STRINGSTRING
PRKCG PRKCG GRIA1 GRIA1 PRKCB PRKCB CAMK2B CAMK2B CAMK2A CAMK2A PRKCA PRKCA A0A4W2E3N8 A0A4W2E3N8 A0A4W2DXS4 A0A4W2DXS4 AP2B1 AP2B1 AP2A2 AP2A2 CAMK2G CAMK2G CACNG2 CACNG2 DLG1 DLG1 MDM2 MDM2 AP2S1 AP2S1 MYO6 MYO6 GRIA2 GRIA2 A0A4W2C3X9 A0A4W2C3X9 PICK1 PICK1 GRIA4 GRIA4 A0A4W2BXG6 A0A4W2BXG6 A0A4W2BT49 A0A4W2BT49 DLG4 DLG4 GRIP2 GRIP2 DLG2 DLG2 NSF NSF CACNG3 CACNG3 CACNG8 CACNG8 GRIP1 GRIP1 CAMK2D CAMK2D AKAP5 AKAP5 AP2M1 AP2M1 A0A4W2EHH7 A0A4W2EHH7 AP2A1 AP2A1 EPB41L1 EPB41L1 CACNG4 CACNG4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (771 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (906 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (830 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
A0A4W2E3N8B2-adapt-app_C domain-containing protein. (266 aa)
A0A4W2DXS4RING-type domain-containing protein. (131 aa)
AP2B1Uncharacterized protein. (995 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (935 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (596 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (300 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa)
MDM2MDM2 proto-oncogene. (689 aa)
AP2S1Adaptor related protein complex 2 subunit sigma 1. (231 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1289 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
A0A4W2C3X9ANF_receptor domain-containing protein. (179 aa)
PICK1Protein interacting with PRKCA 1. (464 aa)
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (902 aa)
A0A4W2BXG6MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (341 aa)
A0A4W2BT49Uncharacterized protein. (72 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (754 aa)
GRIP2Glutamate receptor interacting protein 2. (1045 aa)
DLG2Discs large MAGUK scaffold protein 2. (1009 aa)
NSFN-ethylmaleimide sensitive factor, vesicle fusing ATPase. (797 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (426 aa)
GRIP1Glutamate receptor interacting protein 1. (1128 aa)
CAMK2DProtein kinase domain-containing protein. (544 aa)
AKAP5A-kinase anchoring protein 5. (428 aa)
AP2M1MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (435 aa)
A0A4W2EHH7Uncharacterized protein. (91 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (978 aa)
EPB41L1Erythrocyte membrane protein band 4.1 like 1. (1618 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (321 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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