57 items (Bos indicus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A4W2D833	Ubiquitin-like domain-containing protein. (61 aa)
	NUP214	Nucleoporin 214. (2141 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (326 aa)
	A0A4W2D7B2	Uncharacterized protein. (83 aa)
	PIAS4	Protein inhibitor of activated STAT 4. (573 aa)
	NUP205	Nucleoporin 205. (2024 aa)
	A0A4W2CSP1	Uncharacterized protein. (319 aa)
	NUP188	Nucleoporin 188. (2017 aa)
	NUP160	Nucleoporin 160. (1402 aa)
	KCTD2	Potassium channel tetramerization domain containing 2. (264 aa)
	TOP2B	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1619 aa)
	NUP85	Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (656 aa)
	SUMO2	Small ubiquitin-related modifier. (95 aa)
	RANGAP1	Ran GTPase activating protein 1. (585 aa)
	NUP50	Nucleoporin 50. (465 aa)
	SEH1L	SEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (360 aa)
	NUP58	Nucleoporin 58. (586 aa)
	SUMO1	Small ubiquitin-related modifier. (101 aa)
	PIAS3	Protein inhibitor of activated STAT 3. (722 aa)
	SUMO3	Ubiquitin-like domain-containing protein. (134 aa)
	POM121C	Uncharacterized protein. (1216 aa)
	NUP35	Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family. (327 aa)
	AURKC	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (326 aa)
	NFATC2IP	Nuclear factor of activated T cells 2 interacting protein. (424 aa)
	NUP43	Nucleoporin 43. (380 aa)
	TOP1	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (769 aa)
	LOC113875854	Protein kinase domain-containing protein. (258 aa)
	NUP155	Nucleoporin 155. (1449 aa)
	A0A4W2F4R9	Uncharacterized protein. (465 aa)
	NUP37	Nucleoporin 37. (326 aa)
	LOC113896675	Uncharacterized protein. (403 aa)
	A0A4W2EQE8	Rad60-SLD domain-containing protein. (83 aa)
	AAAS	Aladin WD repeat nucleoporin. (547 aa)
	A0A4W2EKM6	Small ubiquitin-related modifier. (104 aa)
	NUP107	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (960 aa)
	A0A4W2EHW8	Uncharacterized protein. (64 aa)
	A0A4W2EGW0	Ubiquitin-like domain-containing protein. (80 aa)
	TOP1MT	DNA topoisomerase I mitochondrial. (560 aa)
	A0A4W2EEQ4	Ubiquitin-like domain-containing protein. (72 aa)
	NUP98	Nucleoporin 98. (1816 aa)
	AURKB	Aurora kinase B; Belongs to the protein kinase superfamily. (406 aa)
	BIRC5	Baculoviral IAP repeat containing 5. (142 aa)
	NUP133	Nucleoporin 133. (1156 aa)
	NUP88	Nucleoporin 88. (741 aa)
	NUP93	Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (819 aa)
	TOP2A	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1532 aa)
	INCENP	Inner centromere protein. (877 aa)
	UBE2I	Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
	VTCN1	V-set domain containing T cell activation inhibitor 1. (282 aa)
	NUP210	Nucleoporin 210. (1889 aa)
	NUP210L	Nucleoporin 210 like. (1883 aa)
	CDCA8	Cell division cycle associated 8. (285 aa)
	A0A4W2DES2	Uncharacterized protein. (116 aa)
	NDC1	NDC1 transmembrane nucleoporin. (784 aa)
	RAE1	Ribonucleic acid export 1. (367 aa)
	NUP42	Nucleoporin 42. (420 aa)
	A0A4W2D9I6	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)

Your Current Organism:

Bos indicus

NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A4W2CSP1	NUP42	A0A4W2CSP1	A0A4W2DCC0	Uncharacterized protein.	Nucleoporin 42.	0.402
A0A4W2D7B2	A0A4W2D9I6	A0A4W2D7B2	A0A4W2D9I6	Uncharacterized protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.764
A0A4W2D7B2	A0A4W2EHW8	A0A4W2D7B2	A0A4W2EHW8	Uncharacterized protein.	Uncharacterized protein.	0.587
A0A4W2D7B2	A0A4W2EKM6	A0A4W2D7B2	A0A4W2EKM6	Uncharacterized protein.	Small ubiquitin-related modifier.	0.668
A0A4W2D7B2	KCTD2	A0A4W2D7B2	A0A4W2CK89	Uncharacterized protein.	Potassium channel tetramerization domain containing 2.	0.587
A0A4W2D7B2	NUP93	A0A4W2D7B2	A0A4W2DZZ3	Uncharacterized protein.	Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family.	0.402
A0A4W2D7B2	PCNA	A0A4W2D7B2	A0A4W2D824	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.733
A0A4W2D7B2	PIAS3	A0A4W2D7B2	A0A4W2I813	Uncharacterized protein.	Protein inhibitor of activated STAT 3.	0.695
A0A4W2D7B2	PIAS4	A0A4W2D7B2	A0A4W2D5V0	Uncharacterized protein.	Protein inhibitor of activated STAT 4.	0.784
A0A4W2D7B2	RANGAP1	A0A4W2D7B2	A0A4W2C029	Uncharacterized protein.	Ran GTPase activating protein 1.	0.830
A0A4W2D7B2	SUMO2	A0A4W2D7B2	A0A4W2C4P5	Uncharacterized protein.	Small ubiquitin-related modifier.	0.685
A0A4W2D7B2	TOP1	A0A4W2D7B2	A0A4W2FQZ6	Uncharacterized protein.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]	0.418
A0A4W2D7B2	TOP1MT	A0A4W2D7B2	A0A4W2EFR3	Uncharacterized protein.	DNA topoisomerase I mitochondrial.	0.410
A0A4W2D7B2	TOP2A	A0A4W2D7B2	A0A4W2DY76	Uncharacterized protein.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.453
A0A4W2D7B2	TOP2B	A0A4W2D7B2	A0A4W2CJG8	Uncharacterized protein.	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.453
A0A4W2D7B2	UBE2I	A0A4W2D7B2	A0A4W2DR12	Uncharacterized protein.	Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.	0.764
A0A4W2D833	A0A4W2D9I6	A0A4W2D833	A0A4W2D9I6	Ubiquitin-like domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.743
A0A4W2D833	A0A4W2EHW8	A0A4W2D833	A0A4W2EHW8	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.587
A0A4W2D833	A0A4W2EKM6	A0A4W2D833	A0A4W2EKM6	Ubiquitin-like domain-containing protein.	Small ubiquitin-related modifier.	0.668
A0A4W2D833	KCTD2	A0A4W2D833	A0A4W2CK89	Ubiquitin-like domain-containing protein.	Potassium channel tetramerization domain containing 2.	0.587

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