(38 nodes) Cargo concentration in the ER network (Bos indicus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A4W2BLS1	Uncharacterized protein. (208 aa)
	CTSC	Cathepsin C; Belongs to the peptidase C1 family. (463 aa)
	STX5	Syntaxin 5; Belongs to the syntaxin family. (355 aa)
	CNIH2	Cornichon family AMPA receptor auxiliary protein 2. (160 aa)
	LMAN1	Lectin, mannose binding 1. (568 aa)
	MIA2	SH3 domain-containing protein. (1409 aa)
	TMED2	GOLD domain-containing protein. (201 aa)
	A0A4W2CKS2	Uncharacterized protein. (335 aa)
	CNIH1	Cornichon family AMPA receptor auxiliary protein 1. (160 aa)
	MIA3	MIA SH3 domain ER export factor 3. (1929 aa)
	LYZL6	Uncharacterized protein; Belongs to the glycosyl hydrolase 22 family. (335 aa)
	PREB	Prolactin regulatory element binding. (418 aa)
	CNIH4	Cornichon family AMPA receptor auxiliary protein 4. (139 aa)
	A0A4W2CYK1	Uncharacterized protein. (89 aa)
	A0A4W2D4F7	Uncharacterized protein. (145 aa)
	SEC23B	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (767 aa)
	LMAN2	Lectin, mannose binding 2. (429 aa)
	SEC24A	SEC24 homolog A, COPII coat complex component. (1090 aa)
	SEC24B	SEC24 homolog B, COPII coat complex component. (1459 aa)
	SERPINA1	SERPIN domain-containing protein; Belongs to the serpin family. (416 aa)
	SEC23A	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (765 aa)
	A0A4W2E2Q1	L-type lectin-like domain-containing protein. (183 aa)
	A0A4W2E992	UPAR/Ly6 domain-containing protein. (121 aa)
	SEC24C	SEC24 homolog C, COPII coat complex component. (1117 aa)
	CTSZ	Cathepsin Z; Belongs to the peptidase C1 family. (396 aa)
	CNIH3	Cornichon family AMPA receptor auxiliary protein 3. (190 aa)
	A0A4W2EL90	Uncharacterized protein. (136 aa)
	LMAN2L	Lectin, mannose binding 2 like. (376 aa)
	A0A4W2EPT3	GOLD domain-containing protein. (201 aa)
	TMED10	Transmembrane p24 trafficking protein 10. (219 aa)
	AREG	Amphiregulin. (247 aa)
	A0A4W2EW97	Uncharacterized protein. (217 aa)
	SAR1B	Secretion associated Ras related GTPase 1B; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
	SAR1A	Secretion associated Ras related GTPase 1A; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
	SEC22B	SEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family. (215 aa)
	SEC24D	SEC24 homolog D, COPII coat complex component. (1032 aa)
	GRIA1	Glutamate ionotropic receptor AMPA type subunit 1. (906 aa)
	TGFA	Transforming growth factor alpha. (228 aa)

Your Current Organism:

Bos indicus

NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A4W2BLS1	A0A4W2CKS2	A0A4W2BLS1	A0A4W2CKS2	Uncharacterized protein.	Uncharacterized protein.	0.536
A0A4W2BLS1	A0A4W2CYK1	A0A4W2BLS1	A0A4W2CYK1	Uncharacterized protein.	Uncharacterized protein.	0.536
A0A4W2BLS1	A0A4W2D4F7	A0A4W2BLS1	A0A4W2D4F7	Uncharacterized protein.	Uncharacterized protein.	0.536
A0A4W2BLS1	A0A4W2E2Q1	A0A4W2BLS1	A0A4W2E2Q1	Uncharacterized protein.	L-type lectin-like domain-containing protein.	0.430
A0A4W2BLS1	CTSC	A0A4W2BLS1	A0A4W2BM59	Uncharacterized protein.	Cathepsin C; Belongs to the peptidase C1 family.	0.612
A0A4W2BLS1	CTSZ	A0A4W2BLS1	A0A4W2EBZ4	Uncharacterized protein.	Cathepsin Z; Belongs to the peptidase C1 family.	0.589
A0A4W2BLS1	LMAN1	A0A4W2BLS1	A0A4W2BVX3	Uncharacterized protein.	Lectin, mannose binding 1.	0.683
A0A4W2BLS1	SAR1A	A0A4W2BLS1	A0A4W2G4Q6	Uncharacterized protein.	Secretion associated Ras related GTPase 1A; Belongs to the small GTPase superfamily. SAR1 family.	0.507
A0A4W2BLS1	SAR1B	A0A4W2BLS1	A0A4W2FGY2	Uncharacterized protein.	Secretion associated Ras related GTPase 1B; Belongs to the small GTPase superfamily. SAR1 family.	0.507
A0A4W2CKS2	A0A4W2BLS1	A0A4W2CKS2	A0A4W2BLS1	Uncharacterized protein.	Uncharacterized protein.	0.536
A0A4W2CKS2	A0A4W2E2Q1	A0A4W2CKS2	A0A4W2E2Q1	Uncharacterized protein.	L-type lectin-like domain-containing protein.	0.794
A0A4W2CKS2	CTSC	A0A4W2CKS2	A0A4W2BM59	Uncharacterized protein.	Cathepsin C; Belongs to the peptidase C1 family.	0.540
A0A4W2CKS2	CTSZ	A0A4W2CKS2	A0A4W2EBZ4	Uncharacterized protein.	Cathepsin Z; Belongs to the peptidase C1 family.	0.575
A0A4W2CKS2	LMAN1	A0A4W2CKS2	A0A4W2BVX3	Uncharacterized protein.	Lectin, mannose binding 1.	0.981
A0A4W2CKS2	LMAN2	A0A4W2CKS2	A0A4W2D603	Uncharacterized protein.	Lectin, mannose binding 2.	0.494
A0A4W2CKS2	LMAN2L	A0A4W2CKS2	A0A4W2EMU4	Uncharacterized protein.	Lectin, mannose binding 2 like.	0.494
A0A4W2CKS2	LYZL6	A0A4W2CKS2	A0A4W2CVA3	Uncharacterized protein.	Uncharacterized protein; Belongs to the glycosyl hydrolase 22 family.	0.419
A0A4W2CKS2	PREB	A0A4W2CKS2	A0A4W2CX88	Uncharacterized protein.	Prolactin regulatory element binding.	0.407
A0A4W2CKS2	SAR1B	A0A4W2CKS2	A0A4W2FGY2	Uncharacterized protein.	Secretion associated Ras related GTPase 1B; Belongs to the small GTPase superfamily. SAR1 family.	0.450
A0A4W2CKS2	SEC22B	A0A4W2CKS2	A0A4W2GMD8	Uncharacterized protein.	SEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family.	0.438

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