4	A0A4W2FHI6	Ubiquitin-like domain-containing protein.	DNA polymerase epsilon 3, accessory subunit.	0.508
A0A4W2D3W4	POLE4	A0A4W2D3W4	A0A4W2EFM3	Ubiquitin-like domain-containing protein.	DNA polymerase epsilon 4, accessory subunit.	0.504

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