STRINGSTRING
PMS2 PMS2 POLD2 POLD2 POLD3 POLD3 MSH6 MSH6 MSH3 MSH3 EXO1 EXO1 RPA1 RPA1 MSH2 MSH2 A0A4W2DY12 A0A4W2DY12 MEIOB MEIOB PMS1 PMS1 PCNA PCNA A0A4W2CYF2 A0A4W2CYF2 RPA2 RPA2 POLD1 POLD1 RPA3 RPA3 MLH1 MLH1 POLD4 POLD4 LIG1 LIG1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PMS2MutL_C domain-containing protein. (461 aa)
POLD2DNA polymerase delta 2, accessory subunit. (580 aa)
POLD3Uncharacterized protein. (425 aa)
MSH6DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1361 aa)
MSH3DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1118 aa)
EXO1Exonuclease 1. (835 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa)
A0A4W2DY12RPA_C domain-containing protein. (270 aa)
MEIOBMeiosis specific with OB-fold. (472 aa)
PMS1PMS1 homolog 1, mismatch repair system component. (915 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (326 aa)
A0A4W2CYF2PWWP domain-containing protein. (159 aa)
RPA2RPA_C domain-containing protein. (270 aa)
POLD1DNA polymerase. (1106 aa)
RPA3Replication protein A3. (121 aa)
MLH1MutL homolog 1. (758 aa)
POLD4Uncharacterized protein. (315 aa)
LIG1DNA ligase. (1303 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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