STRINGSTRING
RPA2 RPA2 RBX1 RBX1 TCEA1 TCEA1 A0A4W2IDW0 A0A4W2IDW0 RCBTB1 RCBTB1 LOC113878849 LOC113878849 CDK7 CDK7 ERCC8 ERCC8 POLR2G POLR2G RPA1 RPA1 XAB2 XAB2 LOC113887708 LOC113887708 TCEA3 TCEA3 USP40 USP40 POLR2H POLR2H ERCC2 ERCC2 POLD2 POLD2 TCEA2 TCEA2 POLR2C POLR2C ERCC4 ERCC4 A0A4W2FLF9 A0A4W2FLF9 POLE3 POLE3 MNAT1 MNAT1 POLR2B POLR2B POLR2D POLR2D CUL4B CUL4B KXD1 KXD1 RFC1 RFC1 RPA3 RPA3 A0A4W2EMF1 A0A4W2EMF1 AQR AQR ERCC5 ERCC5 POLR2I POLR2I A0A4W2EIH1 A0A4W2EIH1 A0A4W2EHM9 A0A4W2EHM9 A0A4W2EGX9 A0A4W2EGX9 POLE4 POLE4 POLD3 POLD3 A0A4W2E7G3 A0A4W2E7G3 RCBTB2 RCBTB2 A0A4W2E0Q1 A0A4W2E0Q1 RFC5 RFC5 A0A4W2DYM9 A0A4W2DYM9 A0A4W2DY12 A0A4W2DY12 A0A4W2DUD8 A0A4W2DUD8 ISY1 ISY1 RFC2 RFC2 A0A4W2DPH7 A0A4W2DPH7 ERCC3 ERCC3 PRPF19 PRPF19 ATAD5 ATAD5 MEIOB MEIOB POLR2J POLR2J A0A4W2DJ46 A0A4W2DJ46 NRDE2 NRDE2 CCNH CCNH TCEANC2 TCEANC2 POLE2 POLE2 POLK POLK PPIE PPIE PCNA PCNA RFC4 RFC4 A0A4W2D3W4 A0A4W2D3W4 UVSSA UVSSA ERCC6 ERCC6 HMGN2 HMGN2 SPOCD1 SPOCD1 UBC UBC XPA XPA CUL4A CUL4A POLD1 POLD1 ERCC1 ERCC1 POLE POLE RPS27A RPS27A GTF2H3 GTF2H3 A0A4W2C7C3 A0A4W2C7C3 LOC113881217 LOC113881217 PHF3 PHF3 POLR2A POLR2A POLR2F POLR2F GTF2H4 GTF2H4 EP300 EP300 POLR2E POLR2E POLD4 POLD4 ZNF830 ZNF830 POLR2L POLR2L DDB1 DDB1 GTF2H1 GTF2H1 RFC3 RFC3 UPK3BL2 UPK3BL2 USP7 USP7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RPA2RPA_C domain-containing protein. (270 aa)
RBX1RING-type domain-containing protein. (128 aa)
TCEA1Transcription elongation factor A1. (301 aa)
A0A4W2IDW0Uncharacterized protein. (90 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
LOC113878849General transcription factor IIH subunit. (405 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (397 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
XAB2XPA binding protein 2. (855 aa)
LOC113887708Uncharacterized protein. (377 aa)
TCEA3Transcription elongation factor A3. (349 aa)
USP40Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family. (1338 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (800 aa)
POLD2DNA polymerase delta 2, accessory subunit. (580 aa)
TCEA2Transcription elongation factor A2. (356 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (916 aa)
A0A4W2FLF9RING-type domain-containing protein. (108 aa)
POLE3DNA polymerase epsilon 3, accessory subunit. (147 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
CUL4BCullin 4B; Belongs to the cullin family. (734 aa)
KXD1KxDL domain-containing protein. (212 aa)
RFC1Replication factor C subunit 1. (1146 aa)
RPA3Replication protein A3. (121 aa)
A0A4W2EMF1Uncharacterized protein. (286 aa)
AQRRNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1484 aa)
ERCC5ERCC excision repair 5, endonuclease. (1201 aa)
POLR2IRNA polymerase II subunit I. (156 aa)
A0A4W2EIH1Uncharacterized protein. (95 aa)
A0A4W2EHM9Uncharacterized protein. (194 aa)
A0A4W2EGX9Uncharacterized protein. (502 aa)
POLE4DNA polymerase epsilon 4, accessory subunit. (120 aa)
POLD3Uncharacterized protein. (425 aa)
A0A4W2E7G3RNA_pol_L_2 domain-containing protein. (119 aa)
RCBTB2RCC1 and BTB domain containing protein 2. (554 aa)
A0A4W2E0Q1Ubiquitin-like domain-containing protein. (77 aa)
RFC5Replication factor C subunit 5. (527 aa)
A0A4W2DYM9Uncharacterized protein. (98 aa)
A0A4W2DY12RPA_C domain-containing protein. (270 aa)
A0A4W2DUD8Uncharacterized protein. (312 aa)
ISY1Uncharacterized protein. (284 aa)
RFC2Replication factor C subunit 2. (352 aa)
A0A4W2DPH7Ubiquitin-like domain-containing protein. (120 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (780 aa)
PRPF19Pre-mRNA processing factor 19. (504 aa)
ATAD5ATPase family AAA domain containing 5. (1893 aa)
MEIOBMeiosis specific with OB-fold. (472 aa)
POLR2JRNA_pol_L_2 domain-containing protein. (248 aa)
A0A4W2DJ46Uncharacterized protein. (380 aa)
NRDE2NRDE-2, necessary for RNA interference, domain containing. (1155 aa)
CCNHCyclin H; Belongs to the cyclin family. (329 aa)
TCEANC2Transcription elongation factor A N-terminal and central domain containing 2. (223 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
POLKDNA polymerase kappa. (911 aa)
PPIEPeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (301 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (326 aa)
RFC4Replication factor C subunit 4. (364 aa)
A0A4W2D3W4Ubiquitin-like domain-containing protein. (160 aa)
UVSSAUV stimulated scaffold protein A. (691 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1544 aa)
HMGN2Uncharacterized protein. (90 aa)
SPOCD1SPOC domain containing 1. (1104 aa)
UBCUbiquitin C. (1146 aa)
XPAXPA, DNA damage recognition and repair factor. (273 aa)
CUL4ACullin 4A; Belongs to the cullin family. (731 aa)
POLD1DNA polymerase. (1106 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (351 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2289 aa)
RPS27AUbiquitin-like domain-containing protein. (194 aa)
GTF2H3General transcription factor IIH subunit 3. (402 aa)
A0A4W2C7C3KxDL domain-containing protein. (179 aa)
LOC113881217Uncharacterized protein. (103 aa)
PHF3PHD finger protein 3. (2051 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (2019 aa)
POLR2FUncharacterized protein. (127 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (463 aa)
EP300E1A binding protein p300. (2411 aa)
POLR2ERNA polymerase II subunit E. (288 aa)
POLD4Uncharacterized protein. (315 aa)
ZNF830Zinc finger protein 830. (373 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
DDB1Damage specific DNA binding protein 1. (1506 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
RFC3Replication factor C subunit 3. (356 aa)
UPK3BL2Uncharacterized protein. (329 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1103 aa)
Your Current Organism:
Bos indicus
NCBI taxonomy Id: 30522
Other names: B. indicus x Bos taurus, Bos indicus x Bos taurus, Bos primigenius indicus x Bos primigenius taurus, Bos taurus indicus x Bos taurus taurus, hybrid cattle
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