119 items (Bos indicus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC113875854	Protein kinase domain-containing protein. (258 aa)
	PSMA4	Proteasome subunit alpha type. (261 aa)
	ANAPC4	Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (809 aa)
	PSMD1	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
	PSMA8	Proteasome subunit alpha type. (250 aa)
	PSMC5	Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
	PSMC3	Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (440 aa)
	A0A4W2GF22	DOC domain-containing protein. (83 aa)
	PSMD9	PDZ domain-containing protein. (221 aa)
	PSMD2	Proteasome 26S subunit, non-ATPase 2. (1688 aa)
	PSMA7	Proteasome subunit alpha type. (248 aa)
	LOC113899187	Uncharacterized protein. (202 aa)
	A0A4W2GSS9	Uncharacterized protein. (47 aa)
	NEK2	NIMA related kinase 2. (445 aa)
	FAM89A	Family with sequence similarity 89 member A. (178 aa)
	PSMD7	Proteasome 26S subunit, non-ATPase 7. (322 aa)
	AURKC	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (326 aa)
	PSMB4	Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
	PSME3	Proteasome activator subunit 3. (231 aa)
	CCNA2	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (430 aa)
	PSMD13	Proteasome 26S subunit, non-ATPase 13. (376 aa)
	CDC20	Cell division cycle 20. (499 aa)
	PSMA5	Proteasome subunit alpha type. (241 aa)
	CDK2	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
	A0A4W2HUR1	HORMA domain-containing protein. (197 aa)
	PSMD12	Proteasome 26S subunit, non-ATPase 12. (456 aa)
	A0A4W2HXK5	Uncharacterized protein. (129 aa)
	RB1	RB transcriptional corepressor 1. (928 aa)
	UBE2S	Ubiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (223 aa)
	A0A4W2I5C3	Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (70 aa)
	CDK1	Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
	PSMB10	Proteasome subunit beta. (273 aa)
	A0A4W2I9K4	Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (58 aa)
	PSME1	Proteasome activator subunit 1. (249 aa)
	CCNA1	Cyclin A1; Belongs to the cyclin family. (421 aa)
	PLK1	Serine/threonine-protein kinase PLK. (602 aa)
	A0A4W2BS58	RING-type domain-containing protein. (81 aa)
	A0A4W2BX47	Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (79 aa)
	PSMD3	Proteasome 26S subunit, non-ATPase 3. (534 aa)
	PSMB8	Proteasome subunit beta. (276 aa)
	UBE2E1	Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa)
	ANAPC10	DOC domain-containing protein. (327 aa)
	BTRC	Beta-transducin repeat containing E3 ubiquitin protein ligase. (616 aa)
	UBE2D1	Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
	CDK3	Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (305 aa)
	PSMD11	Proteasome 26S subunit, non-ATPase 11. (437 aa)
	A0A4W2C7C3	KxDL domain-containing protein. (179 aa)
	ANAPC5	Anaphase promoting complex subunit 5. (755 aa)
	ANAPC11	RING-type domain-containing protein. (84 aa)
	ANAPC16	Anaphase promoting complex subunit 16. (110 aa)
	CDC27	Cell division cycle 27. (831 aa)
	PSMA6	Proteasome subunit alpha type. (246 aa)
	PSMC4	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (194 aa)
	PSME4	Proteasome activator subunit 4. (1843 aa)
	ANAPC15	Uncharacterized protein. (121 aa)
	A0A4W2CNN4	Uncharacterized protein. (207 aa)
	RGS22	Regulator of G protein signaling 22. (1254 aa)
	PSMA1	Proteasome subunit alpha type. (269 aa)
	A0A4W2CQU3	Proteasome endopeptidase complex. (239 aa)
	PSMB6	Proteasome subunit beta. (239 aa)
	A0A4W2CR66	PROTEASOME_ALPHA_1 domain-containing protein. (200 aa)
	FBXO43	F-box protein 43. (690 aa)
	ANAPC7	Anaphase promoting complex subunit 7. (598 aa)
	PSMF1	Proteasome inhibitor subunit 1. (270 aa)
	CDC16	Cell division cycle 16. (620 aa)
	UBC	Ubiquitin C. (1146 aa)
	FBXO5	F-box protein 5. (448 aa)
	A0A4W2CWK4	Skp1_POZ domain-containing protein. (65 aa)
	PSMB7	Proteasome subunit beta. (277 aa)
	PSMB1	Proteasome subunit beta. (241 aa)
	FZR1	Fizzy and cell division cycle 20 related 1. (523 aa)
	PSME2	Proteasome activator subunit 2. (239 aa)
	ANAPC1	Anaphase promoting complex subunit 1. (1958 aa)
	A0A4W2D3W4	Ubiquitin-like domain-containing protein. (160 aa)
	CDC26	Cell division cycle 26. (85 aa)
	CDC14A	Cell division cycle 14A. (705 aa)
	PSMB11	Proteasome subunit beta. (289 aa)
	UBE2C	Ubiquitin conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
	A0A4W2D7W0	Uncharacterized protein. (96 aa)
	PSMD4	Proteasome 26S subunit, non-ATPase 4. (385 aa)
	A0A4W2D801	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (274 aa)
	LOC113896623	Uncharacterized protein. (202 aa)
	PSMB2	Proteasome subunit beta. (201 aa)
	PSMC6	Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
	A0A4W2DCT4	Uncharacterized protein. (194 aa)
	AURKA	Aurora kinase A; Belongs to the protein kinase superfamily. (402 aa)
	PTTG1	Uncharacterized protein. (202 aa)
	MAD2L1	HORMA domain-containing protein. (215 aa)
	PSMD5	Proteasome 26S subunit, non-ATPase 5. (554 aa)
	A0A4W2DNY5	Uncharacterized protein. (286 aa)
	A0A4W2DPH7	Ubiquitin-like domain-containing protein. (120 aa)
	ANAPC2	Anaphase promoting complex subunit 2; Belongs to the cullin family. (888 aa)
	BUB3	BUB3 mitotic checkpoint protein. (343 aa)
	CDC23	Cell division cycle 23. (607 aa)
	A0A4W2DXK0	HORMA domain-containing protein. (258 aa)
	A0A4W2E0Q1	Ubiquitin-like domain-containing protein. (77 aa)
	PSMD8	Proteasome 26S subunit, non-ATPase 8. (350 aa)
	KIAA2012	KIAA2012. (1163 aa)
	AURKB	Aurora kinase B; Belongs to the protein kinase superfamily. (406 aa)
	CCNB1	Cyclin B1; Belongs to the cyclin family. (427 aa)
	CDC20B	Cell division cycle 20B. (514 aa)
	A0A4W2EBR9	Uncharacterized protein. (221 aa)
	PSMB9	Proteasome subunit beta. (219 aa)
	BUB1B	Uncharacterized protein. (1062 aa)
	A0A4W2EMD5	Proteasome endopeptidase complex. (296 aa)
	PSMC1	Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (462 aa)
	PSMB5	Proteasome subunit beta. (263 aa)
	A0A4W2ESI7	Proteasome endopeptidase complex. (157 aa)
	PSMA3	Proteasome subunit alpha type. (266 aa)
	PSMD14	Proteasome 26S subunit, non-ATPase 14. (320 aa)
	KXD1	KxDL domain-containing protein. (212 aa)
	TM7SF3	Transmembrane 7 superfamily member 3. (570 aa)
	A0A4W2F2V9	Uncharacterized protein. (63 aa)
	PSMC2	Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
	PSMB3	Proteasome subunit beta. (236 aa)
	SKP2	F-box domain-containing protein. (436 aa)
	SKP1	S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
	CUL1	Cullin 1; Belongs to the cullin family. (776 aa)

Your Current Organism:

Bos indicus

NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A4W2BS58	A0A4W2D3W4	A0A4W2BS58	A0A4W2D3W4	RING-type domain-containing protein.	Ubiquitin-like domain-containing protein.	0.417
A0A4W2BS58	A0A4W2DCT4	A0A4W2BS58	A0A4W2DCT4	RING-type domain-containing protein.	Uncharacterized protein.	0.616
A0A4W2BS58	A0A4W2DPH7	A0A4W2BS58	A0A4W2DPH7	RING-type domain-containing protein.	Ubiquitin-like domain-containing protein.	0.417
A0A4W2BS58	A0A4W2DXK0	A0A4W2BS58	A0A4W2DXK0	RING-type domain-containing protein.	HORMA domain-containing protein.	0.584
A0A4W2BS58	A0A4W2E0Q1	A0A4W2BS58	A0A4W2E0Q1	RING-type domain-containing protein.	Ubiquitin-like domain-containing protein.	0.855
A0A4W2BS58	A0A4W2GF22	A0A4W2BS58	A0A4W2GF22	RING-type domain-containing protein.	DOC domain-containing protein.	0.951
A0A4W2BS58	A0A4W2HUR1	A0A4W2BS58	A0A4W2HUR1	RING-type domain-containing protein.	HORMA domain-containing protein.	0.584
A0A4W2BS58	A0A4W2HXK5	A0A4W2BS58	A0A4W2HXK5	RING-type domain-containing protein.	Uncharacterized protein.	0.958
A0A4W2BS58	ANAPC1	A0A4W2BS58	A0A4W2D2J6	RING-type domain-containing protein.	Anaphase promoting complex subunit 1.	0.984
A0A4W2BS58	ANAPC10	A0A4W2BS58	A0A4W2C1H8	RING-type domain-containing protein.	DOC domain-containing protein.	0.951
A0A4W2BS58	ANAPC15	A0A4W2BS58	A0A4W2CJP5	RING-type domain-containing protein.	Uncharacterized protein.	0.958
A0A4W2BS58	ANAPC16	A0A4W2BS58	A0A4W2CDM2	RING-type domain-containing protein.	Anaphase promoting complex subunit 16.	0.978
A0A4W2BS58	ANAPC2	A0A4W2BS58	A0A4W2DPS9	RING-type domain-containing protein.	Anaphase promoting complex subunit 2; Belongs to the cullin family.	0.988
A0A4W2BS58	ANAPC4	A0A4W2BS58	A0A4W2FY47	RING-type domain-containing protein.	Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family.	0.985
A0A4W2BS58	ANAPC5	A0A4W2BS58	A0A4W2C9H3	RING-type domain-containing protein.	Anaphase promoting complex subunit 5.	0.984
A0A4W2BS58	ANAPC7	A0A4W2BS58	A0A4W2CT20	RING-type domain-containing protein.	Anaphase promoting complex subunit 7.	0.982
A0A4W2BS58	AURKA	A0A4W2BS58	A0A4W2DCW2	RING-type domain-containing protein.	Aurora kinase A; Belongs to the protein kinase superfamily.	0.439
A0A4W2BS58	BUB1B	A0A4W2BS58	A0A4W2EM33	RING-type domain-containing protein.	Uncharacterized protein.	0.917
A0A4W2BS58	BUB3	A0A4W2BS58	A0A4W2DVP3	RING-type domain-containing protein.	BUB3 mitotic checkpoint protein.	0.860
A0A4W2BS58	CCNA1	A0A4W2BS58	A0A4W2BMY9	RING-type domain-containing protein.	Cyclin A1; Belongs to the cyclin family.	0.461

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