STRINGSTRING
PIAS3 PIAS3 PARP3 PARP3 GTF2H1 GTF2H1 XPC XPC DDB1 DDB1 SUMO2 SUMO2 GTF2H4 GTF2H4 A0A4W2C7C3 A0A4W2C7C3 WDR76 WDR76 GTF2H3 GTF2H3 USP45 USP45 RPS27A RPS27A ERCC1 ERCC1 KCTD2 KCTD2 CUL4A CUL4A XPA XPA RPA2 RPA2 UBC UBC PARP1 PARP1 PARP2 PARP2 RAD23B RAD23B A0A4W2D3W4 A0A4W2D3W4 PIAS1 PIAS1 A0A4W2D7B2 A0A4W2D7B2 A0A4W2D833 A0A4W2D833 VWA5B2 VWA5B2 A0A4W2D9I6 A0A4W2D9I6 A0A4W2DES2 A0A4W2DES2 CCNH CCNH MEIOB MEIOB UBE2N UBE2N ERCC3 ERCC3 A0A4W2DPA1 A0A4W2DPA1 A0A4W2DPH7 A0A4W2DPH7 VTCN1 VTCN1 UBE2I UBE2I A0A4W2DY12 A0A4W2DY12 A0A4W2E0Q1 A0A4W2E0Q1 A0A4W2E732 A0A4W2E732 UBE2V2 UBE2V2 A0A4W2EEQ4 A0A4W2EEQ4 A0A4W2EGW0 A0A4W2EGW0 A0A4W2EGX9 A0A4W2EGX9 A0A4W2EHW8 A0A4W2EHW8 A0A4W2EKM6 A0A4W2EKM6 ERCC5 ERCC5 A0A4W2EMF1 A0A4W2EMF1 A0A4W2EQE8 A0A4W2EQE8 CHD1L CHD1L RPA3 RPA3 VWA5B1 VWA5B1 KXD1 KXD1 CUL4B CUL4B MNAT1 MNAT1 A0A4W2FLF9 A0A4W2FLF9 ERCC4 ERCC4 RNF111 RNF111 ERCC2 ERCC2 NFATC2IP NFATC2IP VWA5A VWA5A RPA1 RPA1 DDB2 DDB2 CDK7 CDK7 LOC113878849 LOC113878849 SUMO3 SUMO3 RAD23A RAD23A RBX1 RBX1 CETN3 CETN3 SUMO1 SUMO1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIAS3Protein inhibitor of activated STAT 3. (722 aa)
PARP3Poly [ADP-ribose] polymerase. (515 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
XPCXPC complex subunit, DNA damage recognition and repair factor. (932 aa)
DDB1Damage specific DNA binding protein 1. (1506 aa)
SUMO2Small ubiquitin-related modifier. (95 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (463 aa)
A0A4W2C7C3KxDL domain-containing protein. (179 aa)
WDR76WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (627 aa)
GTF2H3General transcription factor IIH subunit 3. (402 aa)
USP45Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (817 aa)
RPS27AUbiquitin-like domain-containing protein. (194 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (351 aa)
KCTD2Potassium channel tetramerization domain containing 2. (264 aa)
CUL4ACullin 4A; Belongs to the cullin family. (731 aa)
XPAXPA, DNA damage recognition and repair factor. (273 aa)
RPA2RPA_C domain-containing protein. (270 aa)
UBCUbiquitin C. (1146 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1016 aa)
PARP2Poly [ADP-ribose] polymerase. (577 aa)
RAD23BUncharacterized protein. (408 aa)
A0A4W2D3W4Ubiquitin-like domain-containing protein. (160 aa)
PIAS1Protein inhibitor of activated STAT 1. (702 aa)
A0A4W2D7B2Uncharacterized protein. (83 aa)
A0A4W2D833Ubiquitin-like domain-containing protein. (61 aa)
VWA5B2Von Willebrand factor A domain containing 5B2. (1247 aa)
A0A4W2D9I6UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
A0A4W2DES2Uncharacterized protein. (116 aa)
CCNHCyclin H; Belongs to the cyclin family. (329 aa)
MEIOBMeiosis specific with OB-fold. (472 aa)
UBE2NUbiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (780 aa)
A0A4W2DPA1Uncharacterized protein. (334 aa)
A0A4W2DPH7Ubiquitin-like domain-containing protein. (120 aa)
VTCN1V-set domain containing T cell activation inhibitor 1. (282 aa)
UBE2IUbiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
A0A4W2DY12RPA_C domain-containing protein. (270 aa)
A0A4W2E0Q1Ubiquitin-like domain-containing protein. (77 aa)
A0A4W2E732UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (106 aa)
UBE2V2Ubiquitin conjugating enzyme E2 V2. (212 aa)
A0A4W2EEQ4Ubiquitin-like domain-containing protein. (72 aa)
A0A4W2EGW0Ubiquitin-like domain-containing protein. (80 aa)
A0A4W2EGX9Uncharacterized protein. (502 aa)
A0A4W2EHW8Uncharacterized protein. (64 aa)
A0A4W2EKM6Small ubiquitin-related modifier. (104 aa)
ERCC5ERCC excision repair 5, endonuclease. (1201 aa)
A0A4W2EMF1Uncharacterized protein. (286 aa)
A0A4W2EQE8Rad60-SLD domain-containing protein. (83 aa)
CHD1LChromodomain helicase DNA binding protein 1 like. (897 aa)
RPA3Replication protein A3. (121 aa)
VWA5B1Von Willebrand factor A domain containing 5B1. (1208 aa)
KXD1KxDL domain-containing protein. (212 aa)
CUL4BCullin 4B; Belongs to the cullin family. (734 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
A0A4W2FLF9RING-type domain-containing protein. (108 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (916 aa)
RNF111Ring finger protein 111. (1003 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (800 aa)
NFATC2IPNuclear factor of activated T cells 2 interacting protein. (424 aa)
VWA5AVon Willebrand factor A domain containing 5A. (785 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
DDB2Damage specific DNA binding protein 2. (426 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
LOC113878849General transcription factor IIH subunit. (405 aa)
SUMO3Ubiquitin-like domain-containing protein. (134 aa)
RAD23ARAD23 homolog A, nucleotide excision repair protein. (363 aa)
RBX1RING-type domain-containing protein. (128 aa)
CETN3Centrin 3. (167 aa)
SUMO1Small ubiquitin-related modifier. (101 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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