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| | A0A4W2DXS4 | RING-type domain-containing protein. (131 aa) |
| | A0A4W2DY12 | RPA_C domain-containing protein. (270 aa) |
| | BLM | BLM RecQ like helicase. (1430 aa) |
| | BRD1 | Bromodomain containing 1. (1182 aa) |
| | TAF1 | Transcription initiation factor TFIID subunit. (1928 aa) |
| | RFC5 | Replication factor C subunit 5. (527 aa) |
| | A0A4W2E0Q1 | Ubiquitin-like domain-containing protein. (77 aa) |
| | PIP4K2B | Phosphatidylinositol-5-phosphate 4-kinase type 2 beta. (416 aa) |
| | ZNF385C | Zinc finger protein 385C. (516 aa) |
| | CHD3 | Chromodomain helicase DNA binding protein 3. (2059 aa) |
| | A0A4W2EHH7 | Uncharacterized protein. (91 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | TBPL1 | TATA-box binding protein like 1. (186 aa) |
| | CCNA2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (430 aa) |
| | BRPF1 | Uncharacterized protein. (1214 aa) |
| | BRD9 | Bromodomain containing 9. (616 aa) |
| | TAF2 | TATA-box binding protein associated factor 2. (1251 aa) |
| | AURKC | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (326 aa) |
| | EHMT1 | Euchromatic histone lysine methyltransferase 1. (1293 aa) |
| | TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa) |
| | PRDM1 | PR/SET domain 1. (842 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (309 aa) |
| | HDAC2 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa) |
| | TBPL2 | TATA-box binding protein like 2. (325 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (574 aa) |
| | SETD9 | SET domain containing 9. (299 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | TP53INP1 | Tumor protein p53 inducible nuclear protein 1. (240 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa) |
| | RMI2 | RecQ mediated genome instability 2. (157 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (565 aa) |
| | HIPK4 | Homeodomain interacting protein kinase 4. (616 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (499 aa) |
| | TAF4 | TATA-box binding protein associated factor 4. (1061 aa) |
| | CDK1 | Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa) |
| | CDK5R2 | Cyclin dependent kinase 5 regulatory subunit 2. (412 aa) |
| | EXO1 | Exonuclease 1. (835 aa) |
| | TP53INP2 | Tumor protein p53 inducible nuclear protein 2. (224 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (438 aa) |
| | CHEK2 | Checkpoint kinase 2. (534 aa) |
| | DYRK4 | Dual specificity tyrosine phosphorylation regulated kinase 4. (649 aa) |
| | NUAK2 | NUAK family kinase 2. (644 aa) |
| | AURKB | Aurora kinase B; Belongs to the protein kinase superfamily. (406 aa) |
| | PPP1R13L | Protein phosphatase 1 regulatory subunit 13 like. (919 aa) |
| | PPP2R5C | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (578 aa) |
| | TP53RK | TP53 regulating kinase. (253 aa) |
| | RNF34 | Ring finger protein 34. (442 aa) |
| | PML | Promyelocytic leukemia. (871 aa) |
| | BRCA1 | BRCA1 DNA repair associated. (1941 aa) |
| | TAF3 | TATA-box binding protein associated factor 3. (932 aa) |
| | HDAC1 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (513 aa) |
| | PRR5 | Proline rich 5. (409 aa) |
| | CSNK2A1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (452 aa) |
| | BRPF3 | Bromodomain and PHD finger containing 3. (1207 aa) |
| | PRKAG3 | Protein kinase AMP-activated non-catalytic subunit gamma 3. (535 aa) |
| | CHD4 | Uncharacterized protein. (1920 aa) |
| | USP7 | Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1103 aa) |
| | RFC3 | Replication factor C subunit 3. (356 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (421 aa) |
| | RFFL | Ring finger and FYVE like domain containing E3 ubiquitin protein ligase. (385 aa) |
| | MTA2 | Metastasis associated 1 family member 2. (672 aa) |
| | TDRD3 | Tudor domain containing 3. (744 aa) |
| | BRIP1 | BRCA1 interacting protein C-terminal helicase 1. (1172 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa) |
| | ATRIP | ATR interacting protein. (789 aa) |
| | A0A4W2BU60 | Uncharacterized protein. (82 aa) |
| | TAF4B | TATA-box binding protein associated factor 4b. (869 aa) |
| | WRN | WRN RecQ like helicase. (1409 aa) |
| | KAT6A | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2018 aa) |
| | A0A4W2BX41 | TAFII28 domain-containing protein. (193 aa) |
| | POU4F2 | POU domain protein. (408 aa) |
| | MRE11 | MRE11 homolog, double strand break repair nuclease; Belongs to the MRE11/RAD32 family. (943 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (364 aa) |
| | EP300 | E1A binding protein p300. (2411 aa) |
| | FOXP4 | Forkhead box P4. (746 aa) |
| | DAXX | Death domain associated protein. (735 aa) |
| | SUPT16H | SPT16 homolog, facilitates chromatin remodeling subunit. (1047 aa) |
| | TTC5 | Tetratricopeptide repeat domain 5. (451 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (1061 aa) |
| | CSNK2A2 | Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (385 aa) |
| | POU4F3 | POU domain protein. (338 aa) |
| | MAPKAP1 | MAPK associated protein 1. (522 aa) |
| | CSNK2B | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (235 aa) |
| | TP73 | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (640 aa) |
| | ING2 | Inhibitor of growth protein. (284 aa) |
| | TAF5 | TATA-box binding protein associated factor 5. (800 aa) |
| | HIPK3 | Homeodomain interacting protein kinase 3. (1216 aa) |
| | TOP3A | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1002 aa) |
| | TXNDC11 | Thioredoxin domain containing 11. (956 aa) |
| | A0A4W2FPD6 | Uncharacterized protein. (53 aa) |
| | PIP4K2C | Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (421 aa) |
| | TAF11 | TATA-box binding protein associated factor 11. (210 aa) |
| | LOC113875854 | Protein kinase domain-containing protein. (258 aa) |
| | PHF20 | PHD finger protein 20. (1010 aa) |
| | DYRK3 | Dual specificity tyrosine phosphorylation regulated kinase 3. (587 aa) |
| | PLK3 | Serine/threonine-protein kinase PLK. (647 aa) |
| | JMY | Junction mediating and regulatory protein, p53 cofactor. (991 aa) |
| | AIRE | Autoimmune regulator. (565 aa) |
| | PIN1 | Peptidyl-prolyl cis-trans isomerase. (163 aa) |
| | CCNG1 | CYCLIN domain-containing protein; Belongs to the cyclin family. (295 aa) |
| | NUAK1 | NUAK family kinase 1. (662 aa) |
| | TOPBP1 | DNA topoisomerase II binding protein 1. (1521 aa) |
| | A0A4W2EYQ3 | CAF1C_H4-bd domain-containing protein. (93 aa) |
| | KXD1 | KxDL domain-containing protein. (212 aa) |
| | RPA3 | Replication protein A3. (121 aa) |
| | ZNF385B | Zinc finger protein 385B. (486 aa) |
| | HIPK1 | Homeodomain interacting protein kinase 1. (1233 aa) |
| | HIPK2 | Homeodomain interacting protein kinase 2. (1205 aa) |
| | TBP | Uncharacterized protein. (318 aa) |
| | L3MBTL1 | Uncharacterized protein. (864 aa) |
| | TPX2 | TPX2 microtubule nucleation factor. (747 aa) |
| | CHD5 | Chromodomain helicase DNA binding protein 5. (1953 aa) |
| | BARD1 | BRCA1 associated RING domain 1. (773 aa) |
| | TAF6 | TATA-box binding protein associated factor 6. (740 aa) |
| | EHMT2 | Euchromatic histone lysine methyltransferase 2. (1389 aa) |
| | RHNO1 | RAD9-HUS1-RAD1 interacting nuclear orphan 1. (241 aa) |
| | PPP1R13B | Protein phosphatase 1 regulatory subunit 13B. (1136 aa) |
| | TAF10 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa) |
| | RAD17 | RAD17 checkpoint clamp loader component. (708 aa) |
| | RAD9B | Cell cycle checkpoint control protein; Belongs to the rad9 family. (417 aa) |
| | BRD7 | Bromodomain containing 7. (853 aa) |
| | TP53BP2 | Tumor protein p53 binding protein 2. (1244 aa) |
| | A0A4W2C4Q6 | Uncharacterized protein. (167 aa) |
| | CDK3 | Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (305 aa) |
| | BANP | BTG3 associated nuclear protein. (647 aa) |
| | A0A4W2C7C3 | KxDL domain-containing protein. (179 aa) |
| | A0A4W2C7Q9 | Uncharacterized protein. (622 aa) |
| | NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (809 aa) |
| | MAPKAPK5 | MAPK activated protein kinase 5. (470 aa) |
| | TAF9 | TATA-box binding protein associated factor 9. (264 aa) |
| | A0A4W2CCQ9 | Uncharacterized protein. (303 aa) |
| | KMT5A | Lysine methyltransferase 5A. (352 aa) |
| | PIP4P2 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (275 aa) |
| | C17orf113 | Chromosome 17 open reading frame 113. (675 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (805 aa) |
| | RICTOR | RPTOR independent companion of MTOR complex 2. (1789 aa) |
| | A0A4W2CET6 | Serine/threonine-protein phosphatase. (259 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (194 aa) |
| | RAD1 | RAD1 checkpoint DNA exonuclease. (279 aa) |
| | MDM4 | Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (491 aa) |
| | A0A4W2CH33 | Metallophos domain-containing protein. (127 aa) |
| | SSRP1 | Structure specific recognition protein 1. (852 aa) |
| | A0A4W2CJR6 | TFIID_20kDa domain-containing protein. (152 aa) |
| | PIP4K2A | Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (405 aa) |
| | L3MBTL3 | L3MBTL histone methyl-lysine binding protein 3. (779 aa) |
| | PRKAB1 | Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa) |
| | MDM2 | MDM2 proto-oncogene. (689 aa) |
| | TAF12 | TFIID_20kDa domain-containing protein. (161 aa) |
| | RPA2 | RPA_C domain-containing protein. (270 aa) |
| | A0A4W2CUF7 | Inhibitor of growth protein. (278 aa) |
| | UBC | Ubiquitin C. (1146 aa) |
| | RBBP4 | RB binding protein 4, chromatin remodeling factor. (425 aa) |
| | SGK1 | Non-specific serine/threonine protein kinase. (526 aa) |
| | DYRK2 | Dual specificity tyrosine phosphorylation regulated kinase 2. (599 aa) |
| | A0A4W2CXP8 | TAFII28 domain-containing protein. (200 aa) |
| | PPP2R1A | Protein phosphatase 2 scaffold subunit Aalpha. (589 aa) |
| | POU4F1 | POU domain protein. (421 aa) |
| | ZNF385A | Zinc finger protein 385A. (393 aa) |
| | PRKAG1 | Protein kinase AMP-activated non-catalytic subunit gamma 1. (330 aa) |
| | SLF1 | SMC5-SMC6 complex localization factor 1. (1175 aa) |
| | A0A4W2D2X3 | Zinc-hook domain-containing protein. (1440 aa) |
| | EXD2 | Exonuclease 3'-5' domain containing 2. (628 aa) |
| | A0A4W2D3W4 | Ubiquitin-like domain-containing protein. (160 aa) |
| | NOC2L | NOC2 like nucleolar associated transcriptional repressor. (754 aa) |
| | RFC4 | Replication factor C subunit 4. (364 aa) |
| | A0A4W2D801 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (274 aa) |
| | CDK5 | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa) |
| | AURKA | Aurora kinase A; Belongs to the protein kinase superfamily. (402 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) |
| | GATAD2B | GATA zinc finger domain containing 2B. (592 aa) |
| | ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa) |
| | MEIOB | Meiosis specific with OB-fold. (472 aa) |
| | PRMT5 | Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (620 aa) |
| | A0A4W2DPH7 | Ubiquitin-like domain-containing protein. (120 aa) |
| | RBBP8 | RB binding protein 8, endonuclease. (859 aa) |
| | RMI1 | RecQ mediated genome instability 1. (624 aa) |
| | RFC2 | Replication factor C subunit 2. (352 aa) |
| | CHEK1 | Checkpoint kinase 1. (677 aa) |
| | ING5 | ING domain-containing protein. (366 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3054 aa) |
| | MBD3 | Methyl-CpG binding domain protein 3. (289 aa) |
| | LY6G5B | Lymphocyte antigen 6 family member G5B. (200 aa) |
| | GATAD2A | GATA zinc finger domain containing 2A. (876 aa) |
| | RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (422 aa) |
| | A0A4W2EHQ1 | Uncharacterized protein. (245 aa) |
| | HUS1 | Checkpoint protein; Belongs to the HUS1 family. (280 aa) |
