STRINGSTRING
RCBTB2 RCBTB2 RFC1 RFC1 KXD1 KXD1 POLE3 POLE3 POLD2 POLD2 RPA1 RPA1 RCBTB1 RCBTB1 POLD3 POLD3 ISG15 ISG15 RFC3 RFC3 POLD4 POLD4 UBA7 UBA7 A0A4W2C218 A0A4W2C218 USP43 USP43 A0A4W2C7C3 A0A4W2C7C3 RPS27A RPS27A POLE POLE POLD1 POLD1 POLE4 POLE4 TRIM47 TRIM47 UBE2L6 UBE2L6 A0A4W2EP37 A0A4W2EP37 RPA3 RPA3 TRIM65 TRIM65 USP10 USP10 RPA2 RPA2 UBC UBC REV1 REV1 PCLAF PCLAF A0A4W2D3W4 A0A4W2D3W4 RFC4 RFC4 PCNA PCNA POLK POLK POLE2 POLE2 MEIOB MEIOB ATAD5 ATAD5 USP31 USP31 A0A4W2DPH7 A0A4W2DPH7 POLI POLI RFC2 RFC2 POLH POLH TRIM25 TRIM25 A0A4W2DY12 A0A4W2DY12 RFC5 RFC5 A0A4W2E0Q1 A0A4W2E0Q1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RCBTB2RCC1 and BTB domain containing protein 2. (554 aa)
RFC1Replication factor C subunit 1. (1146 aa)
KXD1KxDL domain-containing protein. (212 aa)
POLE3DNA polymerase epsilon 3, accessory subunit. (147 aa)
POLD2DNA polymerase delta 2, accessory subunit. (580 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
POLD3Uncharacterized protein. (425 aa)
ISG15ISG15 ubiquitin like modifier. (154 aa)
RFC3Replication factor C subunit 3. (356 aa)
POLD4Uncharacterized protein. (315 aa)
UBA7Ubiquitin like modifier activating enzyme 7. (1001 aa)
A0A4W2C218Uncharacterized protein. (627 aa)
USP43Ubiquitin specific peptidase 43; Belongs to the peptidase C19 family. (1138 aa)
A0A4W2C7C3KxDL domain-containing protein. (179 aa)
RPS27AUbiquitin-like domain-containing protein. (194 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2289 aa)
POLD1DNA polymerase. (1106 aa)
POLE4DNA polymerase epsilon 4, accessory subunit. (120 aa)
TRIM47Tripartite motif containing 47. (649 aa)
UBE2L6Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
A0A4W2EP37PAF domain-containing protein. (92 aa)
RPA3Replication protein A3. (121 aa)
TRIM65Tripartite motif containing 65. (548 aa)
USP10Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (800 aa)
RPA2RPA_C domain-containing protein. (270 aa)
UBCUbiquitin C. (1146 aa)
REV1DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1253 aa)
PCLAFPAF domain-containing protein. (114 aa)
A0A4W2D3W4Ubiquitin-like domain-containing protein. (160 aa)
RFC4Replication factor C subunit 4. (364 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (326 aa)
POLKDNA polymerase kappa. (911 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
MEIOBMeiosis specific with OB-fold. (472 aa)
ATAD5ATPase family AAA domain containing 5. (1893 aa)
USP31Ubiquitin specific peptidase 31; Belongs to the peptidase C19 family. (1347 aa)
A0A4W2DPH7Ubiquitin-like domain-containing protein. (120 aa)
POLIDNA polymerase iota. (760 aa)
RFC2Replication factor C subunit 2. (352 aa)
POLHDNA polymerase eta. (711 aa)
TRIM25Tripartite motif containing 25. (631 aa)
A0A4W2DY12RPA_C domain-containing protein. (270 aa)
RFC5Replication factor C subunit 5. (527 aa)
A0A4W2E0Q1Ubiquitin-like domain-containing protein. (77 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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